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MTTSMAKTFSVAIIGAGPGGLALGIFLRKAGFTDFTIFDREDGVGGTWRINTYPGLACDVKSHLYSYSFD LNAHWSRMWSGQEEILQYFERCAQRYRLPDNLQLNTEIVSARWGSETRTWTLTTAGGEEHTFDIVVSAIG LFTQPVMPDLVDEEPFTGTVMHTARWDHSVDLRDARVAVLGTGSTAAQLVPEVAKQAAKVYSVQRSPTWV LPKPDREYTGREKWMFAHIPLAKKIYRTRLWLRSESNISVIENGSDKTEEFKGIALRTLEATVADDELRA KLTPTHPLGCKRLVFATDYLQTLTQPHVEVVSSPARSLRSRSLVTEDGTELDVDVVLCATGYAAADYLGQ IEVRGADDALLSDTWRDGAFAYLGMAVPGYPNFFMLYGPNTNVGSNSVIFMLEAQAHYIVRALKYMRRKN RSYIEVRSDVMTRFLERIDTWMQGTVWLTRCSNYFRAPNGRVVTQWPRSARTFWGLTRRFNPGDYGFDAP SSRSRIRVGAQTSVKQP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2243 | - | - | 100% (507) | cyclohexanone monooxygenase |
| M. vanbaalenii PYR-1 | Mvan_0615 | - | 5e-82 | 36.10% (482) | cyclohexanone monooxygenase |
| M. vanbaalenii PYR-1 | Mvan_3427 | - | 8e-79 | 35.15% (458) | putative monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3075c | - | 7e-85 | 33.47% (481) | monooxygenase |
| M. gilvum PYR-GCK | Mflv_4103 | - | 0.0 | 85.26% (502) | cyclohexanone monooxygenase |
| M. tuberculosis H37Rv | Rv3049c | - | 7e-85 | 33.47% (481) | monooxygenase |
| M. leprae Br4923 | MLBr_00065 | - | 3e-27 | 24.38% (447) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_2077 | - | 9e-97 | 38.03% (476) | monooxygenase |
| M. marinum M | MMAR_0403 | - | 0.0 | 71.22% (483) | monooxygenase |
| M. avium 104 | MAV_5119 | - | 0.0 | 73.55% (484) | lipolytic enzyme |
| M. smegmatis MC2 155 | MSMEG_2567 | - | 0.0 | 75.98% (483) | monooxygenase |
| M. thermoresistible (build 8) | TH_3452 | - | 0.0 | 71.43% (497) | PUTATIVE lipolytic enzyme |
| M. ulcerans Agy99 | MUL_1053 | - | 0.0 | 70.60% (483) | monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3075c|M.bovis_AF2122/97 MSIADTAAKPSTPSPANQPPVRTRAVIIGTGFSGLGMAIALQ-KQG-VDF
Rv3049c|M.tuberculosis_H37Rv MSIADTAAKPSTPSPANQPPVRTRAVIIGTGFSGLGMAIALQ-KQG-VDF
MAB_2077|M.abscessus_ATCC_1997 -----MSSNFATACRAYDP----SIVIIGAGFAGVAMAHRLK-KDGFTNF
Mvan_2243|M.vanbaalenii_PYR-1 --------------MTTSMAKTFSVAIIGAGPGGLALGIFLR-KAGFTDF
Mflv_4103|M.gilvum_PYR-GCK ------------------MAKSLSVGIIGAGPGGLALGIFLR-RAGFDDF
MSMEG_2567|M.smegmatis_MC2_155 ---------------MSADRMSMSIGIIGAGPGGLALGIFLK-KAGFRDF
