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APLAVDPAALDGAGAAVVAAGEGLEPVIASLSAVLAGCAGMAGDDPVGAAVGRGYDRAAAKVFSAMAATR NGLCSIGDGVRMSAHNYSLAEAMSDVTRRAAALPAPTLTTCIVAASAPSAVGTADSAPAGWGWIAPYIGM IWPTGNLSKLRTAASEWTAEGTKFALVETQLTAGPLGAIRSQQLPESGLIERAFTDAYVSTTSVVGQCQT IAAQLDRYADQIDEVHAAILDLLARICDPLTGIKEVWEVLTGEDEDEIERIAHEIAAVVDHFAAEANALS AQFNAALVHADTVLDTMARHAAREWDQFLHGNPVGAIVDFAGQRLKGLGEAAWGLAETALTYNQIRALLD PLGYARDVGSMAQGMAPLVGLGDDHAPSVLESWKQLGKEVTHWDDWSRSPGEALGKSEFDLANLFLPGGP ISKAASKGRDLADGLQGLKARLRPNEMGEPNPLKRPDASAAEHTPPSTMPQQEAKQPAAAPQPKPLRPSD GHGLPHSPTESKAPPVDKPATGEPVKPAGAQLGEARAPGAAARGEKELPAQAEHSEQINTPVSAPGPVDG SDLDPTPARPHTSRAAPASAMPHLAGSRSTPSDVCGPNVVSEGGSPGGHSTPAALDEVGGAPGASAPGEY HGTGGGPGDHGTADGGQSLIIVDGLHADDLSALADYTGSGYLDLNNALRSDILDASLNARVAALNSALQK LPTYDGTVVRGTDLPPEVVAQYLPGEVITEVAFLSTTTDPAVAQSPTFAGNVEFRIVSRTGRDVSSVSMF PDEREILFPAGTKFYVIDKTLDALTGRTIIDMIER*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_5464 | - | - | 100% (806) | ADP-ribosyltransferse |
M. marinum M | MMAR_3072 | - | 2e-66 | 29.90% (719) | hypothetical protein MMAR_3072 |
M. marinum M | MMAR_0611 | - | 2e-10 | 27.75% (191) | iron-sulphur-binding reductase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3933c | - | 0.0 | 54.62% (650) | hypothetical protein Mb3933c |
M. gilvum PYR-GCK | Mflv_4039 | infB | 1e-09 | 32.52% (206) | translation initiation factor IF-2 |
M. tuberculosis H37Rv | Rv3903c | - | 0.0 | 54.62% (650) | hypothetical protein Rv3903c |
M. leprae Br4923 | MLBr_01556 | infB | 3e-06 | 29.32% (191) | translation initiation factor IF-2 |
M. abscessus ATCC 19977 | MAB_3131c | - | 5e-09 | 28.71% (209) | translation initiation factor IF-2 (InfB) |
M. avium 104 | MAV_4644 | - | 0.0 | 51.86% (833) | hypothetical protein MAV_4644 |
M. smegmatis MC2 155 | MSMEG_1870 | - | 2e-37 | 25.14% (700) | hypothetical protein MSMEG_1870 |
M. thermoresistible (build 8) | TH_3868 | - | 1e-13 | 23.31% (369) | PUTATIVE putative conserved hypothetical protein |
M. ulcerans Agy99 | MUL_2318 | - | 1e-64 | 30.00% (720) | hypothetical protein MUL_2318 |
M. vanbaalenii PYR-1 | Mvan_2314 | infB | 5e-10 | 27.12% (236) | translation initiation factor IF-2 |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_5464|M.marinum_M ------------MAPLAVDPAALDGAGAAVVAAGEGLEPVIASLSAVLAG MAV_4644|M.avium_104 ------------MAPLACDPTALDHAGATVVAAGESLGSVISTLTAALAG Mb3933c|M.bovis_AF2122/97 ------------MAPLAVDPAALDSAGGAVVAAGAGLGAVISSLTAALAG Rv3903c|M.tuberculosis_H37Rv ------------MAPLAVDPAALDSAGGAVVAAGAGLGAVISSLTAALAG MSMEG_1870|M.smegmatis_MC2_155 MPSNSGGGGGVSGIRIEVDPQVLIRAGESMLSLGNQLDMLMGALGPMLS- TH_3868|M.thermoresistible__bu -------------------------------------------------- Mflv_4039|M.gilvum_PYR-GCK ---------MAGKARVHELAKELGVTSKEVLARLGEQGEFVKSASSTVEA Mvan_2314|M.vanbaalenii_PYR-1 ---------MAGKARVHELAKELGVTSKEVLARLSEQGEFVKSASSTVEA MAB_3131c|M.abscessus_ATCC_199 ---------MAGKARVHELAKELGVTSKEVLARLSDQGEFVKSASSTVEA MLBr_01556|M.leprae_Br4923 ---------MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEA MUL_2318|M.ulcerans_Agy99 ------MGKNPGVAPLSVDPEALSGAGSAVAAAG---DALAAALSSLTTG MMAR_5464|M.marinum_M CAGMAGDDPVGAAVGRGYDRAAAKVFSAMAATRNGLCSIG---------- MAV_4644|M.avium_104 TSGMAGDDPVGAALGRRYDGAAAKLIQAMADTRNGLCSIG---------- Mb3933c|M.bovis_AF2122/97 CAGMAGDDPAGAVFGRSYDGSAAALVQAMSVARNGLCNLG---------- Rv3903c|M.tuberculosis_H37Rv CAGMAGDDPAGAVFGRSYDGSAAALVQAMSVARNGLCNLG---------- MSMEG_1870|M.smegmatis_MC2_155 SGIASGIDLAGLAMALDYGDLTQKFSNTLANGANTFKTVG---------- TH_3868|M.thermoresistible__bu -------------------------------------------------- Mflv_4039|M.gilvum_PYR-GCK PVARRLRESFGGNKPDAVKPAAG--ASNGAPAKPSAPGA-------RPGP Mvan_2314|M.vanbaalenii_PYR-1 PVARRLRESYGGSKSDKTKAAPSGNGAAGATVKPSAPQS-------RPGP MAB_3131c|M.abscessus_ATCC_199 PVARRLRESFGGGD----KPAPA--ASNGAAAEAAAPPK-------KAGP MLBr_01556|M.leprae_Br4923 PVARRLRESFGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVA MUL_2318|M.ulcerans_Agy99 FSANTGQDTAGEVFGLAYQDAAESLVKAAGAGINALRHNG---------- MMAR_5464|M.marinum_M -----DGVRMSAHNYSLAEAMSDVTRRAAALPAP-TLTTCIVAASAPSAV MAV_4644|M.avium_104 -----DGVRMSAHNYAVAEAMSDLAGRASALPAP-QVTGPLTVGAPPSAV Mb3933c|M.bovis_AF2122/97 -----DGVRMSAHNYSLAEAMSDVAGRAAPLPAP-PPSGCVGVGAPPSAV Rv3903c|M.tuberculosis_H37Rv -----DGVRMSAHNYSLAEAMSDVAGRAAPLPAP-PPSGCVGVGAPPSAV MSMEG_1870|M.smegmatis_MC2_155 -----LRLQASGHNYANADAVSTIGGGAPTGGVKGKFDETKPVDARDSPS TH_3868|M.thermoresistible__bu -------------------------------------------------- Mflv_4039|M.gilvum_PYR-GCK RPGPPAPAQPKEPPAPAAPAAAA-PAPAAPAPPAAPPAPAASAAPPSAPE Mvan_2314|M.vanbaalenii_PYR-1 KPGPPVAQQPAAPAAPPAAPPAP-PTPAAAPPSPAPAAPAA--ATPAEPA MAB_3131c|M.abscessus_ATCC_199 KPGAPKPAPKKVAEPVVEAPVAP-EPPAAPAAPAAPAPKPSPAARPAAAE MLBr_01556|M.leprae_Br4923 GNGATTAAPVQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPL MUL_2318|M.ulcerans_Agy99 -----AKIQLSASNYSAAEAASTLGGGAGVLPAPSEPAQFTAPGAPG-TL MMAR_5464|M.marinum_M GTADSAPAGWGWIAPYIG-MIWPT------------GNLSKLRTAASEWT MAV_4644|M.avium_104 GHGSGAPAGWGWVAPSIG-MIWPT------------GDSAKLRAAAAAWA Mb3933c|M.bovis_AF2122/97 GGGGGAPKGWGWVAPYIG-MIWPN------------GDSTKLRAAAVAWR Rv3903c|M.tuberculosis_H37Rv GGGGGAPKGWGWVAPYIG-MIWPN------------GDSTKLRAAAVAWR MSMEG_1870|M.smegmatis_MC2_155 LSVVPPPPAWYLVGSFLGPTAWPS------------GNPAMLRLTAAQWE TH_3868|M.thermoresistible__bu ----------------------------------------MLRLTVAQWR Mflv_4039|M.gilvum_PYR-GCK APSAR--PTPGP-RPGPG-GPKPG-APKPAPRTPRVGNNPFSSQQPVERP Mvan_2314|M.vanbaalenii_PYR-1 APSARPGPTPGP-RPGPS-APKPG-APKPAARTPRVGNNPFSSQQPVERP MAB_3131c|M.abscessus_ATCC_199 AAAPAPAPAPAP-RPGATPGPKPG-AP----RVPRVGNNPFSSAQPAERP MLBr_01556|M.leprae_Br4923 PGQQGTPAAPHPGHPGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARP MUL_2318|M.ulcerans_Agy99 GSGVLAPALWSVVEAFVG-DLWPN------------GDVAGLHAAAGHWR MMAR_5464|M.marinum_M AEGTK------------------------FALVETQLTAGPLGAIRSQQL MAV_4644|M.avium_104 TAGAN------------------------FMAAETAAGGGTMAAIGAQQI Mb3933c|M.bovis_AF2122/97 SAGTQ------------------------FALTEIQSTAGPMGVIRAQQL Rv3903c|M.tuberculosis_H37Rv SAGTQ------------------------FALTEIQSTAGPMGVIRAQQL