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MTKSARAAARSAAADHAPPVPMWCAVGLSLAMIGSAAFNGVGVLCATVLVAVVIVALTRLHASAAGAATT SELLGSVLGPVSARFTGLVQLAAYAALGVGAAVSLGLQPLGMAGVDPETVLTSWLWPMWAGIGVIVAGTL VAVLPTRTVMAAVAVLAGLGLLAYFYLALAVIAKMASGSPQVMGGTESISTVDMLAAALPLGLSLFGFEA PTAASDRLRSVARPLGVAVGITAVCAVVLLVAVNLSTIAGFSHRATDLPLIVPELFGDMGRQSLNLASAL LGVAVVLATMWAATRVAARLFGGGVVTAVSVPAVMCVLTVVACRFPEDIGELLFVVPALLLFVVYVAVGE ANARVAGSPVAMQLPRAVLVVVLLAVLLISVREGYFILGSIWPLLVAAVITAAAAIFARTTPRPAHPPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5822 | - | - | 100% (419) | hypothetical protein MSMEG_5822 |
| M. smegmatis MC2 155 | MSMEG_0627 | - | 7e-05 | 23.82% (403) | glycosyl transferase, family protein 39 |
| M. smegmatis MC2 155 | MSMEG_0623 | snm | 9e-05 | 24.88% (414) | secretion protein Snm4 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2417 | - | 9e-06 | 20.68% (411) | hypothetical protein Mb2417 |
| M. gilvum PYR-GCK | Mflv_3578 | - | 4e-05 | 23.58% (352) | hypothetical protein Mflv_3578 |
| M. tuberculosis H37Rv | Rv2395 | - | 9e-06 | 20.68% (411) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4489 | - | 2e-06 | 26.18% (233) | hypothetical protein MMAR_4489 |
| M. avium 104 | MAV_4116 | - | 1e-43 | 33.73% (418) | hypothetical protein MAV_4116 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2787 | - | 1e-05 | 22.97% (296) | hypothetical protein MUL_2787 |
| M. vanbaalenii PYR-1 | Mvan_2919 | - | 4e-13 | 24.44% (450) | amino acid permease-associated region |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2417|M.bovis_AF2122/97 --------------------------------------------------
Rv2395|M.tuberculosis_H37Rv MSGATVGAREITIRGVVLGALITLVFTAANVYLGLRVGLTFATSIPAAVI
MSMEG_5822|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4116|M.avium_104 --------------------------------------------------
Mvan_2919|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3578|M.gilvum_PYR-GCK --------------------------------------------------
MUL_2787|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4489|M.marinum_M --------------------------------------------------
Mb2417|M.bovis_AF2122/97 --------------------------------------------------
Rv2395|M.tuberculosis_H37Rv SMGVLRLFANHSVVENNIVQTIASAAGTLSSIIFVLPALLMIGWWSGFPY
MSMEG_5822|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4116|M.avium_104 --------------------------------------------------
Mvan_2919|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3578|M.gilvum_PYR-GCK --------------------------------------------------
MUL_2787|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4489|M.marinum_M --------------------------------------------------
Mb2417|M.bovis_AF2122/97 --------------------------------------------------
Rv2395|M.tuberculosis_H37Rv WTTAAVCALGGILGVMYSIPLRRALVTGSDLPYPEGVAGAEVLKIGDSAR
MSMEG_5822|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4116|M.avium_104 --------------------------------------------------
Mvan_2919|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3578|M.gilvum_PYR-GCK -------------------MADMTEPHSAVIARLSADFAAISHQLTRVSG
MUL_2787|M.ulcerans_Agy99 --------------------------------MGHLDADKKTNHQPIEGD
MMAR_4489|M.marinum_M --------------------------------------------------
Mb2417|M.bovis_AF2122/97 -MEHNRRGIGVIALGAAAAAGYALLASLRVINNSLSATFRVGSGATMIGA
Rv2395|M.tuberculosis_H37Rv EMEHNRRGIGVIALGAAAAAGYALLASLRVINNSLSATFRVGSGATMIGA
MSMEG_5822|M.smegmatis_MC2_155 -MTKSAR-----AAARSAAADHAPPVPMWCA---------VGLSLAMIGS
MAV_4116|M.avium_104 -MPKRSL----LAQARPESGSGEYVLGTWRA---------AALSMAVIAP
Mvan_2919|M.vanbaalenii_PYR-1 -MNPEAS-----ETSEEIDQIPHRRLPFWVA---------LALSVALVGP
Mflv_3578|M.gilvum_PYR-GCK DLAALDRILTDRAPAAAAPRPAPQPAAYWPQYPPQPAPFRPWPQAPAPAP
MUL_2787|M.ulcerans_Agy99 CVSQGEATSVAVEGKGLKGGAVGLLSSVVIGTASTAPAYSLAATLGLIVA
MMAR_4489|M.marinum_M -MREGTFMRVGVVGVAAAAMVGGTVAVSPLT-----------MSGPMHAP
: .
