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MAPLACDPTALDHAGATVVAAGESLGSVISTLTAALAGTSGMAGDDPVGAALGRRYDGAAAKLIQAMADT RNGLCSIGDGVRMSAHNYAVAEAMSDLAGRASALPAPQVTGPLTVGAPPSAVGHGSGAPAGWGWVAPSIG MIWPTGDSAKLRAAAAAWATAGANFMAAETAAGGGTMAAIGAQQIPEGAAINKALADASSATADVARQCQ TIAAQLNSYAAKVDQVHAAILDLLSRICDPLTGIKEVWDLLTDEDEDEIKKIADDIRTVVDNFGREADTL GGQIEATVSAVAAATENMSHWAGKEWDHFLHGTPVGRALNQVGQAFKGVGEEGWGFLKGLYEVSPNRMLL DPVGYGKTMAGMVEGAGTLVGLGPDGVPGAFDAWKALGKDVTHWDEWGSNPAEALGKSTFDVATLALPGG PLSKLGKFGHSAADALKGLKKPPGVPKPPEVKPPAAPKAPDSGQPAPSGKPGPVAPSGKPAPGPADGPLP HSPTESKPPAGGTPPAAEPPKPTAAPHSGEPKPIATPPESVGKPVTPAPAEGAPAQPHEPVSARVPPTVP AADTPAPSAPAASMSAASGPPMPPTPSLPEPASLPSGPSGDLPAETPPTAGIPHSGEPSAPSSVPPHFPD TPTHGLGDGGAHGPPESDPKNANGHGPHDASLDSGSDHHLPLHPLDSDDLAALAHYTGPGYQELNFALRE GALDVSQQARVDALQKALEKLPVYEGAVVRGTNLPADVLEQYRPGEVITEAAFTSTSTDHTVAQSSAFAG NTEFRIWSTTGRDVSSVSMYPDEKEILFPAGSKFYVVSKTVDPQTGRTIIEMIER
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_4644 | - | - | 100% (825) | hypothetical protein MAV_4644 |
M. avium 104 | MAV_2415 | - | 5e-74 | 31.15% (870) | hypothetical protein MAV_2415 |
M. avium 104 | MAV_2859 | - | 9e-15 | 36.20% (163) | ModD protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3933c | - | 0.0 | 52.33% (665) | hypothetical protein Mb3933c |
M. gilvum PYR-GCK | Mflv_3843 | - | 5e-19 | 30.49% (246) | hypothetical protein Mflv_3843 |
M. tuberculosis H37Rv | Rv3903c | - | 0.0 | 52.33% (665) | hypothetical protein Rv3903c |
M. leprae Br4923 | MLBr_00048 | - | 2e-10 | 34.72% (144) | hypothetical protein MLBr_00048 |
M. abscessus ATCC 19977 | MAB_3131c | - | 6e-17 | 31.30% (246) | translation initiation factor IF-2 (InfB) |
M. marinum M | MMAR_5464 | - | 0.0 | 51.86% (833) | ADP-ribosyltransferse |
M. smegmatis MC2 155 | MSMEG_1870 | - | 6e-57 | 29.30% (727) | hypothetical protein MSMEG_1870 |
M. thermoresistible (build 8) | TH_3868 | - | 2e-18 | 25.15% (342) | PUTATIVE putative conserved hypothetical protein |
M. ulcerans Agy99 | MUL_2318 | - | 3e-79 | 31.68% (726) | hypothetical protein MUL_2318 |
M. vanbaalenii PYR-1 | Mvan_2552 | - | 3e-18 | 29.25% (335) | hypothetical protein Mvan_2552 |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3843|M.gilvum_PYR-GCK ----------MSRTKKSIVVVMMGSAGLFLSAPLLGPAANATPTRGGVPC Mvan_2552|M.vanbaalenii_PYR-1 ----------MSRTKKSIVVVMMGSAGLFLSAPLLGPSANATPTRGGVPC MAV_4644|M.avium_104 ------------MAPLACDPTALDHAGATVVAAGESLGSVISTLTAALAG MMAR_5464|M.marinum_M ------------MAPLAVDPAALDGAGAAVVAAGEGLEPVIASLSAVLAG Mb3933c|M.bovis_AF2122/97 ------------MAPLAVDPAALDSAGGAVVAAGAGLGAVISSLTAALAG Rv3903c|M.tuberculosis_H37Rv ------------MAPLAVDPAALDSAGGAVVAAGAGLGAVISSLTAALAG MSMEG_1870|M.smegmatis_MC2_155 MPSNSGGGGGVSGIRIEVDPQVLIRAGESMLSLGNQLDMLMGALGPMLS- TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 ------MGKNPGVAPLSVDPEALSGAGSAVAAAGDALAAALSSLT---TG MLBr_00048|M.leprae_Br4923 ---------------MAADYDKLFRLDDGAYASPDQAAEQLFDDAPLYPP MAB_3131c|M.abscessus_ATCC_199 ---------MAGKARVHELAKELGVTSKEVLARLSDQGEFVKSASSTVEA Mflv_3843|M.gilvum_PYR-GCK VGILQQIVTRPGEIPQALTDTARSFTEPPKPAPPVVRPPASSSSSAGTPP Mvan_2552|M.vanbaalenii_PYR-1 VGILQQVISRPGDIPQALTETARSFTNPGQPAPPVVRPPASSSSSVGTPP MAV_4644|M.avium_104 TSGMAGDDPVGAALGRRYDGAAAKLIQAMADTRNGLCSIGDGVRMSAHNY MMAR_5464|M.marinum_M CAGMAGDDPVGAAVGRGYDRAAAKVFSAMAATRNGLCSIGDGVRMSAHNY Mb3933c|M.bovis_AF2122/97 CAGMAGDDPAGAVFGRSYDGSAAALVQAMSVARNGLCNLGDGVRMSAHNY Rv3903c|M.tuberculosis_H37Rv CAGMAGDDPAGAVFGRSYDGSAAALVQAMSVARNGLCNLGDGVRMSAHNY MSMEG_1870|M.smegmatis_MC2_155 SGIASGIDLAGLAMALDYGDLTQKFSNTLANGANTFKTVGLRLQASGHNY TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 FSANTGQDTAGEVFGLAYQDAAESLVKAAGAGINALRHNGAKIQLSASNY MLBr_00048|M.leprae_Br4923 PIIPTCTTTPNGEVASPMPDWSEQLPPNPPAAS---KSPLPPMPIGSSVQ MAB_3131c|M.abscessus_ATCC_199 PVARRLRESFGGGDKPAPAASNGAAAEAAAPPKKAGPKPGAPKPAPKKVA Mflv_3843|M.gilvum_PYR-GCK VPGRPPASVVTPSSGATPPVPPSPGTPASTSTRGGTPPVPPAPPAPAGTP Mvan_2552|M.vanbaalenii_PYR-1 VPPTPPGSVVRPSSGATPPVPPTPGTPASTTTGVGTPPVPPTPPGSTVRP MAV_4644|M.avium_104 AVAEAMSDLAGRASALPAP-QVTGPLTVGAPPSAVGHGSGAPAGWGWVAP MMAR_5464|M.marinum_M SLAEAMSDVTRRAAALPAP-TLTTCIVAASAPSAVGTADSAPAGWGWIAP Mb3933c|M.bovis_AF2122/97 SLAEAMSDVAGRAAPLPAP-PPSGCVGVGAPPSAVGGGGGAPKGWGWVAP Rv3903c|M.tuberculosis_H37Rv SLAEAMSDVAGRAAPLPAP-PPSGCVGVGAPPSAVGGGGGAPKGWGWVAP MSMEG_1870|M.smegmatis_MC2_155 ANADAVSTIGGGAPTGGVKGKFDETKPVDARDSPSLSVVPPPPAWYLVGS TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 SAAEAASTLGGGAGVLPAP-SEPAQFTAPGAPGTLGSGVLAPALWSVVEA MLBr_00048|M.leprae_Br4923 PPPASSESPRAPMPVSAPPRSPAASLMPISEPPQWPPAEAPEHQFAKAEP MAB_3131c|M.abscessus_ATCC_199 EPVVEAPVAPEPPAAPAAPAAPAPKPSPAARPAAAEAAAPAPAPAPAPRP Mflv_3843|M.gilvum_PYR-GCK ASGATPPAPPVPGVPAVTSTGGGTPPVPPVPGAPVGAPVANPGLPTPPVP Mvan_2552|M.vanbaalenii_PYR-1 AAGATPPAPPVPGVPAGTPIGGGTPPLPPVPGAPAGTPVANVAPPSPPVP MAV_4644|M.avium_104 SIG-MIWPTGDSAKLRAAAAAWATAGANFMAAETAAGGGTMAAIGAQQIP MMAR_5464|M.marinum_M YIG-MIWPTGNLSKLRTAASEWTAEGTKFALVETQLTAGPLGAIRSQQLP Mb3933c|M.bovis_AF2122/97 YIG-MIWPNGDSTKLRAAAVAWRSAGTQFALTEIQSTAGPMGVIRAQQLP Rv3903c|M.tuberculosis_H37Rv YIG-MIWPNGDSTKLRAAAVAWRSAGTQFALTEIQSTAGPMGVIRAQQLP MSMEG_1870|M.smegmatis_MC2_155 FLGPTAWPSGNPAMLRLTAAQWENLATGFSAVSNQVSG-SSTAVSTQKIP TH_3868|M.thermoresistible__bu -------------MLRLTVAQWRNFAHGFAVFEPQLAP-VLAVVSAQNTP MUL_2318|M.ulcerans_Agy99 FVG-DLWPNGDVAGLHAAAGHWRDFAAALNGVQGALNS-PKSVVAGQDIP MLBr_00048|M.leprae_Br4923 PSVPIPINEPSPAKPATPMPMTPIDGSQRTPVTSPEPSLAEFEAQPPATP MAB_3131c|M.abscessus_ATCC_199 GATPGPKP-GAPRVPRVGNNPFSSAQPAERPAPRPQAPRPGAPRPGGASP * Mflv_3843|M.gilvum_PYR-GCK GAPVFGDGGAVLPPLPPAPAGPAGGPAGLVAPPAPPVPGG-PAAVPAGVA Mvan_2552|M.vanbaalenii_PYR-1 