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MTTDTQIPALRAAELVKAYPGSDARAVDGLDLTIPQGIVYCLLGRNGAGKTTTIRMATTLLAPTRGELEV LGVPVDNTKELRPLIGVALQEVALDLWMSPVEQIRMSLAIAGWPKARRKAREDELVEQFGLSTYVNRKVG ALSGGMRRRVDVALAVAHNPQMLFLDEPSSGLDIEGKQEVWNAIRLLRSEGRTVVLTTHDMDEAVSLADE VGIVKSGRLVASGSTQEFTRSHGYAVEVSADSVIPEEAAGRLAEAGYALRRTDSGTLSGTLDSASAADLG ALSAELDRVGLGAASIEVRSTSLRDAFLEVTQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1689 | - | - | 100% (312) | daunorubicin resistance ABC transporter ATP-binding subunit DrrA |
| M. abscessus ATCC 19977 | MAB_2752 | - | 6e-32 | 32.42% (293) | ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_4215c | - | 1e-29 | 31.79% (302) | ABC transporter ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1493c | - | 1e-33 | 34.39% (314) | unidentified antibiotic-transport ATP-binding protein ABC |
| M. gilvum PYR-GCK | Mflv_1936 | - | 1e-45 | 37.79% (307) | daunorubicin resistance ABC transporter ATPase subunit |
| M. tuberculosis H37Rv | Rv1458c | - | 1e-33 | 34.39% (314) | unidentified antibiotic-transport ATP-binding protein ABC |
| M. leprae Br4923 | MLBr_02352 | - | 4e-35 | 31.80% (305) | putative antibiotic resistance efflux protein |
| M. marinum M | MMAR_0171 | - | 1e-136 | 79.61% (304) | ATP-binding protein ABC transporter |
| M. avium 104 | MAV_3250 | - | 6e-48 | 37.54% (309) | daunorubicin resistance ATP-binding protein DrrA |
| M. smegmatis MC2 155 | MSMEG_6766 | - | 1e-35 | 35.19% (287) | ABC transporter, ATP-binding protein, NodI family protein |
| M. thermoresistible (build 8) | TH_2788 | - | 9e-34 | 35.19% (287) | PUTATIVE ABC transporter ATP-binding protein |
| M. ulcerans Agy99 | MUL_4925 | - | 1e-136 | 79.28% (304) | ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_4796 | - | 2e-43 | 36.91% (317) | daunorubicin resistance ABC transporter ATPase subunit |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0171|M.marinum_M -MSSPESKTDNETGDSQPGTSALEAVDLVKSYPG-SDANAVDGLNLVIPR
MUL_4925|M.ulcerans_Agy99 -MSSPESKTDNETGDSQPGTSALEAVDLVKSYPG-SDANAVDGLNLVIPR
MAB_1689|M.abscessus_ATCC_1997 -----------MTTDTQ--IPALRAAELVKAYPG-SDARAVDGLDLTIPQ
Mb1493c|M.bovis_AF2122/97 -----------MNRAPDTPEVVLRLRGVCKRYG---SITAVSNLDLDVHD
Rv1458c|M.tuberculosis_H37Rv -----------MNRAPDTPEVVLRLRGVCKRYG---SITAVSNLDLDVHD
MSMEG_6766|M.smegmatis_MC2_155 -----------MS-------AAVEVRGLSKSYG---RRPAVRDLDLDVGY
Mflv_1936|M.gilvum_PYR-GCK ----------------MPFPPAIEALDLVKRFG---DQTAVAGVSFVVPP
Mvan_4796|M.vanbaalenii_PYR-1 MADKSVGPMSVCAYTVDAMESAIEAIDLVKRFGDTLDNPAVDGVSFAVPP
MLBr_02352|M.leprae_Br4923 ---------------MRNNDKAVMVRGVRKTYGK-GKIIALDDVSFDVDR
MAV_3250|M.avium_104 -----------------MSAPAIEVEGLTKKFG--GSTLALAGVDFSVPA
