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VYVFAEEFCEGPVTSGAVMPIVRVAILADSRLIEMALPTELPLREILPAVKRLVVPAASDNDSPLAANAS LHLSLAPIGGAPFSLDASLDTVGVVDGDLLALQPVPVGPAAPGIVEDIADAAMIFSTARLQSWGPTHIRR GALAATTAVTFAATGLGVTYRAVTGALTGLLVVIVIAVLIALGGLVLRSRAARTGLVLSIAALVPIGAVF ALAVPGIFGPAQVLLASAGVTAWSLIALIVPGPERVRIVAFFTATVVIGVAVMLEAGAALLWQLTPLTIG CGLILAALLVTVEAAQLSALWARFPLPVIPAPGDPTPSAPSFQVLEDLPRRVRISSAHQSGFIAAATLLS MLGSVAIALRPEAVSSVGWYLVAATAVAATLRARVWDSVACKAWLLAQPYLVASVLLGLYTATGRYVAAS AALLVLVVVVLAWAVVALNPRIASSDSYSLPLRRLLGMVASGLDASLIPAMAYLVSLFSWVLNR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_02529 | - | - | 100% (485) | hypothetical protein MLBr_02529 |
| M. leprae Br4923 | MLBr_00047 | - | 2e-22 | 25.77% (520) | hypothetical protein MLBr_00047 |
| M. leprae Br4923 | MLBr_01539 | - | 5e-14 | 25.24% (416) | hypothetical protein MLBr_01539 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0298 | - | 0.0 | 76.22% (471) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_0321 | - | 1e-136 | 55.88% (485) | hypothetical protein Mflv_0321 |
| M. tuberculosis H37Rv | Rv0290 | - | 0.0 | 76.43% (471) | transmembrane protein |
| M. abscessus ATCC 19977 | MAB_2226c | - | 1e-141 | 55.93% (472) | hypothetical protein MAB_2226c |
| M. marinum M | MMAR_0549 | - | 0.0 | 74.10% (471) | transmembrane protein |
| M. avium 104 | MAV_4863 | - | 0.0 | 72.71% (480) | hypothetical protein MAV_4863 |
| M. smegmatis MC2 155 | MSMEG_0623 | snm | 1e-148 | 59.62% (478) | secretion protein Snm4 |
| M. thermoresistible (build 8) | TH_3948 | - | 1e-148 | 59.24% (476) | PUTATIVE secretion protein Snm4 |
| M. ulcerans Agy99 | MUL_1212 | - | 0.0 | 73.46% (471) | transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_0420 | - | 1e-141 | 55.88% (485) | hypothetical protein Mvan_0420 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0321|M.gilvum_PYR-GCK ------MPQSALSDTN-TAMPIVRVAVLTATAGDEDG-DRAGRLTEIALP
Mvan_0420|M.vanbaalenii_PYR-1 ------MPPLDTNTLAGVVMPIVRVAVLTAAVGDEAAADRTGRITEIALP
MSMEG_0623|M.smegmatis_MC2_155 ------MSEN-------TVMPIVRVAVLAAG-------DDGGRLTEMALP
TH_3948|M.thermoresistible__bu ------MSDN-------TVMPIVRVAVLAAG-------DDGGRLTEMALP
Mb0298|M.bovis_AF2122/97 --------------MSGTVMQIVRVAILADS-----------RLTEMALP