GVPVIGDGGAALPPLPPVPGGPAAVPAGVVTPPAPPIPGG-PAAMPAGVA MAV_4644|M.avium_104 EGAAINKALADASSATADVARQCQTIAAQLNSYAAKVDQV-HAAILD-LL MMAR_5464|M.marinum_M ESGLIERAFTDAYVSTTSVVGQCQTIAAQLDRYADQIDEV-HAAILD-LL Mb3933c|M.bovis_AF2122/97 EAGLIESAFADAYASTTAVVGQCHQLAAQLDAYAARIDAV-HAAVLD-LL Rv3903c|M.tuberculosis_H37Rv EAGLIESAFADAYASTTAVVGQCHQLAAQLDAYAARIDAV-HAAVLD-LL MSMEG_1870|M.smegmatis_MC2_155 EASQIAQAHADLADGVADLANQATNLAETLNTFADNVQET-QDAIRR-LL TH_3868|M.thermoresistible__bu ETPAIVSGLDELARGISALTDASVEVAREVEDFAATVQGT-QDAIRR-LV MUL_2318|M.ulcerans_Agy99 EGVQIQQVLSAIGSDLAGVGAQCRKLAGALDDFADEVADT-QDAIRD-LL MLBr_00048|M.leprae_Br4923 KPSLLPRPMSSPPEAPRPSANQHSRHARRGHHHRDETQQANPASATEPMI MAB_3131c|M.abscessus_ATCC_199 SNMPPRPSPGSMGPRPPRPGGGPRPGGGPRPGGAGRPGGGGGGNYRGGGT . Mflv_3843|M.gilvum_PYR-GCK LPPAPPGAPGAPVFGEAGAAPSGAAAPVAPAAGSGGAGGAGGGSGIG-GP Mvan_2552|M.vanbaalenii_PYR-1 APPAP-APPGAPIFGEAGAVPPPGVGGAPLDGASGVAAPGGPGGGAG-AP MAV_4644|M.avium_104 SRICDPLTGIKEVWDLLTDEDEDEIKKIADDIRTVVDNFGREADTLG-GQ MMAR_5464|M.marinum_M ARICDPLTGIKEVWEVLTGEDEDEIERIAHEIAAVVDHFAAEANALS-AQ Mb3933c|M.bovis_AF2122/97 ARICDPLTGIKEVWEFLTDQDEDEIQRIAHDIAVVVDQFSGEVDALA-AE Rv3903c|M.tuberculosis_H37Rv ARICDPLTGIKEVWEFLTDQDEDEIQRIAHDIAVVVDQFSGEVDALA-AE MSMEG_1870|M.smegmatis_MC2_155 DRVASIDGIINTVKGIFTGDALDIIKEVVEDIRTLLGNFQRQVKAVG-AL TH_3868|M.thermoresistible__bu GRVS-ISGLFHTVKGILTGDGKDILREVARDVRTVLDNFQRQVKGVI-GL MUL_2318|M.ulcerans_Agy99 DRFGSVSGLWNQVVAIFEGDALDEIKEIAEDIRAVLSNLGRQARAQQ-QL MLBr_00048|M.leprae_Br4923 APRARTAELRQAPHAAAEPAPTQHLTRPDGLVSHRTALHDSTATSAI-GV MAB_3131c|M.abscessus_ATCC_199 GTGAPAGGPPGAGGGFRGRPGGGGGGGRPGQRGGAAGAFGRPGGAPKRGR Mflv_3843|M.gilvum_PYR-GCK GGGGAPVEGTGGAVPAGAPLAAAGGEVPPPAPPIPGAPVIGEAGVVPPPA Mvan_2552|M.vanbaalenii_PYR-1 GAPVAAAAGNAGPPAPGAPVGDQAGVVAPPAPPAPGAPVGDQAGLVAPPG MAV_4644|M.avium_104 IEATVSAVAAATENMSHWAGKEWDHFLH-------GTPVGRALNQVGQAF MMAR_5464|M.marinum_M FNAALVHADTVLDTMARHAAREWDQFLH-------GNPVGAIVDFAGQRL Mb3933c|M.bovis_AF2122/97 ITAVVSHAEAVITAMADHAGKQWDRFLH-------SNPVGVVIDGTGQQL Rv3903c|M.tuberculosis_H37Rv ITAVVSHAEAVITAMADHAGKQWDRFLH-------SNPVGVVIDGTGQQL MSMEG_1870|M.smegmatis_MC2_155 LEELKNALNDTVTKFQKWADKNLREILG-------DQVGGAISDIIKFQT TH_3868|M.thermoresistible__bu LEELATLIGDAATAFQKWLRPNLVAVFG-------EQVGGAMADRIELRT MUL_2318|M.ulcerans_Agy99 MQQGMQAIDGLVVGMQRYVRGQLTQLLG----QDVGNPVATVFDTYTNTQ MLBr_00048|M.leprae_Br4923 QTGRSTGAKKPSKVVAKRGWRHWVHTVT----------------RINLGL MAB_3131c|M.abscessus_ATCC_199 KSKRAKRAEYENMQAPVVGGVRLPHGNGEVIRLARGASLSDFAEKIDANP Mflv_3843|M.gilvum_PYR-GCK PPAPAPPAGGLGGAVPPPVP-GAPGVPVVDEAGVVTPPAPGGPGVPTGGE Mvan_2552|M.vanbaalenii_PYR-1 PPAPGVPVVDQAGVVAPPGP-PAPGVPVVDEAGVVTPPGPGAPGVPVVGE MAV_4644|M.avium_104 KGVGEEGWGFLKGLYEVSPN-RMLLDPVGYGKTMAGMVEGAGTLVGLGPD MMAR_5464|M.marinum_M KGLGEAAWGLAETALTYNQI-RALLDPLGYARDVGSMAQGMAPLVGLGDD Mb3933c|M.bovis_AF2122/97 