For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MNRDDMILISVDDHIVEPPDMFKNHLSKKYLVEAPRLVHNEDGSDTWQFRDVVIPNVALNAVAGRPKEEY GLEPQGLDEIRPGCWQVDERVKDMNAGGILGSMCFPSFPGFAGRLFATEDPEFSLALVQAYNDWHVEEWC GAYPARFIPMTLPVIWDPEACAKEIRRNAARGVHSLTFSENPSAMGYPSFHDFDHWKPMWDALVDTDTVL NVHIGSSGRLAITAPDAPMDVMITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEGGTGWIPYFLERVDR TYEMHSTWTGQDFKGKLPSEVFREHFLTCFIADPVGVATRHQIGVDNICWEADYPHSDSMWPGAPEQLDE VLKANNVPDDEINKMTYENAMRWYHWDPFTHIAKEQATVGALRKAAEGHDVSIQALSHHKEGERGGGAGH FDALNAAARGNSGA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4324 | - | - | 100% (434) | amidohydrolase 2 |
| M. gilvum PYR-GCK | Mflv_2441 | - | 0.0 | 98.05% (411) | amidohydrolase 2 |
| M. gilvum PYR-GCK | Mflv_2371 | - | e-115 | 47.77% (404) | amidohydrolase 2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4742 | - | 0.0 | 80.28% (431) | metal-dependent amidohydrolase |
| M. avium 104 | MAV_0907 | - | 0.0 | 81.21% (431) | amidohydrolase 2 |
| M. smegmatis MC2 155 | MSMEG_4837 | - | 0.0 | 77.21% (430) | amidohydrolase 2 |
| M. thermoresistible (build 8) | TH_2339 | - | 1e-116 | 48.26% (402) | amidohydrolase 2 |
| M. ulcerans Agy99 | MUL_3143 | - | 9e-92 | 46.11% (373) | amidohydrolase |
| M. vanbaalenii PYR-1 | Mvan_2022 | - | 0.0 | 97.24% (434) | amidohydrolase 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4324|M.gilvum_PYR-GCK -----MNRDDMILISVDDHIVEPPDMFKNHLSKKYLVEAPRLVHNEDGSD
Mvan_2022|M.vanbaalenii_PYR-1 -----MNRDDMILISVDDHIVEPPDMFKNHLPSKYLDEAPRLVHNPDGSD
MMAR_4742|M.marinum_M -----MNKEDMILISVDDHTVEPPNMFKNHLSAKYLDDAPRLVHNPDGSD
MAV_0907|M.avium_104 -----MNKEDMILISVDDHTVEPPDMFKNHLPKKYLDDAPRLVHNPDGSD
MSMEG_4837|M.smegmatis_MC2_155 -----MNKDDMILISVDDHIIEPPDMFKNHLPAKYRDEAPRLVHNPDGSD
TH_2339|M.thermoresistible__bu -MSHDLRPEDLILVSIDDHVVEPPDMFLRHVPAKYRDEAPIVVTDENGVD
MUL_3143|M.ulcerans_Agy99 MTDPPRARRRYTVISVDDHIVEPPDTFTGRLPQRFADRAPRVVETDDGGQ
::*:*** :***: * ::. :: ** :* :* :
Mflv_4324|M.gilvum_PYR-GCK TWQFRDVVIPNVALNAVAGRPKEEYGLEPQGLDEIRPGCWQVDERVKDMN
Mvan_2022|M.vanbaalenii_PYR-1 TWQFRDVVIPNVALNAVAGRPKEEYGLEPQGLDEIRPGCWQVDERVKDMN
MMAR_4742|M.marinum_M MWKFRDTVIPNVALNAVAGRPKEEYGLEPQGLDEIRPGCYNVDERIKDMN
