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ALPDLVLVHGGEHAGDCWDLVIAELRRQEPGLRTLAVDLPGHGNKPGDLATVTIADWVDSVIADIEEAGL GDIVIVGHSMAGVTVPGVVAKLGSSRVREMVLATAFVPPQGSAIADTLGGPLAVFARRAARIGRPMKIPA PAARWAFCNGMTAAQRRLTMSKLQAESARVPGEPVDRSGLPADVPRTWILTTRDRALSVASQHASIAALG GVETVIPVDACHEVMFSHPERLAQILIERCRLRGVGIR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2604 | - | - | 100% (249) | hydrolase, alpha/beta fold family protein, putative |
| M. avium 104 | MAV_1894 | - | 1e-80 | 74.48% (192) | hypothetical protein MAV_1894 |
| M. avium 104 | MAV_3771 | - | 6e-11 | 32.39% (176) | hydrolase, alpha/beta fold family protein, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0046c | - | 7e-05 | 31.73% (104) | hydrolase |
| M. gilvum PYR-GCK | Mflv_2476 | - | 6e-11 | 27.63% (257) | esterase EstC, putative |
| M. tuberculosis H37Rv | Rv0045c | - | 7e-05 | 31.73% (104) | hydrolase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2946c | - | 3e-08 | 24.81% (262) | Alpha/beta hydrolase fold |
| M. marinum M | MMAR_0064 | - | 3e-05 | 33.65% (104) | hydrolase |
| M. smegmatis MC2 155 | MSMEG_1797 | - | 8e-15 | 30.25% (238) | salicylate esterase |
| M. thermoresistible (build 8) | TH_2893 | - | 7e-12 | 28.92% (249) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3299 | - | 9e-05 | 32.00% (100) | hypothetical protein MUL_3299 |
| M. vanbaalenii PYR-1 | Mvan_4177 | - | 9e-14 | 29.53% (254) | esterase EstC, putative |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2476|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4177|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0046c|M.bovis_AF2122/97 ---MLSD---DELTGLDEFALLAENAEQAGVNGPLPEVERVQAGA----I
Rv0045c|M.tuberculosis_H37Rv ---MLSD---DELTGLDEFALLAENAEQAGVNGPLPEVERVQAGA----I
MMAR_0064|M.marinum_M ----MTDSFPDDLTGLTEFDLLAENAEQAGVTGPLPEVERIEVGAAETRI
TH_2893|M.thermoresistible__bu --------------------------------------------------
MAV_2604|M.avium_104 --------------------------------------------------
MSMEG_1797|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2946c|M.abscessus_ATCC_199 ------------------------------------MIAESRAEYGGVVT
MUL_3299|M.ulcerans_Agy99 MRPTLAAAALAGASGLVGWGGARALARRIERNPDPFPRERLLAEPQGERV
Mflv_2476|M.gilvum_PYR-GCK ------------------MRFILVHGGFHAAWCWERTAAALRA--LGHDV
Mvan_4177|M.vanbaalenii_PYR-1 ------------------MRFVLVHGGFHAAWCWERTIDALQA--LGHDA
Mb0046c|M.bovis_AF2122/97 SALR---------WGGSAPRVIFLHGGGQNAHTWD---TVIVG--LGEPA
Rv0045c|M.tuberculosis_H37Rv SALR---------WGGSAPRVIFLHGGGQNAHTWD---TVIVG--LGEPA
MMAR_0064|M.marinum_M SALR---------WGGRAPRVIFLHGGGQNAHTWD---TVIVG--LGEPA
TH_2893|M.thermoresistible__bu ----------------MAKPILLVHGAFSGSWVWDQVVAELAS--CGVQA
MAV_2604|M.avium_104 ---------------MALPDLVLVHGGEHAGDCWDLVIAELRRQEPGLRT
MSMEG_1797|M.smegmatis_MC2_155 -----------------MADFVIVHGSWHDGTLLEPVAAAIRG--LGHRA
MAB_2946c|M.abscessus_ATCC_199 RVLS---------VPGGGPPIVLLHGYSDSALTWRPVLARLAS--AGRAA
MUL_3299|M.ulcerans_Agy99 AITRPDGTVLHALVAGRGTPVILVHGYCASLTEWNFVWDELLAR--GLRV
.:::** : * .
