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MTGQITVTKLGSRIGARVDGVRLGGDLDDATVEQIRRALLTHKVIFFRHQHHLDDSRQLEFARLLGTPIG HPAASALAAKHLPVITPIDSEYGKATRWHTDVTFAANYPAASILRAVTLPSYGGSTLWASTVAAYQQLPE PLRHLTENLWALHTNRYDYVRNDPMNDTQRAFRQAFEKPDFRTEHPVVRVHPETGERALLAGDFVRGFVG LDGHESSVLLELLQRRITMPENTVRWSWAPGDVAMWDNRATQHRAIDDYDDQPRLMHRITLMGDVPVNVH GERSRVISGAPLEVLAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4353 | - | - | 100% (297) | alpha-ketoglutarate-dependent taurine dioxygenase |
| M. avium 104 | MAV_0235 | - | 4e-25 | 33.73% (252) | taurine catabolism dioxygenase TauD/TfdA |
| M. avium 104 | MAV_3959 | - | 2e-23 | 31.21% (282) | taurine catabolism dioxygenase TauD, TfdA family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3440 | - | 1e-138 | 79.59% (294) | dioxygenase |
| M. gilvum PYR-GCK | Mflv_3107 | - | 3e-97 | 60.90% (289) | taurine dioxygenase |
| M. tuberculosis H37Rv | Rv3406 | - | 1e-138 | 79.59% (294) | dioxygenase |
| M. leprae Br4923 | MLBr_01992 | - | 6e-10 | 20.98% (286) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0086 | - | 2e-89 | 54.85% (299) | putative taurine dioxygenase |
| M. marinum M | MMAR_1141 | tauD | 1e-136 | 79.32% (295) | taurine catabolism dioxygenase, TauD |
| M. smegmatis MC2 155 | MSMEG_3870 | - | 1e-103 | 64.46% (287) | alpha-ketoglutarate-dependent taurine dioxygenase |
| M. thermoresistible (build 8) | TH_0024 | - | 2e-24 | 31.10% (283) | dioxygenase, TauD/TfdA family protein |
| M. ulcerans Agy99 | MUL_0904 | tauD | 1e-136 | 79.32% (295) | taurine catabolism dioxygenase, TauD |
| M. vanbaalenii PYR-1 | Mvan_4182 | - | 8e-25 | 32.04% (284) | taurine catabolism dioxygenase TauD/TfdA |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3440|M.bovis_AF2122/97 MTDLITVKKLGSRIGAQIDGVRLGGDLDPAAVNEIRAALLAHKVVFFRGQ
Rv3406|M.tuberculosis_H37Rv MTDLITVKKLGSRIGAQIDGVRLGGDLDPAAVNEIRAALLAHKVVFFRGQ
MMAR_1141|M.marinum_M MTDLITVKKLGSRIGAQVDGVSLGADLDAAAVDQIRAALLEHKVIFFRNQ
MUL_0904|M.ulcerans_Agy99 MTDLITVKKLGSRIGAQVDGVSLGADLDAAAVDQIRAALLEHKVIFFRNQ
MAV_4353|M.avium_104 MTGQITVTKLGSRIGARVDGVRLGGDLDDATVEQIRRALLTHKVIFFRHQ
Mflv_3107|M.gilvum_PYR-GCK -MSSPDVVKLGAAIGARIDGVDLARGIDAGTAAQINAALLEHKVIFFRGQ
MSMEG_3870|M.smegmatis_MC2_155 --MQVTVTKLGAHIGARIDGVRVGGDLSPATVSAINAALLEHKVIFFSGQ
MAB_0086|M.abscessus_ATCC_1997 MSSDLRVVKLGENIGARIDGVRLG-EVDTATASAINEAMLEHKVVFFRGQ
TH_0024|M.thermoresistible__bu -MSRLTINRLTASVGAEVTGTTADELAADAALGAAVLDALEEHGVLVFRG
Mvan_4182|M.vanbaalenii_PYR-1 -MTLLTINKLTSSVGAEVTGLDPGRLAGDDALGTAVLDALEDNGVLVFPG
MLBr_01992|M.leprae_Br4923 ----MTLDVKGDGLGAQVTGVDPK-NLDSISTAEIRKIVYVNKLVVLK-D
: :**.: * : .: :..