Mb2417|M.bovis_AF2122/97 SLSLALIG------------VGHLVGVTVGVAMIVGLAIAFGVMLPIRTA
Rv2395|M.tuberculosis_H37Rv SLSLALIG------------VGHLVGVTVGVAMIVGLAIAFGVMLPIRTA
MSMEG_5822|M.smegmatis_MC2_155 ---AAFNG------------VGVLCATVLVAVVIVALTRLHASAAGAATT
MAV_4116|M.avium_104 ---AAWYG------------LGALLGAAVMIPVIYALARLRRHAPQARST
Mvan_2919|M.vanbaalenii_PYR-1 TLAMSGNGQGLIGTVGKSIPLVFLIGLVGVSLVGYSFVRLTRHLNHAGSA
Mflv_3578|M.gilvum_PYR-GCK TQALTPAPR----KERSEGWIGKLLAVAGVAVTLIGVVLLLVLAAQAGIL
MUL_2787|M.ulcerans_Agy99 SRGELLCG--------VKAPAIVLLSFIPMYMIAVAYQELNKAEPDCGTT
MMAR_4489|M.marinum_M NQGTCTAG--------------QQCDRLASVLIPKPPGEPAQPAGPAEIT
Mb2417|M.bovis_AF2122/97 GQLPPDGDYAVAVARIFST----DVRFIGAGAIAVAAAWTFLKILGPILR
Rv2395|M.tuberculosis_H37Rv GQLPPDGDYAVAVARIFST----DVRFIGAGAIAVAAAWTFLKILGPILR
MSMEG_5822|M.smegmatis_MC2_155 SELLG--------SVLGPV----SARFTGLVQLAAYAALGVGAAVSLGLQ
MAV_4116|M.avium_104 AELIG--------AMLGRK----AGTAAGIVQLLAYLVLAAQFAATLGLQ
Mvan_2919|M.vanbaalenii_PYR-1 YGLVG--------GTIGPR----TGFFSGFAMLGAYWGFSIGTLALTAAF
Mflv_3578|M.gilvum_PYR-GCK RPEFRVSAGGALAAALVGAGWWLNTRPGGRVGAIALVATGVAAAYMDVIA
MUL_2787|M.ulcerans_Agy99 FTWAS--------RAFGPV----TGWLGGWGIIAADVIVMANLAQIAGAY
MMAR_4489|M.marinum_M PAEAP--------QAMLPG-----LEQPPAVPAAARIPGGSGLPGGLDVG
: .
Mb2417|M.bovis_AF2122/97 G---IADAAVSARTRRRGQAVGQTERDIPIHIVAMVVLLSLIPIGWLLAD
Rv2395|M.tuberculosis_H37Rv G---IADAAVSARTRRRGQAVGQTERDIPIHIVAMVVLLSLIPIGWLLAD
MSMEG_5822|M.smegmatis_MC2_155 P---LGMAGVDPET---------------------------VLTSWLWPM
MAV_4116|M.avium_104 L---LQLLSPGDDP--------------------------AAIVSWLPVG
Mvan_2919|M.vanbaalenii_PYR-1 VNSFIAALQPGDETP--------------------------YQAPWLLIV
Mflv_3578|M.gilvum_PYR-GCK VTTIYDWVPAPAGLVLAAVIAGAGLTLARRWDSEHLGLLVLVPLIVLAPI
MUL_2787|M.ulcerans_Agy99 SFTFVGELGWQSASN--------------------------LAHSTLWST
MMAR_4489|M.marinum_M GSALTALPPPAGVP----------------------------DVGIPGVG
Mb2417|M.bovis_AF2122/97 FTDGTPLDDRRPGAIAAGVLLVLVIGLMVAAVCGYMAGLIGSSNSPISGV
Rv2395|M.tuberculosis_H37Rv FTDGTPLDDRRPGAIAAGVLLVLVIGLMVAAVCGYMAGLIGSSNSPISGV
MSMEG_5822|M.smegmatis_MC2_155 WAG--------IGVIVAGTLVAVLPTRTVMAAVAVLAGLG--------LL
MAV_4116|M.avium_104 AAA---------AALVVGATACWASTRAVASLAMPLVLAG--------LL
Mvan_2919|M.vanbaalenii_PYR-1 VIG-----------AVISFLLSGRDIQLLAKILLAIEGIG--------IL
Mflv_3578|M.gilvum_PYR-GCK VTDG-------VSLLLVGFMLALAAVSLPVQLGKDWIWLHAARIAAAVLP
MUL_2787|M.ulcerans_Agy99 VAG--------VAWIVVMTCICYRGTDVSARMQYVLLSVE--------LV
MMAR_4489|M.marinum_M IPG--------VGLPSVGVPTVGFPTIGVPSVPNVVGSVLG---------
