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MNGISVEHDGAVLRIRLDRPEKLNAVDTPMLEELSVHIRDAEADESVRAVLLTGAGRAFCSGGDLTGGDT AGAADAANRVVRAITSLPKPVIAGVHGAAVGFGCSLALACDLVVAAPASYFQLAFTRVGLMPDGGASALL PLLIGRARTSRMAMTAEKISAATAFEWGMISHITSADEYESVLTDVLRSVSGGPTLAFGWTKRALAAATL AELEPVQAIEAEGQLALVETADFREGARAFRERRTPNFRGH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2601 | - | - | 100% (251) | enoyl-CoA hydratase/isomerase |
| M. avium 104 | MAV_1884 | - | 5e-94 | 67.74% (248) | enoyl-CoA isomerase |
| M. avium 104 | MAV_1283 | - | 2e-55 | 42.13% (254) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1174c | echA10 | 5e-56 | 45.28% (254) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2125 | - | 1e-60 | 48.19% (249) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv1142c | echA10 | 5e-56 | 45.28% (254) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02118 | echA6 | 5e-29 | 35.10% (208) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_4570c | - | 9e-41 | 37.01% (254) | enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_4309 | echA10 | 7e-56 | 44.62% (251) | enoyl-CoA hydratase EchA10 |
| M. smegmatis MC2 155 | MSMEG_5185 | - | 2e-60 | 46.67% (255) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_2638 | - | 1e-59 | 45.31% (256) | PUTATIVE enoyl-CoA hydratase PaaB |
| M. ulcerans Agy99 | MUL_0985 | echA10 | 2e-56 | 44.62% (251) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_4579 | - | 2e-60 | 46.85% (254) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5185|M.smegmatis_MC2_155 -----MTSTDASAETVTRDYPSIDDVSVSLTDGVLAVTLNRPDSLNSLNR
TH_2638|M.thermoresistible__bu -----MSS-------VT--YPSIDDLRVALSDGVLTVTLNRPDSLNSLTA
Mflv_2125|M.gilvum_PYR-GCK -----MTATD--------AYQGIDHLTASLDGSVLTVTLNRPESLNSLTA
Mvan_4579|M.vanbaalenii_PYR-1 MKGTFMTTTDP----TTDAYEGIADLAVGLDDGVLTVTLNRPNSLNSLTA
Mb1174c|M.bovis_AF2122/97 -----MSNYR------IDTRTIVPGLAVTLADGVLSVTIDRPESLNSLTK
Rv1142c|M.tuberculosis_H37Rv -----MSNYR------IDTRTIVPGLAVTLADGVLSVTIDRPESLNSLTK
MMAR_4309|M.marinum_M -----MPDTR------IETLAPVAGLEVKLRGGVLSVTIDRPESLNSLTP
MUL_0985|M.ulcerans_Agy99 -----MPDTR------IETLAPVAGLEVKLRGGVLSVTIDRPESLNSLTP
MAB_4570c|M.abscessus_ATCC_199 -----MSLDE-----------SVGAPDVAVDGGIMRVTFTRPDRMNALNG
