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MAVDPAAGESALIERISELETLKCAAAAAQARAAAALDAARRAAEAAAGVPAARRGRGVASEVALARRDS PARGGRHLGFAKALVHEMPHTLAALECGALSEWRATLIVRESACLDAEDRRALDAELCADPAGLSGMGDA RVAAAAKAIAYRLDPHAVVERAAKAENDRTVTIRPAPDTMTYLTALLPVAQGVSVYAALRREADTRGDGR PRGQVMADTLVERVTGRRSTVPTPVAVNLVLSDETLLGGADAPGEISGYGPIPAAVARRMVANAAADPRS RATLRRLYAHPRAGALVAMESRARLFPQGLARFIGLRDQRCRTPYCDAPIRHRDHAQPWADGGATSAGNG LGLCEHCNYVKETSGWTVSAGVDETHTHTALFTTPTGQTYRSTAPPRAPAITMSTVEVRVAVAFARHAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3980 | - | - | 100% (419) | hypothetical protein MAV_3980 |
| M. avium 104 | MAV_0536 | - | 3e-23 | 27.95% (440) | hypothetical protein MAV_0536 |
| M. avium 104 | MAV_3457 | - | 8e-22 | 28.33% (406) | 13e12 repeat-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3101 | - | 0.0 | 80.38% (418) | hypothetical protein Mb3101 |
| M. gilvum PYR-GCK | Mflv_2586 | - | 1e-134 | 62.60% (393) | hypothetical protein Mflv_2586 |
| M. tuberculosis H37Rv | Rv3074 | - | 0.0 | 80.38% (418) | hypothetical protein Rv3074 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1907 | - | 1e-137 | 62.72% (397) | hypothetical protein MAB_1907 |
| M. marinum M | MMAR_1584 | - | 0.0 | 81.10% (418) | hypothetical protein MMAR_1584 |
| M. smegmatis MC2 155 | MSMEG_6025 | - | 1e-144 | 63.68% (413) | hypothetical protein MSMEG_6025 |
| M. thermoresistible (build 8) | TH_0334 | - | 2e-17 | 26.34% (372) | HNH endonuclease |
| M. ulcerans Agy99 | MUL_2679 | - | 2e-22 | 25.62% (406) | 13e12 repeat-containing protein |
| M. vanbaalenii PYR-1 | Mvan_4725 | - | 1e-136 | 61.17% (412) | hypothetical protein Mvan_4725 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3101|M.bovis_AF2122/97 ----------MFETLTAIDPDAEEAALIERIAELERLKSAAAAGQARAAA
Rv3074|M.tuberculosis_H37Rv ----------MFETLTAIDPDAEEAALIERIAELERLKSAAAAGQARAAA
MMAR_1584|M.marinum_M ----------MFESLAAVDPAADQAALVERIAELETVKSAAAAGQARAAA
MAV_3980|M.avium_104 ---------------MAVDPAAGESALIERISELETLKCAAAAAQARAAA
Mflv_2586|M.gilvum_PYR-GCK ----------MFESLFDIDEGASQAELRAVVERCERLKSAAAAAQARATA
Mvan_4725|M.vanbaalenii_PYR-1 ----------MFESMFDVDETASQAELRAAVERLERLKSQAAAAQARATA
MSMEG_6025|M.smegmatis_MC2_155 MSVRGCSVWHMFESLFDIDPQASEAELRDRIEQFERMKSAAAAAQATASV
MAB_1907|M.abscessus_ATCC_1997 --------------MLPLDPATRAAQLVDRIAELERVKAAAAAEQAHAAV
TH_0334|M.thermoresistible__bu -----------------MFESLDDGAVVDSIAAASREQSAACGREMLAIG
MUL_2679|M.ulcerans_Agy99 ----------MDQHIIEYVFDTDDSAPLTRITAAARAEARAAAERLAAIG
