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VNPGISIEREGGILRLTLDRPDKLNAVDTPMLNELLGRLDESADDASVRAVLLTGAGRAFCSGGDLTGGD TEGAAQAANDVVRAITELPKPVVAGVHGPAVGVGCALALACDLVVATRAAYFQLAFSKLGLMLDGGASVL LPAAIGRARAARVAMTAEKITAATAFEWGLISYVVDDDAYETDLAELTSTLANGPTHSYRWIKRALSAAT LSDLESVQSLEADGQRLLVRTSDFAEGVRAFRERRPTEFRGE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1884 | - | - | 100% (252) | enoyl-CoA isomerase |
| M. avium 104 | MAV_2601 | - | 5e-94 | 67.74% (248) | enoyl-CoA hydratase/isomerase |
| M. avium 104 | MAV_1283 | - | 6e-53 | 40.16% (254) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1174c | echA10 | 2e-54 | 44.92% (256) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2125 | - | 7e-57 | 45.78% (249) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv1142c | echA10 | 2e-54 | 44.92% (256) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_01241 | - | 8e-29 | 34.40% (250) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_4570c | - | 1e-36 | 35.57% (253) | enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_4309 | echA10 | 1e-54 | 43.82% (251) | enoyl-CoA hydratase EchA10 |
| M. smegmatis MC2 155 | MSMEG_5185 | - | 2e-57 | 45.63% (252) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_2638 | - | 2e-55 | 46.34% (246) | PUTATIVE enoyl-CoA hydratase PaaB |
| M. ulcerans Agy99 | MUL_0985 | echA10 | 1e-54 | 43.43% (251) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_4579 | - | 2e-56 | 44.09% (254) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2125|M.gilvum_PYR-GCK -----MTATD--------AYQGIDHLTAS--LDGSVLTVTLNRPESLNSL
Mvan_4579|M.vanbaalenii_PYR-1 MKGTFMTTTDP----TTDAYEGIADLAVG--LDDGVLTVTLNRPNSLNSL
TH_2638|M.thermoresistible__bu -----MSSVT---------YPSIDDLRVA--LSDGVLTVTLNRPDSLNSL
MSMEG_5185|M.smegmatis_MC2_155 -----MTSTDASAETVTRDYPSIDDVSVS--LTDGVLAVTLNRPDSLNSL
Mb1174c|M.bovis_AF2122/97 -----MSNYR------IDTRTIVPGLAVT--LADGVLSVTIDRPESLNSL
Rv1142c|M.tuberculosis_H37Rv -----MSNYR------IDTRTIVPGLAVT--LADGVLSVTIDRPESLNSL
MMAR_4309|M.marinum_M -----MPDTR------IETLAPVAGLEVK--LRGGVLSVTIDRPESLNSL
MUL_0985|M.ulcerans_Agy99 -----MPDTR------IETLAPVAGLEVK--LRGGVLSVTIDRPESLNSL
MAB_4570c|M.abscessus_ATCC_199 -----MSLDE-----------SVGAPDVA--VDGGIMRVTFTRPDRMNAL
MAV_1884|M.avium_104 ---------------------MNPGISIE--REGGILRLTLDRPDKLNAV
MLBr_01241|M.leprae_Br4923 -----MSQTDASCTIAELPYRSVTDLVVLDFPRPEVALITLNRPGRMNSM
: :*: ** :*::
Mflv_2125|M.gilvum_PYR-GCK TAPMLETFAVTLERAATDPRVRVVRIGG--AGRGFCSGAGISEEDH----
Mvan_4579|M.vanbaalenii_PYR-1 TAPMLQAFAATLERAAGDPRVRVVRIGG--AGRGFCSGAGISEEDH----
TH_2638|M.thermoresistible__bu TAPMLQTLAEAVELAASDPRVKVIRLTG--AGRGFCAGAGISEDDQ----
MSMEG_5185|M.smegmatis_MC2_155 NRDMLDAVADAMEVAATDPAVRVVRLGG--AGRGFSSGAGISEEDQ----
Mb1174c|M.bovis_AF2122/97 TKPVLAGMADAIEGAATDPRVKVVRLGG--AGRGFSSGGAISVDD-----
Rv1142c|M.tuberculosis_H37Rv TKPVLAGMADAIEGAATDPRVKVVRLGG--AGRGFSSGGAISVDD-----
MMAR_4309|M.marinum_M TPEVMAGIADAMEAAATDSRVRVVRLGG--TGRGFSSGAGMSAQD-----
MUL_0985|M.ulcerans_Agy99 TPEVMAGIADAMEAAATDSRVRVVRLGG--TGRGFSSGAGMSAQD-----
MAB_4570c|M.abscessus_ATCC_199 NGPATSGLIEALESIPGRDDVRVVVISGGAPGSAFSAGADVTELAAG--S
MAV_1884|M.avium_104 DTPMLNELLGRLDESADDASVRAVLLTG--AGRAFCSGGDLTGGDT----
MLBr_01241|M.leprae_Br4923 ALDLMKSLKQVLKRITYDHSVRVVVLTG--AGRGFCSGADQKFTAPVPQV
. :. . *:.: : * .* .*.:*. .
