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ATTWDTLDRYIVISTDTHAGADLYGYKPYLPARLHDEFDAWAKAYASPFDDLIVATANRNWDHELRIGEM DADGVAAEVLLPNTVPPFFPTTPNITISLPRTRAEFEKRWAGVQAHNRWQVDFCSLAPDRRRGLIQIFPN DVELAMEEIRWGARQDCFGGVLIPPVSPGDSQVAPLFHTRYEPLWALCAELDLTVVQHAGAGSPEMPMDQ PASNAVLITEMALWAQRTLGHLILAGVFERYPTLRFVPTEQGTLWVPAQLGVLDAMVPTMKSDAHNRTYG MFGGSSVDALTLTPSEYVQRNCYLASELMPYDGAMIDFMGPDHIMWGSDYPHEEGFAPHSKLAIRWALHD RPEDACRKILGGNAARLYRFDLDKLIPVAAKIGPTVEEVRTPVPDTGYRAPAAFGYRPFEGGLALKRLAP QRG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3544 | - | - | 100% (424) | amidohydrolase |
| M. avium 104 | MAV_3541 | - | 3e-94 | 45.88% (388) | amidohydrolase |
| M. avium 104 | MAV_3540 | - | 5e-48 | 32.91% (395) | amidohydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4324 | - | 2e-15 | 26.61% (327) | amidohydrolase 2 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4820 | - | 2e-96 | 47.68% (388) | hypothetical protein MMAR_4820 |
| M. smegmatis MC2 155 | MSMEG_4837 | - | 4e-18 | 25.91% (413) | amidohydrolase 2 |
| M. thermoresistible (build 8) | TH_2827 | - | 1e-17 | 25.39% (319) | PUTATIVE amidohydrolase 2 |
| M. ulcerans Agy99 | MUL_0389 | - | 7e-97 | 47.68% (388) | hypothetical protein MUL_0389 |
| M. vanbaalenii PYR-1 | Mvan_0901 | - | 8e-24 | 29.73% (333) | amidohydrolase 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4324|M.gilvum_PYR-GCK -----MNRDDMILISVDDHIVEPPDMFKNHLSKKYLVEAP---RLVHNED
MSMEG_4837|M.smegmatis_MC2_155 -----MNKDDMILISVDDHIIEPPDMFKNHLPAKYRDEAP---RLVHNPD
MMAR_4820|M.marinum_M -------MDRYTVISADCHAGADLLDYREYLEAKYQDEFD---DWAKTFV
MUL_0389|M.ulcerans_Agy99 -------MDRYTVISADCHAGADLFDYREYLEAKYQDEFD---DWAKTFV
MAV_3544|M.avium_104 MATTWDTLDRYIVISTDTHAGADLYGYKPYLPARLHDEFD---AWAKAYA
Mvan_0901|M.vanbaalenii_PYR-1 ------MGSSTLIIDTDTHITEPPDLWTSRMSKSRWGNLIPEVKWVEEKQ
TH_2827|M.thermoresistible__bu -----VTAPALEIWDADNHLYEPTDAYTRHLPKQYRGAIQ----WIQVDG
: ..* * : : .