KGFGEEAFGMAKDSWDLGPL-RASIDPFGWYRSWEEMLTGMAPLAGLGGE Rv3903c|M.tuberculosis_H37Rv KGFGEEAFGMAKDSWDLGPL-RASIDPFGWYRSWEEMLTGMAPLAGLGGE MSMEG_1870|M.smegmatis_MC2_155 D----LSTGVLNGVINTVAG-TVAFADFDTWKGLGETALAVI-------K TH_3868|M.thermoresistible__bu D----LGVGVVTGLIGTVTG-VVALADADTWRGLANLALTVG-------P MUL_2318|M.ulcerans_Agy99 EGVFKAAVGMVEGIEQLNPQ-RFLIDPQGAAETWKAMTKTGLIN---HLL MLBr_00048|M.leprae_Br4923 SPDERYELDLRTRVRRPPRG-SYQIGILGLKGGAGKTTVTVTLG------ MAB_3131c|M.abscessus_ATCC_199 ASLVQALFNLGEMVTATQSVGDETLELLGGEMNYVVQVVSPEDEDRELLE Mflv_3843|M.gilvum_PYR-GCK GGVVTPPAPGAPGVPVVDEAGVVTPPAPGGPGVPTGGEGGVVTPPAPGAP Mvan_2552|M.vanbaalenii_PYR-1 AGVVTPPGPGAPGVPVVDEAGVVTPPGPGAPGVPVVDEAGVVTPPGPGAP MAV_4644|M.avium_104 GVPGAFDAWKALGKDVTHWDEWG-SNPAEALGKSTFDVATLALPGGPLSK MMAR_5464|M.marinum_M HAPSVLESWKQLGKEVTHWDDWS-RSPGEALGKSEFDLANLFLPGGPISK Mb3933c|M.bovis_AF2122/97 NAPGVVESWKQFGKSLIHWDEWT-TNPNEALGKTVFDAATLALPGGPLSK Rv3903c|M.tuberculosis_H37Rv NAPGVVESWKQFGKSLIHWDEWT-TNPNEALGKTVFDAATLALPGGPLSK MSMEG_1870|M.smegmatis_MC2_155 DPSLIDDIGIAAGKEFFAWDQLTGENPGRGIGEAGFNIAGLFVGG-PLSK TH_3868|M.thermoresistible__bu DPTKMPEILAEMGKTIVAWDKWSGENPGRAAGEAIFNVGSFFT---PVG- MUL_2318|M.ulcerans_Agy99 NPEEAVAADKEMVKGLLHLEDWRRDRPGLGFGGNLFDVATLFVPGAGGAG MLBr_00048|M.leprae_Br4923 ---SMFARVRNDRILVVDADTSCGNLADRAGRFSEANIADLLADKDVKSY MAB_3131c|M.abscessus_ATCC_199 SFDLTYGEDEGGEEDLRTRPPVVTVMGHVDHGKTRLLDTIRKANVREGEA . Mflv_3843|M.gilvum_PYR-GCK GAPVVDEAGVVTPPAPGGPGVPAVGDTAVVTPP---APGAPGTPAVNSVE Mvan_2552|M.vanbaalenii_PYR-1 GVPVVDEAGVVTPPAPGAPGVPVDGGAELVTPP---GPGAPGTPTVSSVE MAV_4644|M.avium_104 LGKFGHSAADALKGLKK---PPGVPKPPEVKPP---AAPKAPDSGQPAP- MMAR_5464|M.marinum_M AASKGRDLADGLQGLKARLRPNEMGEPNPLKRPDASAAEHTPPSTMPQQ- Mb3933c|M.bovis_AF2122/97 LGSKGRDILAGVRGLKERLEPTTPHLEPPATPP----RPGPQPPRIEPP- Rv3903c|M.tuberculosis_H37Rv LGSKGRDILAGVRGLKERLEPTTPHLEPPATPP----RPGPQPPRIEPP- MSMEG_1870|M.smegmatis_MC2_155 GGTVAKGVNKVRRAFDHADSPPLDLPGRHGLDGNDLSVTGSRVPEVPEIR TH_3868|M.thermoresistible__bu ---VLGGTTRATTSLGRAAS----AFGRG---------VDARTPGIPGT- MUL_2318|M.ulcerans_Agy99 AGAKGAAGAARAAEVGGEAADAAAAAGRGGRLAGEVGDLAGAGRTLGDIG MLBr_00048|M.leprae_Br4923 NDIRTHTSVNAVN------------------------------------- MAB_3131c|M.abscessus_ATCC_199 GGITQHIGAYQVAVEHDGTERPITFIDTPGHEA----FTAMRARGAKATD Mflv_3843|M.gilvum_PYR-GCK TFSPPAPPAATPPSSGSVETFSPPAPPAPGTGTNSTVEISTPPPPGTPGL Mvan_2552|M.vanbaalenii_PYR-1 TFSPPAPPAPGTPSSGSIETFSPPAPPTPGTPANSSVEIVTPPPPGVPGV MAV_4644|M.avium_104 ----SGKPGPVAPSGK-PAPGPADGP-LPHSPTESKPPAGGTPPAAEPPK MMAR_5464|M.marinum_M ----EAKQPAAAPQPK-PLR-PSDGHGLPHSPTESKAPPVDKPATGEPVK Mb3933c|M.bovis_AF2122/97 ----ESGHPAPAPAAK-PAPVPANGP-LPHSPTESKPPPVDRP--AEPVA Rv3903c|M.tuberculosis_H37Rv ----ESGHPAPAPAAK-PAPVPANGP-LPHSPTESKPPPVDRP--AEPVA MSMEG_1870|M.smegmatis_MC2_155 QDGIPDSVINPAPSNRLDAPSNPGGPEAPVRPPEPPGPTTHNPGGTRPPG