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VLPLDPATRAAQLVDRIAELERVKAAAAAEQAHAAVLLDRARREEEAANGVPRRRQGAGVATEIALARQD SPARGSRHLGFAKALVNEMPHTLAALECGALSEWRATILVRETAYLAVEDRQKIDVEMCAETSRLRGLGD TRLAAEAKRLAYRLDAQAVVRRARRAESERRVSLRPAPDTMTYLTALLPVKQGVAVYAALKRTADASMDP VRGQGQIMADTLVERVTGVSAAAAVPVGVNITVSDEALLGGGDEPATITGHGLVPAAVARRLISEAVSAE AKVLVRRLYRRCTTGALVKAESRSRLFPRGLAELIDLRDQTCRTPYCDAPIRHHDHVVGSMRGGPTALDN GQGLCERCNYVKETAGWNVAPVPGADRHTVEFTTPTGTAYRSTAPPLP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1907 | - | - | 100% (398) | hypothetical protein MAB_1907 |
| M. abscessus ATCC 19977 | MAB_4752 | - | 2e-19 | 26.94% (412) | hypothetical protein MAB_4752 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1413c | - | 1e-137 | 63.73% (397) | hypothetical protein Mb1413c |
| M. gilvum PYR-GCK | Mflv_2586 | - | 1e-117 | 54.04% (396) | hypothetical protein Mflv_2586 |
| M. tuberculosis H37Rv | Rv1378c | - | 1e-137 | 63.73% (397) | hypothetical protein Rv1378c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1584 | - | 1e-138 | 63.04% (395) | hypothetical protein MMAR_1584 |
| M. avium 104 | MAV_3980 | - | 1e-137 | 62.72% (397) | hypothetical protein MAV_3980 |
| M. smegmatis MC2 155 | MSMEG_6025 | - | 1e-124 | 57.43% (397) | hypothetical protein MSMEG_6025 |
| M. thermoresistible (build 8) | TH_0334 | - | 2e-13 | 26.10% (364) | HNH endonuclease |
| M. ulcerans Agy99 | MUL_2679 | - | 2e-20 | 26.87% (402) | 13e12 repeat-containing protein |
| M. vanbaalenii PYR-1 | Mvan_4725 | - | 1e-117 | 54.80% (396) | hypothetical protein Mvan_4725 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1413c|M.bovis_AF2122/97 MGNLDLLLHLSGRIVKGCRPLGSVALARCGPAVRWPWWPRPAILEHMFDL
Rv1378c|M.tuberculosis_H37Rv MGNLDLLLRLSGRIVKGCRPLGSVALARCGPAVRWPRWPRPAILEHMFDL
MMAR_1584|M.marinum_M ------------------------------------------------MF
MAV_3980|M.avium_104 --------------------------------------------------
MAB_1907|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2586|M.gilvum_PYR-GCK ------------------------------------------------MF
Mvan_4725|M.vanbaalenii_PYR-1 ------------------------------------------------MF
MSMEG_6025|M.smegmatis_MC2_155 --------------------------------------MSVRGCSVWHMF
TH_0334|M.thermoresistible__bu --------------------------------------------------
MUL_2679|M.ulcerans_Agy99 ------------------------------------------------MD
Mb1413c|M.bovis_AF2122/97 VSLAGVDSRDDEASLTARIAELERVKSAAAAGQARAAAALDKLRRCNEAD
Rv1378c|M.tuberculosis_H37Rv VSLAGVDSRDDEASLTARIAELERVKSAAAAGQARAAAALDKLRRCNEAD
MMAR_1584|M.marinum_M ESLAAVDPAADQAALVERIAELETVKSAAAAGQARAAAALDTARRAAESA
MAV_3980|M.avium_104 ---MAVDPAAGESALIERISELETLKCAAAAAQARAAAALDAARRAAEAA
MAB_1907|M.abscessus_ATCC_1997 --MLPLDPATRAAQLVDRIAELERVKAAAAAEQAHAAVLLDRARREEEAA
Mflv_2586|M.gilvum_PYR-GCK ESLFDIDEGASQAELRAVVERCERLKSAAAAAQARATALWAAKRAAAEEA
Mvan_4725|M.vanbaalenii_PYR-1 ESMFDVDETASQAELRAAVERLERLKSQAAAAQARATALWAAKRQLAEES
MSMEG_6025|M.smegmatis_MC2_155 ESLFDIDPQASEAELRDRIEQFERMKSAAAAAQATASVLWEQKRRAAEAA
TH_0334|M.thermoresistible__bu -----MFESLDDGAVVDSIAAASREQSAACGREMLAIGELYARRAPEDDT
MUL_2679|M.ulcerans_Agy99 QHIIEYVFDTDDSAPLTRITAAARAEARAAAERLAAIGDLFRLRLSQHG-
. : :. *.. . * * .