MAV_2601|M.avium_104 ----------------------MNGISVEHDGAVLRIRLDRPEKLNAVDT
MLBr_02118|M.leprae_Br4923 ------------------------MIGITQAEGVMTIELQRPERRNALNS
.:: : : **: *::
MSMEG_5185|M.smegmatis_MC2_155 DMLDAVADAMEVAATDP---AVRVVRLGG--AGRGFSSGAGISEEDQ--N
TH_2638|M.thermoresistible__bu PMLQTLAEAVELAASDP---RVKVIRLTG--AGRGFCAGAGISEDDQ--A
Mflv_2125|M.gilvum_PYR-GCK PMLETFAVTLERAATDP---RVRVVRIGG--AGRGFCSGAGISEEDH--A
Mvan_4579|M.vanbaalenii_PYR-1 PMLQAFAATLERAAGDP---RVRVVRIGG--AGRGFCSGAGISEEDH--A
Mb1174c|M.bovis_AF2122/97 PVLAGMADAIEGAATDP---RVKVVRLGG--AGRGFSSGGAISVDD----
Rv1142c|M.tuberculosis_H37Rv PVLAGMADAIEGAATDP---RVKVVRLGG--AGRGFSSGGAISVDD----
MMAR_4309|M.marinum_M EVMAGIADAMEAAATDS---RVRVVRLGG--TGRGFSSGAGMSAQD----
MUL_0985|M.ulcerans_Agy99 EVMAGIADAMEAAATDS---RVRVVRLGG--TGRGFSSGAGMSAQD----
MAB_4570c|M.abscessus_ATCC_199 PATSGLIEALESIPGRD---DVRVVVISGGAPGSAFSAGADVTELAAGSA
MAV_2601|M.avium_104 PMLEELSVHIRDAEADE---SVRAVLLTG--AGRAFCSGGDLTGGDT---
MLBr_02118|M.leprae_Br4923 QLIEKLREAVQKASSADSEVSTRVIVLTG--QGTVFCAGADLSGDAF---
. :. .:.: : * * *.:*. ::
MSMEG_5185|M.smegmatis_MC2_155 -AKG-HDAAAVLDAANRAVAAIVALPKPVVAVVHGPAAGVGVSLALACDI
TH_2638|M.thermoresistible__bu -ARESGGGNALLDGANRSVTAIVNCPKPVVAVVPGAAAGVGVSLALACDV
Mflv_2125|M.gilvum_PYR-GCK NPGAAGSPNDVLDAANRCIRAIANLPQPAVAVVQGAAAGVGVSLALACDV
Mvan_4579|M.vanbaalenii_PYR-1 NPGAAGPPTDVLDGANRCIRAIANLPQPSVAVVQGAAAGVGVSLALACDV
Mb1174c|M.bovis_AF2122/97 -VWASGPPTDTVAEANRTVRAIVALPQPVVAVVQGPTVGCGVSLALACDL
Rv1142c|M.tuberculosis_H37Rv -VWASGPPTDTVAEANRTVRAIVALPQPVVAVVQGPTVGCGVSLALACDL
MMAR_4309|M.marinum_M -MGR-KTSTSSLTEINRAVRAITALPHPVVAVVHGPAAGVGVSLALACDL
MUL_0985|M.ulcerans_Agy99 -MGR-KTSTSSLTEINRAVRAITALPHPVVAVVHGPAAGVGVSLALACDL
MAB_4570c|M.abscessus_ATCC_199 DLTPLQAAELTMDNAERLVRAVLNCPVPTIAEVTGVAAGIGASVGLACDL
MAV_2601|M.avium_104 --------AGAADAANRVVRAITSLPKPVIAGVHGAAVGFGCSLALACDL
MLBr_02118|M.leprae_Br4923 -------AADYPDRLIELHRVMDAVPMPVIGAINGPAIGAGLQLAMQCDL
. .: * * :. : * : * * .:.: **:
MSMEG_5185|M.smegmatis_MC2_155 VLASDQAFFLLAFTKIGLMPDGGASALVAAAIGRIRAMRLALLADRLTAT
TH_2638|M.thermoresistible__bu VLASEQAFFLLAFTKIGLMPDGGASALVAAAIGRIRAMRMALLAERISAA
Mflv_2125|M.gilvum_PYR-GCK VLASEKSFFMLAFTKIGLMPDGAASALIAAAVGRIRAMRMALLAERITAD
Mvan_4579|M.vanbaalenii_PYR-1 VIASEKAFFMLAFTKIGLMPDGGASALIAAAVGRIRAMRMALLAERISAR
