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NTVHFDFTDAQVLVTGGTSGIGNAIATAFADSGATVTVTGTRAAATDYPDTDLGAFSYRQCHIQDPESVD ALANSLSGLDILVNNAGGPYPAGDEYDPDGYVASVAQNMFGPMRLTMRCHDLLKSSRAAGGASVVNVVSM SAFRSAVFVPGYASSKMGLVALTMNLSRRWAGDGIRVNAIAPGLIDTRMTHPAMGIPEVMDVEIGFHTPL GRPGTPADCAGATLFLCTEAASYITGSTIAVDGGYLTV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4175 | - | - | 100% (249) | oxidoreductase, short chain dehydrogenase/reductase family protein |
| M. avium 104 | MAV_0611 | - | 3e-29 | 34.45% (238) | short chain dehydrogenase |
| M. avium 104 | MAV_0714 | - | 2e-26 | 35.77% (246) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3579c | - | 6e-32 | 34.54% (249) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4818 | - | 5e-31 | 37.60% (250) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv3549c | - | 6e-32 | 34.54% (249) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 7e-20 | 29.72% (249) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0607 | - | 1e-29 | 32.77% (238) | short chain dehydrogenase |
| M. marinum M | MMAR_5288 | - | 1e-64 | 52.07% (242) | short-chain type dehydrogenase/reductase |
| M. smegmatis MC2 155 | MSMEG_1740 | - | 3e-29 | 34.40% (250) | dehydrogenase/reductase SDR family protein member 4 |
| M. thermoresistible (build 8) | TH_2432 | - | 2e-30 | 33.60% (247) | PUTATIVE short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_4361 | - | 8e-64 | 51.65% (242) | short-chain type dehydrogenase/reductase |
| M. vanbaalenii PYR-1 | Mvan_1624 | - | 6e-31 | 36.95% (249) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3579c|M.bovis_AF2122/97 -----MTLAEAADAINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVIT
Rv3549c|M.tuberculosis_H37Rv -----MTLAEAADAINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVIT
TH_2432|M.thermoresistible__bu --------------VNLGLTGRVVLVTGGVRGVGAGISAVFADQGATVVT
MAB_0607|M.abscessus_ATCC_1997 ----------MRTPYDLGLEGRVVLVTGGVRGVGAGISQVFADQGATVVT
MMAR_5288|M.marinum_M ----------MTARVSFDFTGTAALITGGTSGIGHGIAMLFRDAGAQVTV
MUL_4361|M.ulcerans_Agy99 --------------MSFDFTGTAALITGGTSGIGHGIAMLFRDAGAQVTV
MAV_4175|M.avium_104 -----------MNTVHFDFTDAQVLVTGGTSGIGNAIATAFADSGATVTV
Mflv_4818|M.gilvum_PYR-GCK -------MDRASFDRLFDMTDRTVVVTGGTRGIGLALAEGYALAGARVVV
Mvan_1624|M.vanbaalenii_PYR-1 -------MDRASFDRLFDMTDRTVVVTGGTRGIGLALAEGYVLAGARVVV
MSMEG_1740|M.smegmatis_MC2_155 -------MDRQRFERLFDMSDRTVIVTGGTRGIGLSLAEGFVLAGARVVV
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
: . ::*** *:* .:: * * .
Mb3579c|M.bovis_AF2122/97 CARRAVDGQPYEFHRCDIRDEDSVK-----------RLVGEIGERHGRLD
Rv3549c|M.tuberculosis_H37Rv CARRAVDGQPYEFHRCDIRDEDSVK-----------RLVGEIGERHGRLD
TH_2432|M.thermoresistible__bu CARRPVDGLPYEFHSCDVRDDDAVA-----------AMIDTIVDRHGRLD
MAB_0607|M.abscessus_ATCC_1997 CARRPGD-APYEFHSCDVRDEESVD-----------TLIGAIVAAHGRLD
MMAR_5288|M.marinum_M TGTKPGSADY-DTDLSGMTYRQLQLTDPD--------SIAQLTQHFDRLD
MUL_4361|M.ulcerans_Agy99 TGTKPGSADY-DTDLSGMTYRQLQLTDPD--------SIAQLTQHFDRLD
MAV_4175|M.avium_104 TGTRAAATDYPDTDLGAFSYRQCHIQDPE--------SVDALANSLSGLD
Mflv_4818|M.gilvum_PYR-GCK ASRKADACEQAAHHLRELGAQAIGVPTHLGQVDDLGALVERTVAEFGGLD
Mvan_1624|M.vanbaalenii_PYR-1 ASRKADACEETARHLRELGGSAIGVPTHLGEVDDLGALVERTVAEFGGVD
MSMEG_1740|M.smegmatis_MC2_155 ASRKPDACETAAAHLRELGGDAVGVPAHTGDVDDLGAVVERAVSEFGGVD
MLBr_01807|M.leprae_Br4923 THRASVVPDWFFGVECDVTDNDAIG-----------AAFKAVEEHQGPVE
. . . . ::
Mb3579c|M.bovis_AF2122/97 MLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQP--
Rv3549c|M.tuberculosis_H37Rv MLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQP--
TH_2432|M.thermoresistible__bu VVVNNAGGSPYVLTAESSAKFNRKIIELNLLGPLSVSQHANAHMQKQP--
MAB_0607|M.abscessus_ATCC_1997 AVVNNAGGAPFALAADASHNFHRKIIELNLLSALLVSQRANAVMQKQD--
MMAR_5288|M.marinum_M VLVNNAGANFPGGLDESKPDGFDASVQLNLTGPYRLTMGLYRSLKASTAV
MUL_4361|M.ulcerans_Agy99 VLVNNAGANFSGGLDESKPDGFDASVQLNLTGPYRLTMGLYRSLKASTAV
MAV_4175|M.avium_104 ILVNNAGGPYPAG-DEYDPDGYVASVAQNMFGPMRLTMRCHDLLKSSRAA
Mflv_4818|M.gilvum_PYR-GCK VLVNNAANPLAQPFGHMTVDALSKSFEVNLQGPVMLTQEALPHLKAS---
Mvan_1624|M.vanbaalenii_PYR-1 VLVNNAANPLAQPFGYMTVDALTKSFEVNLRGPVMLVQEALPHLKAS---
MSMEG_1740|M.smegmatis_MC2_155 VVVNNAANALAQPLGKMTPEAWAKSYEVNLRGPVFLVQHALPYLQKS---
MLBr_01807|M.leprae_Br4923 VLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR--
:* **. . *: . : : .