MSMEG_1870|M.smegmatis_MC2_155 NLATG------------------------FSAVSNQVSG-SSTAVSTQKI TH_3868|M.thermoresistible__bu NFAHG------------------------FAVFEPQLAP-VLAVVSAQNT Mflv_4039|M.gilvum_PYR-GCK APRPQGPAGPGGPRPGPGAGGPRPGGGPRPGATPGNMPPRPVGGPRPGGG Mvan_2314|M.vanbaalenii_PYR-1 APRPQ---GPGGPRPGPGAGGPRPGGGPRPGASPGSMPPRPQG-ARPGGG MAB_3131c|M.abscessus_ATCC_199 APRPQ------APRPG----APRPGG-----ASPSNMPPRPSPGSMGPRP MLBr_01556|M.leprae_Br4923 IPRPP------APRPS---------------ASPSSMSPRPGG-AVGGGG MUL_2318|M.ulcerans_Agy99 DFAAA-------------------------LNGVQGALNSPKSVVAGQDI MMAR_5464|M.marinum_M PES-----GLIERAFTDAYVSTTSVVGQCQT-----------------IA MAV_4644|M.avium_104 PEG-----AAINKALADASSATADVARQCQT-----------------IA Mb3933c|M.bovis_AF2122/97 PEA-----GLIESAFADAYASTTAVVGQCHQ-----------------LA Rv3903c|M.tuberculosis_H37Rv PEA-----GLIESAFADAYASTTAVVGQCHQ-----------------LA MSMEG_1870|M.smegmatis_MC2_155 PEA-----SQIAQAHADLADGVADLANQATN-----------------LA TH_3868|M.thermoresistible__bu PET-----PAIVSGLDELARGISALTDASVE-----------------VA Mflv_4039|M.gilvum_PYR-GCK PRP--GGGPRPGAGPRPTPGGAGRPGGGGGG--NYRGG--GAGGGGGAGG Mvan_2314|M.vanbaalenii_PYR-1 PRP--GGGPRPGGGPRPTPGGAGRPGGGGGGGGNYRGG--GAGG--GAPA MAB_3131c|M.abscessus_ATCC_199 PRP--GGGPRPGGGPR--PGGAGRPGGGGGG--NYRGGGTGTGAPAGGPP MLBr_01556|M.leprae_Br4923 PRPPRTGVPRPGGGRPGAPVGG-RSDAGGGN---YRGG--GVGA---LPG MUL_2318|M.ulcerans_Agy99 PEG-----VQIQQVLSAIGSDLAGVGAQCRK-----------------LA *. MMAR_5464|M.marinum_M AQLDRYADQ----------IDEVHAAILDLLARICDPLTGIKEVWEVLTG MAV_4644|M.avium_104 AQLNSYAAK----------VDQVHAAILDLLSRICDPLTGIKEVWDLLTD Mb3933c|M.bovis_AF2122/97 AQLDAYAAR----------IDAVHAAVLDLLARICDPLTGIKEVWEFLTD Rv3903c|M.tuberculosis_H37Rv AQLDAYAAR----------IDAVHAAVLDLLARICDPLTGIKEVWEFLTD MSMEG_1870|M.smegmatis_MC2_155 ETLNTFADN----------VQETQDAIRRLLDRVASIDGIINTVKGIFTG TH_3868|M.thermoresistible__bu REVEDFAAT----------VQGTQDAIRRLVGRVS-ISGLFHTVKGILTG Mflv_4039|M.gilvum_PYR-GCK AAAGGFRGRPGGG--GG--RPGQRGGAAGAFGRPGGAPKRGRKSKRAKRA Mvan_2314|M.vanbaalenii_PYR-1 AGGGGFRGRPGGG--GGGGRPGQRGGAAGAFGRPGGAPKRGRKSKRAKRA MAB_3131c|M.abscessus_ATCC_199 GAGGGFRGRPGGG--GGGGRPGQRGGAAGAFGRPGGAPKRGRKSKRAKRA MLBr_01556|M.leprae_Br4923 GGSGGFRGRPGGGGHGGGGRPGQRGGAAGAFGRPGGAPRRGRKSKRQKRQ MUL_2318|M.ulcerans_Agy99 GALDDFADE----------VADTQDAIRDLLDRFGSVSGLWNQVVAIFEG : : . . * . MMAR_5464|M.marinum_M EDEDEIERIAHEIAAVVDHFAAEANALSAQFNAALVHADTVLDTMARHAA MAV_4644|M.avium_104 EDEDEIKKIADDIRTVVDNFGREADTLGGQIEATVSAVAAATENMSHWAG Mb3933c|M.bovis_AF2122/97 QDEDEIQRIAHDIAVVVDQFSGEVDALAAEITAVVSHAEAVITAMADHAG Rv3903c|M.tuberculosis_H37Rv QDEDEIQRIAHDIAVVVDQFSGEVDALAAEITAVVSHAEAVITAMADHAG MSMEG_1870|M.smegmatis_MC2_155 DALDIIKEVVEDIRTLLGNFQRQVKAVGALLEELKNALNDTVTKFQKWAD TH_3868|M.thermoresistible__bu DGKDILREVARDVRTVLDNFQRQVKGVIGLLEELATLIGDAATAFQKWLR Mflv_4039|M.gilvum_PYR-GCK EYENMQAPVVGGVRLPHGNGETIRLARGASLSDFADKINANPASLVQALF Mvan_2314|M.vanbaalenii_PYR-1 EYENMQAPVVGGVRLPHGNGETIRLARGASLSDFAEKINANPASLVQALF MAB_3131c|M.abscessus_ATCC_199 EYENMQAPVVGGVRLPHGNGEVIRLARGASLSDFAEKIDANPASLVQALF