TH_3868|M.thermoresistible__bu --GIPGRGVEPAPS--------PAG-----RPPAQRADAGH--GGERAP- MUL_2318|M.ulcerans_Agy99 KTGRGLTEDLANLGGDLPKADPPVGGRPVALPPPKPAGAPIEPTPRPVES MLBr_00048|M.leprae_Br4923 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 IAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRAQ Mflv_3843|M.gilvum_PYR-GCK PSEGSTTYTTPPTPEITLNPANSGIDIATPPAPGLPGAPLEATANITTPG Mvan_2552|M.vanbaalenii_PYR-1 PGEGSTTYTTPPTPEITLNPANSSIDVATPPGPGVPGVPVEASANVSTPP MAV_4644|M.avium_104 PT--AAPHSGEPKPIATPPESVGKPV-TPAPAEGAPAQPHEPVSARVPPT MMAR_5464|M.marinum_M P---AGAQLGEAR--APGAAARGEKE-LPAQAEHS-EQINTPVSAPGP-- Mb3933c|M.bovis_AF2122/97 P---SSASAGQPRVSAATTPGTHVPHGLPQPGEHVPAQAPPATTLLGGPP Rv3903c|M.tuberculosis_H37Rv P---SSASAGQPRVSAATTPGTHVPHGLPQPGEHVPAQAPPATTLLGGPP MSMEG_1870|M.smegmatis_MC2_155 GGD-GPPPESPHRPVGPADPGPTRGDAPPPHTPSTPEPSHPGSSSVGEPG TH_3868|M.thermoresistible__bu --------------------------VEPPAHETVLDHIENTAGNLNNLG MUL_2318|M.ulcerans_Agy99 VPPGKPALEAPSGAPGSVVPGRSEPAFGPHDPASAPVAGSHPAATAVTPG MLBr_00048|M.leprae_Br4923 -------------------------------LEVLPAAEYSTAQHALSGE MAB_3131c|M.abscessus_ATCC_199 LTEYNLVAEDFGGDTMFVDISARQGTNIEQLLEAVLLTADAALDLRANPD Mflv_3843|M.gilvum_PYR-GCK TPGVPGAPVN---SSIDVATPGEVGVPAAPIERSMTVTTPDTPGAPGAPA Mvan_2552|M.vanbaalenii_PYR-1 VPGVPGAPVN---SSVEVATPAEVGVPGTPIERSTTLTTPPTPGVPGTPV MAV_4644|M.avium_104 VPAADTPAPS---APAASMSAASGPPMPPTPSLPEPASLPSGPSGDLPAE MMAR_5464|M.marinum_M VDGSDLDPTP---ARPHTSRAAPASAMP---HLAGSRSTPSDVCG----- Mb3933c|M.bovis_AF2122/97 VESAPATAHQ---PQWATTPAAPAAAPHS--TPGGVHSTESGPHGRSLSA Rv3903c|M.tuberculosis_H37Rv VESAPATAHQ---PQWATTPAAPAAAPHS--TPGGVHSTESGPHGRSLSA MSMEG_1870|M.smegmatis_MC2_155 IRGNPEPSHT---PPSVDHTPQHAPEPATPAAQNDAPHTSAESNSTPTHQ TH_3868|M.thermoresistible__bu VR-NREDTEE---QPSN--------------------------------- MUL_2318|M.ulcerans_Agy99 ERLSPVTPHVGEPARAPGVPVGAAAGPVPAGAHSAPAAIPAAPGAHVMTG MLBr_00048|M.leprae_Br4923 DWNFAAATVS----KYYNVMLADCGVGLFDPVTRGVLSTASG-------- MAB_3131c|M.abscessus_ATCC_199 MEAQGVAIEAHLDRGRGPVATVLIQRGTLRVGDSIVAGDAYGRVRRMVDE Mflv_3843|M.gilvum_PYR-GCK NAAVDVATPPAPGVPGAPVVGEAGVTTPGAPGAPG-------APANAAVD Mvan_2552|M.vanbaalenii_PYR-1 NSSVEVATPPAPGAPGVPVVDEAGVVTPPGPGAPG-------VPVVGEAG MAV_4644|M.avium_104 T--PPTAGIPHSGEPSAPSSVPPHFPDTPTHGLG---------------- MMAR_5464|M.marinum_M ------PNVVSEGGSPGGHSTPAALDEV---------------------- Mb3933c|M.bovis_AF2122/97 HGSEPTHDGASHGSGHGSGSEPPGLHAPHR-------------------- Rv3903c|M.tuberculosis_H37Rv HGSEPTHDGASHGSGHGSGSEPPGLHAPHR-------------------- MSMEG_1870|M.smegmatis_MC2_155 PSTSDAPASTHSPTQHIGGSVGGEHSAISSDSNIGSAEHHRPVTDESRNW TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 AGRPAELSAPHGGVPHGLGDAGPSGGHPHGLPPHG--------------- MLBr_00048|M.leprae_Br4923 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 HGEDVEEALPSRPVQVIGFTSVPGAGDNLLVVDED--------------- Mflv_3843|M.gilvum_PYR-GCK