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MGSLDGKVAFITGAGRGQGRAHAVRLATDGADIVALDICHDIDSIDYPNASPEDLDETVKLVEKEGRRIV ARQADVRDADAVDKVVADGLGEFGRLDIVIANAGVVRLSPGGDRRQTFRDIIDVNLIGVWNTVEAATPAL IDGGRGGSIVITSSSAGLKGTGTDRAGGQAYTASKRGLVGLMQVWANELAQHSIRVNTIHPTGVATGMVM NDTMAALFEAGDTAVSAMQNALPIQILMPEDIANAVAFLVSDEARFITGTAWPLDAGFAVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1921 | - | - | 100% (271) | carveol dehydrogenase ((+)-trans-carveol dehydrogenase) |
| M. avium 104 | MAV_2623 | - | e-125 | 82.95% (264) | carveol dehydrogenase |
| M. avium 104 | MAV_1913 | - | e-123 | 81.44% (264) | carveol dehydrogenase ((+)-trans-carveol dehydrogenase) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2771 | - | 3e-75 | 54.14% (266) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_3996 | - | 5e-77 | 55.43% (276) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. tuberculosis H37Rv | Rv2750 | - | 3e-75 | 54.14% (266) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_02565 | fabG | 6e-22 | 31.44% (264) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. abscessus ATCC 19977 | MAB_3081 | - | 6e-80 | 56.04% (273) | Short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_1965 | fabG | 3e-75 | 55.39% (269) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2687 | - | 3e-76 | 56.34% (268) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. thermoresistible (build 8) | TH_0236 | - | 1e-123 | 80.95% (273) | PROBABLE DEHYDROGENASE |
| M. ulcerans Agy99 | MUL_3392 | fabG | 9e-75 | 55.02% (269) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_3394 | - | 3e-78 | 54.04% (272) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2771|M.bovis_AF2122/97 --------------------------------------------------
Rv2750|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_2687|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1965|M.marinum_M --------------------------------------------------
MUL_3392|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3996|M.gilvum_PYR-GCK --------------------------------------------------
MAB_3081|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1921|M.avium_104 --------------------------------------------------
TH_0236|M.thermoresistible__bu --------------------------------------------------
Mvan_3394|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_02565|M.leprae_Br4923 MAPKCSSDLFSQIVSSGPGSFVAKQLGVPRPETLRRYRPSDAPLCGSLLI
Mb2771|M.bovis_AF2122/97 ----------------------------------------MIDR---PLE
