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VQVTVTKLGAHIGARIDGVRVGGDLSPATVSAINAALLEHKVIFFSGQDHLDDAGQLEFAELLGTPTVAH PTLAEGAEQLLPIDSRYDKANSWHTDVTFVDRIPKASLLRAVTLPSYGGTTAWASTEAAYQQLPAPLRTL ADNLWAVHTNRFDYADSAISAEQRGYRQRFESDYYEVEHPVVRVHPETGERVLLLGHFVKSFVGLKDTES AALFRLFQDRITRLENTVRWSWKPGDLAIWDNRATQHYAVADYDDQYRRLNRVTLAGDIPVDVYGERSRV IAGDASSYSPVDSPVALAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3870 | - | - | 100% (299) | alpha-ketoglutarate-dependent taurine dioxygenase |
| M. smegmatis MC2 155 | MSMEG_0181 | - | 2e-28 | 33.57% (277) | alpha-ketoglutarate-dependent taurine dioxygenase |
| M. smegmatis MC2 155 | MSMEG_0291 | - | 2e-17 | 29.97% (287) | dioxygenase, TauD/TfdA family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3440 | - | 1e-102 | 63.16% (285) | dioxygenase |
| M. gilvum PYR-GCK | Mflv_3107 | - | 1e-125 | 72.00% (300) | taurine dioxygenase |
| M. tuberculosis H37Rv | Rv3406 | - | 1e-102 | 63.16% (285) | dioxygenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0086 | - | 1e-105 | 61.97% (305) | putative taurine dioxygenase |
| M. marinum M | MMAR_1141 | tauD | 7e-99 | 59.08% (303) | taurine catabolism dioxygenase, TauD |
| M. avium 104 | MAV_4353 | - | 1e-103 | 64.46% (287) | alpha-ketoglutarate-dependent taurine dioxygenase |
| M. thermoresistible (build 8) | TH_0024 | - | 3e-19 | 28.62% (290) | dioxygenase, TauD/TfdA family protein |
| M. ulcerans Agy99 | MUL_0904 | tauD | 5e-99 | 59.08% (303) | taurine catabolism dioxygenase, TauD |
| M. vanbaalenii PYR-1 | Mvan_4182 | - | 6e-18 | 28.97% (290) | taurine catabolism dioxygenase TauD/TfdA |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3870|M.smegmatis_MC2_155 --MQVTVTKLGAHIGARIDGVRVGGDLSPATVSAINAALLEHKVIFFSGQ
Mflv_3107|M.gilvum_PYR-GCK -MSSPDVVKLGAAIGARIDGVDLARGIDAGTAAQINAALLEHKVIFFRGQ
MAB_0086|M.abscessus_ATCC_1997 MSSDLRVVKLGENIGARIDGVRLG-EVDTATASAINEAMLEHKVVFFRGQ
Mb3440|M.bovis_AF2122/97 MTDLITVKKLGSRIGAQIDGVRLGGDLDPAAVNEIRAALLAHKVVFFRGQ
Rv3406|M.tuberculosis_H37Rv MTDLITVKKLGSRIGAQIDGVRLGGDLDPAAVNEIRAALLAHKVVFFRGQ
MMAR_1141|M.marinum_M MTDLITVKKLGSRIGAQVDGVSLGADLDAAAVDQIRAALLEHKVIFFRNQ
MUL_0904|M.ulcerans_Agy99 MTDLITVKKLGSRIGAQVDGVSLGADLDAAAVDQIRAALLEHKVIFFRNQ
MAV_4353|M.avium_104 MTGQITVTKLGSRIGARVDGVRLGGDLDDATVEQIRRALLTHKVIFFRHQ
TH_0024|M.thermoresistible__bu -MSRLTINRLTASVGAEVTGTTADELAADAALGAAVLDALEEHGVLVFRG
Mvan_4182|M.vanbaalenii_PYR-1 -MTLLTINKLTSSVGAEVTGLDPGRLAGDDALGTAVLDALEDNGVLVFPG
: :* :**.: * : * .: ::.
