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VAFITGAARGQGRAHAVRLAAEGADIVAVDICRDIDSMDYPNATPDDLDETIKLVENQGRRIIAHQADVR DADALKQAVNEGVREFGRLDIVLANAGIIRLGGEGDRSQIFRDIVDVNLIGVWNTVEAAIPALIDGGRGG SIVLTSSSAGLKGTGTDRAGGQAYTAAKRGLVGLMQVWANELAQYWIRVNTIHPTGVATGMVMNETMGKL LEANDTAVAAMQNALPIQILMPEDIAGAVAWLVSDEAKFITGVAWPLDAGFAVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2623 | - | - | 100% (264) | carveol dehydrogenase |
| M. avium 104 | MAV_1913 | - | e-137 | 90.53% (264) | carveol dehydrogenase ((+)-trans-carveol dehydrogenase) |
| M. avium 104 | MAV_1921 | - | e-125 | 82.95% (264) | carveol dehydrogenase ((+)-trans-carveol dehydrogenase) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2771 | - | 5e-75 | 56.06% (264) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_3996 | - | 9e-77 | 55.09% (265) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. tuberculosis H37Rv | Rv2750 | - | 5e-75 | 56.06% (264) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01740 | - | 1e-18 | 33.50% (203) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3081 | - | 3e-78 | 57.52% (266) | Short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_1965 | fabG | 3e-75 | 56.23% (265) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5812 | - | 1e-75 | 55.47% (265) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_0236 | - | 1e-117 | 78.20% (266) | PROBABLE DEHYDROGENASE |
| M. ulcerans Agy99 | MUL_3392 | fabG | 3e-74 | 55.85% (265) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_3394 | - | 2e-77 | 55.09% (265) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2623|M.avium_104 ------------MAFITGAARGQGRAHAVRLAAEGADIVAVDICRDIDSM
TH_0236|M.thermoresistible__bu -----MGNLEGKVAFITGAARGQGRAHAVRLASEGADIIALDICADIDSM
MSMEG_5812|M.smegmatis_MC2_155 -----MVSLDGKVAFITGAARGQGRSHAVRLASEGADIIGVDICADIASA
Mvan_3394|M.vanbaalenii_PYR-1 -----MGSLDGRVAFITGVARGQGRSHAVRLAADGADIIGVDICSDIASN
Mb2771|M.bovis_AF2122/97 ---MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIASV
Rv2750|M.tuberculosis_H37Rv ---MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIASV
MMAR_1965|M.marinum_M MSRPLDGPLSGRVAFITGAARGQGRAHALRLARDGADVIAVDLCDQIASV
MUL_3392|M.ulcerans_Agy99 MSRPLDGPLSGRVAFITGAARGQGRAHALRLARDGADVIAVDLCDQIASV
Mflv_3996|M.gilvum_PYR-GCK -----MAELTGKVAFITGAARGQGRAHAVKLASEGADIIALDLCAQIDSV
MAB_3081|M.abscessus_ATCC_1997 -----MGKLDGKVAFITGAARGQGRAHAIKLASEGASIIAVDICAQIPSV
MLBr_01740|M.leprae_Br4923 -MVKTAQYFVGKRCFVTGAASGIGRATALRLAAYGAELYLTDR-------
.*:**.* * **: *::** **.: *
MAV_2623|M.avium_104 DYPNATPDDLDETIKLVENQGRRIIAHQADVRDADALKQAVNEGVREFG-
TH_0236|M.thermoresistible__bu DYPNASPADLEETAKLVEGTGRSIVARQADVRDADAVDEVVREGVERFG-
MSMEG_5812|M.smegmatis_MC2_155 GYPMAGREELDETVALVEAHGGKMMSAVADVRDYGALKTALDAGVDHFG-
Mvan_3394|M.vanbaalenii_PYR-1 GYPMATPAELEETVALVEAQGAKMLGSVADVRDFSAVKGALDAGVEHFG-
Mb2771|M.bovis_AF2122/97 PYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQAGLDEFG-
Rv2750|M.tuberculosis_H37Rv PYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQAGLDEFG-
MMAR_1965|M.marinum_M PYPLGTAEELATTVKLVEDTGARIVASQADVRDREALAAALQAGIDELG-
MUL_3392|M.ulcerans_Agy99 PYPLGTAEELATTVKLVEDTGARIVASQADVRDREALAAALQAGIDELG-
Mflv_3996|M.gilvum_PYR-GCK PYPLATPDDMAATVKLVEEAGGRIATYEADVRDRDAVKAVVRDGTEKFGD
MAB_3081|M.abscessus_ATCC_1997 EYPMATTEDLDLTVKEVDALGRAISAHETDVRDREALQAAFDAGVHDLG-
MLBr_01740|M.leprae_Br4923 -----HCDGLAQTVSEARALGAQVPEYRALDISDYDEVAAFGADIHARHP
: * . * : . .. .
