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M. marinum M MMAR_1141 (tauD)

annotation: taurine catabolism dioxygenase, TauD
coordinates: 1369822 - 1370718
length: 298

TDLITVKKLGSRIGAQVDGVSLGADLDAAAVDQIRAALLEHKVIFFRNQHHLDDQQQLQFAGLLGTPIGH
PAAAAALPDAPIITPINSEWGKANRWHTDVTFAANYPAASILRAVTLPNYGGSTLWANTATAYAELPEPL
KCLVENLWALHTNRYDYVANEAVQALTDTQQAFRQAFQKPDFRTEHPVVRVHPETGERTLLAGDFVRGFV
GLDSQESSALFELLQRRITSPENTIRWNWESGDVAIWDNRATQHRAIDDYDDQHRLLHRVTLMGDVPVDV
HGQRSRVISGAPLALAG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_1141tauD-100% (298)taurine catabolism dioxygenase, TauD
M. marinum MMMAR_0260-9e-0822.14% (271) oxidoreductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3440-1e-14683.56% (298) dioxygenase
M. gilvum PYR-GCKMflv_3107-8e-9657.57% (304) taurine dioxygenase
M. tuberculosis H37RvRv3406-1e-14683.56% (298) dioxygenase
M. leprae Br4923MLBr_01992-3e-1121.68% (286) putative oxidoreductase
M. abscessus ATCC 19977MAB_4209c-9e-8555.02% (289) putative dioxygenase
M. avium 104MAV_4353-1e-13679.32% (295) alpha-ketoglutarate-dependent taurine dioxygenase
M. smegmatis MC2 155MSMEG_3870-7e-9959.08% (303) alpha-ketoglutarate-dependent taurine dioxygenase
M. thermoresistible (build 8)TH_0024-2e-2332.08% (293) dioxygenase, TauD/TfdA family protein
M. ulcerans Agy99MUL_0904tauD1e-175100.00% (298) taurine catabolism dioxygenase, TauD
M. vanbaalenii PYR-1Mvan_4182-1e-1928.97% (290) taurine catabolism dioxygenase TauD/TfdA

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1141|M.marinum_M               ----------MTDLITVKKLGSRIGAQVDGVSLG-ADLDAAAVDQIRAAL
MUL_0904|M.ulcerans_Agy99           ----------MTDLITVKKLGSRIGAQVDGVSLG-ADLDAAAVDQIRAAL
Mb3440|M.bovis_AF2122/97            ----------MTDLITVKKLGSRIGAQIDGVRLG-GDLDPAAVNEIRAAL
Rv3406|M.tuberculosis_H37Rv         ----------MTDLITVKKLGSRIGAQIDGVRLG-GDLDPAAVNEIRAAL
MAV_4353|M.avium_104                ----------MTGQITVTKLGSRIGARVDGVRLG-GDLDDATVEQIRRAL
Mflv_3107|M.gilvum_PYR-GCK          -----------MSSPDVVKLGAAIGARIDGVDLA-RGIDAGTAAQINAAL
MSMEG_3870|M.smegmatis_MC2_155      ------------MQVTVTKLGAHIGARIDGVRVG-GDLSPATVSAINAAL
MAB_4209c|M.abscessus_ATCC_199      MTDDQTRRIYRDAGITVEKLGEHIGARVNGIELR-GDLSADRVEAIRLAL
TH_0024|M.thermoresistible__bu      -----------MSRLTINRLTASVGAEVTGTTADELAADAALGAAVLDAL
Mvan_4182|M.vanbaalenii_PYR-1       -----------MTLLTINKLTSSVGAEVTGLDPGRLAGDDALGTAVLDAL
MLBr_01992|M.leprae_Br4923          --------------MTLDVKGDGLGAQVTGVDPK--NLDSISTAEIRKIV
                                                    :      :**.: *        .      :   :

MMAR_1141|M.marinum_M               LEHKVIFFRNQHHLDDQQQLQFAGLLGTP-----IGHPAAAAALP-DAPI
MUL_0904|M.ulcerans_Agy99           LEHKVIFFRNQHHLDDQQQLQFAGLLGTP-----IGHPAAAAALP-DAPI
Mb3440|M.bovis_AF2122/97            LAHKVVFFRGQHQLDDAEQLAFAGLLGTP-----IGHPAAIALAD-DAPI
Rv3406|M.tuberculosis_H37Rv         LAHKVVFFRGQHQLDDAEQLAFAGLLGTP-----IGHPAAIALAD-DAPI
MAV_4353|M.avium_104                LTHKVIFFRHQHHLDDSRQLEFARLLGTP-----IGHPAASALAAKHLPV
Mflv_3107|M.gilvum_PYR-GCK          LEHKVIFFRGQHDLDDDGQLEFARALGTPT----TAHPTVTSRGA----K
MSMEG_3870|M.smegmatis_MC2_155      LEHKVIFFSGQDHLDDAGQLEFAELLGTPT----VAHPTLAEGAE----Q
MAB_4209c|M.abscessus_ATCC_199      AINKVLVFTEQHHLDDAGQYAFARLLGEPT----LPHPTVRSHGT----E
TH_0024|M.thermoresistible__bu      EEHGVLVFRG-LRIDPQTQVKFCRHLGEVDHSSDGHHPVAGIYPVTLDKS
Mvan_4182|M.vanbaalenii_PYR-1       EDNGVLVFPG-LHLEPEVQVEFCRRLGEIDFSSDGHHRVAGIYPVTLDKS
MLBr_01992|M.leprae_Br4923          YVNKLVVLKD-VHPTPEEFIKLGRIIGEIVP-YYEPIYRHKDYPEIFVSS
                                      : ::.:             :   :*                       

