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MSSNFATACRAYDPSIVIIGAGFAGVAMAHRLKKDGFTNFTILEKAADIGGVWRDNTYPGAACDVPSALY SLSYKPNPRWSRRYAEQPEILKYLQQLVESGGLAAHLRTQTEVVAMTFDDQLGRWTLVTNSNETITCDVV VSAVGQLSLPHVPVIADADTFQGPRFHSARWDRSVSLRGKQVAVIGTGASAIQFVPHIVQEAEHVTLYQR TAPWILPKWDSRYGVLHDRVSELLPMALRLERFAVWLIFELLAVTLVDAKPLSRVLGAIARRHLHRQVAS PSLREQLMPSDAPGCKRVLFSNDYYPAIASDRVSLVPKAIAELCDNGVKTVDGEFRPADVVIYGTGFRAT DFLAPMSVRGSRGVSLAEVWKTQAYAYLGITVPMFPNLFLLYGPNTNVGSGSILYMIESQVRHIATLIKA VAAHPGHAIDVRTESAQRYNTRLRRRLRRSVWALCASWYRTSSGEIPTNWPGPTLVYRLLTRKPHSGDYV LRNVGRLKVGDPAEPSLAD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2077 | - | - | 100% (509) | monooxygenase |
| M. abscessus ATCC 19977 | MAB_3920c | - | e-101 | 40.55% (476) | monooxygenase |
| M. abscessus ATCC 19977 | MAB_4476c | - | e-100 | 39.58% (475) | putative monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3075c | - | 4e-99 | 39.00% (500) | monooxygenase |
| M. gilvum PYR-GCK | Mflv_4605 | - | 1e-164 | 54.78% (502) | FAD dependent oxidoreductase |
| M. tuberculosis H37Rv | Rv3049c | - | 4e-99 | 39.00% (500) | monooxygenase |
| M. leprae Br4923 | MLBr_00065 | - | 2e-26 | 26.35% (406) | putative monooxygenase |
| M. marinum M | MMAR_3136 | - | 0.0 | 76.39% (504) | monooxygenase |
| M. avium 104 | MAV_3915 | - | 1e-101 | 40.37% (493) | flavin-containing monooxygenase FMO |
| M. smegmatis MC2 155 | MSMEG_4451 | - | 1e-103 | 41.36% (469) | monooxygenase |
| M. thermoresistible (build 8) | TH_3452 | - | 1e-100 | 39.20% (477) | PUTATIVE lipolytic enzyme |
| M. ulcerans Agy99 | MUL_1880 | - | 3e-99 | 39.63% (482) | monooxygenase |
| M. vanbaalenii PYR-1 | Mvan_2243 | - | 1e-96 | 38.03% (476) | cyclohexanone monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2077|M.abscessus_ATCC_1997 ------------MSSNFATACRAYDPSIVIIGAGFAGVAMAHRLKKDG-F
MMAR_3136|M.marinum_M ------------MTGGFARDPRGHDPSIVIIGAGVAGIAMAHQLKRDG-F
Mflv_4605|M.gilvum_PYR-GCK ---------MKPVKREPTQDNPPGNPSIVIIGAGFAGITLALRLKRAG-F
TH_3452|M.thermoresistible__bu ---------------------MARNLSVGIIGAGPGGIALGIFLRRAG-F
Mvan_2243|M.vanbaalenii_PYR-1 -----------------MTTSMAKTFSVAIIGAGPGGLALGIFLRKAG-F
Mb3075c|M.bovis_AF2122/97 ---MSIADTAAKPSTPSPANQPPVRTRAVIIGTGFSGLGMAIALQKQG--