Mflv_2476|M.gilvum_PYR-GCK TAVDLPGHGALADQE----STLANRRDAIVAAMQAGDEKCVLVGHSGGGF
Mvan_4177|M.vanbaalenii_PYR-1 VAVDLPGHGDRVDEE----STLANRREAVVAAMQAGGGKCVLVGHSGGGF
Mb0046c|M.bovis_AF2122/97 LAVDLPGHGHSAWREDGNYSPQLNSETLAPVLRELAPGAEFVVGMSLGGL
Rv0045c|M.tuberculosis_H37Rv LAVDLPGHGHSAWREDGNYSPQLNSETLAPVLRELAPGAEFVVGMSLGGL
MMAR_0064|M.marinum_M LAVDLPGHGHSAWRQDGDYSPQHNADALVPALRELASEAEFVVGMSLGGL
TH_2893|M.thermoresistible__bu RTVELSSRKP--------DGTLARDAHVVRDALKQFDQPAVLVGHSYGG-
MAV_2604|M.avium_104 LAVDLPGHGNKPGDLAT-VTIADWVDSVIADIEEAGLGDIVIVGHSMAGV
MSMEG_1797|M.smegmatis_MC2_155 YAPTVAGHGHGADTD---VSIDDGVQSVIDYCRTRDLREIVLVGHSLGGT
MAB_2946c|M.abscessus_ATCC_199 IAVDLPGFGHAAPRP---PGPLLAQFDVFADAVLAAAGPAVLVGNSLGAA
MUL_3299|M.ulcerans_Agy99 IAFDQRGHGRSTLGAEG-IGSEPMADDLAAVLQHFDLRDGVLVGHSMGGF
: . .:** * ..
Mflv_2476|M.gilvum_PYR-GCK DATLAADARP-DLVSHITYLAAALPREGRTYPEAMAMRDDDNGPVELGED
Mvan_4177|M.vanbaalenii_PYR-1 DATLAADARP-DLVHHIVYLAAALPREGRTYPEAMAMRDAEQGPAELGDE
Mb0046c|M.bovis_AF2122/97 TAIRLAAMAP-DLVGELVLVDVTPS----ALQRHAELTAEQRGTVALMHG
Rv0045c|M.tuberculosis_H37Rv TAIRLAAMAP-DLVGELVLVDVTPS----ALQRHAELTAEQRGTVALMHG
MMAR_0064|M.marinum_M TAIRLGALAP-ELVDELVLIDVTPS----ALQRHAEMTAEQRGTVALMHG
TH_2893|M.thermoresistible__bu AVITEASADN-DHVAHLIYVCAALPQAGESVSDVLARDPDPQG-------
MAV_2604|M.avium_104 TVPGVVAKLGSSRVREMVLATAFVP------PQGSAIADTLGGPLAVFAR
MSMEG_1797|M.smegmatis_MC2_155 IIARVAEEIP-DRITRLIFWSAFVPRPGRSITEEVEQPSTPAAEK-----
MAB_2946c|M.abscessus_ATCC_199 TAVRAAARRE-NEVKALIALDDPLN-SRHLIARIVRRWSVPEVFWAWVSR
MUL_3299|M.ulcerans_Agy99 VSIRALLDHG-ALAQRLRAVVLFATWAGRVLDGAPQNRLQIPLLERGILQ
:
Mflv_2476|M.gilvum_PYR-GCK FDGDVGEMLGYLHFDDTGAMKFADFDGAWKYFYHDCDEETARWAFERLGP
Mvan_4177|M.vanbaalenii_PYR-1 FDGDVGEMLGYLNFDEDGAMTFADFEGAWKYFYHDCDEATARWAFERLGP
Mb0046c|M.bovis_AF2122/97 -EREFPSFQAMLDLTIAAAPHRDVKSLRRGVFHNSRRLDNGNWVWRYDAI
Rv0045c|M.tuberculosis_H37Rv -EREFPSFQAMLDLTIAAAPHRDVKSLRRGVFHNSRRLDNGNWVWRYDAI
MMAR_0064|M.marinum_M -EREFPSFQAMLDLTVAAAPHREVKALRRGVFHNSRRLENGNWAWRYDAI
TH_2893|M.thermoresistible__bu ------DLAPALEVREDGTATMKR-DAARQALFNDATEEQFESVVDKLGP
MAV_2604|M.avium_104 ------------RAARIGRPMKIPAPAARWAFCNGMTAAQRRLTMSKLQA
MSMEG_1797|M.smegmatis_MC2_155 ------------QAPATGSSETLSLQVWRDVFVPDVDPEQAATWHALLSP
MAB_2946c|M.abscessus_ATCC_199 MPVPAGTLRRAARYFVPKMLYGPGVAADPEVVAYWCELISGPSAVARLGR
MUL_3299|M.ulcerans_Agy99 RLLRSRTIAVLFGAAQCGARPSPAMISGIPRVVPSTSRPARTAPTHRAGV
.