MMAR_1141|M.marinum_M               ITPINSEWGKANRWHTD---VTFAANYPAASILRAVTLPNYGGSTLWANT
MUL_0904|M.ulcerans_Agy99           ITPINSEWGKANRWHTD---VTFAANYPAASILRAVTLPNYGGSTLWANT
Mb3440|M.bovis_AF2122/97            ITPINSEFGKANRWHTD---VTFAANYPAASVLRAVSLPSYGGSTLWANT
Rv3406|M.tuberculosis_H37Rv         ITPINSEFGKANRWHTD---VTFAANYPAASVLRAVSLPSYGGSTLWANT
MAV_4353|M.avium_104                ITPIDSEYGKATRWHTD---VTFAANYPAASILRAVTLPSYGGSTLWAST
Mflv_3107|M.gilvum_PYR-GCK          VLPIDSRYDKADSWHTD---VTFVDRIPKASLLRAVTLPAYGGTTAWAST
MSMEG_3870|M.smegmatis_MC2_155      LLPIDSRYDKANSWHTD---VTFVDRIPKASLLRAVTLPSYGGTTAWAST
MAB_4209c|M.abscessus_ATCC_199      LLNLEG---AANGWHTD---VTFVDRIPKASVLRPVTLPSYGGATTWAST
TH_0024|M.thermoresistible__bu      KNSSAAYLRATFDWHIDGCTPTGDEYPQKATVLSAVQVADRGGETEFASS
Mvan_4182|M.vanbaalenii_PYR-1       KNSSAAYLRATFDWHIDGCTPTGDDYPQMATVLSAKQVAESGGETEFASS
MLBr_01992|M.leprae_Br4923          TEEGQGVPNTGAFWHVD---YIFMPEPFAFSMTLPLAMPGHDRGTHFIDL
                                         .       ** *             ::  .  :.  .  * : . 

MMAR_1141|M.marinum_M               ATAYAELPEPLKCLVENLWALHTNRYDYVANEA--VQALTDTQQA-FRQA
MUL_0904|M.ulcerans_Agy99           ATAYAELPEPLKCLVENLWALHTNRYDYVANEA--VQALTDTQQA-FRQA
Mb3440|M.bovis_AF2122/97            AAAYAELPEPLKCLTENLWALHTNRYDYVT-----TKPLTAAQRA-FRQV
Rv3406|M.tuberculosis_H37Rv         AAAYAELPEPLKCLTENLWALHTNRYDYVT-----TKPLTAAQRA-FRQV
MAV_4353|M.avium_104                VAAYQQLPEPLRHLTENLWALHTNRYDYVR-----NDPMNDTQRA-FRQA
Mflv_3107|M.gilvum_PYR-GCK          EAAYDRLPAPLRALTENLWAVHTNTYDYAADADARLVPLADTERQ-YREE
MSMEG_3870|M.smegmatis_MC2_155      EAAYQQLPAPLRTLADNLWAVHTNRFDYADSA------ISAEQRG-YRQR
MAB_4209c|M.abscessus_ATCC_199      VAAYEQLPKPLRSLVDDLWATHTNLYDYASSGASG--GVSAERRAAYYTE
TH_0024|M.thermoresistible__bu      YGAYEALSEEEKRHVETLRVVHSLEASQRR--------VTPDPTP-EQLA
Mvan_4182|M.vanbaalenii_PYR-1       YAAYDALTDAEKQRFASLRVVHSLEASQRR--------VNPDPSP-EELA
MLBr_01992|M.leprae_Br4923          SQVWESLPNAMKDSVRGTYSNHSPRRYIKIRPS-----DVYRPVGEVLAE
                                      .:  *.   :         *:                           