Rv3049c|M.tuberculosis_H37Rv ---MSIADTAAKPSTPSPANQPPVRTRAVIIGTGFSGLGMAIALQKQG--
MAV_3915|M.avium_104 MTDVVT-HTETAPTPAAKAAKP-VHTRAVIIGTGFSGLGMAIALQKQG--
MUL_1880|M.ulcerans_Agy99 MTDVVIPSTETTASGEPQAPTPPVKTRAVIIGTGFSGLGMAIALQKQG--
MSMEG_4451|M.smegmatis_MC2_155 -----------MSAPASSTPTLPASVHTLVVGAGFAGLAAAAAVLREDPR
MLBr_00065|M.leprae_Br4923 ----------------MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPN
::*:* .*: . :
MAB_2077|M.abscessus_ATCC_1997 TNFTILEKAADIGGVWRDNTYPGAACDVPSALYSLSYKPNPRWSRRYAEQ
MMAR_3136|M.marinum_M TNFTMVEKAADIGGVWRDNTYPGAACDVPSALYSLSDKPNTRWSRRYAEQ
Mflv_4605|M.gilvum_PYR-GCK DRVLIVEKGDGVGGVWRENTYPGAACDVPSQLYSISSAPNPRWGRRYAEQ
TH_3452|M.thermoresistible__bu TDFTIFDREDGVGGTWRINTYPGLACDVKSHLYSYSFELNSEWTRLWPAQ
Mvan_2243|M.vanbaalenii_PYR-1 TDFTIFDREDGVGGTWRINTYPGLACDVKSHLYSYSFDLNAHWSRMWSGQ
Mb3075c|M.bovis_AF2122/97 VDFVILEKADDVGGTWRDNTYPGCACDIPSHLYSFSFEPKADWKHLFSYW
Rv3049c|M.tuberculosis_H37Rv VDFVILEKADDVGGTWRDNTYPGCACDIPSHLYSFSFEPKADWKHLFSYW
MAV_3915|M.avium_104 VGFVILEKADDIGGTWRDNSYPGCACDIPSHLYSFSFEPKPDWKNPFSYQ
MUL_1880|M.ulcerans_Agy99 VDFVILEKSDDVGGTWRDNSYPGCACDIPSHLYSFSFEPKPDWRNPFSYQ
MSMEG_4451|M.smegmatis_MC2_155 ADLLIIERADEVGGTWRDNTYPGCACDVPTSLYSFSFAPSAKWSHTFARQ
MLBr_00065|M.leprae_Br4923 KSYVILEKRAGMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTKCQAIADGK
:.:: :**.* *** .* . .
MAB_2077|M.abscessus_ATCC_1997 PEILKYLQQLVESGGLAAHLRTQTEVVAMTFDDQLGRWTLVT---NSNET
MMAR_3136|M.marinum_M PEILQYLRRLVLADGMDLHLRTRTEVVEMTFDEQAGRWRLVT---GSSET
Mflv_4605|M.gilvum_PYR-GCK GDILAYLRRVADESGLLSLLRTKTEIAKAAFDERTNTWRLTT---TTSQE
TH_3452|M.thermoresistible__bu PEILRYFERCAQRHRLGPHLRLNTEITSARWNPTSRQWMLTT---GAGEQ
Mvan_2243|M.vanbaalenii_PYR-1 EEILQYFERCAQRYRLPDNLQLNTEIVSARWGSETRTWTLTT---AGGEE
Mb3075c|M.bovis_AF2122/97 DEILGYLKGVTDKYGLRRYIEFNSLVDRGYWDDDECRWHVFT---ADGRE
Rv3049c|M.tuberculosis_H37Rv DEILGYLKGVTDKYGLRRYIEFNSLVDRGYWDDDECRWHVFT---ADGRE
MAV_3915|M.avium_104 PEIWDYLKGVTEKYGLRRYIEFNSLVDRAHWDDDEHRWHVFT---TDGRE
MUL_1880|M.ulcerans_Agy99 PEIWDYLKGVTEKYGLRRYVEFNSLVDRAYWDDEECRWHVFT---SDGRE
MSMEG_4451|M.smegmatis_MC2_155 PEIHRYLTSVADQTGLRHHLVTGCELLGAAWDDDEQRWRVRT---SLG-M
MLBr_00065|M.leprae_Br4923 P-ILEYIKSTAVMHGIDKYIRLNHKVTGADWSSIENRWTVQVENNGTPRM
* *: . : : : :. * : .