Mb3440|M.bovis_AF2122/97 HQLDDAEQLAFAGLLGTP-IGHPAAIALAD-DAPIITPINSE---FGKAN
Rv3406|M.tuberculosis_H37Rv HQLDDAEQLAFAGLLGTP-IGHPAAIALAD-DAPIITPINSE---FGKAN
MMAR_1141|M.marinum_M HHLDDQQQLQFAGLLGTP-IGHPAAAAALP-DAPIITPINSE---WGKAN
MUL_0904|M.ulcerans_Agy99 HHLDDQQQLQFAGLLGTP-IGHPAAAAALP-DAPIITPINSE---WGKAN
MAV_4353|M.avium_104 HHLDDSRQLEFARLLGTP-IGHPAASALAAKHLPVITPIDSE---YGKAT
Mflv_3107|M.gilvum_PYR-GCK HDLDDDGQLEFARALGTPTTAHPTVTSRGA----KVLPIDSR---YDKAD
MSMEG_3870|M.smegmatis_MC2_155 DHLDDAGQLEFAELLGTPTVAHPTLAEGAE----QLLPIDSR---YDKAN
MAB_0086|M.abscessus_ATCC_1997 HHVDDEVQFAFAKSMGIPTTPHPTLTSSDV----KVLPIDSEE--GGRAN
TH_0024|M.thermoresistible__bu LRIDPQTQVKFCRHLGEVDHSSDGHHPVAG-----IYPVTLDK--SKNSS
Mvan_4182|M.vanbaalenii_PYR-1 LHLEPEVQVEFCRRLGEIDFSSDGHHRVAG-----IYPVTLDK--SKNSS
MLBr_01992|M.leprae_Br4923 VHPTPEEFIKLGRIIGEIVPYYEPIYRHKDYPEIFVSSTEEGQGVPNTGA
. : :* : . .
Mb3440|M.bovis_AF2122/97 RWHTDVTFAANYP-----------AASVLRAVSLPSYGGSTLWANTAAAY
Rv3406|M.tuberculosis_H37Rv RWHTDVTFAANYP-----------AASVLRAVSLPSYGGSTLWANTAAAY
MMAR_1141|M.marinum_M RWHTDVTFAANYP-----------AASILRAVTLPNYGGSTLWANTATAY
MUL_0904|M.ulcerans_Agy99 RWHTDVTFAANYP-----------AASILRAVTLPNYGGSTLWANTATAY
MAV_4353|M.avium_104 RWHTDVTFAANYP-----------AASILRAVTLPSYGGSTLWASTVAAY
Mflv_3107|M.gilvum_PYR-GCK SWHTDVTFVDRIP-----------KASLLRAVTLPAYGGTTAWASTEAAY
MSMEG_3870|M.smegmatis_MC2_155 SWHTDVTFVDRIP-----------KASLLRAVTLPSYGGTTAWASTEAAY
MAB_0086|M.abscessus_ATCC_1997 QWHTDVTFVDRIP-----------KASILRAVELPPYGGTTTWTSTVAAY
TH_0024|M.thermoresistible__bu AAYLRATFDWHIDGCTPTGDEYPQKATVLSAVQVADRGGETEFASSYGAY
Mvan_4182|M.vanbaalenii_PYR-1 AAYLRATFDWHIDGCTPTGDDYPQMATVLSAKQVAESGGETEFASSYAAY
MLBr_01992|M.leprae_Br4923 FWHVDYIFMPEPF-----------AFSMTLPLAMPGHDRGTHFIDLSQVW
: * . :: . :. . * : . .:
Mb3440|M.bovis_AF2122/97 AELPEPLKCLTENLWALHTNRYDYVT-----TKPLTAAQ---RAFRQVFE
Rv3406|M.tuberculosis_H37Rv AELPEPLKCLTENLWALHTNRYDYVT-----TKPLTAAQ---RAFRQVFE
MMAR_1141|M.marinum_M AELPEPLKCLVENLWALHTNRYDYVANEA--VQALTDTQ---QAFRQAFQ
MUL_0904|M.ulcerans_Agy99 AELPEPLKCLVENLWALHTNRYDYVANEA--VQALTDTQ---QAFRQAFQ
MAV_4353|M.avium_104 QQLPEPLRHLTENLWALHTNRYDYVR-----NDPMNDTQ---RAFRQAFE
Mflv_3107|M.gilvum_PYR-GCK DRLPAPLRALTENLWAVHTNTYDYAADADARLVPLADTE---RQYREEFV
MSMEG_3870|M.smegmatis_MC2_155 QQLPAPLRTLADNLWAVHTNRFDYADSA------ISAEQ---RGYRQRFE
MAB_0086|M.abscessus_ATCC_1997 RQLPKPLQDLADNLWAMHNNQFDYTQVDPAKVAELLAKAGSGSKYVREFG
TH_0024|M.thermoresistible__bu EALSEEEKRHVETLRVVHSLEASQRR--------VTPDP---TPEQLARW
Mvan_4182|M.vanbaalenii_PYR-1 DALTDAEKQRFASLRVVHSLEASQRR--------VNPDP---SPEELARW
MLBr_01992|M.leprae_Br4923 ESLPNAMKDSVRGTYSNHSPRRYIKIRPS---DVYRPVG----EVLAEIE
*. : *.
