For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTSPLSVGIIGAGPGGLALGILLKNRGFENFNIFDRESDVGGTWRINTYPGLACDVKSHLYSYSFDLNPG WSGLWSGQPEILAYFQRCADRYELRPHLRLGTEIRSARWESQTRQWTLSTADGEQHQFSVVVSVVGIFSR PAYPDLVEQQRFTGTVMHSSRWDHSVPLAGARIAVLGTGSTAAQLVPELAKVADRVYSIQRSPTWILPKP DRPYSRWERWVFAHVPFAARLYRTRLWLRSESNISVIEHGSPKTKEFTELALRMLENTVSDPQLRRQLTP DHPMGCKRLVFSSEFLTALTRPNVELVTSPARYLRQRSLVTADGAEYDVDVVVCATGYAAADYLGQLEVL GEDGAGLHEVWRDGAHAYLGMAVPGFPNFFMLCGPNTNVGSNSVIFMLEAQARYIVAALAHLRRKSKTYI AVRPGVLAEFIAKVDRWMTGTVWTTECSNYFRAPNGRVVTQWPRSARSFWGMTRRFKPADFSFQPAAVFA ADGGDRNAGQRWPNPRPSIGWTPCCAPSRRRESTSPRSRS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1053 | - | - | 100% (530) | monooxygenase |
| M. ulcerans Agy99 | MUL_4873 | - | e-112 | 42.71% (501) | monooxygenase |
| M. ulcerans Agy99 | MUL_0256 | - | 3e-89 | 40.40% (448) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0916 | - | 2e-90 | 36.71% (493) | monooxygenase |
| M. gilvum PYR-GCK | Mflv_4103 | - | 0.0 | 70.66% (484) | cyclohexanone monooxygenase |
| M. tuberculosis H37Rv | Rv0892 | - | 2e-90 | 36.71% (493) | monooxygenase |
| M. leprae Br4923 | MLBr_00065 | - | 1e-26 | 25.50% (400) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_4476c | - | 4e-96 | 37.68% (483) | putative monooxygenase |
| M. marinum M | MMAR_0403 | - | 0.0 | 98.40% (501) | monooxygenase |
| M. avium 104 | MAV_5119 | - | 0.0 | 77.57% (486) | lipolytic enzyme |
| M. smegmatis MC2 155 | MSMEG_2567 | - | 0.0 | 74.32% (479) | monooxygenase |
| M. thermoresistible (build 8) | TH_3452 | - | 0.0 | 73.25% (486) | PUTATIVE lipolytic enzyme |
| M. vanbaalenii PYR-1 | Mvan_2243 | - | 0.0 | 70.60% (483) | cyclohexanone monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0916|M.bovis_AF2122/97 ----MTGRCPTVAVVGAGMSGMCVAITLLSAG-ITDVCIYEKADDVGGTW
Rv0892|M.tuberculosis_H37Rv ----MTGRCPTVAVVGAGMSGMCVAITLLSAG-ITDVCIYEKADDVGGTW
MAB_4476c|M.abscessus_ATCC_199 ----MT----EVLIVGAGFAGLGTAIRLLEKG-IEDFVILERGDDVGGTW
MUL_1053|M.ulcerans_Agy99 -----MTSPLSVGIIGAGPGGLALGILLKNRG-FENFNIFDRESDVGGTW
MMAR_0403|M.marinum_M -----MTSPLSVGIIGAGPGGLALGILLKNRG-FENFTIFDRESDVGGTW
MAV_5119|M.avium_104 -MPADPMSELSIGIIGAGPGGLALGILLSQAG-FDDFTIFDREDGVGGTW
