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TGPGRVRVVVGDDHPMFRDGVVRALQSSGAIDVVAEADDGTAALAAIREHRPAVALLDYRMPGMDGAEVA AAVQRGALPTRVLLISAHDESAIVYRALADGAAGFLPKESTRNELITAVLDCAKGRDVVAPSLAAGLAGE IRRRAEPEGPALSPREREVLVLIAAGSTIPAMARELFLAPSTVKTHVQRLYEKLGVSDRGAAVAEAMRRK LLD*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_0730 | - | - | 100% (214) | two component LuxR family transcriptional regulator |
M. gilvum PYR-GCK | Mflv_3579 | - | 6e-30 | 39.90% (203) | two component LuxR family transcriptional regulator |
M. gilvum PYR-GCK | Mflv_5014 | - | 3e-25 | 31.55% (206) | two component LuxR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0867c | narL | 2e-84 | 74.88% (211) | nitrate/nitrite response transcriptional regulatory protein |
M. tuberculosis H37Rv | Rv0844c | narL | 5e-85 | 75.36% (211) | nitrate/nitrite response transcriptional regulatory protein |
M. leprae Br4923 | MLBr_01286 | - | 6e-11 | 29.20% (113) | putative two-component response regulatory protein |
M. abscessus ATCC 19977 | MAB_0060 | - | 6e-87 | 77.40% (208) | nitrate/nitrite response transcriptional regulatory protein |
M. marinum M | MMAR_4782 | narL | 1e-83 | 74.30% (214) | nitrate/nitrite response regulator protein NarL |
M. avium 104 | MAV_0872 | - | 2e-70 | 73.63% (182) | DNA-binding response regulator, LuxR family protein |
M. smegmatis MC2 155 | MSMEG_0105 | - | 4e-89 | 80.38% (209) | DNA-binding response regulator, LuxR family protein |
M. thermoresistible (build 8) | TH_3563 | - | 4e-32 | 40.49% (205) | PUTATIVE DNA-binding response regulator, LuxR family protein |
M. ulcerans Agy99 | MUL_0351 | narL | 1e-83 | 74.30% (214) | nitrate/nitrite response regulator protein NarL |
M. vanbaalenii PYR-1 | Mvan_2836 | - | 2e-31 | 42.27% (194) | two component LuxR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0730|M.gilvum_PYR-GCK -------MTGPGRVRVVVGDDHPMFRDGVVRALQSSGAIDVVAEADDGTA MSMEG_0105|M.smegmatis_MC2_155 -----MLTRMSDKVRVVVGDDHPMFREGVVRALTSSGDIDVVAEADNGAD Mb0867c|M.bovis_AF2122/97 -----MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA Rv0844c|M.tuberculosis_H37Rv -----MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA MMAR_4782|M.marinum_M -----MDVTKTEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA MUL_0351|M.ulcerans_Agy99 -----MDVTKTEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA MAV_0872|M.avium_104 --------------------------------------MNVVGEAEDGSA MAB_0060|M.abscessus_ATCC_1997 -----MQVSG-ELVRVVVGDDHPLFREGVVRALTASGQITVVAEAENGTG TH_3563|M.thermoresistible__bu -------MGEPQQPTVMVVDDHPIWREAVARDLAEAG-LSVVATADGVAA Mvan_2836|M.vanbaalenii_PYR-1 ---------------MMVVDDHPIWRDAVARDLADDG-FDVVATADGVAS MLBr_01286|M.leprae_Br4923 MTGPTTDADAATPHRVLIAEDEALIRLDLAEMLRDEG-YDIVGEAADGQE :*. * . Mflv_0730|M.gilvum_PYR-GCK ALAAIREHRPAVALLDYRMPGMDGAEVAAAVQRGALPTRVLLISAHDESA MSMEG_0105|M.smegmatis_MC2_155 ALELIKVHRPAVALLDYRMPQLDGAQVAAAVVRDELPTRVLLVSAHDESA Mb0867c|M.bovis_AF2122/97 ALELIKAHLPDVALLDYRMPGMDGAQVPAAVRSYELPTRVLLISAHDEPA Rv0844c|M.tuberculosis_H37Rv