VATPPAPGVPGAPVVGEAAVTTPGAPGVPGVPAGGDAGVVTPPAPGVPGA Mvan_2552|M.vanbaalenii_PYR-1 VVTPPGPGAPGVPVVDEAGVVTPPGPGAPGVPVVGEAGVVTPPGPGAPGV MAV_4644|M.avium_104 ------DGGAHGPPESDPKNANGHGPHDASLDSGSDHHLPLHPLDSD--- MMAR_5464|M.marinum_M -------GGAPGASAPGEYHGTGGGPGDHGTADGGQSLIIVDGLHAD--- Mb3933c|M.bovis_AF2122/97 -------EQQLAMHSNEPAGEGWHRLSDEAVDPQYGEPLSRHWDFTDNPA Rv3903c|M.tuberculosis_H37Rv -------EQQLAMHSNEPAGEGWHRLSDEAVDPQYGEPLSRHWDFTDNPA MSMEG_1870|M.smegmatis_MC2_155 ADEQAHRPAEQQPAHNAAAEQPVTHDRNSAETNESREPAYSSAVNGPQPA TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 ----GGPHGPGDASHGARHAEPPRDGTAHGTADGGDAHGDDVSGHGLSAE MLBr_00048|M.leprae_Br4923 ------------------VVIVTSTSVDAARQAAIALDWLRHNGYQDLLS MAB_3131c|M.abscessus_ATCC_199 ------RIARQIADRRSARKRNALAARSRKRISLDDLDAALKETSQLNLI Mflv_3843|M.gilvum_PYR-GCK PVVGEAGVTTPGAPGVPGVPAGGDAGVVTPPAPGVPGAPAATEAGLATPP Mvan_2552|M.vanbaalenii_PYR-1 PVVDEAGVVTPPGPGAPGVPVVGEAGVVTPPGPGAPGVPVVDEAGVVTPP MAV_4644|M.avium_104 DLAALAHYTGPGYQELNFALREGALDVSQQAR--------VDALQKALEK MMAR_5464|M.marinum_M DLSALADYTGSGYLDLNNALRSDILDASLNAR--------VAALNSALQK Mb3933c|M.bovis_AF2122/97 DRSRINPVVAQLMEDPNAPFGRDPQGQPYTQERYQERFNSVGPWGQQYSN Rv3903c|M.tuberculosis_H37Rv DRSRINPVVAQLMEDPNAPFGRDPQGQPYTQERYQERFNSVGPWGQQYSN MSMEG_1870|M.smegmatis_MC2_155 MGPMMSPGVGSGPGSPMTPHAPGPVHGGGESPSPAAKLPTPDTSTRGPET TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 KRDEIIAMRKGSRPDPSEYLSPEYIQG-HLDRFTGGATRFMPESNLDKYG MLBr_00048|M.leprae_Br4923 RACVVINHVMPKEPNIASKDLVQQFEQQIQPG---------------RVV MAB_3131c|M.abscessus_ATCC_199 LKGDNAGTVEALEEALLGIAIDDEVQLRVIDRGVGGVTETNVNLASASDA Mflv_3843|M.gilvum_PYR-GCK GPGAPGAPVVGDAGVATPPGPGVPGAPIVDEAGLATPPAP-----VAPVE Mvan_2552|M.vanbaalenii_PYR-1 GPGAPGVPVVDEAGVVTPPGPGAPGVPVVDEAGVVTPPAPPAAAPGAPID MAV_4644|M.avium_104 LPVYEGAVVRGTNLPADVLEQYRPGEVITEAAFTSTSTDHTVAQSSAFAG MMAR_5464|M.marinum_M LPTYDGTVVRGTDLPPEVVAQYLPGEVITEVAFLSTTTDPAVAQSPTFAG Mb3933c|M.bovis_AF2122/97 FPPNNGAVP-GTRIAYTNLEKFLSDYGPQLDRIGGDQGKYLAIMEHGRPA Rv3903c|M.tuberculosis_H37Rv FPPNNGAVP-GTRIAYTNLEKFLSDYGPQLDRIGGDQGKYLAIMEHGRPA MSMEG_1870|M.smegmatis_MC2_155 RPSHTGSPETPRAQQPSAVGPTPGSTPSAPVHSSADQSRQSASTSPASST TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 IAQRDGTSFVMPKSEADAMIAGTGGDLRLMEEELGLPEGFLDSNQIVRID MLBr_00048|M.leprae_Br4923 VLPWDKHIAAGTEIRLDRLDPLYRRRILELAAALSDDFERAGRH------ MAB_3131c|M.abscessus_ATCC_199 IIIGFNVRAEGKATELANREGVDIRYYSVIYQAIDEIESALKGMLKPVYE Mflv_3843|M.gilvum_PYR-GCK GAGGAVPPAGPPPAPVFGDAGAPVEAAAGGAPVEAAAGVTGGGSVAGAGA Mvan_2552|M.vanbaalenii_PYR-1 AAAASVAPSGPPAAPVLGEAGVVAPPAP-----------PGGGAPGGGAP MAV_4644|M.avium_104 NTEFRIWSTTGR----DVSSVSMYPD-----EKEILFPAG-SKFYVVSKT MMAR_5464|M.marinum_M NVEFRIVSRTGR----DVSSVSMFPD-----EREILFPAG-TKFYVIDKT Mb3933c|M.bovis_AF2122/97 SWEQRALHVTSLRDPYHAYTIDWLPEGWFIEVSEVAPGCGQPGGSIQVRI