Mflv_4103|M.gilvum_PYR-GCK -----MAKSLSVGIIGAGPGGLALGIFLRRAG-FDDFTIFDREDGVGGTW
Mvan_2243|M.vanbaalenii_PYR-1 -MTTSMAKTFSVAIIGAGPGGLALGIFLRKAG-FTDFTIFDREDGVGGTW
MSMEG_2567|M.smegmatis_MC2_155 --MSADRMSMSIGIIGAGPGGLALGIFLKKAG-FRDFTIFDREDGVGGTW
TH_3452|M.thermoresistible__bu -----MARNLSVGIIGAGPGGIALGIFLRRAG-FTDFTIFDREDGVGGTW
MLBr_00065|M.leprae_Br4923 MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNKSYVILEKRAGMGGTW
: ::*** .*: . * . * :: .:****
Mb0916|M.bovis_AF2122/97 RDNTYPGLTCDVPSRLYQYSFAKNPNWTQMFSRGGEIQDYLRGIAERYGL
Rv0892|M.tuberculosis_H37Rv RDNTYPGLTCDVPSRLYQYSFAKNPNWTQMFSRGGEIQDYLRGIAERYGL
MAB_4476c|M.abscessus_ATCC_199 RDNSYPGAACDIPSLLYSYSFEQNPQWSRAYSGGSEILGYIQRMVDKHQL
MUL_1053|M.ulcerans_Agy99 RINTYPGLACDVKSHLYSYSFDLNPGWSGLWSGQPEILAYFQRCADRYEL
MMAR_0403|M.marinum_M RINTYPGLACDVKSHLYSYSFDLNPGWSRLWSGQPEILAYFQRCADRYGL
MAV_5119|M.avium_104 RINTYPGLACDVKSHLYSYSFDLNAHWSRLWSGQPEILDYFQRCADKYGL
Mflv_4103|M.gilvum_PYR-GCK RINTYPGLACDVKSHLYSYSFDLNAHWSRLWSGQKEILEYFERCAQRYRL
Mvan_2243|M.vanbaalenii_PYR-1 RINTYPGLACDVKSHLYSYSFDLNAHWSRMWSGQEEILQYFERCAQRYRL
MSMEG_2567|M.smegmatis_MC2_155 RINTYPGLACDVKSHLYSYSFDLNADWTRLWSSQPEILAYFERCAQRHQL
TH_3452|M.thermoresistible__bu RINTYPGLACDVKSHLYSYSFELNSEWTRLWPAQPEILRYFERCAQRHRL
MLBr_00065|M.leprae_Br4923 DLFRYPGIRSDSDMYTLGFRFRPWTKCQAIADGKP-ILEYIKSTAVMHGI
*** .* : * . * *:. . : :
Mb0916|M.bovis_AF2122/97 RHRIRFGATVVSARFDD--GRWVLRTDSGTE-----STVDFLISATGVLH
Rv0892|M.tuberculosis_H37Rv RHRIRFGATVVSARFDD--GRWVLRTDSGTE-----STVDFLISATGVLH
MAB_4476c|M.abscessus_ATCC_199 RRFIKFGVDVTGLTFDDSTGMWTADTAAGEI-----FTGRCAVMAAGPLA
MUL_1053|M.ulcerans_Agy99 RPHLRLGTEIRSARWESQTRQWTLSTADGEQ-----HQFSVVVSVVGIFS
MMAR_0403|M.marinum_M RPHLRLSTEIRSARWESQTRQWTLSTADGEQ-----HQFSVVVSAVGIFS
MAV_5119|M.avium_104 GPHLRLGTEIRSAHWDADTQRWRLTTASGHR-----HHFDVVVSAVGLFT
Mflv_4103|M.gilvum_PYR-GCK QEKLRCNTEIVSARWVPSERRWRLRTSTGAE-----HSFDVVVSAVGMFT
Mvan_2243|M.vanbaalenii_PYR-1 PDNLQLNTEIVSARWGSETRTWTLTTAGGEE-----HTFDIVVSAIGLFT
MSMEG_2567|M.smegmatis_MC2_155 ESHLVLGTEITSARWDTDG--WVLTTSGGDE-----QRFDFVVSAVGLFT
TH_3452|M.thermoresistible__bu GPHLRLNTEITSARWNPTSRQWMLTTGAGEQ-----HNFDVVVSAVGMFT
MLBr_00065|M.leprae_Br4923 DKYIRLNHKVTGADWSSIENRWTVQVENNGTPRMISCSFLFLCSGYYNYE
: . : . : * . .