. : :. *.. . *
Mb3101|M.bovis_AF2122/97 AVDAARRAAEGAAGVPAARRGRG-LASEIALARRDSPARGSRHLGFAKAL
Rv3074|M.tuberculosis_H37Rv AVDAARRAAEGAAGVPAARRGRG-LASEIALARRDSPARGSRHLGFAKAL
MMAR_1584|M.marinum_M ALDTARRAAESAAGVPAARRGRG-LANEIALARRDSPARGSRHLGFAKAL
MAV_3980|M.avium_104 ALDAARRAAEAAAGVPAARRGRG-VASEVALARRDSPARGGRHLGFAKAL
Mflv_2586|M.gilvum_PYR-GCK LWAAKRAAAEEAAGVPVRRRGKG-LASEVALARRDAPVKGGQHLGFAKAL
Mvan_4725|M.vanbaalenii_PYR-1 LWAAKRQLAEESAGVRAHHRGKG-LASEVALARRDAPVKGNQHLGFAKAL
MSMEG_6025|M.smegmatis_MC2_155 LWEQKRRAAEAAAGIPASRRGRG-LATEVALARRESPNAGGRHLGLAHAL
MAB_1907|M.abscessus_ATCC_1997 LLDRARREEEAANGVPRRRQGAG-VATEIALARQDSPARGSRHLGFAKAL
TH_0334|M.thermoresistible__bu ELYARRAPEDDTERANWAIDGHANVVAEISAALNISRGRAAGRLQLAIDL
MUL_2679|M.ulcerans_Agy99 DLFRLRLSQHG-NREDWVADTCDAVAAEVAAALNTSVAMGHSNLRYARAM
* . :. *:: * . : . .* * :
Mb3101|M.bovis_AF2122/97 VYEMPHTLAALDCGALS-EWRATLIVRESACLDVADRRALDAELCGDPGD
Rv3074|M.tuberculosis_H37Rv VYEMPHTLAALDCGALS-EWRATLIVRESACLDVADRRALDAELCGDPGD
MMAR_1584|M.marinum_M VHEMPHTLAALECGLLS-EWRATLIVRESACLDIEHRRELDAELCGDPSG
MAV_3980|M.avium_104 VHEMPHTLAALECGALS-EWRATLIVRESACLDAEDRRALDAELCADPAG
Mflv_2586|M.gilvum_PYR-GCK MGEMPHTWAALECGALS-EWRATLIVRESACLSVEDRRRLDEELCADVSR
Mvan_4725|M.vanbaalenii_PYR-1 VNEMPHTLAALESGVLS-EWRANLIVRESACLSVEHRRQLDAELCADASG
MSMEG_6025|M.smegmatis_MC2_155 VDELPHTLAALRCGALS-EWRATLIARESACLSPELRRELDAELSADPSR
MAB_1907|M.abscessus_ATCC_1997 VNEMPHTLAALECGALS-EWRATILVRETAYLAVEDRQKIDVEMCAETSR
TH_0334|M.thermoresistible__bu RERLPRVAAVFAAGDIDFRMVSALVNRSRNVVDPDLLARLDAALAAWSPK
MUL_2679|M.ulcerans_Agy99 RERLPQLGAEFRAGGIDFRLFRTIVFRTDLITESDALAAVDARLAIKAPR
.:*: * : .* :. . :: * :* :.
Mb3101|M.bovis_AF2122/97 LEGMGDARVVAAARAIAYRLDPQAVVDRAANAENDRTVTIRPAPDTMTYL
Rv3074|M.tuberculosis_H37Rv LEGMGDARVVAAARAIAYRLDPQAVVDRAANAENDRTVTIRPAPDTMTYL
MMAR_1584|M.marinum_M LEGMGDARVAAAAKAIAYRLDPHAVVDRAAKAERERTVTIRPAPDTMTYL
MAV_3980|M.avium_104 LSGMGDARVAAAAKAIAYRLDPHAVVERAAKAENDRTVTIRPAPDTMTYL
Mflv_2586|M.gilvum_PYR-GCK FEGWGNKRVEAEAKKIAARLDVAAVVERVDRAAAQARVSCRPAPNGMVYF
Mvan_4725|M.vanbaalenii_PYR-1 LEGWGNRRIEAEAKKIAARLDAAALVERARKAPEQRCVSCRPAPDNMLYV
MSMEG_6025|M.smegmatis_MC2_155 FDGWGDARVAAEAKKIACRLNIDAVLDRSAKAEKDRRVTIRPAPDAMTKL
MAB_1907|M.abscessus_ATCC_1997 LRGLGDTRLAAEAKRLAYRLDAQAVVRRARRAESERRVSLRPAPDTMTYL
TH_0334|M.thermoresistible__bu WMKLSGPTLNERIDMWVERFDPTGVRE-PRSPGEDRYVVVTPAGQGMVDV
MUL_2679|M.ulcerans_Agy99 WPSMTSWKLATEVDRVVAKFDRDAVRR-SRRDAADRYVDCAPLEPGMALV
. : . ::: .: : * * * .
