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TDVDPYIIISADTHAELPTERYREYVDPEYREDFETYLAEKTAAAQAGGFIDEEFAQEWFSEHGEGIAGG WDVALRDKELDGDGVVGEVIFPDADAVTGVAGAPFGAGLGQSGDLDPGRAMAGARAHNRWLAELCSHSPE RRAGVAVVPILADVDAAVAEITRAAESGLRGGILIPARWVGYPPYHDRRYDKVWAACQDLQMPVHTHSGP APQEEYGGHLGIYVTEVRWWGARPLWFALWSGVFERFPGLRWGVTECGAFWANDLLWLMDTRYLREHSAK KMSHLMEGDLTMPPSAYFDRNCFIGATTTERRELARRYEIGVSNILWGNDFPHPEGTWPHTRDWLRRSFW DIPVEETRQMLGLAAAELYNFDLGALAPLAARIGPVPADLGQDDAVSIPKWEAARRTGRHWLTDAEPMPD LVQS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3540 | - | - | 100% (425) | amidohydrolase |
| M. avium 104 | MAV_3541 | - | 2e-74 | 39.35% (399) | amidohydrolase |
| M. avium 104 | MAV_3544 | - | 5e-48 | 32.91% (395) | amidohydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2441 | - | 1e-19 | 24.37% (398) | amidohydrolase 2 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4821 | - | 0.0 | 89.34% (422) | hypothetical protein MMAR_4821 |
| M. smegmatis MC2 155 | MSMEG_4837 | - | 9e-21 | 25.37% (402) | amidohydrolase 2 |
| M. thermoresistible (build 8) | TH_2827 | - | 2e-12 | 23.98% (367) | PUTATIVE amidohydrolase 2 |
| M. ulcerans Agy99 | MUL_0389 | - | 4e-72 | 39.35% (399) | hypothetical protein MUL_0389 |
| M. vanbaalenii PYR-1 | Mvan_2022 | - | 1e-18 | 24.49% (396) | amidohydrolase 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2441|M.gilvum_PYR-GCK -------MDKNDMILISVDDHIVEPPDMFKNHLSKKYL--------DEAP
Mvan_2022|M.vanbaalenii_PYR-1 -------MNRDDMILISVDDHIVEPPDMFKNHLPSKYL--------DEAP
MSMEG_4837|M.smegmatis_MC2_155 -------MNKDDMILISVDDHIIEPPDMFKNHLPAKYR--------DEAP
MAV_3540|M.avium_104 ------MTDVDPYIIISADTHAELPTERYREYVDPEYR--------EDFE
MMAR_4821|M.marinum_M MEARKAPNPLEPYVVISADCHAELPTEQYREYVDPDYR--------EDFE
MUL_0389|M.ulcerans_Agy99 ---------MDRYTVISADCHAGADLFDYREYLEAKYQ--------DEFD
TH_2827|M.thermoresistible__bu -------VTAPALEIWDADNHLYEPTDAYTRHLPKQYRGAIQWIQVDGLT
: ..* * : .:: .* :
Mflv_2441|M.gilvum_PYR-GCK RLVHNEDGSDTW---QFRDVVIPNVALNAVAGRPKEEYGLEPQGLDEIRP
Mvan_2022|M.vanbaalenii_PYR-1 RLVHNPDGSDTW---QFRDVVIPNVALNAVAGRPKEEYGLEPQGLDEIRP
MSMEG_4837|M.smegmatis_MC2_155 RLVHNPDGSDTW---QFRDTVIPNVALNAVAGRPKEEYGLEPQGLDEIRK
MAV_3540|M.avium_104 TYLAEKTAAA-----QAGGFIDEEFAQEWFSEHGEGIAGGWDVALRDKEL
MMAR_4821|M.marinum_M VYLAEKAAAS-----QVGGFIDEQFAQDWFSEHGEGIAGGWDVGLRDKEL