ALELIKAHLPDVALLDYRMPGMDGAQVAAAVRSYELPTRVLLISAHDEPA MMAR_4782|M.marinum_M ALELIKTHLPDVALLDYRMPRMDGAQVAAAVRSNELPTRVLLISAHDESA MUL_0351|M.ulcerans_Agy99 ALELIETHLPDVALLDYRMPRMDGAQVAAAVRSNGLPTRVLLISAHDESA MAV_0872|M.avium_104 ALELIKSHQPDVALLDYRMPGMDGAQVAAAVRADGLATRVLLISAHDESA MAB_0060|M.abscessus_ATCC_1997 ALELIREHRPDVALVDYRMPELDGTQVAAAVRRDELPTRVLLLSAHDDAA TH_3563|M.thermoresistible__bu ARRRAAAVRPDVVLMDMRLPDGDGARATAEVRAVSPDSRVLVLSASEERD Mvan_2836|M.vanbaalenii_PYR-1 AKRRAAVVQPAVVLMDMRLADGDGAQATAEVLAVSPSSRVLVLSASDERD MLBr_01286|M.leprae_Br4923 AVELAERHKPDLVIMDVKMPRRDGIDAASEIASKRIAP-IVVLTAFSQRD * * :.::* ::. ** ..: : . :::::* .: Mflv_0730|M.gilvum_PYR-GCK IVYRALADGAAGFLPKESTRNELITAVLDCAKGRDVVAPSLAAGLAGEIR MSMEG_0105|M.smegmatis_MC2_155 IVYSALQQGAAGFLSKESTRSELVSAVLSCAKGRDVITPHLAAGLAGEIR Mb0867c|M.bovis_AF2122/97 IVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIR Rv0844c|M.tuberculosis_H37Rv IVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIR MMAR_4782|M.marinum_M IVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIR MUL_0351|M.ulcerans_Agy99 IVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIR MAV_0872|M.avium_104 IVYQALQQGAAGFVLKDSTRSEIVKAVLDCAQGRDVVAPALVGGLAAEIR MAB_0060|M.abscessus_ATCC_1997 IVYRALEEGAAGFLSKESTRTELVGAVLDCARGRDVVAASLTAGLAGEIR TH_3563|M.thermoresistible__bu DVLEAVKAGATGYLVKSASKTELVDAVHATAQGRAVFTPGLAGLVLGEYR Mvan_2836|M.vanbaalenii_PYR-1 DVLEAVKAGATGYLVKSASKQELGDAVRATAQGRAVFTPGLAGLVLGEFR MLBr_01286|M.leprae_Br4923 LVERARDAGAMAYLVKPFTISDLIPAIALAMSRFSELT-----ALEREVA * * ** .:: * : :: *: .: : * Mflv_0730|M.gilvum_PYR-GCK --RRAEPEG---PALSPREREVLVLIAAGSTIPAMARELFLAPSTVKTHV MSMEG_0105|M.smegmatis_MC2_155 --RRNEPDV---PVLSPREREVLNLIAQGRSIPAMAKELYLAPSTVKTHV Mb0867c|M.bovis_AF2122/97 --QRAAPVA---PVLSAREREVLNRIACGQSIPAIAAELYVAPSTVKTHV Rv0844c|M.tuberculosis_H37Rv --QRAAPVA---PVLSAREREVLNRIACGQSIPAIAAELYVAPSTVKTHV MMAR_4782|M.marinum_M --QRAAPMA---PVLSAREREVLHRIAKGQSIPAIAGELYVAPSTVKTHV MUL_0351|M.ulcerans_Agy99 --QRAAPMA---PVLSAREREVLHRIAKGQSIPAIAGELYVAPSTVKTHV MAV_0872|M.avium_104 --QRAEPTG---PVLSAREREVLHRIARGQSIPAIAGELYVAPSTVKTHV MAB_0060|M.abscessus_ATCC_1997 --KRAQPAG---PSLSTREREVLRMIAAGQTVPAIARALFLAPSTVKTHV TH_3563|M.thermoresistible__bu RISRQPGAGPDAPRLTERETEILRYVAKGLTAKQIAAQLSLSHRTVENHV Mvan_2836|M.vanbaalenii_PYR-1 RIERDSPAG---PTLTERETEILRHVAKGLTAKQIASRLSLSHRTVENHV MLBr_01286|M.leprae_Br4923 -------------TLADR-LETRKLVERAKGLLQVKQGMTEPEAFKWIQR *: * * : . : : . : Mflv_0730|M.gilvum_PYR-GCK QRLYEKLGVSDRGAAVAEAMRRKLLD MSMEG_0105|M.smegmatis_MC2_155 QRLYEKLGVSDRAAAVAEAMRRHLLD Mb0867c|M.bovis_AF2122/97 QRLYEKLGVSDRAAAVAEAMRQRLLD Rv0844c|M.tuberculosis_H37Rv QRLYEKLGVSDRAAAVAEAMRQRLLD MMAR_4782|M.marinum_M QRLYEKLGVSDRAAAVAEAMRQGLLD MUL_0351|M.ulcerans_Agy99 QRLYEKLGVSDRAAAVAEAMRQGLLD MAV_0872|M.avium_104 QRLYEKLGVSDRAAAVAEAMRQGLLS MAB_0060|M.abscessus_ATCC_1997 QRLYEKLGVGDRAAAVAEAMRRGLLE TH_3563|M.thermoresistible__bu QATFRKLQVANRVELARYAIEHGLDE Mvan_2836|M.vanbaalenii_PYR-1 QATFRKLQIGNRVELARYAIEHGLDE MLBr_01286|M.leprae_Br4923 AAMDRRTTMKRVAEVVLETLDTPKDT .: : . ::