MSMEG_3870|M.smegmatis_MC2_155 DHLDDAGQLEFAELLGTPTVAHPTLAEGAE----QLLPIDSR-YDKANSW
Mflv_3107|M.gilvum_PYR-GCK HDLDDDGQLEFARALGTPTTAHPTVTSRGA----KVLPIDSR-YDKADSW
MAB_0086|M.abscessus_ATCC_1997 HHVDDEVQFAFAKSMGIPTTPHPTLTSSDV----KVLPIDSEEGGRANQW
Mb3440|M.bovis_AF2122/97 HQLDDAEQLAFAGLLGTP-IGHPAAIALAD-DAPIITPINSE-FGKANRW
Rv3406|M.tuberculosis_H37Rv HQLDDAEQLAFAGLLGTP-IGHPAAIALAD-DAPIITPINSE-FGKANRW
MMAR_1141|M.marinum_M HHLDDQQQLQFAGLLGTP-IGHPAAAAALP-DAPIITPINSE-WGKANRW
MUL_0904|M.ulcerans_Agy99 HHLDDQQQLQFAGLLGTP-IGHPAAAAALP-DAPIITPINSE-WGKANRW
MAV_4353|M.avium_104 HHLDDSRQLEFARLLGTP-IGHPAASALAAKHLPVITPIDSE-YGKATRW
TH_0024|M.thermoresistible__bu LRIDPQTQVKFCRHLGEVDHSSDGHHPVAG-----IYPVTLDKSKNSSAA
Mvan_4182|M.vanbaalenii_PYR-1 LHLEPEVQVEFCRRLGEIDFSSDGHHRVAG-----IYPVTLDKSKNSSAA
:: *. *. :* : *: .:
MSMEG_3870|M.smegmatis_MC2_155 HTDVTFVDRIP-----------KASLLRAVTLPSYGGTTAWASTEAAYQQ
Mflv_3107|M.gilvum_PYR-GCK HTDVTFVDRIP-----------KASLLRAVTLPAYGGTTAWASTEAAYDR
MAB_0086|M.abscessus_ATCC_1997 HTDVTFVDRIP-----------KASILRAVELPPYGGTTTWTSTVAAYRQ
Mb3440|M.bovis_AF2122/97 HTDVTFAANYP-----------AASVLRAVSLPSYGGSTLWANTAAAYAE
Rv3406|M.tuberculosis_H37Rv HTDVTFAANYP-----------AASVLRAVSLPSYGGSTLWANTAAAYAE
MMAR_1141|M.marinum_M HTDVTFAANYP-----------AASILRAVTLPNYGGSTLWANTATAYAE
MUL_0904|M.ulcerans_Agy99 HTDVTFAANYP-----------AASILRAVTLPNYGGSTLWANTATAYAE
MAV_4353|M.avium_104 HTDVTFAANYP-----------AASILRAVTLPSYGGSTLWASTVAAYQQ
TH_0024|M.thermoresistible__bu YLRATFDWHIDGCTPTGDEYPQKATVLSAVQVADRGGETEFASSYGAYEA
Mvan_4182|M.vanbaalenii_PYR-1 YLRATFDWHIDGCTPTGDDYPQMATVLSAKQVAESGGETEFASSYAAYDA
: .** . *::* * :. ** * ::.: **
MSMEG_3870|M.smegmatis_MC2_155 LPAPLRTLADNLWAVHTNRFDYADSA------ISAEQ---RGYRQRFESD
Mflv_3107|M.gilvum_PYR-GCK LPAPLRALTENLWAVHTNTYDYAADADARLVPLADTE---RQYREEFVSD
MAB_0086|M.abscessus_ATCC_1997 LPKPLQDLADNLWAMHNNQFDYTQVDPAKVAELLAKAGSGSKYVREFGAT
Mb3440|M.bovis_AF2122/97 LPEPLKCLTENLWALHTNRYDYVT-----TKPLTAAQ---RAFRQVFEKP
Rv3406|M.tuberculosis_H37Rv LPEPLKCLTENLWALHTNRYDYVT-----TKPLTAAQ---RAFRQVFEKP
MMAR_1141|M.marinum_M LPEPLKCLVENLWALHTNRYDYVANEA--VQALTDTQ---QAFRQAFQKP
MUL_0904|M.ulcerans_Agy99 LPEPLKCLVENLWALHTNRYDYVANEA--VQALTDTQ---QAFRQAFQKP
MAV_4353|M.avium_104 LPEPLRHLTENLWALHTNRYDYVR-----NDPMNDTQ---RAFRQAFEKP
TH_0024|M.thermoresistible__bu LSEEEKRHVETLRVVHSLEASQRR--------VTPDP---TPEQLARWRA