Rv3903c|M.tuberculosis_H37Rv SWEQRALHVTSLRDPYHAYTIDWLPEGWFIEVSEVAPGCGQPGGSIQVRI MSMEG_1870|M.smegmatis_MC2_155 SEQTAPKEHGTAPGSSVPPSDSHHNSPPPKPEPPHDSSGLEPPVHDGDAF TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 IEDPRQFNLRIPSGNEAGANEQWIPGG----------LLPTGASEAVVDG MLBr_00048|M.leprae_Br4923 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 EVELGRAEIRAMFRSSKVGNIAGCLVTSGIIRRNAKARLLRDNIVVAETV Mflv_3843|M.gilvum_PYR-GCK GGGAGGAAGGAGVEGASGAVGAAGGPGAGAAPAAAGGAAPGGAPGGPVAG Mvan_2552|M.vanbaalenii_PYR-1 GAGVG---TGAPIEGAAGAGGVPAAPLAANAGAAT---PPAAATGG---- MAV_4644|M.avium_104 VDPQTG-RTIIEMIER---------------------------------- MMAR_5464|M.marinum_M LDALTG-RTIIDMIER---------------------------------- Mb3933c|M.bovis_AF2122/97 FDHQNEMRKVEELIRRGVLRQ----------------------------- Rv3903c|M.tuberculosis_H37Rv FDHQNEMRKVEELIRRGVLRQ----------------------------- MSMEG_1870|M.smegmatis_MC2_155 TDPAKSDLDYNPMLDENGHYVPGSLPSYDELLRLTRTEPDSAHYWSGRDA TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 GKVPQGDYTVTDVFEEK--------------------------------- MLBr_00048|M.leprae_Br4923 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 TISSLRREKDDVVEVRDGYECGLTLTYNDIKEGDVIEAYELREKERV--- Mflv_3843|M.gilvum_PYR-GCK GGPVGGPGALPAPGAPIVGEAGVVSPPAPGVPGGAAAVPAGAVTPPAPGV Mvan_2552|M.vanbaalenii_PYR-1 ------------AGAPIDAAAGAAAPPAP----------------PAP-- MAV_4644|M.avium_104 -------------------------------------------------- MMAR_5464|M.marinum_M -------------------------------------------------- Mb3933c|M.bovis_AF2122/97 -------------------------------------------------- Rv3903c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 NGVGVGPDGSGIAERIAEGSNGTTLEMTLERNGVHPLPAWNRHDPESVRF TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00048|M.leprae_Br4923 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK PGAPVFGEAGVVTPPAPGVPGGAAAVPAGVVTPPAPGVPGGAAAVPAGAV Mvan_2552|M.vanbaalenii_PYR-1 -GAPIFGEAGVAAPPLPPAPGGAGAVPAGVVTPPVPGVPGGAGAVPAGAV MAV_4644|M.avium_104 -------------------------------------------------- MMAR_5464|M.marinum_M -------------------------------------------------- Mb3933c|M.bovis_AF2122/97 -------------------------------------------------- Rv3903c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 WEDASAAYAENARGDVTAIVGSDLRPGNIWQTVEIPRLMDNPNVTRIVQI TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00048|M.leprae_Br4923 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK TPPAPGVPGAPVFGDAGVATPPVPGVPGGGTTVPAASVTPPAPGVPGGAS Mvan_2552|M.vanbaalenii_PYR-1 TPPTP----------------PVPGSSSGG-------------------- MAV_4644|M.avium_104 -------------------------------------------------- MMAR_5464|M.marinum_M -------------------------------------------------- Mb3933c|M.bovis_AF2122/97 -------------------------------------------------- Rv3903c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 