MAB_2077|M.abscessus_ATCC_1997 ITCDVVVSAVGQLSLPH--VPVIADADTFQGPRFHSARWDRSVSLRGKQV
MMAR_3136|M.marinum_M IWCDVVISAVGQLSRPH--TPNIAGEDTFEGPRFHSARWDHSVSLRGKEV
Mflv_4605|M.gilvum_PYR-GCK LECDVVISAVGQLSRPS--VPDIPGISGFAGPSFHSANWDHDLNLSGKRL
TH_3452|M.thermoresistible__bu HNFDVVVSAVGMFTRPV--MPDLVEEEPFTGTLMHSARWDHGIDLHGKRI
Mvan_2243|M.vanbaalenii_PYR-1 HTFDIVVSAIGLFTQPV--MPDLVDEEPFTGTVMHTARWDHSVDLRDARV
Mb3075c|M.bovis_AF2122/97 YVAQFLISGAGALHIPS--FPEIAGRDEFAGPAFHSAQWDHSIDLTGKRV
Rv3049c|M.tuberculosis_H37Rv YVAQFLISGAGALHIPS--FPEIAGRDEFAGPAFHSAQWDHSIDLTGKRV
MAV_3915|M.avium_104 YVAQFLISGAGALHIPS--LPDIEGRDEFAGPAFHSAEWDHTVDLTGKRV
MUL_1880|M.ulcerans_Agy99 YVAQFLISGAGALHIPS--SPEIEGREEFAGPAFHSAEWDHSVDLTGKRV
MSMEG_4451|M.smegmatis_MC2_155 VTATVLVAATGALSTPK--LPDVPGLDRFGGTVFHSATWNHDHDLTDERV
MLBr_00065|M.leprae_Br4923 ISCSFLFLCSGYYNYEQGYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNI
.:. * * . . * *. :*. * . . .:
MAB_2077|M.abscessus_ATCC_1997 AVIGTGASAIQFVPHIVQE-AEHVTLYQRTAPWILPKWDSRYGVLHDRVS
MMAR_3136|M.marinum_M AVIGTGASAIQFVPRIAHE-AQRVTLYQRTAPWILPKWDSRYGRLHQQLI
Mflv_4605|M.gilvum_PYR-GCK AVVGTGASSVQFVPVVAAG-AEHLDVFQRSAPWVLPKFDRQYGGRHHQLL
TH_3452|M.thermoresistible__bu AVLGTGSTASQLIPELAKI-ADRVYSVQRSPTWILPKPDRPYSDRERWVF
Mvan_2243|M.vanbaalenii_PYR-1 AVLGTGSTAAQLVPEVAKQ-AAKVYSVQRSPTWVLPKPDREYTGREKWMF
Mb3075c|M.bovis_AF2122/97 AIVGTGASAIQIVPEIVGQ-VAELQLYQRTPPWVVPRTNEELPVSLRRAL
Rv3049c|M.tuberculosis_H37Rv AIVGTGASAIQIVPEIVGQ-VAELQLYQRTPPWVVPRTNEELPVSLRRAL
MAV_3915|M.avium_104 AVIGTGASAIQIVPEIVGQ-VAELQLYQRTPPWVVPRSNPEIPPAVRAAM
MUL_1880|M.ulcerans_Agy99 AIIGAGASAIQIVPEIVEQ-VGELQLYQRTPPWVVPRSNPEIPPALRRAM
MSMEG_4451|M.smegmatis_MC2_155 AVVGTGASAVQFVPEIADR-TAHLTVFQRTPAWVLPRLDRTLGRLERALY
MLBr_00065|M.leprae_Br4923 VVIGSGATAVTLVPALANSGAKHVTMLQRSPTYIVSQPAK--DKIAARLN
.::*:*::: ::* :. . .: **:..:::.:
MAB_2077|M.abscessus_ATCC_1997 ELLPMALRLERFAVWLIFELLAVTLVDAKPLSRVLGAIARRHLHRQVASP
MMAR_3136|M.marinum_M KVLPLWLRLERFAVWLIFEVLAVTLVDAKPLSRILGAVARYHLHRQVADP