Mvan_4182|M.vanbaalenii_PYR-1 LTDAEKQRFASLRVVHSLEASQRR--------VNPDP---SPEELARWRA
*. : .* .:*. . :
MSMEG_3870|M.smegmatis_MC2_155 YYEVEHPVVRVHPETGERVLLLGHFVKSFVGLKDTESAALFRLFQDRITR
Mflv_3107|M.gilvum_PYR-GCK YYETEHPVVRVHPETGRKVLLLGHFVKHFVGLGQAESTALLQLLQNRVTK
MAB_0086|M.abscessus_ATCC_1997 HFETHHPVVRVHPETGEKALLLGNFVKRILDVSASESQALFRMFQDRVTW
Mb3440|M.bovis_AF2122/97 DFRTEHPVVRVHPETGERTLLAGDFVRSFVGLDSHESRVLFEVLQRRITM
Rv3406|M.tuberculosis_H37Rv DFRTEHPVVRVHPETGERTLLAGDFVRSFVGLDSHESRVLFEVLQRRITM
MMAR_1141|M.marinum_M DFRTEHPVVRVHPETGERTLLAGDFVRGFVGLDSQESSALFELLQRRITS
MUL_0904|M.ulcerans_Agy99 DFRTEHPVVRVHPETGERTLLAGDFVRGFVGLDSQESSALFELLQRRITS
MAV_4353|M.avium_104 DFRTEHPVVRVHPETGERALLAGDFVRGFVGLDGHESSVLLELLQRRITM
TH_0024|M.thermoresistible__bu RPTHEHPLVWTH-RNGRKSLVLGASADYVVGMDLDEGRALLADLLDRATT
Mvan_4182|M.vanbaalenii_PYR-1 RPTHEHPLVWTH-RTGRKSLVLGASADYIVGMDPEEGRALLSELLDRATT
.**:* .* ..*.: *: * . .:.: *. .*: : * *
MSMEG_3870|M.smegmatis_MC2_155 LENTVRWSWKPGDLAIWDNRATQHYAVADYDDQYRRLNRVTLAGDIPVDV
Mflv_3107|M.gilvum_PYR-GCK LENTIRWSWELGDIAVWDNRATQHYAVSDYDDQFRRLSRVTLAGDIPVDV
MAB_0086|M.abscessus_ATCC_1997 LENTIRWSWELGDVAMWDNRATQHYAISDYGDQPRRMHRVTLAGDVPVGV
Mb3440|M.bovis_AF2122/97 PENTIRWNWAPGDVAIWDNRATQHRAIDDYDDQHRLMHRVTLMGDVPVDV
Rv3406|M.tuberculosis_H37Rv PENTIRWNWAPGDVAIWDNRATQHRAIDDYDDQHRLMHRVTLMGDVPVDV
MMAR_1141|M.marinum_M PENTIRWNWESGDVAIWDNRATQHRAIDDYDDQHRLLHRVTLMGDVPVDV
MUL_0904|M.ulcerans_Agy99 PENTIRWNWESGDVAIWDNRATQHRAIDDYDDQHRLLHRVTLMGDVPVDV
MAV_4353|M.avium_104 PENTVRWSWAPGDVAMWDNRATQHRAIDDYDDQPRLMHRITLMGDVPVNV
TH_0024|M.thermoresistible__bu EDRVYRHRWSVGDTVIWDNRGVLHRAAPYPEDSPREMLRTTVLGDEPIQ-
Mvan_4182|M.vanbaalenii_PYR-1 ADKVYSHHWAVGDTVIWDNRGVLHRAARYDENSPREMLRTTVLGDEPIQ-
:.. * ** .:****.. * * :. * : * *: ** *:
MSMEG_3870|M.smegmatis_MC2_155 YGERSRVIAGDASSYSPVDSPVALAS---
Mflv_3107|M.gilvum_PYR-GCK YGRRSRVIAGDASTYSQVVVPLKLAGLAS
MAB_0086|M.abscessus_ATCC_1997 NGESSRVIAGDASDYSVIDNPKRLVA---
Mb3440|M.bovis_AF2122/97 YGQASRVISG---------APMEIAG---
Rv3406|M.tuberculosis_H37Rv YGQASRVISG---------APMEIAG---
MMAR_1141|M.marinum_M HGQRSRVISG---------APLALAG---
MUL_0904|M.ulcerans_Agy99 HGQRSRVISG---------APLALAG---
MAV_4353|M.avium_104 HGERSRVISG---------APLEVLAS--
TH_0024|M.thermoresistible__bu -----------------------------
Mvan_4182|M.vanbaalenii_PYR-1 -----------------------------