MAV_0907|M.avium_104 MWKFRDTVIPNVALNAVAGRPKEEYGIEPTGLDEIRPGCYNVDERVKDMN
MSMEG_4837|M.smegmatis_MC2_155 TWQFRDTVIPNVALNAVAGRPKEEYGLEPQGLDEIRKGCYDPNERVKDMN
TH_2339|M.thermoresistible__bu QWMYQGRPQGVSGLNAVVSWPPEEWGRNPARFAEMRPGVYDVHERVRDMN
MUL_3143|M.ulcerans_Agy99 VWVYDGQVLPNVGFNAVVGRPVSEYGFEPVRFDEMRRGAWDIHERIKDMD
* : . .:***.. * .*:* :* : *:* * :: .**::**:
Mflv_4324|M.gilvum_PYR-GCK AGGILGSMCFPSFP-GFAGR--LFATEDPEFSLALVQAYNDWHVEEWCGA
Mvan_2022|M.vanbaalenii_PYR-1 AGGILGSMCFPSFP-GFAGR--LFATEDAEFSLALVQAYNDWHVEEWCGA
MMAR_4742|M.marinum_M AGGILASICFPSFP-GFAGR--LFATEDPDFSVALVQAYNDWHIDEWCGA
MAV_0907|M.avium_104 AGGILASICFPSFP-GFAGR--LFATEDNDFSIALVQAYNDWHIDEWCGA
MSMEG_4837|M.smegmatis_MC2_155 AGGVLATMNFPSFP-GFAAR--LFATDDEEFSLALVQAYNDWHIDEWCAS
TH_2339|M.thermoresistible__bu RNGILASMCFPTFT-GFSAR--HLNMHREHVTLIMVSAYNDWHIDEWAGS
MUL_3143|M.ulcerans_Agy99 LNGVYASLNFPSFLPGFAGQRLQQVTKDPELAWAAVRAWNDWHLEAWAGP
.*: .:: **:* **:.: . ..: * *:****:: *...
Mflv_4324|M.gilvum_PYR-GCK YPARFIPMTLPVIWDPEACAKEIRRNAARGVHSLTFSENPSAMGYPSFHD
Mvan_2022|M.vanbaalenii_PYR-1 YPARFIPMTLPVIWDPVACAAEIRRNAARGVHSLTFSENPSAMGYPSFHD
MMAR_4742|M.marinum_M YPARFVPMAIPVIWDAEACAAEVRRVAKKGVHALTFTENPAAMGYPSFHN
MAV_0907|M.avium_104 YPARFIPMAIPVIWDAEECAKEVRRVSKKGVHALTFTENPAAMGYPSFHD
MSMEG_4837|M.smegmatis_MC2_155 NPGRFIPMAIPAIWNPGLAAAEVRRVAEKGVHSLTFTENPSTLGYPSFHD
TH_2339|M.thermoresistible__bu YPGRFIPIAILPTWNPEAMCAEIRRVAAKGCRAVTMPELPHLEGLPSYHD
MUL_3143|M.ulcerans_Agy99 YPERIIPCQLPWLLDPSAGAQLIHENAERGFRAVSFSENPAMLGLPSIHS
* *::* : :. . ::. : :* :::::.* * * ** *.
Mflv_4324|M.gilvum_PYR-GCK FDHWKPMWDALVDTDTVLNVHIGSSGRLAITAPDAPMDVMITLQPMNIVQ
Mvan_2022|M.vanbaalenii_PYR-1 FEHWKPMWDALVDTDTVLNVHIGSSGRLAITAPDAPMDVMITLQPMNIVQ
MMAR_4742|M.marinum_M -EYWNPLWKALCDTNTVMNIHIGSSGRLAITAPDAPMDVMITLQPMNIVQ
MAV_0907|M.avium_104 -EYWNPLWKALVDTNTVMNVHIGSSGRLAITAPDAPMDVMITLQPMNIVQ
MSMEG_4837|M.smegmatis_MC2_155 LEYWRPLWQALVDTETVMNVHIGSSGKLAITAPDAPMDVMITLQPMNIVQ
TH_2339|M.thermoresistible__bu EDYWGPVFRTLSEENVVMCLHIGTGFGAISMAPDAPIDNMIILATQVSAM
MUL_3143|M.ulcerans_Agy99 -GHWDPMMAACAETGTVVNLHIGSSGSSPSTTDDAPADVPGVLFFAYAIS
:* *: : : .*: :***:. : *** * *
Mflv_4324|M.gilvum_PYR-GCK AAADLLWSRPIKEYPDLKIALSEGGTGWIPYFLERVDRTYEMHSTWTG-Q