TH_2788|M.thermoresistible__bu -----------------MMAAMIELTALTKVFG---RTRAVDDLTCTVEP
: : * : *: .: :
MMAR_0171|M.marinum_M GVVYCLLGRNGAGKTTTIRMATTLLTPTSGQLEVLG-VPVDNTTQLRPLI
MUL_4925|M.ulcerans_Agy99 GVVYCLLGRNGAGKTTTIRMATTLLTPTSGQLEVLG-VPVDNTTQLRPLI
MAB_1689|M.abscessus_ATCC_1997 GIVYCLLGRNGAGKTTTIRMATTLLAPTRGELEVLG-VPVDNTKELRPLI
Mb1493c|M.bovis_AF2122/97 AEVMALLGPNGAGKTTTVEMCEGFVRPDAGSIEVLGLDPITDNARLRARI
Rv1458c|M.tuberculosis_H37Rv AEVMALLGPNGAGKTTTVEMCEGFVRPDAGSIEVLGLDPITDNARLRARI
MSMEG_6766|M.smegmatis_MC2_155 GEIFAILGPNGAGKTTTVEILEGNRRRDSGEVLVLGEDPGRAGRQWRARI
Mflv_1936|M.gilvum_PYR-GCK GTVLGLLGPNGAGKTTTVRMMTTLTEPTSGTARVAGFDVRTHPDEVRRHM
Mvan_4796|M.vanbaalenii_PYR-1 GTVLGLLGPNGAGKTTTVRMMTTLTEPTSGTARVAGYDVRAQPDDVRRHM
MLBr_02352|M.leprae_Br4923 GEVIGLLGPNGAGKTTMVDILSTLTRPDRGLATVAGYDVVSEPAGVRRSI
MAV_3250|M.avium_104 GTVCGLLGHNGAGKTTTINILSTLIRPTSGRARVAGYDVVRQPAEVRASI
TH_2788|M.thermoresistible__bu GVVTGFLGPNGAGKTTTMRLILGLDRPTSGTATIDGRRYRDLRDPLR-TV
. : :** ******* : : * : * * :
MMAR_0171|M.marinum_M GVALQEVALDLWMSPVEQIRMSLAMAGWPKSDRKRREGELVEQFGLGKYL
MUL_4925|M.ulcerans_Agy99 GVALQEVALDLWMSPVEQIRMSLAMAGWPKSDRKRREGELVEQFGLGKYL
MAB_1689|M.abscessus_ATCC_1997 GVALQEVALDLWMSPVEQIRMSLAIAGWPKARRKAREDELVEQFGLSTYV
Mb1493c|M.bovis_AF2122/97 GVMLQGGGGYPAARAGEMLDLVASYAAN-----PLDPHWLLDTLGLTEAA
Rv1458c|M.tuberculosis_H37Rv GVMLQGGGGYPAARAGEMLDLVASYAAN-----PLDPHWLLDTLGLTEAA
MSMEG_6766|M.smegmatis_MC2_155 GIVLQEVSDAGMLTVGETVQMFSACYGT-----ARAPADVLELVGLRHAS
Mflv_1936|M.gilvum_PYR-GCK GLTGQVATVDELLTGRENIRMIGGLYGIRRRDLKNLGDQLLHQFSLTDAA
Mvan_4796|M.vanbaalenii_PYR-1 GLTGQVATVDELLTGRENIRMIGGLYGIRRKDLDRLGDQLLHQFSLTDAA
MLBr_02352|M.leprae_Br4923 MVTGQQVAVDDQLSGEQNLILFGRLYGLSKSVARVRTQELLEQFDLLHAG
MAV_3250|M.avium_104 GMAGQFTGMDPMLTGRENLVLFGRLRGLNRRRAKARADELLEQFNLVDAA
TH_2788|M.thermoresistible__bu GALLDARAVHPARSARNHLRWLAAANRIP----QRRVDEVLELVGLTAVA
: : : ::. ..*
MMAR_0171|M.marinum_M NRKVGALSGGMRRRVDVALAVAHNPQMLFLDEPSSGLDIEGKQEVWNAIR
MUL_4925|M.ulcerans_Agy99 NRKVGALSGGMRRRVDVALAVAHNPQMLFLDEPSSGLDIEGKQEVWNAIR
MAB_1689|M.abscessus_ATCC_1997 NRKVGALSGGMRRRVDVALAVAHNPQMLFLDEPSSGLDIEGKQEVWNAIR
Mb1493c|M.bovis_AF2122/97 RTTYRRLSGGQQQRLALACALVGRPQLVFLDEPTAGMDAHARVLVWELID
Rv1458c|M.tuberculosis_H37Rv RTTYRRLSGGQQQRLALACALVGRPQLVFLDEPTAGMDAHARVLVWELID
MSMEG_6766|M.smegmatis_MC2_155 RSRVRTLSGGQRRRLDVALGIIGGPELVFLDEPTTGFDPEARQQFWELIR
Mflv_1936|M.gilvum_PYR-GCK DRPVRSYSGGMRRRLDLAVSLLASPPVLFLDEPTTGLDPRSRSELWDVLR
Mvan_4796|M.vanbaalenii_PYR-1 DRVVRSYSGGMRRRLDLAVSLLASPPVLFLDEPTTGLDPRSRSELWDVLR
MLBr_02352|M.leprae_Br4923 KRRVGTYSGGMRRRIDIACGLVVQPQVAFLDEPTTGLDPRSRQAIWDLVA
MAV_3250|M.avium_104 DRRLSTYSGGMYRRVDLASALVVPPKVLFLDEPTTGLDPRSRRDVWALVS
TH_2788|M.thermoresistible__bu ARPAGTLSLGMSQRLGIAGALLGDPPVLLFDEPVNGLDPEGIRWVRTLMR
