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MTSAANNGTSRREELLNVAAKLFAARGYHGTRMDDVAEAVGLNKATVYHYYASKSLILYDIYKSAADFTV EALHDDPTSSARETIYHFTRRLMVGIANDLERAAVYFQEGPYIAEWFTEEQVEYIRHSEAQVYEHVRDVI DRGIASGEFYDCDSHVLALGYIGMVLGAYRWLRPHGRRTAKEIAVEFSTALLRGLIRDENIRVESPLGID VQAGSEEQR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0120 | - | - | 100% (219) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_0712 | - | 2e-19 | 31.77% (192) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6009 | - | 5e-12 | 21.76% (193) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0163 | - | 2e-87 | 75.74% (202) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0719 | - | 1e-103 | 85.10% (208) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0158 | - | 2e-87 | 75.74% (202) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00717 | - | 5e-08 | 35.82% (67) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4574c | - | 5e-74 | 63.29% (207) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0381 | - | 2e-87 | 75.00% (204) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5138 | - | 1e-86 | 74.76% (206) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0160 | - | 1e-94 | 83.42% (199) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. ulcerans Agy99 | MUL_4731 | - | 2e-87 | 75.00% (204) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0126 | - | 1e-106 | 85.92% (213) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0719|M.gilvum_PYR-GCK -----------------MSRREELLAVATKLFAARGYHGTRMDDVADAVG
Mvan_0126|M.vanbaalenii_PYR-1 -------MSESTT--NGMSRREELLAVATKLFAARGYHGTRMDDVADAVG
MSMEG_0120|M.smegmatis_MC2_155 -------MTSAAN--NGTSRREELLNVAAKLFAARGYHGTRMDDVAEAVG
TH_0160|M.thermoresistible__bu -----------------MTRREELLAVATRLFAARGYHGTRMDDVADAIG
Mb0163|M.bovis_AF2122/97 -------MPSDTS-PNGLSRREELLAVATKLFAARGYHGTRMDDVADVIG
Rv0158|M.tuberculosis_H37Rv -------MPSDTS-PNGLSRREELLAVATKLFAARGYHGTRMDDVADVIG
MMAR_0381|M.marinum_M -------MPSET----GLSRREELLAVATKLFAARGYHGTRMDDVADVIG
MUL_4731|M.ulcerans_Agy99 -------MPSET----GLSRREELLAVATKLFAARGYHGTRMDDVADVIG
MAV_5138|M.avium_104 -------MPADSSTPNGQTRREELLAVATKLFAARGYHGTRMDDVADVIG
MAB_4574c|M.abscessus_ATCC_199 MQPVPEASKAGSSSQRRAGRREELVAVASKLFAARGYHGTRMDDIADVAG
MLBr_00717|M.leprae_Br4923 -------MTTARRRLSPEDRRAELLALGAEVFGKRPYDEVRIDEIAERAG
** **: :.:.:*. * *. .*:*::*: *
Mflv_0719|M.gilvum_PYR-GCK LNKATVYHYYASKSLILYDIYKGAADFTVDALHDDP--TASARETIYHFT
Mvan_0126|M.vanbaalenii_PYR-1 LNKATVYHYYASKSLILYDIYKGAADFTVDALHDDP--TATARETIYHFT
MSMEG_0120|M.smegmatis_MC2_155 LNKATVYHYYASKSLILYDIYKSAADFTVEALHDDP--TSSARETIYHFT
TH_0160|M.thermoresistible__bu LNKATVYHYYASKSLILYDIYRRAADSTVAALHDDP--NASAREMIYEFT
Mb0163|M.bovis_AF2122/97 LNKATVYHYYASKSLILFDIYRQAAEGTLAAVHDDP--SWTAREALYQYT
Rv0158|M.tuberculosis_H37Rv LNKATVYHYYASKSLILFDIYRQAAEGTLAAVHDDP--SWTAREALYQYT
MMAR_0381|M.marinum_M LNKATVYHYYASKSLILFDIYRQAAEGTLGALHAEP--SWTAREALYQYT
MUL_4731|M.ulcerans_Agy99 LNKATVYHYYASKSLILFDIYRQAAEGTLGALHAEP--SWTAREALYQYT
MAV_5138|M.avium_104 LNKATVYHYYASKSLILYDIYQQAAERTLAAVHDDP--SMTAREALYQYT
MAB_4574c|M.abscessus_ATCC_199 LNKATVYHYFASKALILYEIYFKAAEETLACLQDDP--RWSARESLYQCT
MLBr_00717|M.leprae_Br4923 VSRALMYHYFPDKRAFFAAVVKDEADRLYAATNIPPPAGLTMFEEVRVGV
:.:* :***:..* :: : *: . : * : * : .