Mb3440|M.bovis_AF2122/97 KPDFRTEHPVVRVHPETGERTLLAGDFVRSFVG--LDSHESRVLFEVLQR
Rv3406|M.tuberculosis_H37Rv KPDFRTEHPVVRVHPETGERTLLAGDFVRSFVG--LDSHESRVLFEVLQR
MMAR_1141|M.marinum_M KPDFRTEHPVVRVHPETGERTLLAGDFVRGFVG--LDSQESSALFELLQR
MUL_0904|M.ulcerans_Agy99 KPDFRTEHPVVRVHPETGERTLLAGDFVRGFVG--LDSQESSALFELLQR
MAV_4353|M.avium_104 KPDFRTEHPVVRVHPETGERALLAGDFVRGFVG--LDGHESSVLLELLQR
Mflv_3107|M.gilvum_PYR-GCK SDYYETEHPVVRVHPETGRKVLLLGHFVKHFVG--LGQAESTALLQLLQN
MSMEG_3870|M.smegmatis_MC2_155 SDYYEVEHPVVRVHPETGERVLLLGHFVKSFVG--LKDTESAALFRLFQD
MAB_0086|M.abscessus_ATCC_1997 ATHFETHHPVVRVHPETGEKALLLGNFVKRILD--VSASESQALFRMFQD
TH_0024|M.thermoresistible__bu RARPTHEHPLVWTH-RNGRKSLVLGASADYVVG--MDLDEGRALLADLLD
Mvan_4182|M.vanbaalenii_PYR-1 RARPTHEHPLVWTH-RTGRKSLVLGASADYIVG--MDPEEGRALLSELLD
MLBr_01992|M.leprae_Br4923 EVTPPQKWPTVIKHPKTGQEILYICEAATVSVEDKNGNLLDPMVLQELLT
. * * * ..*.. * . : . :: :
Mb3440|M.bovis_AF2122/97 RITMPENTIR------WNWAPGDVAIWDNRATQHRAIDDYDDQHRLMHRV
Rv3406|M.tuberculosis_H37Rv RITMPENTIR------WNWAPGDVAIWDNRATQHRAIDDYDDQHRLMHRV
MMAR_1141|M.marinum_M RITSPENTIR------WNWESGDVAIWDNRATQHRAIDDYDDQHRLLHRV
MUL_0904|M.ulcerans_Agy99 RITSPENTIR------WNWESGDVAIWDNRATQHRAIDDYDDQHRLLHRV
MAV_4353|M.avium_104 RITMPENTVR------WSWAPGDVAMWDNRATQHRAIDDYDDQPRLMHRI
Mflv_3107|M.gilvum_PYR-GCK RVTKLENTIR------WSWELGDIAVWDNRATQHYAVSDYDDQFRRLSRV
MSMEG_3870|M.smegmatis_MC2_155 RITRLENTVR------WSWKPGDLAIWDNRATQHYAVADYDDQYRRLNRV
MAB_0086|M.abscessus_ATCC_1997 RVTWLENTIR------WSWELGDVAMWDNRATQHYAISDYGDQPRRMHRV
TH_0024|M.thermoresistible__bu RATTEDRVYR------HRWSVGDTVIWDNRGVLHRAAPYPEDSPREMLRT
Mvan_4182|M.vanbaalenii_PYR-1 RATTADKVYS------HHWAVGDTVIWDNRGVLHRAARYDENSPREMLRT
MLBr_01992|M.leprae_Br4923 ASGQLDPDCKSLLIHTQHYEVGDVVLWDNRALVHRAKHGTVSGTLITYRL
: : ** .:****. * * . *
Mb3440|M.bovis_AF2122/97 TLMGDVPVDVYGQASRVISG---------APMEIAG---
Rv3406|M.tuberculosis_H37Rv TLMGDVPVDVYGQASRVISG---------APMEIAG---
MMAR_1141|M.marinum_M TLMGDVPVDVHGQRSRVISG---------APLALAG---
MUL_0904|M.ulcerans_Agy99 TLMGDVPVDVHGQRSRVISG---------APLALAG---
MAV_4353|M.avium_104 TLMGDVPVNVHGERSRVISG---------APLEVLAS--
Mflv_3107|M.gilvum_PYR-GCK TLAGDIPVDVYGRRSRVIAGDASTYSQVVVPLKLAGLAS
MSMEG_3870|M.smegmatis_MC2_155 TLAGDIPVDVYGERSRVIAGDASSYSPVDSPVALAS---
MAB_0086|M.abscessus_ATCC_1997 TLAGDVPVGVNGESSRVIAGDASDYSVIDNPKRLVA---
TH_0024|M.thermoresistible__bu TVLGDEPIQ------------------------------
Mvan_4182|M.vanbaalenii_PYR-1 TVLGDEPIQ------------------------------
MLBr_01992|M.leprae_Br4923 TLLDGLKTPGYAV--------------------------
*: ..