Mb0916|M.bovis_AF2122/97 HPRIPPIAGLDDFRGTVFHSARWDHTVPLLGRRIAVIGTGSTGVQLVCGL
Rv0892|M.tuberculosis_H37Rv HPRIPPIAGLDDFRGTVFHSARWDHTVPLLGRRIAVIGTGSTGVQLVCGL
MAB_4476c|M.abscessus_ATCC_199 NVSWPDIRGLDSYTGHKIHSARWDHDYEMSGKHVAVIGTGASGVQIIPEL
MUL_1053|M.ulcerans_Agy99 RPAYPDLVEQQRFTGTVMHSSRWDHSVPLAGARIAVLGTGSTAAQLVPEL
MMAR_0403|M.marinum_M RPAYPDLVEQQRFTGTVMHSSRWDHSVPLAGARIAVLGTGSTAAQLVPEL
MAV_5119|M.avium_104 RPLLPELVEEEPFTGTVMHSARWDHSIPLHGKRIAVLGTGSTASQLIPEL
Mflv_4103|M.gilvum_PYR-GCK QPVMPDLVEEEPFTGTVMHTARWDHSVDLRGARVAVLGTGSTAAQLVPEV
Mvan_2243|M.vanbaalenii_PYR-1 QPVMPDLVDEEPFTGTVMHTARWDHSVDLRDARVAVLGTGSTAAQLVPEV
MSMEG_2567|M.smegmatis_MC2_155 QPLLPDLVEEEPFTGTVLHTARWDHSIPLAGKKIAVLGTGSTAAQLVPEL
TH_3452|M.thermoresistible__bu RPVMPDLVEEEPFTGTLMHSARWDHGIDLHGKRIAVLGTGSTASQLIPEL
MLBr_00065|M.leprae_Br4923 QGYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNIVVIGSGATAVTLVPAL
. * : : : * :*. :* . .:.*:*:*::. :: :
Mb0916|M.bovis_AF2122/97 AGVAGK-VTMFQRTAQWVLPWP--NPRYSKLARVFHRAFPCLGSLAYKAY
Rv0892|M.tuberculosis_H37Rv AGVAGK-VTMFQRTAQWVLPWP--NPRYSKLARVFHRAFPCLGSLAYKAY
MAB_4476c|M.abscessus_ATCC_199 VKTAAR-VKVFQRTPGWVLPRL--DFQHPDWAQRVFGSSPAVQNLARQAW
MUL_1053|M.ulcerans_Agy99 AKVADR-VYSIQRSPTWILPKP--DRPYSRWERWVFAHVPFAARLYRTRL
MMAR_0403|M.marinum_M AKVADR-VYSIQRSPTWILPKP--DRPYSRWERWVFAHVPFAARLYRTRL
MAV_5119|M.avium_104 AKVAER-VYSVQRSPTWILPKP--DRPYTRWERWAFAHLPLAKKLYRTRL
Mflv_4103|M.gilvum_PYR-GCK AKQAAA-VYSVQRSPTWVLPKP--DRPYTDREKWMFAHVPFAKKIYRTRL
Mvan_2243|M.vanbaalenii_PYR-1 AKQAAK-VYSVQRSPTWVLPKP--DREYTGREKWMFAHIPLAKKIYRTRL
MSMEG_2567|M.smegmatis_MC2_155 AKVADT-VYSVQRSPTWILPKP--DRPYTDRERWVFAHVPLAKKIYRTRL
TH_3452|M.thermoresistible__bu AKIADR-VYSVQRSPTWILPKP--DRPYSDRERWVFRHVPFAKRIYRTRL
MLBr_00065|M.leprae_Br4923 ANSGAKHVTMLQRSPTYIVSQPAKDKIAARLNRWLPDKYAYTAVRWKNIL
. . * .**:. :::. : . : .
Mb0916|M.bovis_AF2122/97 SLSFETFAVALSNPGLHRKLVGAVCRASLRR-VRDPRLRRALTPDYEPMC
Rv0892|M.tuberculosis_H37Rv SLSFETFAVALSNPGLHRKLVGAVCRASLRR-VRDPRLRRALTPDYEPMC
MAB_4476c|M.abscessus_ATCC_199 YWTHEAAAVGMVWDTPVTTLIQWIAKANLRRQISDPWVRRQLTPDFRAGC
MUL_1053|M.ulcerans_Agy99 WLRSESNISVIEHGSPKTKEFTELALRMLENTVSDPQLRRQLTPDHPMGC
MMAR_0403|M.marinum_M WLRSESNISVIEHGSPKTKEFTELALRMLENTVSDPQLRRQLTPDHPMGC
MAV_5119|M.avium_104 WLRSESNISVIEHGSEKTGQFTNIALGLLEASVPDEELRRKLTPDHPMGC
Mflv_4103|M.gilvum_PYR-GCK WLRSESNISVIEHGSDKTQEFKSIALRTLEATVSDDELRARLTPDHPLGC