Mb1413c|M.bovis_AF2122/97 AGVPARRRGRG-VASEVALARRDSPARGGRHLGFAKALVYEMPHTLAALE
Rv1378c|M.tuberculosis_H37Rv AGVPARRRGRG-VASEVALARRDSPARGGRHLGFAKALVYEMPHTLAALE
MMAR_1584|M.marinum_M AGVPAARRGRG-LANEIALARRDSPARGSRHLGFAKALVHEMPHTLAALE
MAV_3980|M.avium_104 AGVPAARRGRG-VASEVALARRDSPARGGRHLGFAKALVHEMPHTLAALE
MAB_1907|M.abscessus_ATCC_1997 NGVPRRRQGAG-VATEIALARQDSPARGSRHLGFAKALVNEMPHTLAALE
Mflv_2586|M.gilvum_PYR-GCK AGVPVRRRGKG-LASEVALARRDAPVKGGQHLGFAKALMGEMPHTWAALE
Mvan_4725|M.vanbaalenii_PYR-1 AGVRAHHRGKG-LASEVALARRDAPVKGNQHLGFAKALVNEMPHTLAALE
MSMEG_6025|M.smegmatis_MC2_155 AGIPASRRGRG-LATEVALARRESPNAGGRHLGLAHALVDELPHTLAALR
TH_0334|M.thermoresistible__bu ERANWAIDGHANVVAEISAALNISRGRAAGRLQLAIDLRERLPRVAAVFA
MUL_2679|M.ulcerans_Agy99 NREDWVADTCDAVAAEVAAALNTSVAMGHSNLRYARAMRERLPQLGAEFR
:. *:: * . : . .* * : .:*: * :
Mb1413c|M.bovis_AF2122/97 VGRLS-EWRATLIVRESACLDVEDRRALDAELCADMSALDGMGDARIAAA
Rv1378c|M.tuberculosis_H37Rv VGRLS-EWRATLIVRESACLDVEDRRALDAELCADMSALDGMGDARIAAA
MMAR_1584|M.marinum_M CGLLS-EWRATLIVRESACLDIEHRRELDAELCGDPSGLEGMGDARVAAA
MAV_3980|M.avium_104 CGALS-EWRATLIVRESACLDAEDRRALDAELCADPAGLSGMGDARVAAA
MAB_1907|M.abscessus_ATCC_1997 CGALS-EWRATILVRETAYLAVEDRQKIDVEMCAETSRLRGLGDTRLAAE
Mflv_2586|M.gilvum_PYR-GCK CGALS-EWRATLIVRESACLSVEDRRRLDEELCADVSRFEGWGNKRVEAE
Mvan_4725|M.vanbaalenii_PYR-1 SGVLS-EWRANLIVRESACLSVEHRRQLDAELCADASGLEGWGNRRIEAE
MSMEG_6025|M.smegmatis_MC2_155 CGALS-EWRATLIARESACLSPELRRELDAELSADPSRFDGWGDARVAAE
TH_0334|M.thermoresistible__bu AGDIDFRMVSALVNRSRNVVDPDLLARLDAALAAWSPKWMKLSGPTLNER
MUL_2679|M.ulcerans_Agy99 AGGIDFRLFRTIVFRTDLITESDALAAVDARLAIKAPRWPSMTSWKLATE
* :. . :: * : :* :. . . :
Mb1413c|M.bovis_AF2122/97 ARAIAYRLDAQAVVERAARAETERTVTIRPAPDTMTWVTALLPVARGVSV
Rv1378c|M.tuberculosis_H37Rv ARAIAYRLDAQAVVERAARAETERTVTIRPAPDTMTWVTALLPVARGVSV
MMAR_1584|M.marinum_M AKAIAYRLDPHAVVDRAAKAERERTVTIRPAPDTMTYLTALLPVAQGISV
MAV_3980|M.avium_104 AKAIAYRLDPHAVVERAAKAENDRTVTIRPAPDTMTYLTALLPVAQGVSV
MAB_1907|M.abscessus_ATCC_1997 AKRLAYRLDAQAVVRRARRAESERRVSLRPAPDTMTYLTALLPVKQGVAV
Mflv_2586|M.gilvum_PYR-GCK AKKIAARLDVAAVVERVDRAAAQARVSCRPAPNGMVYFTVLLPLAQGIGM
Mvan_4725|M.vanbaalenii_PYR-1 AKKIAARLDAAALVERARKAPEQRCVSCRPAPDNMLYVTVLLPMTHGVAV
MSMEG_6025|M.smegmatis_MC2_155 AKKIACRLNIDAVLDRSAKAEKDRRVTIRPAPDAMTKLTVLLPLKQGVAV
TH_0334|M.thermoresistible__bu IDMWVERFDPTGVRE-PRSPGEDRYVVVTPAGQGMVDVSARLTFEAGFAF
MUL_2679|M.ulcerans_Agy99 VDRVVAKFDRDAVRR-SRRDAADRYVDCAPLEPGMALVNRQVFSATAEAL
. ::: .: : * * * .. : . ..