Mflv_4324|M.gilvum_PYR-GCK GSDTWQFRDV--VIPNVALNAVAGR-----PKEEYGLEPQGLDEIRPGCW
MSMEG_4837|M.smegmatis_MC2_155 GSDTWQFRDT--VIPNVALNAVAGR-----PKEEYGLEPQGLDEIRKGCY
MMAR_4820|M.marinum_M N----PFGDL--SEPDAEHNWDSDR-----RNAELDSDGVAGEVIFPNTV
MUL_0389|M.ulcerans_Agy99 N----PFGDL--SEPDAEHNWDSDR-----RNAELDSDGVAGEVIFPNTV
MAV_3544|M.avium_104 S----PFDDL--IVATANRNWDHEL-----RIGEMDADGVAAEVLLPNTV
Mvan_0901|M.vanbaalenii_PYR-1 GEYWCMDGQP--VFTVGTCIMVPGEDGKPVRSPRFPDYADRFSSMHPSAY
TH_2827|M.thermoresistible__bu LTKLMIKGRLTDTIPNPTYEVVASPGAWADYFRGINPEGKSLRELANPIR
. :
Mflv_4324|M.gilvum_PYR-GCK QVDERVKDMNAGGILGSMCFPSFPGFAGR--LFATE---DPEFSLALVQA
MSMEG_4837|M.smegmatis_MC2_155 DPNERVKDMNAGGVLATMNFPSFPGFAAR--LFATD---DEEFSLALVQA
MMAR_4820|M.marinum_M PP----------------FFPQG-SLAAP--PPSTAR--DLELRWAGLRA
MUL_0389|M.ulcerans_Agy99 PP----------------FFPQG-SLAAP--APSTAR--DLELRWAGLRA
MAV_3544|M.avium_104 PP----------------FFPTTPNITIS--LPRTRA--EFEKRWAGVQA
Mvan_0901|M.vanbaalenii_PYR-1 DAKARLEVMDAYGIQAAAIFPNLGFVGPN--IFAAAGPDALEFQTAALQA
TH_2827|M.thermoresistible__bu CPEEFRHAEQRLRLLDAQGIQACVMFPTTGGMLEERMLDDIELTHAVVHA
: . * * ::*
Mflv_4324|M.gilvum_PYR-GCK YNDWHVEEWCGAYPARFIPMTLPVIWDPEACAKEIRRNAARGVHS--LTF
MSMEG_4837|M.smegmatis_MC2_155 YNDWHIDEWCASNPGRFIPMAIPAIWNPGLAAAEVRRVAEKGVHS--LTF
MMAR_4820|M.marinum_M HNRWLAD-FCSLSPERRAGVGQILLGDVDEAVAEVAQIAKLGLRGGVLLP
MUL_0389|M.ulcerans_Agy99 HNRWLAD-FCSLSPERRAGVGQILLGDVDEAVAEVAQIAKLGLPGGVLLP
MAV_3544|M.avium_104 HNRWQVD-FCSLAPDRRRGLIQIFPNDVELAMEEIRWGARQDCFGGVLIP
Mvan_0901|M.vanbaalenii_PYR-1 YNDFLLD-WSSIAPDRLLSLALIPYWDVDAAVAEIERCAAAGHKG--LVS
TH_2827|M.thermoresistible__bu YNEWLLEEWTFDYAGRIFATPVITLPDVDKAVAELNWCVENGARAVLVNP
:* : : : . * : . *: . . . :
Mflv_4324|M.gilvum_PYR-GCK SENPSAMGYPSFHDFDHWKPMWDALVDTDTVLNVHIGSS-----------
MSMEG_4837|M.smegmatis_MC2_155 TENPSTLGYPSFHDLEYWRPLWQALVDTETVMNVHIGSS-----------
MMAR_4820|M.marinum_M GVAPG-TGIPALY-AEHWEPLWAACAQAGLVINHHGGNA-----------
MUL_0389|M.ulcerans_Agy99 GVAPG-TGIPALY-AEHWEPLWAACAQAGLVINHHGGNA-----------
MAV_3544|M.avium_104 PVSPGDSQVAPLF-HTRYEPLWALCAELDLTVVQHAGAG-----------
Mvan_0901|M.vanbaalenii_PYR-1 TGKPHEHGYKLLA-DRYWDPMWAAAQDANLSISFHVGGGNLSRHL----N
TH_2827|M.thermoresistible__bu RPVATITGHTTSMGQPYFDPFWHRVEQLGIPVLMHACDSGYDRYSRDWEG
. : *:* : : * .