* * :*: :* .: * : ::*** *:* .. . :
MMAR_0171|M.marinum_M LLRSEGRTVVLTTHDMDEAVSLADEVGIIKDGVLVAAGSTQEFTRSHGFA
MUL_4925|M.ulcerans_Agy99 LLRSEGRTVVLTTHDMDEAVLLADEVGIIKDGVLVAAGSTQEFTRSHGFA
MAB_1689|M.abscessus_ATCC_1997 LLRSEGRTVVLTTHDMDEAVSLADEVGIVKSGRLVASGSTQEFTRSHGYA
Mb1493c|M.bovis_AF2122/97 ALRRDGVTVVLTTHHLKEAEELADRLVIIDHGVTVAAGTPAELMRSGAKD
Rv1458c|M.tuberculosis_H37Rv ALRRDGVTVVLTTHHLKEAEELADRLVIIDHGVTVAAGTPAELMRSGAKD
MSMEG_6766|M.smegmatis_MC2_155 LLAADGTTIVLTTHYLEEAAALADRVAVIADGNVVAVDSPTRLTR-----
Mflv_1936|M.gilvum_PYR-GCK GLVAQGTTLLLTTQYLEEADQLADNIVVIDRGRIIAEGSPLHLKQQAGRA
Mvan_4796|M.vanbaalenii_PYR-1 GLVAQGTTLLLTTQYLEEADQLADNIVVIDRGHIIAEGSPLELKQQAGRA
MLBr_02352|M.leprae_Br4923 SFKQIGIATLLTTQYLEEADELSDRIILIDHGTVIAEGTASELKHRVGET
MAV_3250|M.avium_104 SLRVQGISVLLTTQYLEEADVLSDSIVVIDHGRVIASGTSEELKRAVGTS
TH_2788|M.thermoresistible__bu TMAAEGRTVLVSSHLLAEMANTADRLLVIGRGRLIASTSVAEFVGSTAAE
: * : ::::: : * :* : :: * :* : .:
MMAR_0171|M.marinum_M VDISAPQEITDDAVRQLAGAGYPMQ-----RKGSSAVTGSLDSASASEIG
MUL_4925|M.ulcerans_Agy99 VDISAPQEITDDAVRQLAGAGYPMQ-----RKGSSAVTGSLDSASASEIG
MAB_1689|M.abscessus_ATCC_1997 VEVSADSVIPEEAAGRLAEAGYALR-----RTDSGTLSGTLDSASAADLG
Mb1493c|M.bovis_AF2122/97 QLRFTAPPRLDLSLLASALPEGYQA-----TELTPGEYLVEGPVDPQVLA
Rv1458c|M.tuberculosis_H37Rv QLRFTAPPRLDLSLLASALPEGYQA-----TELTPGEYLVEGPVDPQVLA
MSMEG_6766|M.smegmatis_MC2_155 --------HVDTAATVRWMEGGHVH-----EERT--EFPTE---------
Mflv_1936|M.gilvum_PYR-GCK SLVVTVADAADLESARGLLARTGAE---VYVDAGARRLTATA-DGLDDMV
Mvan_4796|M.vanbaalenii_PYR-1 SLVVTVGDAADLEGARTLLGQTGAE---VFVDAGARRLTASA-DGLDDMI
MLBr_02352|M.leprae_Br4923 FCEIVPRDLKDLGTVVAALGSLLPERSRAMLTPTSDRITMPAPDGTQTLI
MAV_3250|M.avium_104 YCQVTPANPAELPQVAAALTGLEG----IEIDSDTGSVSVFAPDGVATLV
TH_2788|M.thermoresistible__bu RVRVRSPEMDTLRGLLADAG----------VEVRLEPDGAALTVRGAAPE
MMAR_0171|M.marinum_M SLATVLDRLGLAGANIEIRSTSLRDAFLEATQ---------------
MUL_4925|M.ulcerans_Agy99 SLATVLDRLGLAGANIEIRSTSLRDAFLEATQ---------------
MAB_1689|M.abscessus_ATCC_1997 ALSAELDRVGLGAASIEVRSTSLRDAFLEVTQ---------------
Mb1493c|M.bovis_AF2122/97 TVTAWCAQIDVLATDMRVEQRSLEDVFLDLTGRKLRQ----------
Rv1458c|M.tuberculosis_H37Rv TVTAWCAQIDVLATDMRVEQRSLEDVFLDLTGRKLRQ----------
MSMEG_6766|M.smegmatis_MC2_155 -LIRQRSRVGAELAQLTVTRPSLEDAYLHLIGRT-------------
Mflv_1936|M.gilvum_PYR-GCK KVAGWLRDSGITVDDIGLSRPSLDDVFLMLTGHRTDDTEEVGA----
Mvan_4796|M.vanbaalenii_PYR-1 RVAEWLRDSGIAVDDIGLSRPSLDDVFLTLTGHRTEDSEEIGA----
MLBr_02352|M.leprae_Br4923 EAARRIDEVSVELADIALRRPSLDDVFLSMTTDPSESLSHLAAGAMR
MAV_3250|M.avium_104 EVFRRVDALGLELADISLRKPSLDEAFLHLTER-TVARS--------
TH_2788|M.thermoresistible__bu VVGELAARNGITLHELSVQRASLEDAYLELTDAAVEYRAVPR-----
. .: : ** :.:*