Mflv_4605|M.gilvum_PYR-GCK RKLPILRLSERLMIWTIFEFLALALVDAKPVARVLGVIALRHLGRQVSDA
TH_3452|M.thermoresistible__bu RHVPFAKRIYRTRLWLRSEANISVIEDGSEKTEEFKAIALKMLEATVPDE
Mvan_2243|M.vanbaalenii_PYR-1 AHIPLAKKIYRTRLWLRSESNISVIENGSDKTEEFKGIALRTLEATVADD
Mb3075c|M.bovis_AF2122/97 RTVPGLRALLRLGIYWAQEALAYGMTKRPNTLKIIEAYAKYNIRRSVKDR
Rv3049c|M.tuberculosis_H37Rv RTVPGLRALLRLGIYWAQEALAYGMTKRPNTLKIIEAYAKYNIRRSVKDR
MAV_3915|M.avium_104 ENVPGLRALVRLAIYWGQEALAFGMTKRPNLLKVIEAYAKYNIRRSVKDK
MUL_1880|M.ulcerans_Agy99 ENVPGLRALARLGIYWAQEALAFGMTKRPNVLKVGEAYAKYNIRRSVKDR
MSMEG_4451|M.smegmatis_MC2_155 RRIPLSQRLVRGMVYIYREGYLALLAHLTWLLPLLEIIAKTQLRRQVPDP
MLBr_00065|M.leprae_Br4923 RWLPDKYAYTAVRWKNILRQSALYGACQKWPQRMRNILLGHVARRLPKGY
:* . .
MAB_2077|M.abscessus_ATCC_1997 SLREQLMPSDAPGCKRVLFS--NDYYPAIASDRVSLVPKAIAELCDNGVK
MMAR_3136|M.marinum_M MLRRQLTPSDAPGCKRVLFS--NDYYPAIANGEVSLVTNAVAKLCDKGVV
Mflv_4605|M.gilvum_PYR-GCK RLRSHLTPDYAPGCKRILFS--SDYYPALARPNVLLVTDDIQAVEPGGIR
TH_3452|M.thermoresistible__bu EMRRRLTPDHPLGCKRLVFS--SDYLAALMRPNVEVVSSPARALRGDTLI
Mvan_2243|M.vanbaalenii_PYR-1 ELRAKLTPTHPLGCKRLVFA--TDYLQTLTQPHVEVVSSPARSLRSRSLV
Mb3075c|M.bovis_AF2122/97 ELRRKLTPRYRIGCKRILNS--STYYPAVADPKTELITDRIDRITHDGIV
Rv3049c|M.tuberculosis_H37Rv ELRRKLTPRYRIGCKRILNS--STYYPAVADPKTELITDRIDRITHDGIV
MAV_3915|M.avium_104 ELRRKLTPHYRIGCKRILNS--STYYGAVADPKTELVTDHIARITPDGIV
MUL_1880|M.ulcerans_Agy99 ELRRKLTPHYRIGCKRILNS--SSYYPAVANPKTRLITDRIARITRNGIV
MSMEG_4451|M.smegmatis_MC2_155 ALRRALTPDFRIGCKRILLT--NDWLPTLARDDVEVVTTALTEVTETGVR
MLBr_00065|M.leprae_Br4923 DVQKHFGPHYNPWEQRLCLVPDGDLFRAIRKGTVDMVTDAIDRFTSTGIR
:: : * :*: :: . ::. . :
MAB_2077|M.abscessus_ATCC_1997 TVDG----EFRPADVVIYGTGFRATDFLAPMSVRGSRGVSLAEVWKT-QA
MMAR_3136|M.marinum_M TDDG----VLHRADVVIYGTGFRATDFLAPMRVRGWGGVTLDEVWGT-QA
Mflv_4605|M.gilvum_PYR-GCK TVNG----DFHAADVIIYGTGFSATEFLSPMEVYGRSDRKLSDVWAD-GA
TH_3452|M.thermoresistible__bu TEDG----TERRVDVVVCATGYAAADYLGQIEVVGERQRSLREVWRD-GA
Mvan_2243|M.vanbaalenii_PYR-1 TEDG----TELDVDVVLCATGYAAADYLGQIEVRGADDALLSDTWRD-GA