MUL_0389|M.ulcerans_Agy99 DWA--KTFVN-----PFGDLSEPDAEHNWDSDR------------RNAEL
TH_2827|M.thermoresistible__bu KLMIKGRLTDTIPNPTYEVVASPGAWADYFRGINPEGKSLRELANPIRCP
:
Mflv_2441|M.gilvum_PYR-GCK GCW-QVDERVKDMNAGGILGSMCFPSFPGFAGRLFATEDPEFSLALVQAY
Mvan_2022|M.vanbaalenii_PYR-1 GCW-QVDERVKDMNAGGILGSMCFPSFPGFAGRLFATEDAEFSLALVQAY
MSMEG_4837|M.smegmatis_MC2_155 GCY-DPNERVKDMNAGGVLATMNFPSFPGFAARLFATDDEEFSLALVQAY
MAV_3540|M.avium_104 DGD-GVVGEVIFPDADAVTGVAGAPFGAGLGQ--SGDLDPGRAMAGARAH
MMAR_4821|M.marinum_M DSD-GVVGEVIFPDADAVSGVAGAPFGAGLAQ--SGSLDPGRAMAGARAH
MUL_0389|M.ulcerans_Agy99 DSD-GVAGEVIFPNTVPPFFPQGSLAAPAPST--ARDLELR--WAGLRAH
TH_2827|M.thermoresistible__bu EEFRHAEQRLRLLDAQGIQACVMFPTTGGMLEERMLD-DIELTHAVVHAY
.: :: . : * :*:
Mflv_2441|M.gilvum_PYR-GCK NDWHVEEWCGAYPARFIPMTLPVIWDPEACAKEIRRNAARGVHS-LTFSE
Mvan_2022|M.vanbaalenii_PYR-1 NDWHVEEWCGAYPARFIPMTLPVIWDPVACAAEIRRNAARGVHS-LTFSE
MSMEG_4837|M.smegmatis_MC2_155 NDWHIDEWCASNPGRFIPMAIPAIWNPGLAAAEVRRVAEKGVHS-LTFTE
MAV_3540|M.avium_104 NRWLAELCSHSPERRAGVAVVPILADVDAAVAEITRAAESGLRGGILIP-
MMAR_4821|M.marinum_M NRWLAELCSHSPERRAGVAVVPILADVDAAVAEITRAAESGLRGGIMIP-
MUL_0389|M.ulcerans_Agy99 NRWLADFCSLSPERRAGVGQI-LLGDVDEAVAEVAQIAKLGLPGGVLLPG
TH_2827|M.thermoresistible__bu NEWLLEEWTFDYAGRIFATPVITLPDVDKAVAELNWCVENGARAVLVNPR
* * : * : : : .. *: . * . : .
Mflv_2441|M.gilvum_PYR-GCK -NPSAMGYPSFHDFDHWKPMWDALVDTDTVLNVHIGSSGRLAITA-----
Mvan_2022|M.vanbaalenii_PYR-1 -NPSAMGYPSFHDFEHWKPMWDALVDTDTVLNVHIGSSGRLAITA-----
MSMEG_4837|M.smegmatis_MC2_155 -NPSTLGYPSFHDLEYWRPLWQALVDTETVMNVHIGSSGKLAITA-----
MAV_3540|M.avium_104 --ARWVGYPPYHD-RRYDKVWAACQDLQMPVHTHSG---PAPQEE-----
MMAR_4821|M.marinum_M --ALWASYPPYHD-RRYDKVWAACQDLQMPVHTHVG---AAPQQE-----
MUL_0389|M.ulcerans_Agy99 -VAPGTGIPALYA-EHWEPLWAACAQAGLVINHHGGNAGPSPIDG-----
TH_2827|M.thermoresistible__bu PVATITGHTTSMGQPYFDPFWHRVEQLGIPVLMHACDSGYDRYSRDWEGK
. . .. : .* : : *
Mflv_2441|M.gilvum_PYR-GCK -------PDAPMDVMITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEGG
Mvan_2022|M.vanbaalenii_PYR-1 -------PDAPMDVMITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEGG
MSMEG_4837|M.smegmatis_MC2_155 -------PDAPMDVMITLQPMNIVQAAADLLWSAPIKEFPTLKIALSEGG
MAV_3540|M.avium_104 -------YGGHLGIYVTEVRWWGARPLWFALWSGVFERFPGLRWGVTECG
MMAR_4821|M.marinum_M -------YGEHLGIYVTEVRWWGVRPLWFALWSGVFERFPGLRWGATECG