MLBr_01556|M.leprae_Br4923 EYDSMQAPVVGGVRLPHGNGETIRLARGASLSDFAEKIDANPAALVQALF MUL_2318|M.ulcerans_Agy99 DALDEIKEIAEDIRAVLSNLGRQARAQQQLMQQGMQAIDGLVVGMQRYVR : . :. : .: : : MMAR_5464|M.marinum_M REWDQFLHGNPVG---AIVDFAGQRLKGLGEAAWGLAETALTYNQIRALL MAV_4644|M.avium_104 KEWDHFLHGTPVG---RALNQVGQAFKGVGEEGWGFLKGLYEVSPNRMLL Mb3933c|M.bovis_AF2122/97 KQWDRFLHSNPVG---VVIDGTGQQLKGFGEEAFGMAKDSWDLGPLRASI Rv3903c|M.tuberculosis_H37Rv KQWDRFLHSNPVG---VVIDGTGQQLKGFGEEAFGMAKDSWDLGPLRASI MSMEG_1870|M.smegmatis_MC2_155 KNLREILGDQVGG---AISDIIKFQTD----LSTGVLNGVINTVAGTVAF TH_3868|M.thermoresistible__bu PNLVAVFGEQVGG---AMADRIELRTD----LGVGVVTGLIGTVTGVVAL Mflv_4039|M.gilvum_PYR-GCK NLGEMVTATQSVND--ETLELLGGEMNYVVQVVSPEDEDRELLQSFDLSY Mvan_2314|M.vanbaalenii_PYR-1 NLGEMVTATQSVGD--ETLELLGGEMNYVVQVVSPEDEDRELLESFDLTY MAB_3131c|M.abscessus_ATCC_199 NLGEMVTATQSVGD--ETLELLGGEMNYVVQVVSPEDEDRELLESFDLTY MLBr_01556|M.leprae_Br4923 NLGEMVTATQSVGD--ETLELLGSEMNYNVQVVSPEDEDRELLEPFDLTY MUL_2318|M.ulcerans_Agy99 GQLTQLLGQDVGNPVATVFDTYTNTQEGVFKAAVGMVEGIEQLNPQRFLI . . : . MMAR_5464|M.marinum_M DPLGYARDVGSMAQGMAPLVGLGDDHAPSVLESWKQLGKEVTHWDDWS-R MAV_4644|M.avium_104 DPVGYGKTMAGMVEGAGTLVGLGPDGVPGAFDAWKALGKDVTHWDEWG-S Mb3933c|M.bovis_AF2122/97 DPFGWYRSWEEMLTGMAPLAGLGGENAPGVVESWKQFGKSLIHWDEWT-T Rv3903c|M.tuberculosis_H37Rv DPFGWYRSWEEMLTGMAPLAGLGGENAPGVVESWKQFGKSLIHWDEWT-T MSMEG_1870|M.smegmatis_MC2_155 ADFDTWKGLGETALAVI-------KDPSLIDDIGIAAGKEFFAWDQLTGE TH_3868|M.thermoresistible__bu ADADTWRGLANLALTVG-------PDPTKMPEILAEMGKTIVAWDKWSGE Mflv_4039|M.gilvum_PYR-GCK GEDEGGEDDLEFRPPVVTVMG---HVDHGKTRLLDTIRDATVREGEAGGI Mvan_2314|M.vanbaalenii_PYR-1 GEDEGGEEDLEIRPPVVTVMG---HVDHGKTRLLDTIRNATVREGEAGGI MAB_3131c|M.abscessus_ATCC_199 GEDEGGEEDLRTRPPVVTVMG---HVDHGKTRLLDTIRKANVREGEAGGI MLBr_01556|M.leprae_Br4923 GEDQGDEDELQVRPPVVTVMG---HVDHGKTRLLDTIRKANVREAEAGGI MUL_2318|M.ulcerans_Agy99 DPQGAAETWKAMTKTGLIN---HLLNPEEAVAADKEMVKGLLHLEDWRRD . . . MMAR_5464|M.marinum_M SPGEALGKSEFDLANLFLPGGPISKAASKGRDLADGLQGLKARLRPNEMG MAV_4644|M.avium_104 NPAEALGKSTFDVATLALPGGPLSKLGKFGHSAADALKGLKK---PPGVP Mb3933c|M.bovis_AF2122/97 NPNEALGKTVFDAATLALPGGPLSKLGSKGRDILAGVRGLKERLEPTTPH Rv3903c|M.tuberculosis_H37Rv NPNEALGKTVFDAATLALPGGPLSKLGSKGRDILAGVRGLKERLEPTTPH MSMEG_1870|M.smegmatis_MC2_155 NPGRGIGEAGFNIAGLFVGG-PLSKGGTVAKGVNKVRRAFDHADSPPLDL TH_3868|M.thermoresistible__bu NPGRAAGEAIFNVGSFFT---PVG----VLGGTTRATTSLGRAAS----A Mflv_4039|M.gilvum_PYR-GCK TQHIGAYQVTVDLDGNERPITFIDTPGHEAFTAMRARGAKATDIAILVVA Mvan_2314|M.vanbaalenii_PYR-1 TQHIGAYQVTVDLDGTERPITFIDTPGHEAFTAMRARGAKATDIAILVVA MAB_3131c|M.abscessus_ATCC_199 TQHIGAYQVAVEHDGTERPITFIDTPGHEAFTAMRARGAKATDIAILVVA MLBr_01556|M.leprae_Br4923 TQHIGAYQVGVDLDGSERLITFIDTPGHEAFTAMRARGAKATDIAILVVA MUL_2318|M.ulcerans_Agy99 RPGLGFGGNLFDVATLFVPGAGGAGAGAKGAAGAARAAEVGGEAADAAAA . .: MMAR_5464|M.marinum_M EPNPLKRPDASAAEHTPPSTMPQQ-----------EAKQPAAAPQPK-PL MAV_4644|M.avium_104 KPPEVKPP---AAPKAPDSGQPAP-----------SGKPGPVAPSGK-PA Mb3933c|M.bovis_AF2122/97 LEPPATPP----RPGPQPPRIEPP-----------ESGHPAPAPAAK-PA