Mb3075c|M.bovis_AF2122/97 TADGTGREVFREADVIVYATGFHVTDSYTYVQIKGRHGEDLVDRWNREGI
Rv3049c|M.tuberculosis_H37Rv TADGTGREVFREADVIVYATGFHVTDSYTYVQIKGRHGEDLVDRWNREGI
MAV_3915|M.avium_104 TADG----THRPVDVIVYATGFHVTDSYTYVQIKGLHGEDLVDRWNREGI
MUL_1880|M.ulcerans_Agy99 TADG----VEHQADVIVYATGFHVTDSYTYVQIKGQHGEDLVDRWNREGI
MSMEG_4451|M.smegmatis_MC2_155 DGTG----RLHDVDTIIFATGFTPTEPPVAHQLTGVTGTTLAAHWAG-SP
MLBr_00065|M.leprae_Br4923 LKSG----NELRADIIVTATGLNLQLFGGAVATVDGQPVDLAQ------T
* .* :: .** . *
MAB_2077|M.abscessus_ATCC_1997 YAYLGITVPMFPNLFLLYGPNTNVGSGSILYMIESQVRHIATLIKAVAAH
MMAR_3136|M.marinum_M HAYLGITVPMFPNLFLLYGPNTNVGSGSIIYMIESQVRYVGALIKILASD
Mflv_4605|M.gilvum_PYR-GCK HAYYGLSVPEFPNFLMMYGPNTNVGSGSIVYMLESQARHIVRLMKVLRAH
TH_3452|M.thermoresistible__bu YAYLGMTVPGFPNFFMLYGPNTNVGSNSVLFILEAQARYVVKALKRLRRR
Mvan_2243|M.vanbaalenii_PYR-1 FAYLGMAVPGYPNFFMLYGPNTNVGSNSVIFMLEAQAHYIVRALKYMRRK
Mb3075c|M.bovis_AF2122/97 GAHRGITVANMPNLFFLLGPNTGLGHNSVVFMIESQIHYVADAIAKCDRM
Rv3049c|M.tuberculosis_H37Rv GAHRGITVANMPNLFFLLGPNTGLGHNSVVFMIESQIHYVADAIAKCDRM
MAV_3915|M.avium_104 GAHRGITVADVPNLFFLLGPNTGLGHNSVVFMIESQIRYVADAIATCDKL
MUL_1880|M.ulcerans_Agy99 GAHRGIAVADVPNLFFLLGPNTGLGHNSVVFMIESQIHYVADAIAKCDKR
MSMEG_4451|M.smegmatis_MC2_155 SAHLGITVPGFPNLFLMYGPNTNLGHSSIVYMLESQAAYLAAALRVMRAE
MLBr_00065|M.leprae_Br4923 MSYKGMMLSGLPNMIYTVGYTN----ASWTLKADLVSEFFCRLLNYMNAN
:: *: :. **:: * .. * : .. :
MAB_2077|M.abscessus_ATCC_1997 PGHAIDVRTESAQRYNTRLRRRLRRSVW--ALCASWYRTSSGEIPTNWPG
MMAR_3136|M.marinum_M PGRTVDVRPDIEQSYNTRLSRRLRRSVW--ALCASWYTTSSGAIPTNWPG
Mflv_4605|M.gilvum_PYR-GCK PGSVIEVRADVEKRFNDRLSRRLDRSVW--TMCTSWYRSARGSISTNWPS
TH_3452|M.thermoresistible__bu DTSYIAVRPDTAAAFLAKVDQWMQGKVWS-TQCNNYFRAPNGRVVTQWPR
Mvan_2243|M.vanbaalenii_PYR-1 NRSYIEVRSDVMTRFLERIDTWMQGTVWL-TRCSNYFRAPNGRVVTQWPR
Mb3075c|M.bovis_AF2122/97 GVQALAPTREAQDRFNQELQRRLAGSVWNSGGCRSWYLDEHGKNTVLWCG
Rv3049c|M.tuberculosis_H37Rv GVQALAPTREAQDRFNQELQRRLAGSVWNSGGCRSWYLDEHGKNTVLWCG