MMAR_1141|M.marinum_M               FQKPDFRTEHPVVRVHPETGERTLLAGDFVRGFVG--LDSQESSALFELL
MUL_0904|M.ulcerans_Agy99           FQKPDFRTEHPVVRVHPETGERTLLAGDFVRGFVG--LDSQESSALFELL
Mb3440|M.bovis_AF2122/97            FEKPDFRTEHPVVRVHPETGERTLLAGDFVRSFVG--LDSHESRVLFEVL
Rv3406|M.tuberculosis_H37Rv         FEKPDFRTEHPVVRVHPETGERTLLAGDFVRSFVG--LDSHESRVLFEVL
MAV_4353|M.avium_104                FEKPDFRTEHPVVRVHPETGERALLAGDFVRGFVG--LDGHESSVLLELL
Mflv_3107|M.gilvum_PYR-GCK          FVSDYYETEHPVVRVHPETGRKVLLLGHFVKHFVG--LGQAESTALLQLL
MSMEG_3870|M.smegmatis_MC2_155      FESDYYEVEHPVVRVHPETGERVLLLGHFVKSFVG--LKDTESAALFRLF
MAB_4209c|M.abscessus_ATCC_199      FTSSRYETVHPVVRVHPETGERSLLLGQFVKSFQD--LPSAEFASLFQLL
TH_0024|M.thermoresistible__bu      RWRARPTHEHPLVWTH-RNGRKSLVLGASADYVVG--MDLDEGRALLADL
Mvan_4182|M.vanbaalenii_PYR-1       RWRARPTHEHPLVWTH-RTGRKSLVLGASADYIVG--MDPEEGRALLSEL
MLBr_01992|M.leprae_Br4923          IEEVTPPQKWPTVIKHPKTGQEILYICEAATVSVEDKNGNLLDPMVLQEL
                                              * *  * ..*.. *     .               ::  :

MMAR_1141|M.marinum_M               QRRITSPENTIR------WNWESGDVAIWDNRATQHRAIDDYDDQHRLLH
MUL_0904|M.ulcerans_Agy99           QRRITSPENTIR------WNWESGDVAIWDNRATQHRAIDDYDDQHRLLH
Mb3440|M.bovis_AF2122/97            QRRITMPENTIR------WNWAPGDVAIWDNRATQHRAIDDYDDQHRLMH
Rv3406|M.tuberculosis_H37Rv         QRRITMPENTIR------WNWAPGDVAIWDNRATQHRAIDDYDDQHRLMH
MAV_4353|M.avium_104                QRRITMPENTVR------WSWAPGDVAMWDNRATQHRAIDDYDDQPRLMH
Mflv_3107|M.gilvum_PYR-GCK          QNRVTKLENTIR------WSWELGDIAVWDNRATQHYAVSDYDDQFRRLS
MSMEG_3870|M.smegmatis_MC2_155      QDRITRLENTVR------WSWKPGDLAIWDNRATQHYAVADYDDQYRRLN
MAB_4209c|M.abscessus_ATCC_199      QARITKLENTFR------WNWRLGDVAIWDNRATQHYGIADFGEQQRELH
TH_0024|M.thermoresistible__bu      LDRATTEDRVYR------HRWSVGDTVIWDNRGVLHRAAPYPEDSPREML
Mvan_4182|M.vanbaalenii_PYR-1       LDRATTADKVYS------HHWAVGDTVIWDNRGVLHRAARYDENSPREML
MLBr_01992|M.leprae_Br4923          LTASGQLDPDCKSLLIHTQHYEVGDVVLWDNRALVHRAKHGTVSGTLITY
                                           :            :  ** .:****.  * .     .      

MMAR_1141|M.marinum_M               RVTLMGDVPVDVHGQRSRVISG---------APLALAG---
MUL_0904|M.ulcerans_Agy99           RVTLMGDVPVDVHGQRSRVISG---------APLALAG---
Mb3440|M.bovis_AF2122/97            RVTLMGDVPVDVYGQASRVISG---------APMEIAG---
Rv3406|M.tuberculosis_H37Rv         RVTLMGDVPVDVYGQASRVISG---------APMEIAG---
MAV_4353|M.avium_104                RITLMGDVPVNVHGERSRVISG---------APLEVLAS--
Mflv_3107|M.gilvum_PYR-GCK          RVTLAGDIPVDVYGRRSRVIAGDASTYSQVVVPLKLAGLAS
MSMEG_3870|M.smegmatis_MC2_155      RVTLAGDIPVDVYGERSRVIAGDASSYSPVDSPVALAS---
MAB_4209c|M.abscessus_ATCC_199      RVTLAGDVPVDVHGRRSQILLGDASHYSGIETPQRLELFAA
TH_0024|M.thermoresistible__bu      RTTVLGDEPIQ------------------------------
Mvan_4182|M.vanbaalenii_PYR-1       RTTVLGDEPIQ------------------------------
MLBr_01992|M.leprae_Br4923          RLTLLDGLKTPGYAV--------------------------
                                    * *: ..