Mb2417|M.bovis_AF2122/97 GILVVVLAGLLIKTAYGPATGSQIPALVAYTVFTAALVFGVATISNDNLQ
Rv2395|M.tuberculosis_H37Rv GILVVVLAGLLIKTAYGPATGSQIPALVAYTVFTAALVFGVATISNDNLQ
MSMEG_5822|M.smegmatis_MC2_155 AYFYLALAVIAKMASGSPQVMGGTESISTVDMLAAALPLGLSLFG-----
MAV_4116|M.avium_104 LYVCLAVAVTALVTLSTDPVVIGS-AATPRPLSGQLVGFGLGMVG-----
Mvan_2919|M.vanbaalenii_PYR-1 AMIVLVVAIFAQGGAPGTGIDFSVFSFSDGDVSGSAVLAGVVAAFLSWAG
Mflv_3578|M.gilvum_PYR-GCK LLVALAARHIDSREDLWLAGACGIAAVIALTAALILLPGTGNRVVMALLT
MUL_2787|M.ulcerans_Agy99 VLVALAAVALARVYTNHGDVGSLRPSLSWLWPSGLDFGTQMAPALLITIF
MMAR_4489|M.marinum_M ----ITGSVTSAVTSGALAVTYVMLAYNTLRSAGILPDLSVPISSVTN--
:. :
Mb2417|M.bovis_AF2122/97 DLK-TGQLVGATPWKQQVALIIGVLVGSVVMAPILQLMQAGFG--FQGAP
Rv2395|M.tuberculosis_H37Rv DLK-TGQLVGATPWKQQVALIIGVLVGSVVMAPILQLMQAGFG--FQGAP
MSMEG_5822|M.smegmatis_MC2_155 ----FEAPTAASDRLRSVARPLGVAVGITAVCAVVLLVAVNLS--TIAGF
MAV_4116|M.avium_104 ----VELLTVRTPRIARPGRSMSLATAVVAAAAVVLWVGDHRG--VAGPW
Mvan_2919|M.vanbaalenii_PYR-1 ----FEACASMGEETDDPKRNIPRALGGTLILTGVLFVVVMFA--QVVGF
Mflv_3578|M.gilvum_PYR-GCK VAG-IVPVLCVNLAVDRVVAALMAAALAAALLAVALLADRLPG--VDGVV
MUL_2787|M.ulcerans_Agy99 IYWGFDTAVACNDETDDPGRTLGRAAVISTFLLLATYAVVTVASIAFAGV
MMAR_4489|M.marinum_M ----MLLPSTATASSLLPTLAAPGLAALPGLTPAGLVTLASMG----GIP
.
Mb2417|M.bovis_AF2122/97 GATANALAAPQA--ALMSALAKGVFGGSLNWSLVGVGALTGV------IA
Rv2395|M.tuberculosis_H37Rv GATANALAAPQA--ALMSALAKGVFGGSLNWSLVGVGALTGV------IA
MSMEG_5822|M.smegmatis_MC2_155 SHRATDLPLIVP--ELFGDMGRQSLN--LASALLGV-------------A
MAV_4116|M.avium_104 RWSATMLAEAVP--EFYTDEGRRWMA--AAGIALAV-------------A
Mvan_2919|M.vanbaalenii_PYR-1 GTDAAGLEAFQSSGNTLGDLGGTYIGQWFSLVIIFTAIVSAFGCHLATSA
Mflv_3578|M.gilvum_PYR-GCK RRVFAVTSAIAALIAVTTAFDGRVGGPVLLAMAVVVAIAVGRDVVGRWVA
MUL_2787|M.ulcerans_Agy99 GVDGIGLGNPDNSNDVFAAVGPALFGDGVLGKIGLLLLSASILTSASAST
MMAR_4489|M.marinum_M GLSLPALSGVSP-ATLLTEAANALPGLASVSTTDLL--------------
Mb2417|M.bovis_AF2122/97 VALDETLAKTTTNLRLPPLAVGMG----------MYLPAALTLMIPIGAF
Rv2395|M.tuberculosis_H37Rv VALDETLAKTTTNLRLPPLAVGMG----------MYLSAALTLMIPIGAF
MSMEG_5822|M.smegmatis_MC2_155 VVLATMWAATRVAARLFGGGVVTA----------VSVPAVMCVLTVVACR
MAV_4116|M.avium_104 AALVTGWAATRAAAGLAAMRGATPNAG----LRLTVMGLVAVVAVVVSAH
Mvan_2919|M.vanbaalenii_PYR-1 TSGRMLYAFGRDGFGPKALAHIHAETGGPRRATWLVVVVALLVDLICGAT
Mflv_3578|M.gilvum_PYR-GCK IGFAVIGAAAHLSYAPLAVLLQPVEVSTATGISTLVSSLLLATAAVTIVW
MUL_2787|M.ulcerans_Agy99 QTTILPTARTTLSMAVYKALPASFAKIHPRYLTPTVSTIAMGAVSILFYV
MMAR_4489|M.marinum_M -AVAVMGGAPQLASMLPMLQAALPG---------MSATDVMAMVTGGLPQ
.