MAV_2623|M.avium_104 RLDIVLANAGIIRLGGE----GDRSQIFRDIVDVNLIGVWNTVEAAIPAL
TH_0236|M.thermoresistible__bu RLDIVVANAGIVRLSSDEP--SQRRQIFRDIIDVNLVGVWNTVEAAIPHV
MSMEG_5812|M.smegmatis_MC2_155 RLDIVCANAGIAAMAFRELTIEEDLQMWADVVDVNLVGSFHTAKAAIPHL
Mvan_3394|M.vanbaalenii_PYR-1 RLDIVCANAGIATMSFRELTDAEDLEMWTDVLDVNLVGTFHTAKAAIPHL
Mb2771|M.bovis_AF2122/97 RLDIVVANAGIAMMQ-------AGDDGWRDVIDVNLTGVFHTVQVAIPTL
Rv2750|M.tuberculosis_H37Rv RLDIVVANAGIAMMQ-------AGDDGWRDVIDVNLTGVFHTVQVAIPTL
MMAR_1965|M.marinum_M QVDIVVANAGIAPMQ-------SGDDGWRDVIDVNLSGAYYTVEVAIPTM
MUL_3392|M.ulcerans_Agy99 QVDIVVANAGIAPMQ-------SGDDGWRDVIDVNLSGAYYTVEVAIPTM
Mflv_3996|M.gilvum_PYR-GCK RLDIVIANAGIAPMA-------AAD-AWQDVIDVNLTGVYNTIDVAMKPM
MAB_3081|M.abscessus_ATCC_1997 PVDIVVANAGIATLTP-----ECGDDGWRDVLDVNLTGVYHTIEVARPSM
MLBr_01740|M.leprae_Br4923 SMDIVMNIAGVSVWGTVDR---LTHDQWSNVVAINLMGPIHIIETFVPAI
:*** **: : ::: :** * .. :
MAV_2623|M.avium_104 IDGGRGGSIVLTSSSAGLKGTGTDRAGGQAYTAAKRGLVGLMQVWANELA
TH_0236|M.thermoresistible__bu INGGQGGSIVITSSSAGLKGTGTDRAGGQAYAAAKRGLVGLMQVWANQLG
MSMEG_5812|M.smegmatis_MC2_155 IAGERGGSIVFTSSTAGLRGFGGMQGGGLGYAASKHGIVGLMRTLANALA
Mvan_3394|M.vanbaalenii_PYR-1 IAGGRGGSMVFTSSTAGLRGFGGMQGGGLGYAASKHGIVGLMRALANALA
Mb2771|M.bovis_AF2122/97 IEQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANHLA
Rv2750|M.tuberculosis_H37Rv IEQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANHLA
MMAR_1965|M.marinum_M IEQGRGGSIVLISSAAGLVGISSADAGAIGYAASKHALVGLMRVYANLLA
MUL_3392|M.ulcerans_Agy99 IEQGRGGSIVLISSAAGLVGISSADAGAIGYVASKHALVGLMRVYANLLA
Mflv_3996|M.gilvum_PYR-GCK VKFGNGGAIVLTSSVAGLVGIGAPLGGSVGYAAAKHGIVGIMRVYANFLA
MAB_3081|M.abscessus_ATCC_1997 VQRGAGGSIVLTSSVAGLTGMVMDNPGGLAYTAAKHGLVGLMRSYANMLA
MLBr_01740|M.leprae_Br4923 LAAGRGGHLVNVSSAAGLVALP----WHAAYSASKYGLRGLSEVLRFDLA
: ** :* ** *** . .* *:* .: *: . *.