Mb3101|M.bovis_AF2122/97 TALLPVAQGVSVYAALTRAADTRCD--GRSRGQVMADTLVERVTGR----
Rv3074|M.tuberculosis_H37Rv TALLPVAQGVSVYAALTRAADTRCD--GRSRGQVMADTLVERVTGR----
MMAR_1584|M.marinum_M TALLPVAQGISVYAALRRAADTRCD--GRSRGQVMADTLVERVTGR----
MAV_3980|M.avium_104 TALLPVAQGVSVYAALRREADTRGD--GRPRGQVMADTLVERVTGR----
Mflv_2586|M.gilvum_PYR-GCK TVLLPLAQGIGMYAALKHHADTTFD--GRSRGQVMADTAFERITGR----
Mvan_4725|M.vanbaalenii_PYR-1 TVLLPMTHGVAVYAACNRAADTTFD--GRTRDQVMADTIYERVTGR----
MSMEG_6025|M.smegmatis_MC2_155 TVLLPLKQGVAVYAALHQAAMVNAD--DRNRGQVMADTLVERVTGR----
MAB_1907|M.abscessus_ATCC_1997 TALLPVKQGVAVYAALKRTADASMDP-VRGQGQIMADTLVERVTGV----
TH_0334|M.thermoresistible__bu SARLTFEAGFAFXTRLDQIAATVCRDDPRTADQRRADAMAAMSEGQNRLV
MUL_2679|M.ulcerans_Agy99 NRQVFSATAEALARRLDELAKTVCADDPRTVVQRRADALGTLAAGQDRLI
. : . .. . * . * * **: *
Mb3101|M.bovis_AF2122/97 ------------DAAVPTPIAVNLVMSDETLLGAANTPAQLCGYGPIPAA
Rv3074|M.tuberculosis_H37Rv ------------DAAVPTPIAVNLVMSDETLLGAANTPAQLCGYGPIPAA
MMAR_1584|M.marinum_M ------------DAAVPTPIAVNLVLTDESLLGADSAPADVCGYGPIPAA
MAV_3980|M.avium_104 ------------RSTVPTPVAVNLVLSDETLLGGADAPGEISGYGPIPAA
Mflv_2586|M.gilvum_PYR-GCK ------------SAGTAVPVALNLVMADTTLAGDDDCPGWLDGYGPVPAG
Mvan_4725|M.vanbaalenii_PYR-1 ------------SAAEPVSVALNLVMADTTLFGDDEAPGWAQGYGPVPAA
MSMEG_6025|M.smegmatis_MC2_155 ------------PAHAPVPVNLNLVMADTTLFGEDDQPGWVQGYGPVPAE
MAB_1907|M.abscessus_ATCC_1997 ------------SAAAAVPVGVNITVSDEALLGGGDEPATITGHGLVPAA
TH_0334|M.thermoresistible__bu CGCGSEDCPADPADTAATRLVINVIAEQATVEGRSDNPGYLPGYGAVPAS
MUL_2679|M.ulcerans_Agy99 CDCGRTDCPAAGAPQQPSRVVIHVVAGCQTVDGAGEAPGVLPGDGIIPAE
. : ::: :: * . *. * * :**
Mb3101|M.bovis_AF2122/97 VARTMVASAVTDQRSRATLRRLYAHPQAGALVSMESRARLFPRGLAAFIE
Rv3074|M.tuberculosis_H37Rv VARTMVASAVTDQRSRATLRRLYAHPQAGALVSMESRARLFPRGLAAFIE
MMAR_1584|M.marinum_M VARTMVADAVADGRSRATLRRLYAHPRAGALVAMESRARLFPRGLAAFIE
MAV_3980|M.avium_104 VARRMVANAAADPRSRATLRRLYAHPRAGALVAMESRARLFPQGLARFIG
Mflv_2586|M.gilvum_PYR-GCK FCRALTGDAVADKGARATLRRLYRHPRSGQLVAMESRARLFPKGLATLID
Mvan_4725|M.vanbaalenii_PYR-1 VVRDLVSDAVTDAKAKATLRRLYRHPKSGQLVAMESRSWLFPKGLATFIG
MSMEG_6025|M.smegmatis_MC2_155 VARRMVADATLDENTKAAVRRLFRHPKSGQLVAMESRSRIFPKGLATFIG
MAB_1907|M.abscessus_ATCC_1997 VARRLISEAVS-AEAKVLVRRLYRRCTTGALVKAESRSRLFPRGLAELID
TH_0334|M.thermoresistible__bu ILRAKAATATLRPVALPQPCAEAGYRPS--------------AALTRFIR