Mb3579c|M.bovis_AF2122/97 NGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPK-VRVNA
Rv3549c|M.tuberculosis_H37Rv NGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPK-VRVNA
TH_2432|M.thermoresistible__bu RGGSIINIASVSGRRPTPGTAPYGAAKAGVESLTSTLAVEWAPK-VRVNS
MAB_0607|M.abscessus_ATCC_1997 GGGTIVNITSVSAGRPSPGTAAYGAAKAGLESLTRSLAVEWAPK-VRVNA
MMAR_5288|M.marinum_M GGASVVNMASMSALRAVTLVPGYGAAKAGIICVTRNLAVKWAAKGIRVNA
MUL_4361|M.ulcerans_Agy99 GGASVVNMASMSALRAVTLVPGYGAAKAGIICVTRNLAVKWAAKGIRVNA
MAV_4175|M.avium_104 GGASVVNVVSMSAFRSAVFVPGYASSKMGLVALTMNLSRRWAGDGIRVNA
Mflv_4818|M.gilvum_PYR-GCK DHAAVLNMVSVGAFIFAPMLSIYASMKAAMMSFTRSMAAEFVHDGIRVNA
Mvan_1624|M.vanbaalenii_PYR-1 EHAAVLNMVSVGAFIFAPMLSIYASMKAAMMSFTRSMAAEFVHHGIRVNA
MSMEG_1740|M.smegmatis_MC2_155 QNAAVLNMVSVGAFNFAPALSIYASSKAALMSVTRSMAAEFAPSGIRVNA
MLBr_01807|M.leprae_Br4923 -FGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANV
. : : *: . . *.: * .: .: .:: . : .*
Mb3579c|M.bovis_AF2122/97 VVVGMVETERSELFYGDAESIARVA-ATVPLGRLARPADIGWAAAFLASD
Rv3549c|M.tuberculosis_H37Rv VVVGMVETERSELFYGDAESIARVA-ATVPLGRLARPADIGWAAAFLASD
TH_2432|M.thermoresistible__bu VVVGMVETEQADLFYGDAESIAAIS-KNVPLGRLATPADVGWATAFLASD
MAB_0607|M.abscessus_ATCC_1997 LAAGMIRTELSEMHYGDEDGIAAVG-ATVPLGRLANPDEIGWTAAFLASP
MMAR_5288|M.marinum_M VAPGTIDTPMTAPMHLATELVDAEL-AHIPVRRFGSVGDIAPTVAFLCTE
MUL_4361|M.ulcerans_Agy99 VAPGTIDTPMTAPMHLATELVDAEL-AHIPVRRFGSVGDIAPTVAFLCTE
MAV_4175|M.avium_104 IAPGLIDTRMTHPAMGIPEVMDVEIGFHTPLGRPGTPADCAGATLFLCTE
Mflv_4818|M.gilvum_PYR-GCK LAPGPVDTDMMR--KNPQEAIDGMV-GGTLVGRLASADEMVGAALLLTSD
Mvan_1624|M.vanbaalenii_PYR-1 LAPGPVDTDMMR--KNPQEAIDGMV-GGTLLGRLATPDEMVGAALLLTSD
MSMEG_1740|M.smegmatis_MC2_155 LAPGPVDTDMMR--KNPQEAIDAMT-AGTLMKRLAHPDEMVGAALLLCSD
MLBr_01807|M.leprae_Br4923 VAPGFIDTEMTRAMDSKYQEAALQA---IPLGRIGAVEEIAGAVSFLASE
:. * : * : : * . : :. :* :
Mb3579c|M.bovis_AF2122/97 AASYISGATLEVHGGGEPPPYLGASSANK-------
Rv3549c|M.tuberculosis_H37Rv AASYISGATLEVHGGGEPPPYLGASSANK-------
TH_2432|M.thermoresistible__bu VASYISGASLEVHGGGEPPHYLAATNADAIK-----
MAB_0607|M.abscessus_ATCC_1997 LSSYVTGSVLTVHGGGERPAFLDAANVNSNENGEKE
MMAR_5288|M.marinum_M HSSYTNGAVFVVDGASDCV-----------------
MUL_4361|M.ulcerans_Agy99 HSSYTNGAVFVVDGASDCV-----------------
MAV_4175|M.avium_104 AASYITGSTIAVDGGYLTV-----------------
Mflv_4818|M.gilvum_PYR-GCK AGSYITGQVIIADGGGTPR-----------------
Mvan_1624|M.vanbaalenii_PYR-1 AGSYITGQVIIADGGGTPR-----------------
MSMEG_1740|M.smegmatis_MC2_155 AGSYMTGQVVIVDGGGTPR-----------------
MLBr_01807|M.leprae_Br4923 DAGYISGAVIPVDGGLGMGH----------------
..* .* . ..*.