MAV_2623|M.avium_104 QYWIRVNTIHPTGVATGMVM----------NETMGKLLEA---NDTAVAA
TH_0236|M.thermoresistible__bu PHSIRVNTIHPTGVATGMVM----------NETMAKLFEQ---GDEALSA
MSMEG_5812|M.smegmatis_MC2_155 PHRIRVNTVHPTAVNTMMAV----------NPAMTAFLEN---YPDGGPH
Mvan_3394|M.vanbaalenii_PYR-1 PHNIRVNTVHPTAVNTMMAV----------NPAMTEFLEH---YPDGGPH
Mb2771|M.bovis_AF2122/97 PQNIRVNSVHPCGVDTPMIN----------NEFFQQWLT--TADMDAPHN
Rv2750|M.tuberculosis_H37Rv PQNIRVNSVHPCGVDTPMIN----------NEFFQQWLT--TADMDAPHN
MMAR_1965|M.marinum_M PHSIRVNSLHPSGVDTPMIN----------NEFIRRWLADLVAETGSGPG
MUL_3392|M.ulcerans_Agy99 PHSIRVNSLHPSGVDPPMIN----------NEFIRHWLADLVAETGSGPG
Mflv_3996|M.gilvum_PYR-GCK QYSIRVNSVHPAGVNTPMID----------NDFTRSWLDGMAQQSQGGPD
MAB_3081|M.abscessus_ATCC_1997 PHNIRVNTIHPSGVATPMLI----------NPVTEKLFAD--GSPEGMSD
MLBr_01740|M.leprae_Br4923 RYRIGVSVVVPGAVRTPLVDTIEIAGVDRQDPRFSRWVDRFRGHAVSAER
* *. : * .* . : : . .
MAV_2623|M.avium_104 MQNALPIQILM---------------------------PEDIAGAVAWLV
TH_0236|M.thermoresistible__bu MQNVLPIQILQ---------------------------PEDIAEAVAWLV
MSMEG_5812|M.smegmatis_MC2_155 LQNPMPVELLE---------------------------PEDISAAIAYLV
Mvan_3394|M.vanbaalenii_PYR-1 LQNPMPVDLLE---------------------------PEDISAAVAYLV
Mb2771|M.bovis_AF2122/97 LGNALPVELVQ---------------------------PTDIANAVAWLA
Rv2750|M.tuberculosis_H37Rv LGNALPVELVQ---------------------------PTDIANAVAWLA
MMAR_1965|M.marinum_M AGNALPVQILQ---------------------------ADDIAGALAWLV
MUL_3392|M.ulcerans_Agy99 AGNALPVQILQ---------------------------ADDIAGALAWLV
Mflv_3996|M.gilvum_PYR-GCK MGNALPVQTLE---------------------------PEDIANAVYWLV
MAB_3081|M.abscessus_ATCC_1997 TGNALPVVLME---------------------------PEDMANTVAWLV
MLBr_01740|M.leprae_Br4923 AAEKILAGVAKNRYLIYTSHDIRVLYGFKRLAWWPYGVVMKQVNVVFTRA
: : . .: .
MAV_2623|M.avium_104 SDEAKFITGVAWPLDAGFAVR-----------
TH_0236|M.thermoresistible__bu SDAGRFITGTAWPLDAGFSVR-----------
MSMEG_5812|M.smegmatis_MC2_155 SDAAEYVTGVTFPVDAGFCNKL----------
Mvan_3394|M.vanbaalenii_PYR-1 SDAARYVTGVTFPVDAGFCNKL----------
Mb2771|M.bovis_AF2122/97 SEEARYVTGVTLPVDAGFVNKR----------
Rv2750|M.tuberculosis_H37Rv SEEARYVTGVTLPVDAGFVNKR----------
MMAR_1965|M.marinum_M SDEARYITGVALPVDAGCVNKR----------
MUL_3392|M.ulcerans_Agy99 SDEARYITGVALPVDAGCVNKR----------
Mflv_3996|M.gilvum_PYR-GCK SDAARYVTGITLPVDAGFVNKR----------
MAB_3081|M.abscessus_ATCC_1997 SEDARYITGVALPVDAGFTNRR----------
MLBr_01740|M.leprae_Br4923 LRPSPATMRCVEPIKVGVYSQPRSGEGGKSGN
. . *:..* :