Rv2750|M.tuberculosis_H37Rv ----------------------------------------MIDR---PLE
MSMEG_2687|M.smegmatis_MC2_155 ----------------------------------------MSDTA--PLS
MMAR_1965|M.marinum_M ----------------------------------------MSRPLDGPLS
MUL_3392|M.ulcerans_Agy99 ----------------------------------------MSRPLDGPLS
Mflv_3996|M.gilvum_PYR-GCK ---------------------------------------------MAELT
MAB_3081|M.abscessus_ATCC_1997 ---------------------------------------------MGKLD
MAV_1921|M.avium_104 ---------------------------------------------MGSLD
TH_0236|M.thermoresistible__bu ---------------------------------------------MGNLE
Mvan_3394|M.vanbaalenii_PYR-1 ---------------------------------------------MGSLD
MLBr_02565|M.leprae_Br4923 GGDGRLVEPLRATLEKDYDLVSNNLGGRWTDSFGGLVFDATGITAPAELK
*
Mb2771|M.bovis_AF2122/97 GKVAFITGAARGLGRAHAVRLA----------------------------
Rv2750|M.tuberculosis_H37Rv GKVAFITGAARGLGRAHAVRLA----------------------------
MSMEG_2687|M.smegmatis_MC2_155 GKVAFITGAARGQGRAEAVRLA----------------------------
MMAR_1965|M.marinum_M GRVAFITGAARGQGRAHALRLA----------------------------
MUL_3392|M.ulcerans_Agy99 GRVAFITGAARGQGRAHALRLA----------------------------
Mflv_3996|M.gilvum_PYR-GCK GKVAFITGAARGQGRAHAVKLA----------------------------
MAB_3081|M.abscessus_ATCC_1997 GKVAFITGAARGQGRAHAIKLA----------------------------
MAV_1921|M.avium_104 GKVAFITGAGRGQGRAHAVRLA----------------------------
TH_0236|M.thermoresistible__bu GKVAFITGAARGQGRAHAVRLA----------------------------
Mvan_3394|M.vanbaalenii_PYR-1 GRVAFITGVARGQGRSHAVRLA----------------------------
MLBr_02565|M.leprae_Br4923 GLHNFFTPLLRNLGRCARVVVIGTTPDATTSTDERIAQRALEGFSRSLGK
* *:* *. **. : :
Mb2771|M.bovis_AF2122/97 --ADGANIIAVDICEQIASVPYPLSTAD----------------------
Rv2750|M.tuberculosis_H37Rv --ADGANIIAVDICEQIASVPYPLSTAD----------------------
MSMEG_2687|M.smegmatis_MC2_155 --ADGADIIAVDLCAQIASVPYPLATPD----------------------
MMAR_1965|M.marinum_M --RDGADVIAVDLCDQIASVPYPLGTAE----------------------
MUL_3392|M.ulcerans_Agy99 --RDGADVIAVDLCDQIASVPYPLGTAE----------------------
Mflv_3996|M.gilvum_PYR-GCK --SEGADIIALDLCAQIDSVPYPLATPD----------------------
MAB_3081|M.abscessus_ATCC_1997 --SEGASIIAVDICAQIPSVEYPMATTE----------------------
MAV_1921|M.avium_104 --TDGADIVALDICHDIDSIDYPNASPE----------------------
TH_0236|M.thermoresistible__bu --SEGADIIALDICADIDSMDYPNASPA----------------------
Mvan_3394|M.vanbaalenii_PYR-1 --ADGADIIGVDICSDIASNGYPMATPA----------------------
MLBr_02565|M.leprae_Br4923 ELRRGATVALVYLSPDAKPAATGLESTMRFILSAKSAYVNGQVFYVGAAD