Mvan_2243|M.vanbaalenii_PYR-1 WLRSESNISVIENGSDKTEEFKGIALRTLEATVADDELRAKLTPTHPLGC
MSMEG_2567|M.smegmatis_MC2_155 WLRSESNISVIEHGSDKTQEFRSIALNMLRSTVTDDELRERLTPDHPLGC
TH_3452|M.thermoresistible__bu WLRSEANISVIEDGSEKTEEFKAIALKMLEATVPDEEMRRRLTPDHPLGC
MLBr_00065|M.leprae_Br4923 RQSALYGACQKWPQRMRNILLGHVARRLPKGYDVQKHFGPHYNPWEQRLC
. :. . : . .* *
Mb0916|M.bovis_AF2122/97 KRLVMSGGFYRAIQRDDVELVTAGIDHVEHRGIVTDDGVLHEVDVIVLAT
Rv0892|M.tuberculosis_H37Rv KRLVMSGGFYRAIQRDDVELVTAGIDHVEHRGIVTDDGVLHEVDVIVLAT
MAB_4476c|M.abscessus_ATCC_199 KRMLMTSDYYAALEKDNCKLITWPIATLSPNGIRTADGIEHDVDCIVFAT
MUL_1053|M.ulcerans_Agy99 KRLVFSSEFLTALTRPNVELVTSPARYLRQRSLVTADGAEYDVDVVVCAT
MMAR_0403|M.marinum_M KRLVFSSEFLTALARPNVELVTSPARYLRQRSLVTADGAEYDVDVVVCAT
MAV_5119|M.avium_104 KRLVFSSDYLPALTRPNVEVLTSPARSLRRRSLVTEDGTEREVDLVVCAT
Mflv_4103|M.gilvum_PYR-GCK KRLVFATDYLKTLTEPHVDVVSSPARALRSRSLVTEDGTELDVDVVLCAT
Mvan_2243|M.vanbaalenii_PYR-1 KRLVFATDYLQTLTQPHVEVVSSPARSLRSRSLVTEDGTELDVDVVLCAT
MSMEG_2567|M.smegmatis_MC2_155 KRLVFSSDFIPTLTRPNVEVVSSPARALRSRSLVTEDGRELDVDIVACAT
TH_3452|M.thermoresistible__bu KRLVFSSDYLAALMRPNVEVVSSPARALRGDTLITEDGTERRVDVVVCAT
MLBr_00065|M.leprae_Br4923 --LVPDGDLFRAIRKGTVDMVTDAIDRFTSTGIRLKSGNELRADIIVTAT
:: :: . .::: . : .* .* : **
Mb0916|M.bovis_AF2122/97 GFDSHAFFRPMQLTGRDGIRIDDVWQDGPHAHQTVAIPGFPNFFMMLGPH
Rv0892|M.tuberculosis_H37Rv GFDSHAFFRPMQLTGRDGIRIDDVWQDGPHAHQTVAIPGFPNFFMMLGPH
MAB_4476c|M.abscessus_ATCC_199 GFDVCKAGTPFPIAGLDGRKLADEWSGGAYAYKSVNVSGYPNLFFTFGPN
MUL_1053|M.ulcerans_Agy99 GYAAADYLGQLEVLGEDGAGLHEVWRDGAHAYLGMAVPGFPNFFMLCGPN
MMAR_0403|M.marinum_M GYAAADYLGQLEVLGEDGAGLHEVWRDGAHAYLGMAVPGFPNFFMLYGPN
MAV_5119|M.avium_104 GYAAADYLGELDVTGEHGVTLREVWRDGAYAYLGMAVPGFPNFFMLYGPN
Mflv_4103|M.gilvum_PYR-GCK GYAAADYLGQIDVRGADDIPLSQTWRDGAFAYLGMSVPGYPNFFMLYGPN
Mvan_2243|M.vanbaalenii_PYR-1 GYAAADYLGQIEVRGADDALLSDTWRDGAFAYLGMAVPGYPNFFMLYGPN
MSMEG_2567|M.smegmatis_MC2_155 GYAAADYLGQIEVTGEGGIRLHDVWRDGAYAYLGMTVPGFPNFFMLYGPN
TH_3452|M.thermoresistible__bu GYAAADYLGQIEVVGERQRSLREVWRDGAYAYLGMTVPGFPNFFMLYGPN
MLBr_00065|M.leprae_Br4923 GLNLQLFGGAVATVDGQPVDLAQTMS-----YKGMMLSGLPNMIYTVG--
* . . : : : : :.* **:: *
Mb0916|M.bovis_AF2122/97 SPVGNFPLTAVAESQAEHIVQWIKRWRHGEFDTMEPKSAATEAYNTVLRA
Rv0892|M.tuberculosis_H37Rv SPVGNFPLTAVAESQAEHIVQWIKRWRHGEFDTMEPKSAATEAYNTVLRA
MAB_4476c|M.abscessus_ATCC_199 SGPGHNSALVYMEAQIDYIVQAIGIVRAKDLLTLDVRKDRQDRFNEDIQR