Rv0290|M.tuberculosis_H37Rv --------------MSGTVMQIVRVAILADS-----------RLTEMALP
MMAR_0549|M.marinum_M --------------MSGTVMPIVRVAILADS-----------RLTEVALP
MUL_1212|M.ulcerans_Agy99 --------------MSGTVMPIVRVAILADS-----------RLTEVALP
MAV_4863|M.avium_104 -------------MTSGTVMPIVRVAILADS-----------RLTEMALP
MLBr_02529|M.leprae_Br4923 MVYVFAEEFCEGPVTSGAVMPIVRVAILADS-----------RLIEMALP
MAB_2226c|M.abscessus_ATCC_199 -------------MSDNAVMPIVRVAVLGEE-----------KLTEVALP
..* *****:* :: *:***
Mflv_0321|M.gilvum_PYR-GCK AQLPLREIIPAVQRIVAPSDDAPG---------------TDPVSLAPIGG
Mvan_0420|M.vanbaalenii_PYR-1 ADLPLREIVPAVQRIVAPSDDSAGG--------------AEQLSLAPIGG
MSMEG_0623|M.smegmatis_MC2_155 SELPLREILPAVQRIVQPARENDGAA------DPAAAPNPVRLSLAPIGG
TH_3948|M.thermoresistible__bu AELPLREILPAVQQMAAPTEDG------------ADVPDAVRLSLAPIGG
Mb0298|M.bovis_AF2122/97 AELPLREILPAVQRLVVPSAQNGDG-------GQADSGAAVQLSLAPVGG
Rv0290|M.tuberculosis_H37Rv AELPLREILPAVQRLVVPSAQNGDG-------GQADSGAAVQLSLAPVGG
MMAR_0549|M.marinum_M AELPLREILPAVQRLVIPVAEDGDA-------GSADLGIAGHLSLAPVGG
MUL_1212|M.ulcerans_Agy99 AELPLREILPAVQRLVIPVAEDGDA-------GSADLGIAGHLSLAPVGG
MAV_4863|M.avium_104 AELPLREILPAVQRLVVPAAANGDSEDGAPSRGAAEVGGAVQLSLAPIGG
MLBr_02529|M.leprae_Br4923 TELPLREILPAVKRLVVPAASDNDS--------PLAANASLHLSLAPIGG
MAB_2226c|M.abscessus_ATCC_199 TQLPMRDIIPAVHRMVAPDATEATT--------------PQRLSLAPVNG
::**:*:*:***:::. * . :****:.*
Mflv_0321|M.gilvum_PYR-GCK APYSLDATLTTVGVVDGDLLALQPIPAGPPAPRIVEDIADAAMIFSAARE
Mvan_0420|M.vanbaalenii_PYR-1 APFSLDATLNTVGVVDGDLLALQPVPAGPPAPRIVEDIADAAMIFSASRE
MSMEG_0623|M.smegmatis_MC2_155 APFSLDATLDTVGVVDGDLLALQAVPSGPPAPRIVEDIADAAVIFSEARR
TH_3948|M.thermoresistible__bu APFSLDATLQTVGVVDGDLLALQPIPSGPPAPRIVEDIADAAVIFSAART
Mb0298|M.bovis_AF2122/97 QPFSLDASLDTVGVVDGDLLVLQPVPAGPAAPGIVEDIADAAMIFSTSRL
Rv0290|M.tuberculosis_H37Rv QPFSLDASLDTVGVVDGDLLVLQPVPAGPAAPGIVEDIADAAMIFSTSRL
MMAR_0549|M.marinum_M APFSLDASLDTVGVVDGDLLVLQPVPTGPAAPGIVEDIADAAMIFSTSRL
MUL_1212|M.ulcerans_Agy99 APFSLDASLDTVGVVDGDLLVLQPVPTGPAAPGIVEDIADAAMIFSTSRL
MAV_4863|M.avium_104 APFSLDASLDTVGVVDGDLLALQPVPAGPAAPGIVEDIADAAMIFSTSRL
MLBr_02529|M.leprae_Br4923 APFSLDASLDTVGVVDGDLLALQPVPVGPAAPGIVEDIADAAMIFSTARL
MAB_2226c|M.abscessus_ATCC_199 APFSADATLDTVGVVDGDLLTLRPTPAGPAAPGIVEDIADAAVIFSESRK
*:* **:* **********.*:. * **.** *********:*** :*