TH_3452|M.thermoresistible__bu ------------------MARNLSVGIIGAGPGGIALGIFLR-RAGFTDF
MMAR_0403|M.marinum_M ------------------MTSPLSVGIIGAGPGGLALGILLK-NRGFENF
MUL_1053|M.ulcerans_Agy99 ------------------MTSPLSVGIIGAGPGGLALGILLK-NRGFENF
MAV_5119|M.avium_104 --------------MPADPMSELSIGIIGAGPGGLALGILLS-QAGFDDF
MLBr_00065|M.leprae_Br4923 -------------MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNKSY
*:*:* .*:. . * . .:
Mb3075c|M.bovis_AF2122/97 VILEKADDVGGTWRDNTYPGCACDIPSHLYSFSFEPKADWKHLFSYWDEI
Rv3049c|M.tuberculosis_H37Rv VILEKADDVGGTWRDNTYPGCACDIPSHLYSFSFEPKADWKHLFSYWDEI
MAB_2077|M.abscessus_ATCC_1997 TILEKAADIGGVWRDNTYPGAACDVPSALYSLSYKPNPRWSRRYAEQPEI
Mvan_2243|M.vanbaalenii_PYR-1 TIFDREDGVGGTWRINTYPGLACDVKSHLYSYSFDLNAHWSRMWSGQEEI
Mflv_4103|M.gilvum_PYR-GCK TIFDREDGVGGTWRINTYPGLACDVKSHLYSYSFDLNAHWSRLWSGQKEI
MSMEG_2567|M.smegmatis_MC2_155 TIFDREDGVGGTWRINTYPGLACDVKSHLYSYSFDLNADWTRLWSSQPEI
TH_3452|M.thermoresistible__bu TIFDREDGVGGTWRINTYPGLACDVKSHLYSYSFELNSEWTRLWPAQPEI
MMAR_0403|M.marinum_M TIFDRESDVGGTWRINTYPGLACDVKSHLYSYSFDLNPGWSRLWSGQPEI
MUL_1053|M.ulcerans_Agy99 NIFDRESDVGGTWRINTYPGLACDVKSHLYSYSFDLNPGWSGLWSGQPEI
MAV_5119|M.avium_104 TIFDREDGVGGTWRINTYPGLACDVKSHLYSYSFDLNAHWSRLWSGQPEI
MLBr_00065|M.leprae_Br4923 VILEKRAGMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTKCQAIADGKP-I
*::: .:**.* *** .* . : . *
Mb3075c|M.bovis_AF2122/97 LGYLKGVTDKYGLRRYIEFNSLVDRGYWDDDECRWHVFTADGRE-----Y
Rv3049c|M.tuberculosis_H37Rv LGYLKGVTDKYGLRRYIEFNSLVDRGYWDDDECRWHVFTADGRE-----Y
MAB_2077|M.abscessus_ATCC_1997 LKYLQQLVESGGLAAHLRTQTEVVAMTFDDQLGRWTLVTNSNET-----I
Mvan_2243|M.vanbaalenii_PYR-1 LQYFERCAQRYRLPDNLQLNTEIVSARWGSETRTWTLTTAGGEE-----H
Mflv_4103|M.gilvum_PYR-GCK LEYFERCAQRYRLQEKLRCNTEIVSARWVPSERRWRLRTSTGAE-----H
MSMEG_2567|M.smegmatis_MC2_155 LAYFERCAQRHQLESHLVLGTEITSARWDTDG--WVLTTSGGDE-----Q
TH_3452|M.thermoresistible__bu LRYFERCAQRHRLGPHLRLNTEITSARWNPTSRQWMLTTGAGEQ-----H
MMAR_0403|M.marinum_M LAYFQRCADRYGLRPHLRLSTEIRSARWESQTRQWTLSTADGEQ-----H
MUL_1053|M.ulcerans_Agy99 LAYFQRCADRYELRPHLRLGTEIRSARWESQTRQWTLSTADGEQ-----H
MAV_5119|M.avium_104 LDYFQRCADKYGLGPHLRLGTEIRSAHWDADTQRWRLTTASGHR-----H
MLBr_00065|M.leprae_Br4923 LEYIKSTAVMHGIDKYIRLNHKVTGADWSSIENRWTVQVENNGTPRMISC
* *:: . : : : : * : . .