Mflv_2125|M.gilvum_PYR-GCK ANPGAAGSPNDVLDAANRCIRAIANLPQPAVAVVQGAAAGVGVSLALACD
Mvan_4579|M.vanbaalenii_PYR-1 ANPGAAGPPTDVLDGANRCIRAIANLPQPSVAVVQGAAAGVGVSLALACD
TH_2638|M.thermoresistible__bu AARESGGG-NALLDGANRSVTAIVNCPKPVVAVVPGAAAGVGVSLALACD
MSMEG_5185|M.smegmatis_MC2_155 NAKG--HDAAAVLDAANRAVAAIVALPKPVVAVVHGPAAGVGVSLALACD
Mb1174c|M.bovis_AF2122/97 --VWASGPPTDTVAEANRTVRAIVALPQPVVAVVQGPTVGCGVSLALACD
Rv1142c|M.tuberculosis_H37Rv --VWASGPPTDTVAEANRTVRAIVALPQPVVAVVQGPTVGCGVSLALACD
MMAR_4309|M.marinum_M --MGR-KTSTSSLTEINRAVRAITALPHPVVAVVHGPAAGVGVSLALACD
MUL_0985|M.ulcerans_Agy99 --MGR-KTSTSSLTEINRAVRAITALPHPVVAVVHGPAAGVGVSLALACD
MAB_4570c|M.abscessus_ATCC_199 ADLTPLQAAELTMDNAERLVRAVLNCPVPTIAEVTGVAAGIGASVGLACD
MAV_1884|M.avium_104 ---------EGAAQAANDVVRAITELPKPVVAGVHGPAVGVGCALALACD
MLBr_01241|M.leprae_Br4923 EGLTQPVRALRAMELLEEVILALRRLHQPVIAAINGPAIGGGLCLALAAD
: : *: * :* : * : * * .:.**.*
Mflv_2125|M.gilvum_PYR-GCK VVLASEKSFFMLAFTKIGLMP-DGAASALIAAAVGRIRAMRMALLAERIT
Mvan_4579|M.vanbaalenii_PYR-1 VVIASEKAFFMLAFTKIGLMP-DGGASALIAAAVGRIRAMRMALLAERIS
TH_2638|M.thermoresistible__bu VVLASEQAFFLLAFTKIGLMP-DGGASALVAAAIGRIRAMRMALLAERIS
MSMEG_5185|M.smegmatis_MC2_155 IVLASDQAFFLLAFTKIGLMP-DGGASALVAAAIGRIRAMRLALLADRLT
Mb1174c|M.bovis_AF2122/97 LVLASDNAFFMLAHTNVGLMP-DGGASALVQAAIGRIRAMHMALLPDRVP
Rv1142c|M.tuberculosis_H37Rv LVLASDNAFFMLAHTNVGLMP-DGGASALVQAAIGRIRAMHMALLPDRVP
MMAR_4309|M.marinum_M LVLASESAYFLLAFTKIGLMP-DGGASALIAAAIGRIRAMRMALLPERLP
MUL_0985|M.ulcerans_Agy99 LVLASESAYFLLAFTKIGLMP-DGGASALIAAVIGRIRAMRMALLPERLP
MAB_4570c|M.abscessus_ATCC_199 LIYAADTAFFLLAFANIGLMP-DGGSSALVSASIGRVKANAMALLAQPLS
MAV_1884|M.avium_104 LVVATRAAYFQLAFSKLGLML-DGGASVLLPAAIGRARAARVAMTAEKIT
MLBr_01241|M.leprae_Br4923 VRVASTRAYFRAAGINNGLSASELGLSYLLPRAVGSSRAFEIMLSGRDVG
: *: ::* * : ** : . * *: :* :* : : :
Mflv_2125|M.gilvum_PYR-GCK ADEAYAWGLVSQVYPADSLEAEAASVIETLATGPAVALRLTKDAIN-GAT
Mvan_4579|M.vanbaalenii_PYR-1 AREAYDWGLVSSVHPAEEFDAEVDKVIATLVAGPAVALRKTKDAIN-AAT