Mb2417|M.bovis_AF2122/97 LGRIYDS---------WARWSGDDDERKKRLGVMLATGLIVGES------
Rv2395|M.tuberculosis_H37Rv LGRIYDS---------WARWSGDDDERKKRLGVMLATGLIVGES------
MSMEG_5822|M.smegmatis_MC2_155 FPEDIGE---------LLFVVPALLLFVVYVAVGEANARVAGSP------
MAV_4116|M.avium_104 GMRSIGM---------VILGAAPLLLMALYVLVAEANSRIPGDS------
Mvan_2919|M.vanbaalenii_PYR-1 GWPDMGTGNAAINTYFLFAVAGSVCLMVCYLLVEIAAAYFVGAPKFESVH
Mflv_3578|M.gilvum_PYR-GCK MWDRTETALWVGAAVVTVYAVTSCTVTAGMLVIGGDGGFYAGHMVATILW
MUL_2787|M.ulcerans_Agy99 LFTLVSRN-----LLSALIGSVGLVIAFYYGLTGYACAHYYRATLTKSLR
MMAR_4489|M.marinum_M LPGGLPN-------LQAILPGGDPTMLAAALPALAAGGLPALPAAG----
.
Mb2417|M.bovis_AF2122/97 -----LYGVLFAVIVATTGKEEP------------------LAMVGDGFR
Rv2395|M.tuberculosis_H37Rv -----LYGVLFAVIVATTGKEEP------------------LAMVGDGFR
MSMEG_5822|M.smegmatis_MC2_155 -----VAMQLPRAVLVVVLLAVL------------------LISVREGYF
MAV_4116|M.avium_104 -----VVAWWVRLVMPALAVVAV------------------VKPLVDSQF
Mvan_2919|M.vanbaalenii_PYR-1 GGTGRVAGLVLPLLGAVVIVTVL------------------WFNVKDADS
Mflv_3578|M.gilvum_PYR-GCK IAMAAVLFWYAARLPREDRSVPLGG-----------GLGLVAAAMAKLFL
MUL_2787|M.ulcerans_Agy99 N---FVMRGVVPLTGGVVLTVVFIFGLIEYAKRDWLVENGHNVTIFGFGA
MMAR_4489|M.marinum_M --LPALPAAGLPALPAAGLPALPAG----------------LPAPKVGLP
:
Mb2417|M.bovis_AF2122/97 FASQPLGAIVFAGLLAWLYQRTRVTASYRLAAPAGSSKPLPDLPG-----
Rv2395|M.tuberculosis_H37Rv FASQPLGAIVFAGLLAWLYQRTRVTASYRLAAPAGSSKPLPDLPG-----
MSMEG_5822|M.smegmatis_MC2_155 ILGS-----IWPLLVAAVITAAAAIFARTTPRPAHPPR------------
MAV_4116|M.avium_104 APVQVAT--VVAAAIGVGAAGAAPLLARHRERTAKSE-------------
Mvan_2919|M.vanbaalenii_PYR-1 WSAAPMLGLYWCALGLVIAVALSGIAKRVGESLAIELELVPRPTGAVEPT
Mflv_3578|M.gilvum_PYR-GCK FDLGTLDGIFRVVVFIVVGLTLLGIGAGYARLLERQDKQAATRTFDTT--
MUL_2787|M.ulcerans_Agy99 VAVVGVGSMLLGVVVMLIWWAISPGFFRGRTLRRHSADLLLEPAVSPPAH
MMAR_4489|M.marinum_M SLGGPPAPPQLPQLPALPAPAPPKISPPKISPPRLCTPTIGPIGSTCTPN
Mb2417|M.bovis_AF2122/97 -------------------------------------------
Rv2395|M.tuberculosis_H37Rv -------------------------------------------
MSMEG_5822|M.smegmatis_MC2_155 -------------------------------------------
MAV_4116|M.avium_104 -------------------------------------------
Mvan_2919|M.vanbaalenii_PYR-1 QPA----------------------------------------
Mflv_3578|M.gilvum_PYR-GCK -------------------------------------------
MUL_2787|M.ulcerans_Agy99 LALPDSGDMQTVIAADLSNLPAGETAVNPQTGQHLTKDTSGAS
MMAR_4489|M.marinum_M -------------------------------------------