Rv3903c|M.tuberculosis_H37Rv LEPPATPP----RPGPQPPRIEPP-----------ESGHPAPAPAAK-PA MSMEG_1870|M.smegmatis_MC2_155 PGRHGLDGNDLSVTGSRVPEVPEIRQD------GIPDSVINPAPSNRLDA TH_3868|M.thermoresistible__bu FGRG---------VDARTPGIPGT---------GIPGRGVEPAPS----- Mflv_4039|M.gilvum_PYR-GCK ADDGVMPQTVEAVNHAQAADVPIVVAVNKIDKEGADPAKIRGQLTEYGLV Mvan_2314|M.vanbaalenii_PYR-1 ADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRGQLTEYGLV MAB_3131c|M.abscessus_ATCC_199 ADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRAQLTEYNLV MLBr_01556|M.leprae_Br4923 ADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRGQLTEYGLV MUL_2318|M.ulcerans_Agy99 AGRGGRLAGEVGDLAGAGRTLGDIGKTG-----RGLTEDLANLGGDLPKA MMAR_5464|M.marinum_M R-PSDGHGLPHSPTESKAP---PVDKPATGEPVKP--AGAQLGEAR--AP MAV_4644|M.avium_104 PGPADGP-LPHSPTESKPP---AGGTPPAAEPPKPT-AAPHSGEPKPIAT Mb3933c|M.bovis_AF2122/97 PVPANGP-LPHSPTESKPP---PVDRP--AEPVAP--SSASAGQPRVSAA Rv3903c|M.tuberculosis_H37Rv PVPANGP-LPHSPTESKPP---PVDRP--AEPVAP--SSASAGQPRVSAA MSMEG_1870|M.smegmatis_MC2_155 PSNPGGPEAPVRPPEPPGP---TTHNPGGTRPPGGGDGPPPESPHRPVGP TH_3868|M.thermoresistible__bu ---PAG-----RPPAQRAD---AGH--GGERAP----------------- Mflv_4039|M.gilvum_PYR-GCK PEEYGGDTMFVDISAKAGT---NIEALLEAVVLTAD--ASLDLRANPDME Mvan_2314|M.vanbaalenii_PYR-1 PEEYGGDAMFVDISAKQGT---NIEALLEAVILTAD--ASLDLRANPDME MAB_3131c|M.abscessus_ATCC_199 AEDFGGDTMFVDISARQGT---NIEQLLEAVLLTAD--AALDLRANPDME MLBr_01556|M.leprae_Br4923 AEDFGGDTMFIDISAKVGT---NIEALLEAVLLTAD--AALDLRANSGME MUL_2318|M.ulcerans_Agy99 DPPVGGRPVALPPPKPAGAPIEPTPRPVESVPPGKPALEAPSGAPGSVVP * . MMAR_5464|M.marinum_M GAAARGEKE-LPAQAEHS-EQINTPVSAPGP--VDGSDLDPTPARPHTSR MAV_4644|M.avium_104 PPESVGKPV-TPAPAEGAPAQPHEPVSARVPPTVPAADTPAPSAPAASMS Mb3933c|M.bovis_AF2122/97 TTPGTHVPHGLPQPGEHVPAQAPPATTLLGGPPVESAPATAHQPQWATTP Rv3903c|M.tuberculosis_H37Rv TTPGTHVPHGLPQPGEHVPAQAPPATTLLGGPPVESAPATAHQPQWATTP MSMEG_1870|M.smegmatis_MC2_155 ADPGPTRGDAPPPHTPSTPEPSHPGSSSVGEPGIRGNPEPSHTPPSVDHT TH_3868|M.thermoresistible__bu ---------VEPPAHETVLDHIENTAGNLNNLGVR-NREDTEEQPSN--- Mflv_4039|M.gilvum_PYR-GCK AQGVAIEAHLDRGRGPVATVLIQRGTLRVGDSVVAGDAYGRVRRMVDEHG Mvan_2314|M.vanbaalenii_PYR-1 AQGVAIEAHLDRGRGPVATVLIQRGTLRVGDSVVAGDAYGRVRRMVDEHG MAB_3131c|M.abscessus_ATCC_199 AQGVAIEAHLDRGRGPVATVLIQRGTLRVGDSIVAGDAYGRVRRMVDEHG MLBr_01556|M.leprae_Br4923 AQGVAIEAHLDRGRGPVATVLVQRGTLRIGDSVVAGDAYGRVRRMVDEHG MUL_2318|M.ulcerans_Agy99 GRSEPAFGPHDPASAPVAGSHPAATAVTPGERLSPVTPHVGEPARAPGVP MMAR_5464|M.marinum_M AAPASAMP---HLAGSRSTPSDVCG-----------PNVVSEGGSPGGHS MAV_4644|M.avium_104 AASGPPMPPTPSLPEPASLPSGPSGDLPAET--PPTAGIPHSGEPSAPSS Mb3933c|M.bovis_AF2122/97 AAPAAAPHS--TPGGVHSTESGPHGRSLSAHGSEPTHDGASHGSGHGSGS Rv3903c|M.tuberculosis_H37Rv AAPAAAPHS--TPGGVHSTESGPHGRSLSAHGSEPTHDGASHGSGHGSGS MSMEG_1870|M.smegmatis_MC2_155 PQHAPEPATPAAQNDAPHTSAESNSTPTHQPSTSDAPASTHSPTQHIGGS TH_3868|M.thermoresistible__bu -------------------------------------------------- Mflv_4039|M.gilvum_PYR-GCK EDVEEALPSRPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKRNA Mvan_2314|M.vanbaalenii_PYR-1 EDVEEALPSRPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKRNA MAB_3131c|M.abscessus_ATCC_199 EDVEEALPSRPVQVIGFTSVPGAGDNLLVVDEDRIARQIADRRSARKRNA MLBr_01556|M.leprae_Br4923 VDIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKRNA MUL_2318|M.ulcerans_Agy99 VGAAAGPVPAGAHSAPAAIPAAPGAHVMTGAGRPAELSAPHGGVPHGLGD MMAR_5464|M.marinum_M TPAALDEV-----------------------------GGAPGASAPGEYH MAV_4644|M.avium_104 VPPHFPDTPTHGLG----------------------DGGAHGPPESDPKN Mb3933c|M.bovis_AF2122/97 EPPGLHAPHR---------------------------EQQLAMHSNEPAG Rv3903c|M.tuberculosis_H37Rv EPPGLHAPHR---------------------------EQQLAMHSNEPAG MSMEG_1870|M.smegmatis_MC2_155 VGGEHSAISSDSNIGSAEHHRPVTDESRNWADEQAHRPAEQQPAHNAAAE TH_3868|M.thermoresistible__bu -------------------------------------------------- Mflv_4039|M.gilvum_PYR-GCK LAARTRKRIS---------------------------LEDLDSALKETSQ Mvan_2314|M.vanbaalenii_PYR-1 LAARTRKRIS---------------------------LEDLDSALKETSQ MAB_3131c|M.abscessus_ATCC_199 LAARSRKRIS---------------------------LDDLDAALKETSQ MLBr_01556|M.leprae_Br4923 LAARSRKRIS---------------------------LEDLDSALKETSQ MUL_2318|M.ulcerans_Agy99 AGPSGGHPHG-------------------------------LPPHGGGPH MMAR_5464|M.marinum_M GTGGGPGDHGTADGGQSLIIVDGLHAD---DLSALADYTGSGYLDLNNAL MAV_4644|M.avium_104 ANGHGPHDASLDSGSDHHLPLHPLDSD---DLAALAHYTGPGYQELNFAL Mb3933c|M.bovis_AF2122/97 EGWHRLSDEAVDPQYGEPLSRHWDFTDNPADRSRINPVVAQLMEDPNAPF Rv3903c|M.tuberculosis_H37Rv EGWHRLSDEAVDPQYGEPLSRHWDFTDNPADRSRINPVVAQLMEDPNAPF MSMEG_1870|M.smegmatis_MC2_155 QPVTHDRNSAETNESREPAYSSAVNGPQPAMGPMMSPGVGSGPGSPMTPH TH_3868|M.thermoresistible__bu -------------------------------------------------- Mflv_4039|M.gilvum_PYR-GCK LNLILKGDNSGTVEALEEALLGIQVDDEVQLRVIDRGVGGVTETNVNLAS Mvan_2314|M.vanbaalenii_PYR-1 LNLILKGDNSGTVEALEEALLGIQVDDEVELRVIDRGVGGVTETNVNLAS MAB_3131c|M.abscessus_ATCC_199 LNLILKGDNAGTVEALEEALLGIAIDDEVQLRVIDRGVGGVTETNVNLAS MLBr_01556|M.leprae_Br4923 LNLILKGDNAGTVEALEEALMGIQVDDEVALRVIDRGVGGITETNVNLAS MUL_2318|M.ulcerans_Agy99 GPGDASHGARHAEPPRDGTAHGTADGGDAHGDDVSGHGLSAEKRDEIIAM MMAR_5464|M.marinum_M RSDILDASLNAR--------VAALNSALQKLPTYDGTVVRGTDLPPEVVA MAV_4644|M.avium_104 REGALDVSQQAR--------VDALQKALEKLPVYEGAVVRGTNLPADVLE Mb3933c|M.bovis_AF2122/97 GRDPQGQPYTQERYQERFNSVGPWGQQYSNFPPNNGAVP-GTRIAYTNLE Rv3903c|M.tuberculosis_H37Rv GRDPQGQPYTQERYQERFNSVGPWGQQYSNFPPNNGAVP-GTRIAYTNLE MSMEG_1870|M.smegmatis_MC2_155 APGPVHGGGESPSPAAKLPTPDTSTRGPETRPSHTGSPETPRAQQPSAVG TH_3868|M.thermoresistible__bu -------------------------------------------------- Mflv_4039|M.gilvum_PYR-GCK ASDAIIIGFNVRAEGKATELANREGVEIRYYSIIYQAIDEIESALKGMLK Mvan_2314|M.vanbaalenii_PYR-1 ASDAIIIGFNVRAEGKATELANREGVEIRYYSIIYQAIDEIESALKGMLK MAB_3131c|M.abscessus_ATCC_199 ASDAIIIGFNVRAEGKATELANREGVDIRYYSVIYQAIDEIESALKGMLK MLBr_01556|M.leprae_Br4923 ASDAIIIGFNVRAEGKATELASREGVEIRYYLVIYQAIDDIEKALRGMLK MUL_2318|M.ulcerans_Agy99 RKGSRPDPSEYLSPEYIQGHLDRFTGGATRFMPESNLDKYGIAQRDGTSF MMAR_5464|M.marinum_M QYLPGEVITEVAFLSTTTDPAVAQSPTFAGNVEFRIVSRTGR----DVSS MAV_4644|M.avium_104 