MUL_0389|M.ulcerans_Agy99 -------WGSSLAVLVYESHWWAHRALLHLIFSGVLDRYPDLTVVLTEQG
TH_2827|M.thermoresistible__bu GGEYTPFKPDAFRTIVYEDARSILDTCAALVAHGVFTRHPGVRVGVVENG
: : . : : ..* : * *
Mflv_2441|M.gilvum_PYR-GCK TGWIP---YFLERVDRTYEMHSTWTG-------QDFKGKLPSEVFREHFL
Mvan_2022|M.vanbaalenii_PYR-1 TGWIP---YFLERVDRTYEMHSTWTG-------QDFKGKLPSEVFREHFL
MSMEG_4837|M.smegmatis_MC2_155 TGWIP---YFLDRVDRTFEMHSTWTH-------QNFGGKLPSEVFREHFM
MAV_3540|M.avium_104 AFWAN---DLLWLMDTRYLREHSAKK-MSHLMEGDLTMPPSAYFDRNCFI
MMAR_4821|M.marinum_M AFWAN---DLLWLMDTRYLREHSAKK-MSHLLEGDLTMPPSAYFDRNCFI
MUL_0389|M.ulcerans_Agy99 TGWIPATLDSLDVAAARYRRPNSAIARFAGPTAGSLPLQPSQYWARQCYV
TH_2827|M.thermoresistible__bu GAWVP---RLIDLFERVYKKMPNEFG------------AHPVEQFREHVW
* : : . . *:
Mflv_2441|M.gilvum_PYR-GCK TCFIADPVGVATRHQIGVDNICWEADYPHSDSMWPGAPEQLDEVLKANNV
Mvan_2022|M.vanbaalenii_PYR-1 TCFIADPVGVATRHQIGVDNICWEADYPHSDSMWPGAPEQLDEVLKVNNV
MSMEG_4837|M.smegmatis_MC2_155 TCFISDPVGVKNRHMIGIDNICWEMDYPHSDSMWPGAPEELSAVFDTYDV
MAV_3540|M.avium_104 GATTTERRELARRYEIGVSNILWGNDFPHPEGTWPHTRDWLRRSF--WDI
MMAR_4821|M.marinum_M GATTTERRELARRYEIGVSNMLWGNDFPHPEGTWPHTREWLRRSF--WDI
MUL_0389|M.ulcerans_Agy99 GASFLRPVECAQRHRIGVDRIMWASDYPHMEGTAPYSREALRHTF--SDV
TH_2827|M.thermoresistible__bu VNPFHEEDLSGLIDLIGADRVLFGSDFPHPEG----LAEPAKLTPEIAEL
** ..: : *:** :. : ::
Mflv_2441|M.gilvum_PYR-GCK PDDEINKMTYENAMRWYHWDPFTHIAKEQATVGALRKAAEGHDVSIQALS
Mvan_2022|M.vanbaalenii_PYR-1 PDDEIDKMTYQNAMRWYHWDPFTHIPKEQATVGALRKAAEGHDVSIQALS
MSMEG_4837|M.smegmatis_MC2_155 PDDEINKITHENAMRLYHFDPFAHVPKEQATVGALRKAAEGHDVSIRALS
MAV_3540|M.avium_104 PVEETRQMLGLAAAELYNFDLGALAPLAARIGPVPADLGQDDAVSIPKWE
MMAR_4821|M.marinum_M PIDETRQILGLAAAEVYNFDLDALAPLAGRIGPTPADLGQDDAVSVPKWE
MUL_0389|M.ulcerans_Agy99 DPDEVAAMVGGNAAAVYGFDLQALAPLAARIGPTVTEVAEP-LAAIPADA
TH_2827|M.thermoresistible__bu PEPTIEAVMGGNLRELLTAVPHGR--------------------------
:
Mflv_2441|M.gilvum_PYR-GCK NK---EKTG--TTFSDFAASAKSISGNKD
Mvan_2022|M.vanbaalenii_PYR-1 HHKEGERGGGAGHFDALNAAARGNSGAD-
MSMEG_4837|M.smegmatis_MC2_155 KK---DKTG--ASFADFQANAKAVSGARD
MAV_3540|M.avium_104 AARRTGRHW----LTDAEPMPDLVQS---
MMAR_4821|M.marinum_M AARQAGRHW----LTGAEPLADLVQN---
MUL_0389|M.ulcerans_Agy99 SS------------TAFEPDPIRAW----
TH_2827|M.thermoresistible__bu -----------------------------