MUL_1053|M.ulcerans_Agy99 TNVGSNSVIFMLEAQARYIVAALAHLRRKSKTYIAVRPGVLAEFIAKVDR
MMAR_0403|M.marinum_M TNVGSNSVIFMLEAQARYIVAALAHLRRKSKTYIAVRPGVLAEFMAKVDR
MAV_5119|M.avium_104 TNVGSNSVIFVLEAQARYIVRALKYLRRHRRRYIAVRPAALADFVAKIDR
Mflv_4103|M.gilvum_PYR-GCK TNVGSNSVIFVLEAQARYIVRALKYLRRRNRSYIEVRSDVMKRYLDKIDS
Mvan_2243|M.vanbaalenii_PYR-1 TNVGSNSVIFMLEAQAHYIVRALKYMRRKNRSYIEVRSDVMTRFLERIDT
MSMEG_2567|M.smegmatis_MC2_155 TNVGSNSVIFVLEAQARYVVRALKHLRRRRKSYVAVKPEVMAQFIADIDR
TH_3452|M.thermoresistible__bu TNVGSNSVLFILEAQARYVVKALKRLRRRDTSYIAVRPDTAAAFLAKVDQ
MLBr_00065|M.leprae_Br4923 --YTNASWTLKADLVSEFFCRLLNYMNANDFDTVAVEYPGSDVEERPFMD
. : .. : . : . .
Mb0916|M.bovis_AF2122/97 AMPNTVWTTGCDSWYLNKDG-IPEVWPFAPAKHRAMLANLHPEEYDLRRY
Rv0892|M.tuberculosis_H37Rv AMPNTVWTTGCDSWYLNKDG-IPEVWPFAPAKHRAMLANLHPEEYDLRRY
MAB_4476c|M.abscessus_ATCC_199 RLGKTTWNSGCQSWYLTEDGKNTTMFPGFATQFARQLRTVELDDYSFTSG
MUL_1053|M.ulcerans_Agy99 WMTGTVWTTECSNYFRAPNGRVVTQWPRSARSFWGMTRRFKPADFSFQPA
MMAR_0403|M.marinum_M WMTGTVWTTECSNYFRAPNGRVVTQWPRSARSFWGMTRRFKPADFSFQPA
MAV_5119|M.avium_104 WMVGTVWTTQCSNYFRAPNGRVVTQWPRSARAFWSMTRRFRPADYRFQAP
Mflv_4103|M.gilvum_PYR-GCK WMQGTVWLTRCSNYFRAPNGRVVTQWPRSARDFWALTRWFRAGDYVFEAP
Mvan_2243|M.vanbaalenii_PYR-1 WMQGTVWLTRCSNYFRAPNGRVVTQWPRSARTFWGLTRRFNPGDYGFDAP
MSMEG_2567|M.smegmatis_MC2_155 WMQGTVWLTRCSSYFRAPNGRVVTQWPRSARALWAMTRRFRAADYLFSAP
TH_3452|M.thermoresistible__bu WMQGKVWSTQCNNYFRAPNGRVVTQWPRSARAFWAMTRRFRSADYLFEPA
MLBr_00065|M.leprae_Br4923 FTPG--YVLRSLDALPKQGSRTPWRLNQNYLRDIRLIRRGKVADEGLLFA
: . . .. . : :
Mb0916|M.bovis_AF2122/97 AAVRATSRPQSA--------------------------------
Rv0892|M.tuberculosis_H37Rv AAVRATSRPQSA--------------------------------
MAB_4476c|M.abscessus_ATCC_199 AAAASAAKPPVDASIG----------------------------
MUL_1053|M.ulcerans_Agy99 AVFAADGGDRNAGQRWPNPRPSIGWTPCCAPSRRRESTSPRSRS
MMAR_0403|M.marinum_M AVFAADGGDRNAGQR-----------------------------
MAV_5119|M.avium_104 AVRVPAPAS-EADAR-----------------------------
Mflv_4103|M.gilvum_PYR-GCK SA--RETISVGAQAEAER--------------------------
Mvan_2243|M.vanbaalenii_PYR-1 SS--RSRIRVGAQTSVKQP-------------------------
MSMEG_2567|M.smegmatis_MC2_155 VDGQAQVVEVAAHETVG---------------------------
TH_3452|M.thermoresistible__bu PD--MSEVSADARPVASR--------------------------
MLBr_00065|M.leprae_Br4923 KKTTPVTV------------------------------------