Mflv_4324|M.gilvum_PYR-GCK -GRLAITAPDAPMDVMITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEG
MSMEG_4837|M.smegmatis_MC2_155 -GKLAITAPDAPMDVMITLQPMNIVQAAADLLWSAPIKEFPTLKIALSEG
MMAR_4820|M.marinum_M -GPSPIDGWGSSLAVWVYESHWWAHRALWHLIFSGVLDRYPDLTVVLTEQ
MUL_0389|M.ulcerans_Agy99 -GPSPIDGWGSSLAVLVYESHWWAHRALLHLIFSGVLDRYPDLTVVLTEQ
MAV_3544|M.avium_104 -SPEMPMDQPASNAVLITEMALWAQRTLGHLILAGVFERYPTLRFVPTEQ
Mvan_0901|M.vanbaalenii_PYR-1 DERTSVEGWRATLARLTTSFFLESGITLADLLMSGVLARYPKLRFVSVES
TH_2827|M.thermoresistible__bu KGGEYTPFKPDAFRTIVYEDARSILDTCAALVAHGVFTRHPGVRVGVVEN
. : *: : ..* : . *
Mflv_4324|M.gilvum_PYR-GCK GTGWIPYFLERVDRTYEMHS----TWTGQDFKG--------KLPSEVFRE
MSMEG_4837|M.smegmatis_MC2_155 GTGWIPYFLDRVDRTFEMHS----TWTHQNFGG--------KLPSEVFRE
MMAR_4820|M.marinum_M GTGWIPATLDSLDVAAARYR--RPNSAIARFAGPTAGSLPLQPSQYWARQ
MUL_0389|M.ulcerans_Agy99 GTGWIPATLDSLDVAAARYR--RPNSAIARFAGPTAGSLPLQPSQYWARQ
MAV_3544|M.avium_104 GTLWVPAQLGVLDAMVPTMKSDAHNRTYGMFGGSSVDALTLTPSEYVQRN
Mvan_0901|M.vanbaalenii_PYR-1 AVGWIPFLLESLDFHYKKYEP---WLERPEFAGN-----DMLPSDYFHRQ
TH_2827|M.thermoresistible__bu GGAWVPRLIDLFERVYKKMP--------NEFGAH---------PVEQFRE
. *:* : .: * . . *:
Mflv_4324|M.gilvum_PYR-GCK HFLTCFIADPVGVATRHQIGVDNICWEADYPHSDSMWP-GAPEQLDEVLK
MSMEG_4837|M.smegmatis_MC2_155 HFMTCFISDPVGVKNRHMIGIDNICWEMDYPHSDSMWP-GAPEELSAVFD
MMAR_4820|M.marinum_M CYVGASFLRPVECAQRHRIGVDRIMWGSDYPHMEGTAP-YSREALRHTFS
MUL_0389|M.ulcerans_Agy99 CYVGASFLRPVECAQRHRIGVDRIMWASDYPHMEGTAP-YSREALRHTFS
MAV_3544|M.avium_104 CYL-ASELMPYDGAMIDFMGPDHIMWGSDYPHEEGFAP-HSKLAIRWALH
Mvan_0901|M.vanbaalenii_PYR-1 VYANYWYED-LQPWHVAAIGEDNLMFETDYPHQTCLDKEEIQHSINEGLS
TH_2827|M.thermoresistible__bu HVWVNPFHEEDLSGLIDLIGADRVLFGSDFPHPEGLAE---PAKLTPEIA
:* *.: : *:** : :
Mflv_4324|M.gilvum_PYR-GCK ANNVPDDEINKMTYENAMRWYHWDPFTHIAKEQATVGALRKAAEGHDVSI
MSMEG_4837|M.smegmatis_MC2_155 TYDVPDDEINKITHENAMRLYHFDPFAHVPKEQATVGALRKAAEGHDVSI
MMAR_4820|M.marinum_M D--VDPDEVAAMVGGNAAAVYGFD-LQALAPLAARIGPTVTEVAEPLAAI
MUL_0389|M.ulcerans_Agy99 D--VDPDEVAAMVGGNAAAVYGFD-LQALAPLAARIGPTVTEVAEPLAAI
MAV_3544|M.avium_104 D--RPEDACRKILGGNAARLYRFD-LDKLIPVAAKIGPTVEEVRTPVPDT
Mvan_0901|M.vanbaalenii_PYR-1 G--VSETTKEKILWRNAASLFNMD-IAKLEKLT-----------------
TH_2827|M.thermoresistible__bu E--LPEPTIEAVMGGNLRELLTAVPHGR----------------------
: *
Mflv_4324|M.gilvum_PYR-GCK QALSHHKEGERGGGAGHFDALNAAARGNSGA
MSMEG_4837|M.smegmatis_MC2_155 RALS--KKDKTGASFADFQANAKAVSGARD-
MMAR_4820|M.marinum_M ----PADASSTAFEP-------DPIRAW---
MUL_0389|M.ulcerans_Agy99 ----PADASSTAFEP-------DPIRAW---
MAV_3544|M.avium_104 GYRAPAAFGYRPFEGGLALKRLAPQRG----
Mvan_0901|M.vanbaalenii_PYR-1 -------------------------------
TH_2827|M.thermoresistible__bu -------------------------------