Mb1174c|M.bovis_AF2122/97 VLASDNAFFMLAHTNVGLMPDGGASALVQAAIGRIRAMHMALLPDRVPAA
Rv1142c|M.tuberculosis_H37Rv VLASDNAFFMLAHTNVGLMPDGGASALVQAAIGRIRAMHMALLPDRVPAA
MMAR_4309|M.marinum_M VLASESAYFLLAFTKIGLMPDGGASALIAAAIGRIRAMRMALLPERLPAT
MUL_0985|M.ulcerans_Agy99 VLASESAYFLLAFTKIGLMPDGGASALIAAVIGRIRAMRMALLPERLPAT
MAB_4570c|M.abscessus_ATCC_199 IYAADTAFFLLAFANIGLMPDGGSSALVSASIGRVKANAMALLAQPLSAT
MAV_2601|M.avium_104 VVAAPASYFQLAFTRVGLMPDGGASALLPLLIGRARTSRMAMTAEKISAA
MLBr_02118|M.leprae_Br4923 RVVAPDAYFQFPTSKYGLALDNWSIRRLSSLVGHGRARAMLLTAEKLTAD
.: ::* :. :. ** *. : : :*: :: : : .: :.*
MSMEG_5185|M.smegmatis_MC2_155 DAYDWGLISAVYPADEFDAAVDKVLAKLRNGPAVALRKTKQAINEATLTE
TH_2638|M.thermoresistible__bu EAHQWGLVTGVYPADEFDAAVDKVISTLTNGPAVALRETKQAINAATLGE
Mflv_2125|M.gilvum_PYR-GCK EAYAWGLVSQVYPADSLEAEAASVIETLATGPAVALRLTKDAINGATLTE
Mvan_4579|M.vanbaalenii_PYR-1 EAYDWGLVSSVHPAEEFDAEVDKVIATLVAGPAVALRKTKDAINAATLTE
Mb1174c|M.bovis_AF2122/97 EALSWGLVSAVYPAADFDAEVDKLISRLLAGPALAIAKTKNAINAATLTE
Rv1142c|M.tuberculosis_H37Rv EALSWGLVSAVYPAADFDAEVDKLISRLLAGPALAIAKTKNAINAATLTE
MMAR_4309|M.marinum_M EALSYGLVSAVYPVADFQNEVDAVISRLLSGPAVAFAKTKDSINAATLTE
MUL_0985|M.ulcerans_Agy99 EALSYGLVSAVYPVADFQNEVDAVISRLLSGPAVAFAKTKNSINAATLTE
MAB_4570c|M.abscessus_ATCC_199 DAFAAGLVNEALPGDQLRERVDKTARRLAHGSRRAMQLTKEAMNAVSLKL
MAV_2601|M.avium_104 TAFEWGMISHITSADEYESVLTDVLRSVSGGPTLAFGWTKRALAAATLAE
MLBr_02118|M.leprae_Br4923 IALQTGMANRIGALADAQAWAAEVTG----LAPLAIQHAKRVLNDD--GS
* *: . . . . *: :* :
MSMEG_5185|M.smegmatis_MC2_155 LDDAIAREREGQLELLVANDFREGAQAFQQNRRPEFTDQ
TH_2638|M.thermoresistible__bu LPDAIKRETEGQVRLLGSNDFREGTQAFQQKRAPKFTDV
Mflv_2125|M.gilvum_PYR-GCK VENALERETKGQLRLLHSDDFREGTKAFQQRRAAKFTDV
Mvan_4579|M.vanbaalenii_PYR-1 LEAALERETAGQLVLLKSADFREGTHAFQQRRVAKFTDS
Mb1174c|M.bovis_AF2122/97 LAPTLLRELDGQALLLRTDDFAEGATAFQQRRTPMFTGR
Rv1142c|M.tuberculosis_H37Rv LAPTLLRELDGQALLLRTDDFAEGATAFQQRRTPMFTGR
MMAR_4309|M.marinum_M LDRTLDREFQGQSALLRSPDFAEGARAFQQRRTPTFTDS
MUL_0985|M.ulcerans_Agy99 LDRTLDREFQGQSALLRSPDFAEGARAFQQRRTPTFTDS
MAB_4570c|M.abscessus_ATCC_199 FDEAIARERDGQIELLISPDAHEGFAAFLEGRRPNFS--
MAV_2601|M.avium_104 LEPVQAIEAEGQLALVETADFREGARAFRERRTPNFRGH
MLBr_02118|M.leprae_Br4923 IEEAWPEHKKLFDKAWTSQDVIEAQVARVEKRPPKFQGA
. . . : * *. * : * . *