Mb3075c|M.bovis_AF2122/97 VAQFLISGAGALHIPSFPEIAGRDEFAGPAFHSAQWDHSIDLTGKRVAIV
Rv3049c|M.tuberculosis_H37Rv VAQFLISGAGALHIPSFPEIAGRDEFAGPAFHSAQWDHSIDLTGKRVAIV
MAB_2077|M.abscessus_ATCC_1997 TCDVVVSAVGQLSLPHVPVIADADTFQGPRFHSARWDRSVSLRGKQVAVI
Mvan_2243|M.vanbaalenii_PYR-1 TFDIVVSAIGLFTQPVMPDLVDEEPFTGTVMHTARWDHSVDLRDARVAVL
Mflv_4103|M.gilvum_PYR-GCK SFDVVVSAVGMFTQPVMPDLVEEEPFTGTVMHTARWDHSVDLRGARVAVL
MSMEG_2567|M.smegmatis_MC2_155 RFDFVVSAVGLFTQPLLPDLVEEEPFTGTVLHTARWDHSIPLAGKKIAVL
TH_3452|M.thermoresistible__bu NFDVVVSAVGMFTRPVMPDLVEEEPFTGTLMHSARWDHGIDLHGKRIAVL
MMAR_0403|M.marinum_M QFSVVVSAVGIFSRPAYPDLVEQQRFTGTVMHSSRWDHSVPLAGARIAVL
MUL_1053|M.ulcerans_Agy99 QFSVVVSVVGIFSRPAYPDLVEQQRFTGTVMHSSRWDHSVPLAGARIAVL
MAV_5119|M.avium_104 HFDVVVSAVGLFTRPLLPELVEEEPFTGTVMHSARWDHSIPLHGKRIAVL
MLBr_00065|M.leprae_Br4923 SFLFLCSGYYNYEQGYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNIVVI
.: * * : : * *. :*. :* ..: .:.::
Mb3075c|M.bovis_AF2122/97 GTGASAIQIVPEIVGQ-VAELQLYQRTPPWVVPRTNEELPVSLRRALRTV
Rv3049c|M.tuberculosis_H37Rv GTGASAIQIVPEIVGQ-VAELQLYQRTPPWVVPRTNEELPVSLRRALRTV
MAB_2077|M.abscessus_ATCC_1997 GTGASAIQFVPHIVQE-AEHVTLYQRTAPWILPKWDSRYGVLHDRVSELL
Mvan_2243|M.vanbaalenii_PYR-1 GTGSTAAQLVPEVAKQ-AAKVYSVQRSPTWVLPKPDREYTGREKWMFAHI
Mflv_4103|M.gilvum_PYR-GCK GTGSTAAQLVPEVAKQ-AAAVYSVQRSPTWVLPKPDRPYTDREKWMFAHV
MSMEG_2567|M.smegmatis_MC2_155 GTGSTAAQLVPELAKV-ADTVYSVQRSPTWILPKPDRPYTDRERWVFAHV
TH_3452|M.thermoresistible__bu GTGSTASQLIPELAKI-ADRVYSVQRSPTWILPKPDRPYSDRERWVFRHV
MMAR_0403|M.marinum_M GTGSTAAQLVPELAKV-ADRVYSIQRSPTWILPKPDRPYSRWERWVFAHV
MUL_1053|M.ulcerans_Agy99 GTGSTAAQLVPELAKV-ADRVYSIQRSPTWILPKPDRPYSRWERWVFAHV
MAV_5119|M.avium_104 GTGSTASQLIPELAKV-AERVYSVQRSPTWILPKPDRPYTRWERWAFAHL
MLBr_00065|M.leprae_Br4923 GSGATAVTLVPALANSGAKHVTMLQRSPTYIVSQPAKDKIAARLNRWLPD
*:*::* ::* :. . : **:..:::.:
Mb3075c|M.bovis_AF2122/97 PGLRALLRLGIYWAQEALAYGMTKRPNTLKIIEAYAKYNIRRSVKD-REL