Mflv_0321|M.gilvum_PYR-GCK KPWGTPQIQRGATVAVVGLMLVATALAVAHRVVTDSIIGVFAVSAVAIAA
Mvan_0420|M.vanbaalenii_PYR-1 KPWGVANIRSGATAAVIGLTVVATALAVAHRVFTDSLIGLFAVSAVAIGA
MSMEG_0623|M.smegmatis_MC2_155 RQWGPTHIARGAALALIGLILVGTGLSVAHRVITGDLLGQFIVSGIALAT
TH_3948|M.thermoresistible__bu RPWSPAHIARAAAVALIGLILAASALSVAHRILTGDVLGLFVVSGVAVAT
Mb0298|M.bovis_AF2122/97 KPWGIAHIQRGALAAVIAVALLATGLTVTYRVATGVLAGLLAVAGIAVAS
Rv0290|M.tuberculosis_H37Rv KPWGIAHIQRGALAAVIAVALLATGLTVTYRVATGVLAGLLAVAGIAVAS
MMAR_0549|M.marinum_M RPWDARHLQRGALAALIGVALAGSGLAVAYRAATGALAGLLIVSVIAVAM
MUL_1212|M.ulcerans_Agy99 RPWDARHLQRGALAALIGVALAGSGLAVAYRVATGALAGLLIVSVIAVAM
MAV_4863|M.avium_104 RPWGTTHIQRFALATVIAVALLATGLSVSYRVATGALAGLVAVSAVAALT
MLBr_02529|M.leprae_Br4923 QSWGPTHIRRGALAATTAVTFAATGLGVTYRAVTGALTGLLVVIVIAVLI
MAB_2226c|M.abscessus_ATCC_199 RPWGAEHIARVGRFGVLGLIAAATILAIVHSIRTGSSLSLAGLAVVAVAA
: *. :: . .: .: * : : *. . : :*
Mflv_0321|M.gilvum_PYR-GCK VLGALVARTGSPRVATALAAAALPSVGAAFTLAVPGDFGASAVLLGAAGI
Mvan_0420|M.vanbaalenii_PYR-1 VLGALLARASSPRLATALAAAALPSVAAAFTLAVPGDFGASNIVLGAAGV
MSMEG_0623|M.smegmatis_MC2_155 VIAALAVRNRSAVLATSLAVTALVPVAAAFALGVPGDFGAPNVLLAAAGV
TH_3948|M.thermoresistible__bu VLAALLARPRSIPLAAALSVAALVPVGAAFALAVPGDFGAPHLLLAAAGV
Mb0298|M.bovis_AF2122/97 ALAGLLITIRSPRSGIALSIAALVPIGAALALAVPGKFGPAQVLLGAAGV
Rv0290|M.tuberculosis_H37Rv ALAGLLITIRSPRSGIALSIAALVPIGAALALAVPGKFGPAQVLLGAAGV
MMAR_0549|M.marinum_M ALAGLLLGARSPRTGIALSIAALAPVGAALALAVPGSFGAAQVLLAAAGV
MUL_1212|M.ulcerans_Agy99 ALAGLLLGARSPRTGIALSIAALAPVGAALALAVPGSFGAAQVLLAAAGV
MAV_4863|M.avium_104 AIVGLLATARSPRNGMALSIAALVPIGAALALAVPGRFGPAQVMLAAAGV
MLBr_02529|M.leprae_Br4923 ALGGLVLRSRAARTGLVLSIAALVPIGAVFALAVPGIFGPAQVLLASAGV
MAB_2226c|M.abscessus_ATCC_199 AIGALVAHVRSARLGAELAVAALVPIAGALALAVPGSGLAPRVLLGAAGV
.: .* : . *: :** .:...::*.*** .. ::*.:**:
Mflv_0321|M.gilvum_PYR-GCK AAWSIISIT--VGERA--IAVFTAVAAAALGVAVAAAAATVWSLSLLDIG
Mvan_0420|M.vanbaalenii_PYR-1 AAWSVISIT--VGERA--IALFTAAAASALGVLLVSAVASVWTLTPVHVG
MSMEG_0623|M.smegmatis_MC2_155 AAWSLISMAGSPDDRG--IAVFTATAVTGVGVLLVAGAASLWVISSDVIG
TH_3948|M.thermoresistible__bu TAWSIISIT--VAERS--VAVFTTASVLGVATMAAAAAATLWEPSWVVLG
Mb0298|M.bovis_AF2122/97 AAWSLIALMIPSAERERVVAFFTAAAVVGASVALAAGAQLLWQLPLLSIG