Mvan_2022|M.vanbaalenii_PYR-1 AAADLLWSRPIKEYPDLKIALSEGGTGWIPYFLERVDRTYEMHSTWTG-Q
MMAR_4742|M.marinum_M AAADLLWSRPIKEYPDLKIALSEGGTGWIPYFLERADRTFEMHSTWTH-Q
MAV_0907|M.avium_104 AAADLLWSRPIKEFPDLKIALSEGGTGWIPYFLERADRTFEMHSAWTH-Q
MSMEG_4837|M.smegmatis_MC2_155 AAADLLWSAPIKEFPTLKIALSEGGTGWIPYFLDRVDRTFEMHSTWTH-Q
TH_2339|M.thermoresistible__bu CAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLDRCDRHYTN-QKWLR-R
MUL_3143|M.ulcerans_Agy99 AAVDWLYSGLPSRFPDLKICLSEGRIGWVAGLLDRLDHMLSYHEMYGTWR
.* * *:. .:* **:.:*** **:. *:* *: . : :
Mflv_4324|M.gilvum_PYR-GCK DFKGKLP-SEVFREHFLTCFIADPVGVATRHQIGVDNICWEADYPHSDSM
Mvan_2022|M.vanbaalenii_PYR-1 DFKGKLP-SEVFREHFLTCFIADPVGVATRHQIGVDNICWEADYPHSDSM
MMAR_4742|M.marinum_M NFGGKIP-SEVFREHFLTCFISDKVGVALRNMIGIDNIAWEADYPHSDSM
MAV_0907|M.avium_104 DFKGKLP-SEVFREHFLTCFISDKVGVALRNEIGIDNICWEADYPHSDSM
MSMEG_4837|M.smegmatis_MC2_155 NFGGKLP-SEVFREHFMTCFISDPVGVKNRHMIGIDNICWEMDYPHSDSM
TH_2339|M.thermoresistible__bu DFGDKLP-SDVFREHSLACYVTDKTSLKLRHEIGIDIIAWECDYPHSDCF
MUL_3143|M.ulcerans_Agy99 AMGESLTSAEVFTRNFWFCAVEDKSSFVQHYRIGTENIMVESDYPHCDST
: .:. ::** .: * : * .. : ** : * * ****.*.
Mflv_4324|M.gilvum_PYR-GCK WPGAPEQLDEVLKANNVPDDEINKMTYENAMRWYHWDPFTHIAKEQATVG
Mvan_2022|M.vanbaalenii_PYR-1 WPGAPEQLDEVLKVNNVPDDEIDKMTYQNAMRWYHWDPFTHIPKEQATVG
MMAR_4742|M.marinum_M WPGAPEELWDVLSVNDVPDGEINKMTYENAMRWYSFDPFSHITREQATVG
MAV_0907|M.avium_104 WPGAPEELWDVLSINNVPDDEINKMTYQNAMRWYSFDPFTHISREQATVG
MSMEG_4837|M.smegmatis_MC2_155 WPGAPEELSAVFDTYDVPDDEINKITHENAMRLYHFDPFAHVPKEQATVG
TH_2339|M.thermoresistible__bu WPDAPEQVHAELRAAGADDFDINKITWENSCRFFSWDPFEHTPRAEATVG
MUL_3143|M.ulcerans_Agy99 WPHTQQTMHEQLDG--LPADVIRKITWENAARLYQHPVPVAIAQNPEAF-
** : : : : * *:* :*: * : .: :.
Mflv_4324|M.gilvum_PYR-GCK ALRKAAEGHDVSIQALSHHKEGERGGGAGHFDALNAAARGNSGA-
Mvan_2022|M.vanbaalenii_PYR-1 ALRKAAEGHDVSIQALSHHKEGERGGGAGHFDALNAAARGNSGAD
MMAR_4742|M.marinum_M ALRKAAEGHDVSVRALSHHKDARSGSSVAEFTANAKALTGNKD--
MAV_0907|M.avium_104 ALRKAAEGHDVSIKAQGHDKDSRGGSSFAEFAANAKALTGNKD--
MSMEG_4837|M.smegmatis_MC2_155 ALRKAAEGHDVSIRALS--KKDKTGASFADFQANAKAVSGARD--
TH_2339|M.thermoresistible__bu ALRAKATDVDTTIRSRA-----EWAQLYEQKQQFAQA--------
MUL_3143|M.ulcerans_Agy99 ---------------------------------------------