MUL_2679|M.ulcerans_Agy99 IVRELAKSAKLQPMSTP-ILAETGYVPS--------------PALMDFVR
. * * : : .* ::
Mb3101|M.bovis_AF2122/97 LRDQRCRTPYCDAPIRHR--DHAHPWADGGPTSAHNGLGTCERCNYAKQA
Rv3074|M.tuberculosis_H37Rv LRDQRCRTPYCDAPIRHR--DHAHPWADGGPTSAHNGLGTCERCNYAKQA
MMAR_1584|M.marinum_M LRDQRCRTPYCDAPIRHR--DHARPWAKGGPTTADNGLGSCERCNYAKEA
MAV_3980|M.avium_104 LRDQRCRTPYCDAPIRHR--DHAQPWADGGATSAGNGLGLCEHCNYVKET
Mflv_2586|M.gilvum_PYR-GCK RRDQTCRTPYCDAPIRHH--DHATPDRAGGKTSAENGLGECAACNYAKEA
Mvan_4725|M.vanbaalenii_PYR-1 LRDQSCRTPYCDAPIRHH--DHAVPDREGGPTSALNGLGECQACNYAKEA
MSMEG_6025|M.smegmatis_MC2_155 LRDQTCRTPYCDALIRHR--DHAVPHHDGGPTTAHNGLGTCEACNYAKEA
MAB_1907|M.abscessus_ATCC_1997 LRDQTCRTPYCDAPIRHH--DHVVGSMRGGPTALDNGQGLCERCNYVKET
TH_0334|M.thermoresistible__bu CRDLTCRFPGCDAPAAVCQIDHTIPYPAG-PTHPSNLKLLCVFHCRQAEL
MUL_2679|M.ulcerans_Agy99 ARDLTCRAPGCDRPATQCDVDHTIPYSDGGATHPSNLKCLCRKHHLLKTF
** ** * ** **. * * * *
Mb3101|M.bovis_AF2122/97 PGWRVSTSVDENHTHTAE----FITPTG--------SRHRSGAPPHLP--
Rv3074|M.tuberculosis_H37Rv PGWRVSTSVDENHTHTAE----FITPTG--------SRHRSGAPPHLP--
MMAR_1584|M.marinum_M YGWRVETSMHETHTHTAE----FTTPTG--------TSYRSGAPPRVQ--
MAV_3980|M.avium_104 SGWTVSAGVDETHTHTAL----FTTPTG--------QTYRSTAPPRAP--
Mflv_2586|M.gilvum_PYR-GCK PGWQVSAGTQ-DGSHTAR----WVTPTG--------AVHYSIAPALPGPP
Mvan_4725|M.vanbaalenii_PYR-1 PGWHVTTTDT-DGEHTAT----FCTPTG--------AKYFSIAPPAPGTP
MSMEG_6025|M.smegmatis_MC2_155 PGWSVIITETSDGEHIAE----YVTPTG--------AVYRSTAPPLPGRP
MAB_1907|M.abscessus_ATCC_1997 AGWNVAPVPG-ADRHTVE----FTTPTG--------TAYRSTAPPLP---
TH_0334|M.thermoresistible__bu RFTHDQHKHQSS---CLP---AYFQRP---------HGPATRRPPSARG-
MUL_2679|M.ulcerans_Agy99 WGWHDEQLPDATVIWSLPDGQTYVTTPGSAWLLPGLFAPSPELPPPPRSE
: . . *.
Mb3101|M.bovis_AF2122/97 -AVTVSELEVRIGIALARYAA---------------
Rv3074|M.tuberculosis_H37Rv -AVTVSELEVRIGIALARYAA---------------
MMAR_1584|M.marinum_M -TVTASELEVRVGISLARHAA---------------
MAV_3980|M.avium_104 -AITMSTVEVRVAVAFARHAA---------------
Mflv_2586|M.gilvum_PYR-GCK VRRRISDTEGRLSIDLITFDKPDAA-----------
Mvan_4725|M.vanbaalenii_PYR-1 VSRR-SIVEGELSIDIVTFLAA--------------
MSMEG_6025|M.smegmatis_MC2_155 VRHTLSLVETGLTIDLVTFDAA--------------
MAB_1907|M.abscessus_ATCC_1997 ------------------------------------
TH_0334|M.thermoresistible__bu ----LR-----EAVPRQGVDP-------RRVSGQ--
MUL_2679|M.ulcerans_Agy99 ATGSLRKPRRDDAQTRPNSRPKLGRTHCDRTQPQHD