Mflv_2476|M.gilvum_PYR-GCK ERFGDTT-----VTPVSVPNFWAADLPRSFIVCEQDQAMPRWLADTVARR
Mvan_4177|M.vanbaalenii_PYR-1 ERFGDTT-----VTPVSVPDFWAADLPRSFIVCEQDRSMPRWLADTVARR
Mb0046c|M.bovis_AF2122/97 RTFGDFAGLWDDVDALSAPITLVRGGSSGFVTDQDTAELHRRATHFRG--
Rv0045c|M.tuberculosis_H37Rv RTFGDFAGLWDDVDALSAPITLVRGGSSGFVTDQDTAELHRRATHFRG--
MMAR_0064|M.marinum_M RAFPDFAVLWDDVDALAAPVTLVRGGKSGFVSDEDIAELRGRAKGFRG--
TH_2893|M.thermoresistible__bu HAMGTLS--------EPVTGLGWQQHPATYVIALRDQMFSVALQEEFASH
MAV_2604|M.avium_104 ESARVPG-------EPVDRSGLPADVPRTWILTTRDRALSVASQHASIAA
MSMEG_1797|M.smegmatis_MC2_155 EPRRPKT------ERLDLRRFYRSTLPMHYIDAVDDRALPRGLDREAMIE
MAB_2946c|M.abscessus_ATCC_199 DACRYAH------EALGSHSGIEVSCPTLVVHGGRDRIIPIHSSGALQQQ
MUL_3299|M.ulcerans_Agy99 LARGSLS---------TAGRDLGAGGGDGGLLGSHHPAQPLAPAGRRNPG
:
Mflv_2476|M.gilvum_PYR-GCK LG--VDQLTIDASHSPFLSRPREFADLLVHATTTTPVAPLRPL----
Mvan_4177|M.vanbaalenii_PYR-1 LG--VEQLTIDASHSPFLSRPRELAELLVRATTTTPVSPLVPH----
Mb0046c|M.bovis_AF2122/97 -----VHIVEKSGHSVQSDQPRALIEIVRGVLDTR------------
Rv0045c|M.tuberculosis_H37Rv -----VHIVEKSGHSVQSDQPRALIEIVRGVLDTR------------
MMAR_0064|M.marinum_M -----AQTVENSGHSVQSDQPRVLVEILRGVLGGR------------
TH_2893|M.thermoresistible__bu VG---TVAKIDTGHGPMATRPAELAEIIATAAR--------------
MAV_2604|M.avium_104 LGGVETVIPVDACHEVMFSHPERLAQILIERCRLRGVGIR-------
MSMEG_1797|M.smegmatis_MC2_155 RLKNVRVHRVRGGHEVLFTDPAGIAAVIVEAGVS-------------
MAB_2946c|M.abscessus_ATCC_199 IPGSELVILPASGHCPQLDNPDEVTRLIVDFCDRISEPRQPDAAHSG
MUL_3299|M.ulcerans_Agy99 CPAGHRARRGTPAELGGGRRAGRSRRILCGAAVLMRGHAAGVWR---
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