** : : :. : . :.
Mb2771|M.bovis_AF2122/97 ---------DLAATVELVEDAGGGIVARQGDVRDRA--------------
Rv2750|M.tuberculosis_H37Rv ---------DLAATVELVEDAGGGIVARQGDVRDRA--------------
MSMEG_2687|M.smegmatis_MC2_155 ---------DLATTAELVEKAGGRIVTRQADVRDEP--------------
MMAR_1965|M.marinum_M ---------ELATTVKLVEDTGARIVASQADVRDRE--------------
MUL_3392|M.ulcerans_Agy99 ---------ELATTVKLVEDTGARIVASQADVRDRE--------------
Mflv_3996|M.gilvum_PYR-GCK ---------DMAATVKLVEEAGGRIATYEADVRDRD--------------
MAB_3081|M.abscessus_ATCC_1997 ---------DLDLTVKEVDALGRAISAHETDVRDRE--------------
MAV_1921|M.avium_104 ---------DLDETVKLVEKEGRRIVARQADVRDAD--------------
TH_0236|M.thermoresistible__bu ---------DLEETAKLVEGTGRSIVARQADVRDAD--------------
Mvan_3394|M.vanbaalenii_PYR-1 ---------ELEETVALVEAQGAKMLGSVADVRDFS--------------
MLBr_02565|M.leprae_Br4923 STPPTNWDRPLENKVAIVTGAARGIGAAIAEVVARDGARVVAIDVESAAE
: .. * . : :*
Mb2771|M.bovis_AF2122/97 ----------------------SLSVALQAGLDEFG-RLDIVVANAGIAM
Rv2750|M.tuberculosis_H37Rv ----------------------SLSVALQAGLDEFG-RLDIVVANAGIAM
MSMEG_2687|M.smegmatis_MC2_155 ----------------------ELAAALAAGLDEFG-RLDIVVANAGIAP
MMAR_1965|M.marinum_M ----------------------ALAAALQAGIDELG-QVDIVVANAGIAP
MUL_3392|M.ulcerans_Agy99 ----------------------ALAAALQAGIDELG-QVDIVVANAGIAP
Mflv_3996|M.gilvum_PYR-GCK ----------------------AVKAVVRDGTEKFGDRLDIVIANAGIAP
MAB_3081|M.abscessus_ATCC_1997 ----------------------ALQAAFDAGVHDLG-PVDIVVANAGIAT
MAV_1921|M.avium_104 ----------------------AVDKVVADGLGEFG-RLDIVIANAGVVR
TH_0236|M.thermoresistible__bu ----------------------AVDEVVREGVERFG-RLDIVVANAGIVR
Mvan_3394|M.vanbaalenii_PYR-1 ----------------------AVKGALDAGVEHFG-RLDIVCANAGIAT
MLBr_02565|M.leprae_Br4923 ALDETANRVGGTTLSLDVTADDAVDKITEHLHDYQGGHADILVNNAGITR
: * **: ***:.
Mb2771|M.bovis_AF2122/97 MQ-------AGDDGWRDVIDVNLTGVFHTVQVAIPTLIEQGTGGSIVLIS
Rv2750|M.tuberculosis_H37Rv MQ-------AGDDGWRDVIDVNLTGVFHTVQVAIPTLIEQGTGGSIVLIS
MSMEG_2687|M.smegmatis_MC2_155 ML-------SGPEGWRDVIDVNLTGVHHTVEVAIPTLVEQGDGGAIVLIS
MMAR_1965|M.marinum_M MQ-------SGDDGWRDVIDVNLSGAYYTVEVAIPTMIEQGRGGSIVLIS
MUL_3392|M.ulcerans_Agy99 MQ-------SGDDGWRDVIDVNLSGAYYTVEVAIPTMIEQGRGGSIVLIS
Mflv_3996|M.gilvum_PYR-GCK MA-------AAD-AWQDVIDVNLTGVYNTIDVAMKPMVKFGNGGAIVLTS
MAB_3081|M.abscessus_ATCC_1997 LTPE-----CGDDGWRDVLDVNLTGVYHTIEVARPSMVQRGAGGSIVLTS
MAV_1921|M.avium_104 LSPG----GDRRQTFRDIIDVNLIGVWNTVEAATPALIDGGRGGSIVITS
TH_0236|M.thermoresistible__bu LSSDEP--SQRRQIFRDIIDVNLVGVWNTVEAAIPHVINGGQGGSIVITS
Mvan_3394|M.vanbaalenii_PYR-1 MSFRELTDAEDLEMWTDVLDVNLVGTFHTAKAAIPHLIAGGRGGSMVFTS