MAV_3915|M.avium_104 GAQALAPTRAAQDRFNDELQRRLGPSVWNSGGCSSWYLDEHGKNTVLWGG
MUL_1880|M.ulcerans_Agy99 GAQALAPTRAAQDRFNEELQRRLAGSVWNSGGCSSWYLDEHGRNTVLWCG
MSMEG_4451|M.smegmatis_MC2_155 GLASIDVRPDAERTYNEWINDALTNTVWNSGGCSSWYLDSRGRNSVMWPT
MLBr_00065|M.leprae_Br4923 DFDTVAVEYPGSDVEERPFMDFTPGYVLR---SLDALPKQGSRTPWRLNQ
: . * . . .
MAB_2077|M.abscessus_ATCC_1997 PTLVYRLLTRKPHSGDYVLRN------------------VGRLKVGDPAE
MMAR_3136|M.marinum_M PTFAYRILTRKPRSHDYLFRH------------------VERLQLDGPSE
Mflv_4605|M.gilvum_PYR-GCK PTFLYRLRARRPKRRAYVLSRPAP---------------ANSSRRGTPEP
TH_3452|M.thermoresistible__bu SARAFWAMTRRFRSADYLFEPA-----------------PDMSEVSADAR
Mvan_2243|M.vanbaalenii_PYR-1 SARTFWGLTRRFNPGDYGFDAP-----------------SSRSRIRVGAQ
Mb3075c|M.bovis_AF2122/97 YTWQYWLTTRSVNPAEYRFFGIGNGLS------------SDRATVAAAN-
Rv3049c|M.tuberculosis_H37Rv YTWQYWLTTRSVNPAEYRFFGIGNGLS------------SDRATVAAAN-
MAV_3915|M.avium_104 YTWEYWRATRAVKPEEYQFYGIG-----------------SRAGV-----
MUL_1880|M.ulcerans_Agy99 YTWQYWLATRSVKPEEYQFFKAG-----------------AKSSVNG---
MSMEG_4451|M.smegmatis_MC2_155 FTFRFRARTRSFDVINYDTLRTRQQIRGVEQRCESQLADADREILAGQIR
MLBr_00065|M.leprae_Br4923 NYLRDIRLIRRGKVADEGLLFAK-----------------KTTPVTV---
*
MAB_2077|M.abscessus_ATCC_1997 P--SLAD--------------------------------------
MMAR_3136|M.marinum_M NRARLRR--------------------------------------
Mflv_4605|M.gilvum_PYR-GCK ANTHLADMPYAPSGADSVD--------------------------
TH_3452|M.thermoresistible__bu PVASR----------------------------------------
Mvan_2243|M.vanbaalenii_PYR-1 TSVKQP---------------------------------------
Mb3075c|M.bovis_AF2122/97 ---------------------------------------------
Rv3049c|M.tuberculosis_H37Rv ---------------------------------------------
MAV_3915|M.avium_104 ---------------------------------------------
MUL_1880|M.ulcerans_Agy99 ---------------------------------------------
MSMEG_4451|M.smegmatis_MC2_155 LAGEDESVTPSTLRTVRRDQRYMTRGRIHAEVADLLDRTVAMNGE
MLBr_00065|M.leprae_Br4923 ---------------------------------------------