QYRPGEVITEAAFTSTSTDHTVAQSSAFAGNTEFRIWSTTGR----DVSS Mb3933c|M.bovis_AF2122/97 KFLSDYGPQLDRIGGDQGKYLAIMEHGRPASWEQRALHVTSLRDPYHAYT Rv3903c|M.tuberculosis_H37Rv KFLSDYGPQLDRIGGDQGKYLAIMEHGRPASWEQRALHVTSLRDPYHAYT MSMEG_1870|M.smegmatis_MC2_155 PTPGSTPSAPVHSSADQSRQSASTSPASSTSEQTAPKEHGTAPGSSVPPS TH_3868|M.thermoresistible__bu -------------------------------------------------- Mflv_4039|M.gilvum_PYR-GCK PIYEEKELGRAEIRAIFRSSKVGNIAGCLVQSGIMRRNAKARLLRDNVVV Mvan_2314|M.vanbaalenii_PYR-1 PVYEEKELGRAEIRAIFRSSKVGNIAGCLVQSGIMRRNAKARLLRDNVVV MAB_3131c|M.abscessus_ATCC_199 PVYEEVELGRAEIRAMFRSSKVGNIAGCLVTSGIIRRNAKARLLRDNIVV MLBr_01556|M.leprae_Br4923 PIYEENQLGRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVV MUL_2318|M.ulcerans_Agy99 VMPKSE--ADAMIAGTGGDLRLMEEELGLPEGFLDSNQIVRIDIEDPRQF MMAR_5464|M.marinum_M VSMFPD-----EREILFPAG-TKFYVIDKTLDALTG-RTIIDMIER---- MAV_4644|M.avium_104 VSMYPD-----EKEILFPAG-SKFYVVSKTVDPQTG-RTIIEMIER---- Mb3933c|M.bovis_AF2122/97 IDWLPEGWFIEVSEVAPGCGQPGGSIQVRIFDHQNEMRKVEELIRRGVLR Rv3903c|M.tuberculosis_H37Rv IDWLPEGWFIEVSEVAPGCGQPGGSIQVRIFDHQNEMRKVEELIRRGVLR MSMEG_1870|M.smegmatis_MC2_155 DSHHNSPPPKPEPPHDSSGLEPPVHDGDAFTDPAKSDLDYNPMLDENGHY TH_3868|M.thermoresistible__bu -------------------------------------------------- Mflv_4039|M.gilvum_PYR-GCK AQNLTVSSLKREKDDATEVREGYECGLTLTYNDIKEGDVIETYELVEKAR Mvan_2314|M.vanbaalenii_PYR-1 AENLTISSLKREKDDVTEVRDGYECGLTLTYSDIKEGDVIETYELVEKAR MAB_3131c|M.abscessus_ATCC_199 AETVTISSLRREKDDVVEVRDGYECGLTLTYNDIKEGDVIEAYELREKER MLBr_01556|M.leprae_Br4923 TDNLTVTSLRREKDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQR MUL_2318|M.ulcerans_Agy99 NLRIPSGNEAGANEQWIPGGLLPTGASEAVVDGGKVPQGDYTVTDVFEEK MMAR_5464|M.marinum_M -------------------------------------------------- MAV_4644|M.avium_104 -------------------------------------------------- Mb3933c|M.bovis_AF2122/97 Q------------------------------------------------- Rv3903c|M.tuberculosis_H37Rv Q------------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 VPGSLPSYDELLRLTRTEPDSAHYWSGRDANGVGVGPDGSGIAERIAEGS TH_3868|M.thermoresistible__bu -------------------------------------------------- Mflv_4039|M.gilvum_PYR-GCK T------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 T------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 V------------------------------------------------- MLBr_01556|M.leprae_Br4923 A------------------------------------------------- MUL_2318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5464|M.marinum_M -------------------------------------------------- MAV_4644|M.avium_104 -------------------------------------------------- Mb3933c|M.bovis_AF2122/97 -------------------------------------------------- Rv3903c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 NGTTLEMTLERNGVHPLPAWNRHDPESVRFWEDASAAYAENARGDVTAIV TH_3868|M.thermoresistible__bu -------------------------------------------------- Mflv_4039|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5464|M.marinum_M -------------------------------------------------- MAV_4644|M.avium_104 -------------------------------------------------- Mb3933c|M.bovis_AF2122/97 -------------------------------------------------- Rv3903c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 GSDLRPGNIWQTVEIPRLMDNPNVTRIVQIDPDTGRATELFHRTTSADGP TH_3868|M.thermoresistible__bu -------------------------------------------------- Mflv_4039|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5464|M.marinum_M -------------------------------------------------- MAV_4644|M.avium_104 -------------------------------------------------- Mb3933c|M.bovis_AF2122/97 -------------------------------------------------- Rv3903c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 APNGQMEPTARHDGLTSETDSRTLRDTDQDSIDRASNKPDADVRAEPSHS TH_3868|M.thermoresistible__bu -------------------------------------------------- Mflv_4039|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5464|M.marinum_M -------------------------------------------------- MAV_4644|M.avium_104 -------------------------------------------------- Mb3933c|M.bovis_AF2122/97 -------------------------------------------------- Rv3903c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 WRDDTDQQRGDDRGYSDDDGPRENAVGPDGRYKISGHGDYHSGDGTFTVP TH_3868|M.thermoresistible__bu -------------------------------------------------- Mflv_4039|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5464|M.marinum_M -------------------------------------------------- MAV_4644|M.avium_104 -------------------------------------------------- Mb3933c|M.bovis_AF2122/97 -------------------------------------------------- Rv3903c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 ADTSVTVYGEHGSPITQSLGNLIESGGDTSRVFKKTYYPGETMPNYTLLP TH_3868|M.thermoresistible__bu -------------------------------------------------- Mflv_4039|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5464|M.marinum_M -------------------------------------------------- MAV_4644|M.avium_104 -------------------------------------------------- Mb3933c|M.bovis_AF2122/97 -------------------------------------------------- Rv3903c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_1870|M.smegmatis_MC2_155 PDDMNIVGTPHTVDRATTLSDLLQPNMGAVDFVACLGSWNHRVFDVHGIY TH_3868|M.thermoresistible__bu -------------------------------------------------- Mflv_4039|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2314|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MUL_2318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_5464|M.marinum_M ------------------------ MAV_4644|M.avium_104 ------------------------ Mb3933c|M.bovis_AF2122/97 ------------------------ Rv3903c|M.tuberculosis_H37Rv ------------------------ MSMEG_1870|M.smegmatis_MC2_155 HQDTYDFIEKYPWPEPENLGDDDW TH_3868|M.thermoresistible__bu ------------------------ Mflv_4039|M.gilvum_PYR-GCK ------------------------ Mvan_2314|M.vanbaalenii_PYR-1 ------------------------ MAB_3131c|M.abscessus_ATCC_199 ------------------------ MLBr_01556|M.leprae_Br4923 ------------------------ MUL_2318|M.ulcerans_Agy99 ------------------------