Rv0290|M.tuberculosis_H37Rv AAWSLIALMIPSAERERVVAFFTAAAVVGASVALAAGAQLLWQLPLLSIG
MMAR_0549|M.marinum_M TAWSLICLMVPGEQRERIVALFTAVAVVGAALLLAAGAELLWQLPVSSIG
MUL_1212|M.ulcerans_Agy99 TAWSLICLMVPGEQRERIVALFTAVAVVGAALLLAAGVELLWQLPVSSIG
MAV_4863|M.avium_104 TAWSLIALMAPSAERERLAGFFTATAVLGAAVLLAAGAELLWHITPVALG
MLBr_02529|M.leprae_Br4923 TAWSLIALIVPGPERVRIVAFFTATVVIGVAVMLEAGAALLWQLTPLTIG
MAB_2226c|M.abscessus_ATCC_199 AAWSLIYLIV----ARQLIAFFTATTVLSLGIAGAAGAHVLWHPSLLVVG
:***:* : ..**:. . . . :.. :* . :*
Mflv_0321|M.gilvum_PYR-GCK CVLILIALLITVQAAQLSAMCARLPVPVIPAPGDPAPSALPRRVLEDLPR
Mvan_0420|M.vanbaalenii_PYR-1 CILILAGLVVTVQAAQLSAMCARLPVPVIPAPGDPTPSAPPLRVLEDLPR
MSMEG_0623|M.smegmatis_MC2_155 CALVLLGLIVTVQAAQLSAMWARFPLPVIPAPGDPTPAARPLSVLADLPR
TH_3948|M.thermoresistible__bu CGLIVLGLLVTVQAAQLSAMFARFPLPVIPAPGDPTPSAQPLRVLEDLPR
Mb0298|M.bovis_AF2122/97 CGLIVAALLVTIQAAQLSALWARFPLPVIPAPGDPTPSAPPLRLLEDLPR
Rv0290|M.tuberculosis_H37Rv CGLIVAALLVTIQAAQLSALWARFPLPVIPAPGDPTPSAPPLRLLEDLPR
MMAR_0549|M.marinum_M CGLIVAALLVTIQAAQLSAVWARFPLPVIPAPGDPTPSAPSLRVLEDLPR
MUL_1212|M.ulcerans_Agy99 CGLIVAALLVTIQAAQLSAVWARFPLPVIPAPGDPTPSAPSLRVLEDLPR
MAV_4863|M.avium_104 CGLIVAALLVTVEAAPLSALWARFPLPVIPAPGDPTPSAPPLPVLEDLPR
MLBr_02529|M.leprae_Br4923 CGLILAALLVTVEAAQLSALWARFPLPVIPAPGDPTPSAPSFQVLEDLPR
MAB_2226c|M.abscessus_ATCC_199 CGLIIVALLVTVRAAQLSAFAARFPLPTIPAPGDATPSAPAMSVLKDLPR
* *:: .*::*:.** ***. **:*:*.******.:*:* . :* ****
Mflv_0321|M.gilvum_PYR-GCK RIRAGDAYQTGFIAAGVLLAVTGSVLVVWPAVSGDGGVPVWSWYLVAATA
Mvan_0420|M.vanbaalenii_PYR-1 RIRASDAHQTGFIAAGVLLGVAGSVFAVWPGVGGDGSASPWAWLLVGATA
MSMEG_0623|M.smegmatis_MC2_155 RVRVSQAHQTGVIAAGVLLGVAGSVALVSSAN-----ASPWAWYIVVAAA
TH_3948|M.thermoresistible__bu RVRVGDSHQTGLIAAGVLLSVAGSVALVAPPG-----ASGWAWYVVVAAA
Mb0298|M.bovis_AF2122/97 RVRVSDAHQSGFIAAAVLLSVLGSVAIAVRPEA----LSVVGWYLVAATA
Rv0290|M.tuberculosis_H37Rv RVRVSDAHQSGFIAAAVLLSVLGSVAIAVRPEA----LSVVGWYLVAATA
MMAR_0549|M.marinum_M RVRVSDAHQSGFIAAAVLLSVLGSVAIALRPDT----VSALGWYVVAATA
MUL_1212|M.ulcerans_Agy99 RVRVSDAHQSGFIAAAVLLSVLGSVAIALRPDT----VSALGWYVVAATA
MAV_4863|M.avium_104 RVRIGDAHQSGFIAAAVLLSALGSVAIALRPET----LSAAGWYVVGATA
MLBr_02529|M.leprae_Br4923 RVRISSAHQSGFIAAATLLSMLGSVAIALRPEA----VSSVGWYLVAATA
MAB_2226c|M.abscessus_ATCC_199 RVQLSDSHQSGFIAGASILAILGSLAVVGGAAP----ASPWAWYLVAAVS
