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VHPHGGSQDGSLVHSAAANTAPEAVRVLVVDDHPIVHLGVERLVQGNPRVQMCTGARNVKSGVAVAAAER PHVVLLDLHLPDMALPEAAAALRGACLGVKLILFTGDSKPTVSQVAGLVGMDAVVHKDNACAVLVTAIEE VAAGRRFCDPVISTGNPLELSRREYQVLERLAIGETNAQIAQKLQLAPNTVKSYVQSLLAHLDARNRLDA VIKAQQAGML
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0132 | - | - | 100% (220) | two-component transcriptional regulatory protein |
| M. marinum M | MMAR_4782 | narL | 2e-19 | 31.60% (212) | nitrate/nitrite response regulator protein NarL |
| M. marinum M | MMAR_1516 | devR | 7e-18 | 32.20% (205) | two-component transcriptional regulatory protein DevR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0867c | narL | 4e-21 | 31.78% (214) | nitrate/nitrite response transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_0730 | - | 4e-21 | 32.08% (212) | two component LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0844c | narL | 1e-21 | 32.24% (214) | nitrate/nitrite response transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0060 | - | 5e-20 | 31.10% (209) | nitrate/nitrite response transcriptional regulatory protein |
| M. avium 104 | MAV_4109 | - | 7e-17 | 32.23% (211) | two component transcriptional regulatory protein devr |
| M. smegmatis MC2 155 | MSMEG_3944 | - | 6e-19 | 34.33% (201) | two component transcriptional regulatory protein devr |
| M. thermoresistible (build 8) | TH_2159 | - | 3e-16 | 31.34% (201) | TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR (PROBABLY |
| M. ulcerans Agy99 | MUL_0351 | narL | 8e-20 | 31.60% (212) | nitrate/nitrite response regulator protein NarL |
| M. vanbaalenii PYR-1 | Mvan_1427 | - | 1e-17 | 32.34% (201) | two component LuxR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3944|M.smegmatis_MC2_155 -----------------------MVTVFLVDDHELVRRGLIDLVRSDPDL
Mvan_1427|M.vanbaalenii_PYR-1 -----------------------MVRVFLVDDHEVVRRGLIDLLSTDPEL
MAV_4109|M.avium_104 -----------------------MVKVFLVDDHEVVRRGLCDLLSSDPDL
TH_2159|M.thermoresistible__bu -----------------------MVSVFLVDDHEVVRRGLIDLLDSDPDL
Mb0867c|M.bovis_AF2122/97 ----------------MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGSV
Rv0844c|M.tuberculosis_H37Rv ----------------MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGSV
MUL_0351|M.ulcerans_Agy99 ----------------MDVTKTEKVRVVVGDDHPLFREGVVRALSLSGSV
Mflv_0730|M.gilvum_PYR-GCK ----------------MTG-PGR-VRVVVGDDHPMFRDGVVRALQSSGAI
MAB_0060|M.abscessus_ATCC_1997 ----------------MQV-SGELVRVVVGDDHPLFREGVVRALTASGQI
MMAR_0132|M.marinum_M MHPHGGSQDGSLVHSAAANTAPEAVRVLVVDDHPIVHLGVERLVQGNPRV
* *.: *** :.: *: : . :
MSMEG_3944|M.smegmatis_MC2_155 DVIGEAGSVSEAMARIPALRPEVAVLDVRLPDGNGIELCRDLLSRLPDLR
Mvan_1427|M.vanbaalenii_PYR-1 DVVGEAGSVSEALTRIPAVAPEVAVLDVRLPDGNGIELCRDLLSRVPGLR
MAV_4109|M.avium_104 RIVGEAGTVAEAKARIPAARPDVAVLDVRLPDGNGIELCRDLLSEHPDLR
TH_2159|M.thermoresistible__bu EVVGEAGTVAQAMARIPAAQPDVAVLDVRLPDGNGVELCRDLLARMPDLR