Rv3049c|M.tuberculosis_H37Rv PGLRALLRLGIYWAQEALAYGMTKRPNTLKIIEAYAKYNIRRSVKD-REL
MAB_2077|M.abscessus_ATCC_1997 PMALRLERFAVWLIFELLAVTLVDAKPLSRVLGAIARRHLHRQVAS-PSL
Mvan_2243|M.vanbaalenii_PYR-1 PLAKKIYRTRLWLRSESNISVIENGSDKTEEFKGIALRTLEATVAD-DEL
Mflv_4103|M.gilvum_PYR-GCK PFAKKIYRTRLWLRSESNISVIEHGSDKTQEFKSIALRTLEATVSD-DEL
MSMEG_2567|M.smegmatis_MC2_155 PLAKKIYRTRLWLRSESNISVIEHGSDKTQEFRSIALNMLRSTVTD-DEL
TH_3452|M.thermoresistible__bu PFAKRIYRTRLWLRSEANISVIEDGSEKTEEFKAIALKMLEATVPD-EEM
MMAR_0403|M.marinum_M PFAARLYRTRLWLRSESNISVIEHGSPKTKEFTELALRMLENTVSD-PQL
MUL_1053|M.ulcerans_Agy99 PFAARLYRTRLWLRSESNISVIEHGSPKTKEFTELALRMLENTVSD-PQL
MAV_5119|M.avium_104 PLAKKLYRTRLWLRSESNISVIEHGSEKTGQFTNIALGLLEASVPD-EEL
MLBr_00065|M.leprae_Br4923 KYAYTAVRWKNILRQSALYGACQKWP---QRMRNILLGHVARRLPKGYDV
* . . : : : . .:
Mb3075c|M.bovis_AF2122/97 RRKLTPRYRIGCKRILNSS--TYYPAVADPKTELITDRIDRITHDGIVTA
Rv3049c|M.tuberculosis_H37Rv RRKLTPRYRIGCKRILNSS--TYYPAVADPKTELITDRIDRITHDGIVTA
MAB_2077|M.abscessus_ATCC_1997 REQLMPSDAPGCKRVLFSN--DYYPAIASDRVSLVPKAIAELCDNGVKTV
Mvan_2243|M.vanbaalenii_PYR-1 RAKLTPTHPLGCKRLVFAT--DYLQTLTQPHVEVVSSPARSLRSRSLVTE
Mflv_4103|M.gilvum_PYR-GCK RARLTPDHPLGCKRLVFAT--DYLKTLTEPHVDVVSSPARALRSRSLVTE
MSMEG_2567|M.smegmatis_MC2_155 RERLTPDHPLGCKRLVFSS--DFIPTLTRPNVEVVSSPARALRSRSLVTE
TH_3452|M.thermoresistible__bu RRRLTPDHPLGCKRLVFSS--DYLAALMRPNVEVVSSPARALRGDTLITE
MMAR_0403|M.marinum_M RRQLTPDHPMGCKRLVFSS--EFLTALARPNVELVTSPARYLRQRSLVTA
MUL_1053|M.ulcerans_Agy99 RRQLTPDHPMGCKRLVFSS--EFLTALTRPNVELVTSPARYLRQRSLVTA
MAV_5119|M.avium_104 RRKLTPDHPMGCKRLVFSS--DYLPALTRPNVEVLTSPARSLRRRSLVTE
MLBr_00065|M.leprae_Br4923 QKHFGPHYNPWEQRLCLVPDGDLFRAIRKGTVDMVTDAIDRFTSTGIRLK
: :: * :*: :: ..::.. : :
Mb3075c|M.bovis_AF2122/97 DGTGREVFREADVIVYATGFHVTDSYTYVQIKGRHGEDLVDRWNREGIGA
Rv3049c|M.tuberculosis_H37Rv DGTGREVFREADVIVYATGFHVTDSYTYVQIKGRHGEDLVDRWNREGIGA
MAB_2077|M.abscessus_ATCC_1997 DG----EFRPADVVIYGTGFRATDFLAPMSVRGSRGVSLAEVWKTQAY-A