DPDTG--RATELFHRTTSADGPAPNGQMEPTARHDGLTSETDSRTLRDTD TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00048|M.leprae_Br4923 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK TVPGNAGTPSTPGLPPGSTDTYINYPAPPVPPTPPNSTGVSAGTPGSPAP Mvan_2552|M.vanbaalenii_PYR-1 ---------------------FVNYPAPPVPPTPPNSAGVNTGTPGSPIP MAV_4644|M.avium_104 -------------------------------------------------- MMAR_5464|M.marinum_M -------------------------------------------------- Mb3933c|M.bovis_AF2122/97 -------------------------------------------------- Rv3903c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 QDSIDRASNKPDADVRAEPSHSWRDDTDQQRGDDRGYSDDDGPRENAVGP TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00048|M.leprae_Br4923 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK GTPGSTLTLTDLLTPPGIARTLQNTASSVMGATPPGTPPVPGGSGSVSLA Mvan_2552|M.vanbaalenii_PYR-1 GTPGSTLTISDLLTPPGVARTVQNTASSVMSIAPPGTPPVPGGAGSVSVG MAV_4644|M.avium_104 -------------------------------------------------- MMAR_5464|M.marinum_M -------------------------------------------------- Mb3933c|M.bovis_AF2122/97 -------------------------------------------------- Rv3903c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 DGRYKISGHGDYHSGDGTFTVPADTSVTVYGEHGSPITQSLGNLIESGGD TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00048|M.leprae_Br4923 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK VPGTPSPIAPLAATGLSNLVSPPSLTIPSIPGLPVPLPNTVPVPSDLLCV Mvan_2552|M.vanbaalenii_PYR-1 VPAPPSPLTPLAATGLSNLVSPPSLTIPSIPGLPVPLPNEVPVPSDLLCV MAV_4644|M.avium_104 -------------------------------------------------- MMAR_5464|M.marinum_M -------------------------------------------------- Mb3933c|M.bovis_AF2122/97 -------------------------------------------------- Rv3903c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 TSRVFKKTYYPGETMPNYTLLPPDDMNIVGTPHTVDRATTLSDLLQPNMG TH_3868|M.thermoresistible__bu -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00048|M.leprae_Br4923 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK GTDWSASQGDSAATPPAAEVPR-VVTGAAPTGDRRDRWGNR----- Mvan_2552|M.vanbaalenii_PYR-1 GTDWSATQGDSATTPVNAEIPRALVTGAAPVGDRRDRWDTR----- MAV_4644|M.avium_104 ---------------------------------------------- MMAR_5464|M.marinum_M ---------------------------------------------- Mb3933c|M.bovis_AF2122/97 ---------------------------------------------- Rv3903c|M.tuberculosis_H37Rv ---------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 AVDFVACLGSWNHRVFDVHGIYHQDTYDFIEKYPWPEPENLGDDDW TH_3868|M.thermoresistible__bu ---------------------------------------------- MUL_2318|M.ulcerans_Agy99 ---------------------------------------------- MLBr_00048|M.leprae_Br4923 ---------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 ----------------------------------------------