Mb1413c|M.bovis_AF2122/97 YAALKRAADTTFD--DRTRGQVMADTLVERVTGQ----------------
Rv1378c|M.tuberculosis_H37Rv YAALKRAADTTFD--DRTRGQVMADTLVERVTGQ----------------
MMAR_1584|M.marinum_M YAALRRAADTRCD--GRSRGQVMADTLVERVTGR----------------
MAV_3980|M.avium_104 YAALRREADTRGD--GRPRGQVMADTLVERVTGR----------------
MAB_1907|M.abscessus_ATCC_1997 YAALKRTADASMDP-VRGQGQIMADTLVERVTGV----------------
Mflv_2586|M.gilvum_PYR-GCK YAALKHHADTTFD--GRSRGQVMADTAFERITGR----------------
Mvan_4725|M.vanbaalenii_PYR-1 YAACNRAADTTFD--GRTRDQVMADTIYERVTGR----------------
MSMEG_6025|M.smegmatis_MC2_155 YAALHQAAMVNAD--DRNRGQVMADTLVERVTGR----------------
TH_0334|M.thermoresistible__bu XTRLDQIAATVCRDDPRTADQRRADAMAAMSEGQNRLVCGCGSEDCPADP
MUL_2679|M.ulcerans_Agy99 ARRLDELAKTVCADDPRTVVQRRADALGTLAAGQDRLICDCGRTDCPAAG
. * . * * **: *
Mb1413c|M.bovis_AF2122/97 PAEAAQPVAVNLVLSDETLLAGDRAPAVVDGYGPIPAAVARNLVRDAVAD
Rv1378c|M.tuberculosis_H37Rv PAEAAQPVAVNLVLSDETLLAGDRAPAVVDGYGPIPAAVARNLVRDAVAD
MMAR_1584|M.marinum_M DAAVPTPIAVNLVLTDESLLGADSAPADVCGYGPIPAAVARTMVADAVAD
MAV_3980|M.avium_104 RSTVPTPVAVNLVLSDETLLGGADAPGEISGYGPIPAAVARRMVANAAAD
MAB_1907|M.abscessus_ATCC_1997 SAAAAVPVGVNITVSDEALLGGGDEPATITGHGLVPAAVARRLISEAVS-
Mflv_2586|M.gilvum_PYR-GCK SAGTAVPVALNLVMADTTLAGDDDCPGWLDGYGPVPAGFCRALTGDAVAD
Mvan_4725|M.vanbaalenii_PYR-1 SAAEPVSVALNLVMADTTLFGDDEAPGWAQGYGPVPAAVVRDLVSDAVTD
MSMEG_6025|M.smegmatis_MC2_155 PAHAPVPVNLNLVMADTTLFGEDDQPGWVQGYGPVPAEVARRMVADATLD
TH_0334|M.thermoresistible__bu ADTAATRLVINVIAEQATVEGRSDNPGYLPGYGAVPASILRAKAATATLR
MUL_2679|M.ulcerans_Agy99 APQQPSRVVIHVVAGCQTVDGAGEAPGVLPGDGIIPAEIVRELAKSAKLQ
. : ::: :: . *. * * :** . * *
Mb1413c|M.bovis_AF2122/97 TRSRATLRRLYRHPRSGALVAMESRARRFPKGLAAFIGLRDQRCRMPYCD
Rv1378c|M.tuberculosis_H37Rv TRSRATLRRLYRHPRSGALVAMESRARRFPKGLAAFIGLRDQRCRMPYCD
MMAR_1584|M.marinum_M GRSRATLRRLYAHPRAGALVAMESRARLFPRGLAAFIELRDQRCRTPYCD
MAV_3980|M.avium_104 PRSRATLRRLYAHPRAGALVAMESRARLFPQGLARFIGLRDQRCRTPYCD
MAB_1907|M.abscessus_ATCC_1997 AEAKVLVRRLYRRCTTGALVKAESRSRLFPRGLAELIDLRDQTCRTPYCD
Mflv_2586|M.gilvum_PYR-GCK KGARATLRRLYRHPRSGQLVAMESRARLFPKGLATLIDRRDQTCRTPYCD
Mvan_4725|M.vanbaalenii_PYR-1 AKAKATLRRLYRHPKSGQLVAMESRSWLFPKGLATFIGLRDQSCRTPYCD
MSMEG_6025|M.smegmatis_MC2_155 ENTKAAVRRLFRHPKSGQLVAMESRSRIFPKGLATFIGLRDQTCRTPYCD
TH_0334|M.thermoresistible__bu PVALPQPCAEAGYRPS--------------AALTRFIRCRDLTCRFPGCD
MUL_2679|M.ulcerans_Agy99 PMSTP-ILAETGYVPS--------------PALMDFVRARDLTCRAPGCD
: : .* :: ** ** * **
Mb1413c|M.bovis_AF2122/97 APIRHR--DHAQPHHRGGPTTATNGLGSCERCNYVKEAPGWRVSTDTDET
Rv1378c|M.tuberculosis_H37Rv APIRHR--DHAQPHHRGGPTTATNGLGSCERCNYVKEAPGWRVSTDTDET
MMAR_1584|M.marinum_M APIRHR--DHARPWAKGGPTTADNGLGSCERCNYAKEAYGWRVETSMHET
MAV_3980|M.avium_104 APIRHR--DHAQPWADGGATSAGNGLGLCEHCNYVKETSGWTVSAGVDET
MAB_1907|M.abscessus_ATCC_1997 APIRHH--DHVVGSMRGGPTALDNGQGLCERCNYVKETAGWNVAP-VPGA
Mflv_2586|M.gilvum_PYR-GCK APIRHH--DHATPDRAGGKTSAENGLGECAACNYAKEAPGWQVSAGTQ-D
Mvan_4725|M.vanbaalenii_PYR-1 APIRHH--DHAVPDREGGPTSALNGLGECQACNYAKEAPGWHVTTTDT-D
MSMEG_6025|M.smegmatis_MC2_155 ALIRHR--DHAVPHHDGGPTTAHNGLGTCEACNYAKEAPGWSVIITETSD
TH_0334|M.thermoresistible__bu APAAVCQIDHTIPYPAG-PTHPSNLKLLCVFHCRQAELRFTHDQHKHQSS
MUL_2679|M.ulcerans_Agy99 RPATQCDVDHTIPYSDGGATHPSNLKCLCRKHHLLKTFWGWHDEQLPDAT
**. * * * *
Mb1413c|M.bovis_AF2122/97 GRHTAE-----FTTPTG----MYYHCTAPPLPGPLEIDV-SQVEARIGVA
Rv1378c|M.tuberculosis_H37Rv GRHTAE-----FTTPTG----MYYHCTAPPLPGPLEIDV-SQVEARIGVA
MMAR_1584|M.marinum_M HTHTAE-----FTTPTG----TSYRSGAP--PRVQTVTA-SELEVRVGIS
MAV_3980|M.avium_104 HTHTAL-----FTTPTG----QTYRSTAP--PRAPAITM-STVEVRVAVA
MAB_1907|M.abscessus_ATCC_1997 DRHTVE-----FTTPTG----TAYRSTAPPLP------------------
Mflv_2586|M.gilvum_PYR-GCK GSHTAR-----WVTPTG----AVHYSIAPALPGPPVRRRISDTEGRLSID
Mvan_4725|M.vanbaalenii_PYR-1 GEHTAT-----FCTPTG----AKYFSIAPPAPGTPVSRR-SIVEGELSID
MSMEG_6025|M.smegmatis_MC2_155 GEHIAE-----YVTPTG----AVYRSTAPPLPGRPVRHTLSLVETGLTID
TH_0334|M.thermoresistible__bu ---CLP---AYFQRP---------HGPATRRPPSARG-----LR-----E
MUL_2679|M.ulcerans_Agy99 VIWSLPDGQTYVTTPGSAWLLPGLFAPSPELPPPPRSEATGSLRKPRRDD
* :. *
Mb1413c|M.bovis_AF2122/97 LTHLHAA-----------------
Rv1378c|M.tuberculosis_H37Rv LTHLHAA-----------------
MMAR_1584|M.marinum_M LAR-HAA-----------------
MAV_3980|M.avium_104 FAR-HAA-----------------
MAB_1907|M.abscessus_ATCC_1997 ------------------------
Mflv_2586|M.gilvum_PYR-GCK LITFDKPDAA--------------
Mvan_4725|M.vanbaalenii_PYR-1 IVTFLAA-----------------
MSMEG_6025|M.smegmatis_MC2_155 LVTFDAA-----------------
TH_0334|M.thermoresistible__bu AVPRQGVDP-------RRVSGQ--
MUL_2679|M.ulcerans_Agy99 AQTRPNSRPKLGRTHCDRTQPQHD