Mvan_2243|M.vanbaalenii_PYR-1 DGTE----LDVDVVLCATGYAAADYLGQIEVRGADDALLSDTWR-DGAFA
Mflv_4103|M.gilvum_PYR-GCK DGTE----LDVDVVLCATGYAAADYLGQIDVRGADDIPLSQTWR-DGAFA
MSMEG_2567|M.smegmatis_MC2_155 DGRE----LDVDIVACATGYAAADYLGQIEVTGEGGIRLHDVWR-DGAYA
TH_3452|M.thermoresistible__bu DGTE----RRVDVVVCATGYAAADYLGQIEVVGERQRSLREVWR-DGAYA
MMAR_0403|M.marinum_M DGAE----YDVDVVVCATGYAAADYLGQLEVLGEDGAGLHEVWR-DGAHA
MUL_1053|M.ulcerans_Agy99 DGAE----YDVDVVVCATGYAAADYLGQLEVLGEDGAGLHEVWR-DGAHA
MAV_5119|M.avium_104 DGTE----REVDLVVCATGYAAADYLGELDVTGEHGVTLREVWR-DGAYA
MLBr_00065|M.leprae_Br4923 SGNE----LRADIIVTATGLNLQLFGGAVATVDGQPVDLAQTMS------
.* .*:: .** : . * :
Mb3075c|M.bovis_AF2122/97 HRGITVANMPNLFFLLGPNTGLGHNSVVFMIESQIHYVADAIAKCDRMGV
Rv3049c|M.tuberculosis_H37Rv HRGITVANMPNLFFLLGPNTGLGHNSVVFMIESQIHYVADAIAKCDRMGV
MAB_2077|M.abscessus_ATCC_1997 YLGITVPMFPNLFLLYGPNTNVGSGSILYMIESQVRHIATLIKAVAAHPG
Mvan_2243|M.vanbaalenii_PYR-1 YLGMAVPGYPNFFMLYGPNTNVGSNSVIFMLEAQAHYIVRALKYMRRKNR
Mflv_4103|M.gilvum_PYR-GCK YLGMSVPGYPNFFMLYGPNTNVGSNSVIFVLEAQARYIVRALKYLRRRNR
MSMEG_2567|M.smegmatis_MC2_155 YLGMTVPGFPNFFMLYGPNTNVGSNSVIFVLEAQARYVVRALKHLRRRRK
TH_3452|M.thermoresistible__bu YLGMTVPGFPNFFMLYGPNTNVGSNSVLFILEAQARYVVKALKRLRRRDT
MMAR_0403|M.marinum_M YLGMAVPGFPNFFMLYGPNTNVGSNSVIFMLEAQARYIVAALAHLRRKSK
MUL_1053|M.ulcerans_Agy99 YLGMAVPGFPNFFMLCGPNTNVGSNSVIFMLEAQARYIVAALAHLRRKSK
MAV_5119|M.avium_104 YLGMAVPGFPNFFMLYGPNTNVGSNSVIFVLEAQARYIVRALKYLRRHRR
MLBr_00065|M.leprae_Br4923 YKGMMLSGLPNMIYTVGYTN----ASWTLKADLVSEFFCRLLNYMNANDF
: *: :. **:: * .. * : ... :
Mb3075c|M.bovis_AF2122/97 QALAPTREAQDRFNQELQRRLAGSVWNSGGCRSWYLDEHGKNTVLWCGYT
Rv3049c|M.tuberculosis_H37Rv QALAPTREAQDRFNQELQRRLAGSVWNSGGCRSWYLDEHGKNTVLWCGYT
MAB_2077|M.abscessus_ATCC_1997 HAIDVRTESAQRYNTRLRRRLRRSVWAL--CASWYRTSSGEIPTNWPGPT
Mvan_2243|M.vanbaalenii_PYR-1 SYIEVRSDVMTRFLERIDTWMQGTVWLT-RCSNYFRAPNGRVVTQWPRSA