Mb0867c|M.bovis_AF2122/97 NVVGEADDGAAALELIKAHLPDVALLDYRMPGMDGAQVPAAVRSYELPTR
Rv0844c|M.tuberculosis_H37Rv NVVGEADDGAAALELIKAHLPDVALLDYRMPGMDGAQVAAAVRSYELPTR
MUL_0351|M.ulcerans_Agy99 NVVGEADDGAAALELIETHLPDVALLDYRMPRMDGAQVAAAVRSNGLPTR
Mflv_0730|M.gilvum_PYR-GCK DVVAEADDGTAALAAIREHRPAVALLDYRMPGMDGAEVAAAVQRGALPTR
MAB_0060|M.abscessus_ATCC_1997 TVVAEAENGTGALELIREHRPDVALVDYRMPELDGTQVAAAVRRDELPTR
MMAR_0132|M.marinum_M QMCTGARNVKSGVAVAAAERPHVVLLDLHLPDMALPEAAAALRGACLGVK
: * . * *.::* ::* : : :
MSMEG_3944|M.smegmatis_MC2_155 CLMLTSFTSDEATLDAILAGASGFVIKDIKGMDLTHAIKEVAAGHSLLDN
Mvan_1427|M.vanbaalenii_PYR-1 CLMLTSFTSDEAMLDAILAGASGYVIKDIKGMELAEAIKDVGAGRSLLDN
MAV_4109|M.avium_104 CLMLTSFTSDEAMLEAILAGASGFVIKDIKGMELARAIKDVGAGKSLLDN
TH_2159|M.thermoresistible__bu CLMLTSYTSDQAMLDAILAGASGYVVKDIKGMELAQAIKDVGAGRSLLDN
Mb0867c|M.bovis_AF2122/97 VLLISAHDEPAIVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAP
Rv0844c|M.tuberculosis_H37Rv VLLISAHDEPAIVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAP
MUL_0351|M.ulcerans_Agy99 VLLISAHDESAIVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAP
Mflv_0730|M.gilvum_PYR-GCK VLLISAHDESAIVYRALADGAAGFLPKESTRNELITAVLDCAKGRDVVAP
MAB_0060|M.abscessus_ATCC_1997 VLLLSAHDDAAIVYRALEEGAAGFLSKESTRTELVGAVLDCARGRDVVAA
MMAR_0132|M.marinum_M LILFTGDSKPTVSQVAGLVGMDAVVHKDNACAVLVTAIEEVAAGRRFCDP
::::. . * * . : *: : *: : . *: .
MSMEG_3944|M.smegmatis_MC2_155 RAAAALMKRLRETASHSDPLTGLSDQERMLLELLGEGLTNKQIAERMFLA
Mvan_1427|M.vanbaalenii_PYR-1 RAAAALMSRLRDTAERADPLLGLSSQERVLLDLLGEGLTNKQIADRMFLA
MAV_4109|M.avium_104 RAAAALMAKLRGSAAQADPLSGLTEQERTLLGLLSEGLTNRQIAARMFLA
TH_2159|M.thermoresistible__bu RAAEALMAKLRGADHQPDPLAGLSDQERVLLSLIGEGLTNKQIAARMFLA
Mb0867c|M.bovis_AF2122/97 SLVGGLAGEIRQRAAPVA--PVLSAREREVLNRIACGQSIPAIAAELYVA
Rv0844c|M.tuberculosis_H37Rv SLVGGLAGEIRQRAAPVA--PVLSAREREVLNRIACGQSIPAIAAELYVA
MUL_0351|M.ulcerans_Agy99 SLVGGLAGEIRQRAAPMA--PVLSAREREVLHRIAKGQSIPAIAGELYVA
Mflv_0730|M.gilvum_PYR-GCK SLAAGLAGEIRRRAEPEG--PALSPREREVLVLIAAGSTIPAMARELFLA
MAB_0060|M.abscessus_ATCC_1997 SLTAGLAGEIRKRAQPAG--PSLSTREREVLRMIAAGQTVPAIARALFLA
MMAR_0132|M.marinum_M VISTGNP-------------LELSRREYQVLERLAIGETNAQIAQKLQLA
. *: :* :* :. * : :* : :*
MSMEG_3944|M.smegmatis_MC2_155 ERTVKNYVSRLLAKLGMERRTQAAVFISKLDH--GRHHDEQY---
Mvan_1427|M.vanbaalenii_PYR-1 EKTVKNYVSRLLAKLGMERRTQAAVFVSRLDR--AGR--------
MAV_4109|M.avium_104 EKTVKNYVSRLLAKLGMERRTQAAVFASKLNQQAGRPPTPPDWPG
TH_2159|M.thermoresistible__bu EKTVKNYVSRLLAKLGMERRTQAAVFVSKLD----RPIDPRG---
Mb0867c|M.bovis_AF2122/97 PSTVKTHVQRLYEKLGVSDRAAAVAEAMRQRLLD-----------
Rv0844c|M.tuberculosis_H37Rv PSTVKTHVQRLYEKLGVSDRAAAVAEAMRQRLLD-----------
MUL_0351|M.ulcerans_Agy99 PSTVKTHVQRLYEKLGVSDRAAAVAEAMRQGLLD-----------
Mflv_0730|M.gilvum_PYR-GCK PSTVKTHVQRLYEKLGVSDRGAAVAEAMRRKLLD-----------
MAB_0060|M.abscessus_ATCC_1997 PSTVKTHVQRLYEKLGVGDRAAAVAEAMRRGLLE-----------
MMAR_0132|M.marinum_M PNTVKSYVQSLLAHLDARNRLDAVIKAQQAGML------------
***.:*. * :*. * *. :