MLBr_02565|M.leprae_Br4923 DKLLAN---MDDCRWDAVLEVNLLAPQRLTEGLVGNGS-ISKGGRVIVLS
: :::*** . . . ** ::. *
Mb2771|M.bovis_AF2122/97 SAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANHLAPQNIRVNSVHPCG
Rv2750|M.tuberculosis_H37Rv SAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANHLAPQNIRVNSVHPCG
MSMEG_2687|M.smegmatis_MC2_155 SVAGLVGIGGGDRGSLGYTAAKHGIVGLMRAYANHLAPHSIRVNSVHPTG
MMAR_1965|M.marinum_M SAAGLVGISSADAGAIGYAASKHALVGLMRVYANLLAPHSIRVNSLHPSG
MUL_3392|M.ulcerans_Agy99 SAAGLVGISSADAGAIGYVASKHALVGLMRVYANLLAPHSIRVNSLHPSG
Mflv_3996|M.gilvum_PYR-GCK SVAGLVGIGAPLGGSVGYAAAKHGIVGIMRVYANFLAQYSIRVNSVHPAG
MAB_3081|M.abscessus_ATCC_1997 SVAGLTGMVMDNPGGLAYTAAKHGLVGLMRSYANMLAPHNIRVNTIHPSG
MAV_1921|M.avium_104 SSAGLKGTGTDRAGGQAYTASKRGLVGLMQVWANELAQHSIRVNTIHPTG
TH_0236|M.thermoresistible__bu SSAGLKGTGTDRAGGQAYAAAKRGLVGLMQVWANQLGPHSIRVNTIHPTG
Mvan_3394|M.vanbaalenii_PYR-1 STAGLRGFGGMQGGGLGYAASKHGIVGLMRALANALAPHNIRVNTVHPTA
MLBr_02565|M.leprae_Br4923 SMAGIAGN----RGQTNYATAKAGVIGLTQALAPGLAEKGITINAVAPGF
* **: * * *.::* .::*: : * *. .* :*:: *
Mb2771|M.bovis_AF2122/97 VDTPMINNEFFQQWLT--TADMDAPHNLGNALPVELVQPTDIANAVAWLA
Rv2750|M.tuberculosis_H37Rv VDTPMINNEFFQQWLT--TADMDAPHNLGNALPVELVQPTDIANAVAWLA
MSMEG_2687|M.smegmatis_MC2_155 VDTPMIDNEFTRGWLAHITEETGRPVDMGNALPVQAIDADDVANAVAWLV
MMAR_1965|M.marinum_M VDTPMINNEFIRRWLADLVAETGSGPGAGNALPVQILQADDIAGALAWLV
MUL_3392|M.ulcerans_Agy99 VDPPMINNEFIRHWLADLVAETGSGPGAGNALPVQILQADDIAGALAWLV
Mflv_3996|M.gilvum_PYR-GCK VNTPMIDNDFTRSWLDGMAQQSQGGPDMGNALPVQTLEPEDIANAVYWLV
MAB_3081|M.abscessus_ATCC_1997 VATPMLINPVTEKLFADGSPEGMS--DTGNALPVVLMEPEDMANTVAWLV
MAV_1921|M.avium_104 VATGMVMNDTMAALFE---AGDTAVSAMQNALPIQILMPEDIANAVAFLV
TH_0236|M.thermoresistible__bu VATGMVMNETMAKLFE---QGDEALSAMQNVLPIQILQPEDIAEAVAWLV
Mvan_3394|M.vanbaalenii_PYR-1 VNTMMAVNPAMTEFLE---HYPDGGPHLQNPMPVDLLEPEDISAAVAYLV
MLBr_02565|M.leprae_Br4923 IETQMTAAIPLATREVG----------RRLNSLLQGGLPVDVAETIAYFA
: . * : . *:: :: ::.
Mb2771|M.bovis_AF2122/97 SEEARYVTGVTLPVDAGFVNKR
Rv2750|M.tuberculosis_H37Rv SEEARYVTGVTLPVDAGFVNKR
MSMEG_2687|M.smegmatis_MC2_155 SDQARYVTGVTLPVDAGIVNKR
MMAR_1965|M.marinum_M SDEARYITGVALPVDAGCVNKR
MUL_3392|M.ulcerans_Agy99 SDEARYITGVALPVDAGCVNKR
Mflv_3996|M.gilvum_PYR-GCK SDAARYVTGITLPVDAGFVNKR
MAB_3081|M.abscessus_ATCC_1997 SEDARYITGVALPVDAGFTNRR
MAV_1921|M.avium_104 SDEARFITGTAWPLDAGFAVR-
TH_0236|M.thermoresistible__bu SDAGRFITGTAWPLDAGFSVR-
Mvan_3394|M.vanbaalenii_PYR-1 SDAARYVTGVTFPVDAGFCNKL
MLBr_02565|M.leprae_Br4923 IPASNAVTGNVIRVCGQAMLGA
.. :** . : .