Mflv_4103|M.gilvum_PYR-GCK SYIEVRSDVMKRYLDKIDSWMQGTVWLT-RCSNYFRAPNGRVVTQWPRSA
MSMEG_2567|M.smegmatis_MC2_155 SYVAVKPEVMAQFIADIDRWMQGTVWLT-RCSSYFRAPNGRVVTQWPRSA
TH_3452|M.thermoresistible__bu SYIAVRPDTAAAFLAKVDQWMQGKVWST-QCNNYFRAPNGRVVTQWPRSA
MMAR_0403|M.marinum_M TYIAVRPGVLAEFMAKVDRWMTGTVWTT-ECSNYFRAPNGRVVTQWPRSA
MUL_1053|M.ulcerans_Agy99 TYIAVRPGVLAEFIAKVDRWMTGTVWTT-ECSNYFRAPNGRVVTQWPRSA
MAV_5119|M.avium_104 RYIAVRPAALADFVAKIDRWMVGTVWTT-QCSNYFRAPNGRVVTQWPRSA
MLBr_00065|M.leprae_Br4923 DTVAVEYPGSDVEERPFMDFTPGYVLRS---LDALPKQGSRTPWRLNQNY
: . * . ..
Mb3075c|M.bovis_AF2122/97 WQYWLTTRSVNPAEYRFFGIGNGLSSDRATVAAAN---------------
Rv3049c|M.tuberculosis_H37Rv WQYWLTTRSVNPAEYRFFGIGNGLSSDRATVAAAN---------------
MAB_2077|M.abscessus_ATCC_1997 LVYRLLTRKPHSGDYVLRNVGRLKVGDPAEPSLAD---------------
Mvan_2243|M.vanbaalenii_PYR-1 RTFWGLTRRFNPGDYGFDAPSS--RSRIRVGAQTSVKQP-----------
Mflv_4103|M.gilvum_PYR-GCK RDFWALTRWFRAGDYVFEAPSA--RETISVGAQAEAER------------
MSMEG_2567|M.smegmatis_MC2_155 RALWAMTRRFRAADYLFSAPVDGQAQVVEVAAHETVG-------------
TH_3452|M.thermoresistible__bu RAFWAMTRRFRSADYLFEPAPD--MSEVSADARPVASR------------
MMAR_0403|M.marinum_M RSFWGMTRRFKPADFSFQPAAVFAADGGDRNAGQR---------------
MUL_1053|M.ulcerans_Agy99 RSFWGMTRRFKPADFSFQPAAVFAADGGDRNAGQRWPNPRPSIGWTPCCA
MAV_5119|M.avium_104 RAFWSMTRRFRPADYRFQAPAVRVPAPAS-EADAR---------------
MLBr_00065|M.leprae_Br4923 LRDIRLIRRGKVADEGLLFAKKTTPVTV----------------------
* . .: :
Mb3075c|M.bovis_AF2122/97 --------------
Rv3049c|M.tuberculosis_H37Rv --------------
MAB_2077|M.abscessus_ATCC_1997 --------------
Mvan_2243|M.vanbaalenii_PYR-1 --------------
Mflv_4103|M.gilvum_PYR-GCK --------------
MSMEG_2567|M.smegmatis_MC2_155 --------------
TH_3452|M.thermoresistible__bu --------------
MMAR_0403|M.marinum_M --------------
MUL_1053|M.ulcerans_Agy99 PSRRRESTSPRSRS
MAV_5119|M.avium_104 --------------
MLBr_00065|M.leprae_Br4923 --------------