TH_2638|M.thermoresistible__bu AAEAHQWGLVTGVYPADEFDAAVDKVISTLTNGPAVALRETKQAIN-AAT
MSMEG_5185|M.smegmatis_MC2_155 ATDAYDWGLISAVYPADEFDAAVDKVLAKLRNGPAVALRKTKQAIN-EAT
Mb1174c|M.bovis_AF2122/97 AAEALSWGLVSAVYPAADFDAEVDKLISRLLAGPALAIAKTKNAIN-AAT
Rv1142c|M.tuberculosis_H37Rv AAEALSWGLVSAVYPAADFDAEVDKLISRLLAGPALAIAKTKNAIN-AAT
MMAR_4309|M.marinum_M ATEALSYGLVSAVYPVADFQNEVDAVISRLLSGPAVAFAKTKDSIN-AAT
MUL_0985|M.ulcerans_Agy99 ATEALSYGLVSAVYPVADFQNEVDAVISRLLSGPAVAFAKTKNSIN-AAT
MAB_4570c|M.abscessus_ATCC_199 ATDAFAAGLVNEALPGDQLRERVDKTARRLAHGSRRAMQLTKEAMN-AVS
MAV_1884|M.avium_104 AATAFEWGLISYVVDDDAYETDLAELTSTLANGPTHSYRWIKRALS-AAT
MLBr_01241|M.leprae_Br4923 AEEAEQIGLVSYRVSDDRLLDTCYSIAARMATFSRSGTELTKRALWGGLD
* * **:. : . . * ::
Mflv_2125|M.gilvum_PYR-GCK LTEVENALERETKGQL-RLLHSDDFREGTKAFQQRRAAKFTDV-------
Mvan_4579|M.vanbaalenii_PYR-1 LTELEAALERETAGQL-VLLKSADFREGTHAFQQRRVAKFTDS-------
TH_2638|M.thermoresistible__bu LGELPDAIKRETEGQV-RLLGSNDFREGTQAFQQKRAPKFTDV-------
MSMEG_5185|M.smegmatis_MC2_155 LTELDDAIAREREGQL-ELLVANDFREGAQAFQQNRRPEFTDQ-------
Mb1174c|M.bovis_AF2122/97 LTELAPTLLRELDGQA-LLLRTDDFAEGATAFQQRRTPMFTGR-------
Rv1142c|M.tuberculosis_H37Rv LTELAPTLLRELDGQA-LLLRTDDFAEGATAFQQRRTPMFTGR-------
MMAR_4309|M.marinum_M LTELDRTLDREFQGQS-ALLRSPDFAEGARAFQQRRTPTFTDS-------
MUL_0985|M.ulcerans_Agy99 LTELDRTLDREFQGQS-ALLRSPDFAEGARAFQQRRTPTFTDS-------
MAB_4570c|M.abscessus_ATCC_199 LKLFDEAIARERDGQI-ELLISPDAHEGFAAFLEGRRPNFS---------
MAV_1884|M.avium_104 LSDLESVQSLEADGQR-LLVRTSDFAEGVRAFRERRPTEFRGE-------
MLBr_01241|M.leprae_Br4923 AASLDKHMQSESLAQLFIALHTSNFEEAAAPCTEKRPTVLVDARGCATSP
. * .* : : : *. . : * . :
Mflv_2125|M.gilvum_PYR-GCK -
Mvan_4579|M.vanbaalenii_PYR-1 -
TH_2638|M.thermoresistible__bu -
MSMEG_5185|M.smegmatis_MC2_155 -
Mb1174c|M.bovis_AF2122/97 -
Rv1142c|M.tuberculosis_H37Rv -
MMAR_4309|M.marinum_M -
MUL_0985|M.ulcerans_Agy99 -
MAB_4570c|M.abscessus_ATCC_199 -
MAV_1884|M.avium_104 -
MLBr_01241|M.leprae_Br4923 G