Mflv_0719|M.gilvum_PYR-GCK RRLLVGIASDIERAAVYFQEGPYISEWFTEEQVDYIREKEAQVYEHVRDV
Mvan_0126|M.vanbaalenii_PYR-1 RRLLVGIANDIERAAVYFQEGPYITEWFTEEQVEYIREKETQVYEHVRDV
MSMEG_0120|M.smegmatis_MC2_155 RRLMVGIANDLERAAVYFQEGPYIAEWFTEEQVEYIRHSEAQVYEHVRDV
TH_0160|M.thermoresistible__bu RRLLVGIAGDIERAAVYFQEAPYITEWFTEEQVAYIRESEAKVYEHVRDV
Mb0163|M.bovis_AF2122/97 VRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREKEQQVYEHVHGL
Rv0158|M.tuberculosis_H37Rv VRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREKEQQVYEHVHGL
MMAR_0381|M.marinum_M VRLLTGIADNPERAAVYFQEQPYIAEWFTPEQVAEVREKEAQVHEHVHGL
MUL_4731|M.ulcerans_Agy99 VRLLTGIADNPERAAVYFQEQPYIAEWFTPEQVAEVREKEAQVHEHVHGL
MAV_5138|M.avium_104 VRLLDQIAANPEGAAVYFQEQPYITEWFTKEQVAAVREKETQVYEHVHGL
MAB_4574c|M.abscessus_ATCC_199 SRMLALIFSNREQGAVYFQENPFLSEWLSPEQVAEIRTREDMVQERVQNI
MLBr_00717|M.leprae_Br4923 LAYMAYHKQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQMEHIMSRIGDV
: : * . . : : : . : .:: .:
Mflv_0719|M.gilvum_PYR-GCK IDRGIAS--GEFNDCDSHVLALGYIGMTLGSYRWLRPHGRRTAQEIAVEF
Mvan_0126|M.vanbaalenii_PYR-1 IDRGIAS--GEFYDCDSHVLALGYIGMTLGSYRWLRPHGRRTAQEIAVEF
MSMEG_0120|M.smegmatis_MC2_155 IDRGIAS--GEFYDCDSHVLALGYIGMVLGAYRWLRPHGRRTAKEIAVEF
TH_0160|M.thermoresistible__bu IDRGIAS--GEFYECDSHVLALGYIGMTLGSYRWLRPDGRRTAEEIAEEF
Mb0163|M.bovis_AF2122/97 IDRGIAS--GEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEF
Rv0158|M.tuberculosis_H37Rv IDRGIAS--GEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEF
MMAR_0381|M.marinum_M IDRGIAS--GEFYECDSHVVALGYIGMTLGSYRWLRPHGRRTAREIAAEF
MUL_4731|M.ulcerans_Agy99 IDRGIAS--GEFYECDSHVVALGYIGMTLGSYRWLRPHGRRTAREIAAEF
MAV_5138|M.avium_104 IDRGIAS--GEFYECDSHVLALGYIGMTLGAYRWLRPSGRRSAKEIAAEF
MAB_4574c|M.abscessus_ATCC_199 IERGIAS--GEFVECDSHVMALGYIGMVLGSYRWLNPSGRRSAQEIAVEF
MLBr_00717|M.leprae_Br4923 VSVVPESKLHPDIERDLRVIVHGWLAFTFEVCRQRIMDPSTDADRLADSC
:. * : * :*:. *::.:.: * * .:* .
Mflv_0719|M.gilvum_PYR-GCK SSALLRGLIRDETVRATSPLGVGIDVTAKQ-------
Mvan_0126|M.vanbaalenii_PYR-1 STALLRGLIRDETVRTLSPLGVGIDAPVKTRILEEPS
MSMEG_0120|M.smegmatis_MC2_155 STALLRGLIRDENIRVESPLGIDVQAGSEEQR-----
TH_0160|M.thermoresistible__bu STALLRGLIRDEKIRADFPHGTGESEAEPANPAG---
Mb0163|M.bovis_AF2122/97 STALLRGLIRDESIRNQSPLGTRKET-----------
Rv0158|M.tuberculosis_H37Rv STALLRGLIRDESIRNQSPLGTRKET-----------
MMAR_0381|M.marinum_M STALLRGLIRDESIRNQSPLGS---------------
MUL_4731|M.ulcerans_Agy99 STALLRGLIRDESIRNQSPLGS---------------
MAV_5138|M.avium_104 STALLRGLIRDEEIRTTSPLGP---------------
MAB_4574c|M.abscessus_ATCC_199 STTLLRGLIRDEATRINDPLGVASATSLDGAR-----
MLBr_00717|M.leprae_Br4923 AHALLDAIARVPEISKELADAMAIARQPPQ-------
: :** .: * . .