*:: ..::*:*.**.. :*. **: . . .* :* *.:
Mflv_0321|M.gilvum_PYR-GCK LAAALRARVWDSSACKAWLLGHGYLVTTVLLVLSAAHEKYSAAWWALGVL
Mvan_0420|M.vanbaalenii_PYR-1 LGAVLRARVWDSASCKAWLLAQPFLMSAVLLGIFAVTGRYDAAWWTLGAF
MSMEG_0623|M.smegmatis_MC2_155 AGAALRARVWDSAACKAWLLGHSYLLAVALLVAFVIGDRYQAALWALAAL
TH_3948|M.thermoresistible__bu AGSTLRARVWDAASCKLWLLSHSYLITVALLIGFTVTERYPAAWLALAVL
Mb0298|M.bovis_AF2122/97 AAATLRARVWDSAACKAWLLAQPYLVAGVLLVFYTTTGRYVAAFGAVLVL
Rv0290|M.tuberculosis_H37Rv AAATLRARVWDSAACKAWLLAQPYLVAGVLLVFYTATGRYVAAFGAVLVL
MMAR_0549|M.marinum_M ATATLRARIWDSAACKAWLLTQPYLVGGTLLVLYAATGHFIAAFGALVVL
MUL_1212|M.ulcerans_Agy99 ATATLRARIWDSAACKAWLLTQPYLVGGTLLVLYAATGHFIAAFGALVVL
MAV_4863|M.avium_104 ATSVLRARVWDSAACKAWLLAQPYLAAGVLLVLYTATGRYAGALGAVLVL
MLBr_02529|M.leprae_Br4923 VAATLRARVWDSVACKAWLLAQPYLVASVLLGLYTATGRYVAASAALLVL
MAB_2226c|M.abscessus_ATCC_199 AGAALRARVWDSAVCKAWLLAVPFLVSTALLVIFAVEDRYTGALVALGVL
:.****:**: ** *** :* .** . :: .* :: .:
Mflv_0321|M.gilvum_PYR-GCK AVLVAAWAVAALNPRIAQPDTYSLPMRRVVGFVATALDASVIPVMAYLVG
Mvan_0420|M.vanbaalenii_PYR-1 AVLAAAWVVAALNPRIAEPQTYSLPMRRLLGFVAAAVDASVIPVMAYLVG
MSMEG_0623|M.smegmatis_MC2_155 AVLVLVWIVAALNPKIASPDTYSLPMRRMVGFLATGLDASLIPVMALLVG
TH_3948|M.thermoresistible__bu ALLVTVWAVVVAYPRIASPDSYSLPMRRLTGFLATALDASLIPVMAYLVG
Mb0298|M.bovis_AF2122/97 AVLMLAWVVVALNPGIASPESYSLPLRRLLGLVAAGLDVSLIPVMAYLVG
Rv0290|M.tuberculosis_H37Rv AVLMLAWVVVALNPGIASPESYSLPLRRLLGLVAAGLDVSLIPVMAYLVG
MMAR_0549|M.marinum_M AVLAVAWVVVALNPVIASPESYSLPLRRLLGFLAAGLDASLIPVMAYLVG
MUL_1212|M.ulcerans_Agy99 AVLAVAWVVVALNPVIASPESYSLPLRRLLGFLAAGLDASLIPVMAYLAG
MAV_4863|M.avium_104 LALVAVWIVVALNPGIAAPESYSLPVRRLVGFVATGLDASLIPVMAFVVG
MLBr_02529|M.leprae_Br4923 VVVVLAWAVVALNPRIASSDSYSLPLRRLLGMVASGLDASLIPAMAYLVS
MAB_2226c|M.abscessus_ATCC_199 ALLVAAVAVVVFNPKIGEAESYSLPSRRLLGFLASGIDASLLPVIAYLTG
: . *.. * *. .::**** **: *::*:.:*.*::*.:* :..
Mflv_0321|M.gilvum_PYR-GCK LFTLVLNGF
Mvan_0420|M.vanbaalenii_PYR-1 LFAWALNGV
MSMEG_0623|M.smegmatis_MC2_155 LFSLVLDR-
TH_3948|M.thermoresistible__bu LFSWVLNR-
Mb0298|M.bovis_AF2122/97 LFAWVLNR-
Rv0290|M.tuberculosis_H37Rv LFAWVLNR-
MMAR_0549|M.marinum_M LFTWVLNR-
MUL_1212|M.ulcerans_Agy99 LFTWVLNR-
MAV_4863|M.avium_104 LFGWVLDR-
MLBr_02529|M.leprae_Br4923 LFSWVLNR-
MAB_2226c|M.abscessus_ATCC_199 LFSWILNR-
** *: