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M. thermoresistible (build 8) TH_2827 (-)

annotation: amidohydrolase 2
coordinates: 3456671 - 3457864
length: 398

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2827--100% (398)amidohydrolase 2
M. thermoresistible (build 8)TH_0554-e-11348.96% (384) amidohydrolase family protein
M. thermoresistible (build 8)TH_0536-e-10650.13% (385) amidohydrolase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_3792-1e-10850.91% (385) amidohydrolase 2
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0299-7e-0725.40% (248) putative amidohydrolase (aminocarboxymuconate-semialdehyde
M. marinum MMMAR_3988-1e-10547.66% (384) metal-dependent hydrolase
M. avium 104MAV_1625-1e-10346.88% (384) amidohydrolase family protein
M. smegmatis MC2 155MSMEG_2994-1e-10749.87% (385) amidohydrolase family protein
M. ulcerans Agy99MUL_0308-1e-10348.19% (386) hypothetical protein MUL_0308
M. vanbaalenii PYR-1Mvan_2602-1e-10850.65% (385) amidohydrolase 2

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_2994|M.smegmatis_MC2_155      MPSRILDFPVFDADNHFYEPKEALTKFLPDHRKGVIDYVDIRGRTKIVVR
Mvan_2602|M.vanbaalenii_PYR-1       MPSRILDYPVFDADNHFYEPKEALTKFLPDKRKGVIDYIDVHGRTKIMVR
Mflv_3792|M.gilvum_PYR-GCK          MPSRSLDYPVFDADNHFYEPKEALTQFLPDHRKGVIDYIDVHGRTKIVVR
MMAR_3988|M.marinum_M               MPSRELPFPVFDADNHMYEPQEALTKFLPDKRRHVIDYVQVRGRTKIVVR
MAV_1625|M.avium_104                MPSRELSFPVFDADNHMYEPQEALTKFLPDHRKHVIDYVQIRGRTKIVVR
MUL_0308|M.ulcerans_Agy99           MSSAALSYPLFDADNHLYETEESLTKYLPKQYRGVIQYVQVNGRTKIAIR
TH_2827|M.thermoresistible__bu      --VTAPALEIWDADNHLYEPTDAYTRHLPKQYRGAIQWIQVDGLTKLMIK
MAB_0299|M.abscessus_ATCC_1997      -----MTSVRIDIHAHLWS-------------------------------
                                               * . *::.                               

MSMEG_2994|M.smegmatis_MC2_155      NHISDYIPNPTFEVVARPGAQEEYFRQGS-GGKSYREVLGKPMKSIPAFR
Mvan_2602|M.vanbaalenii_PYR-1       NHISDYIPNPTFEVVARPGAQEEYFRHGS-GGKSFREVMGKPMKAIPAFR
Mflv_3792|M.gilvum_PYR-GCK          NHISDYIPNPTFEVVARPGAQEEYFKHGS-GGKSFREVMGKPMKAIPAFR
MMAR_3988|M.marinum_M               GQISDYIPNPTFEVVARPGAQEEYFRNGS-RGKSYREVMGEPMKAIPAFR
MAV_1625|M.avium_104                GHISEYIPNPTFEVVARPGAQEEYFRNGS-GGKSYREILGEPMKAIPAFR
MUL_0308|M.ulcerans_Agy99           GQISDYIPNPTFEVVARPGAMEEYFRIGNPDGKSRREIFGEPMRSIPAFR
TH_2827|M.thermoresistible__bu      GRLTDTIPNPTYEVVASPGAWADYFRGINPEGKSLRELA-NPIRCPEEFR
MAB_0299|M.abscessus_ATCC_1997      --------DEYLSLLDGYGRPATDVHRGLGAGATRDDLDG----------
                                            :   .::   *     .:     * :  ::            

MSMEG_2994|M.smegmatis_MC2_155      NPEARLEVMDGLGLDYTLMFPTLASLVEERLKDDPELIHDIIHALNEWMY
Mvan_2602|M.vanbaalenii_PYR-1       NPEARLEVMDGLGLDYTLMFPTLASLVEERLKDDPELIHDIIHALNEWMY
Mflv_3792|M.gilvum_PYR-GCK          NPEARLEVLDGLGLDYTIMFPTLASLVEERMKDDPDLILDIVHALNQWMY
MMAR_3988|M.marinum_M               EPGPRLEVMDELGLDYALMFPTLASLVEERMKDDPEMTHDVIHALNQWMY
MAV_1625|M.avium_104                EPGARLEVMDELGIDYALMFPTLASLVEERMKDDPEMTHDVIHALNQWMY
MUL_0308|M.ulcerans_Agy99           EPGPRLELMNELGVDRSLMFPTLASLIEERMRDDPLLIHIVVHALNEWLH
TH_2827|M.thermoresistible__bu      HAEQRLRLLDAQGIQACVMFPTTGGMLEERMLDDIELTHAVVHAYNEWLL
MAB_0299|M.abscessus_ATCC_1997      ----RFELMDEAGVDLQILTATPASPHFEDQAAAVASARFINDEY-----
                                        *:.:::  *::  :: .* ..   *           : .       

MSMEG_2994|M.smegmatis_MC2_155      ETWQFDYEGRIFSTPVITLPIVDRALEELEWCLERGAKTVLVRPAPVPGF
Mvan_2602|M.vanbaalenii_PYR-1       ETWQFDYEGRIFSTPVITLPIVDRALEELEWCLERGAKTVLVRPAPVPGF
Mflv_3792|M.gilvum_PYR-GCK          ETWQFDYQGRILSTPVINLSVVDRALEELQWCLERGARTVLVRPAPVPGY
MMAR_3988|M.marinum_M               ETWSFNYKDRIFATPVITLPIVDRALEELEWCLQRGARTVLVRPAPVPGY
MAV_1625|M.avium_104                EQWSFNYKDRIFATPVITLPIVDRALEELEWCLERGARTVLVRPAPVPGY
MUL_0308|M.ulcerans_Agy99           EEWGFRYQDRIFTVPVVSLPIVEKAIEELDWVVERGARAVLVRPAPVPGY
TH_2827|M.thermoresistible__bu      EEWTFDYAGRIFATPVITLPDVDKAVAELNWCVENGARAVLVNPRPVATI
MAB_0299|M.abscessus_ATCC_1997      AKLSSEYPGRFGALASLPLPHVPAALEELARAIDELG---MYGASITTSV
                                          * .*: : . : *. *  *: **   ::. .   :  .  ..  

MSMEG_2994|M.smegmatis_MC2_155      RG-TRSFGTEEFDPFWQACVKAGIPVAMHASDSGYAQYLNDWEPAD-EFL
Mvan_2602|M.vanbaalenii_PYR-1       RG-TRSFGTEEFDPFWDACVKAGIPVAMHASDSGYAQYLNDWEPAD-EFL
Mflv_3792|M.gilvum_PYR-GCK          RG-SRSLGLPEFDPFWDACVQAGIPVCMHASDSGYAQYLNDWEPAD-EFL
MMAR_3988|M.marinum_M               RG-SRSFGFEEFDPFWQACIKAGIPVSMHASDSGYSEFLNVWEPGD-EFL
MAV_1625|M.avium_104                RG-SRSFGFEEFDPFWQACVRAEIPVSMHASDSGYSELLNIWEPGD-EFL
MUL_0308|M.ulcerans_Agy99           RG-PRSFALPEFDPFWHRCVEHDVLVAMHSSASGYARYTAEWDGGDKEML
TH_2827|M.thermoresistible__bu      TGHTTSMGQPYFDPFWHRVEQLGIPVLMHACDSGYDRYSRDWEGKGGEYT
MAB_0299|M.abscessus_ATCC_1997      LG--RSIADPIFDPLYAELNRRRAVLFVHPAGCG----------AESSLI
                                     *   *:.   ***::    .    : :*.. .*             .  

MSMEG_2994|M.smegmatis_MC2_155      PFKPTAFR-MVAMGKRPIEDTMTALVCHGTFTRNPDLRILSIENGASWVP
Mvan_2602|M.vanbaalenii_PYR-1       PFRPTAFR-MVAMGKRPIEDTMAALVCHGAFTRNPDLRILSIENGASWVP
Mflv_3792|M.gilvum_PYR-GCK          PFRPTAFR-MVAMGKRPIEDTMAALVCHGALTRNPDLRILSIENGASWVP
MMAR_3988|M.marinum_M               PFKPTAFR-MLAMGKRPIEDAMGALVCHGALSRNPELRILSIENGADWVP
MAV_1625|M.avium_104                PFKPTAFR-SLAMGHRPVEDAFGALICHGALSRNPDLRILSIENGADWVP
MUL_0308|M.ulcerans_Agy99           PFQTNAFS-MLNEWR-PVQDAVASWVIHGALYRVPRLKVAVIEAGSKWLF
TH_2827|M.thermoresistible__bu      PFKPDAFRTIVYEDARSILDTCAALVAHGVFTRHPGVRVGVVENGGAWVP
MAB_0299|M.abscessus_ATCC_1997      TDHSLTWS---IGAPIEDTVAIMHLIVAGVPSRYPDMKIVTCHLGGALPM
                                    . :. ::             :    :  *.  * * :::   . *.    

MSMEG_2994|M.smegmatis_MC2_155      HLFHQFEDVYAKMPQDFPE-EPIQAFKRCVYVAPFWEDN--FKQMADLIG
Mvan_2602|M.vanbaalenii_PYR-1       YLFYQFKDVYSKMPQEFPE-DPIEAFRRCVYVAPFWEDD--FKKMADLCG
Mflv_3792|M.gilvum_PYR-GCK          YLFYQFEDVYKKMPQEFPE-NPIDAFRRGVYVAPFWEDD--FGKMADLLG
MMAR_3988|M.marinum_M               TLFKGLKGVYKKMPNAFME-DPIEAFKRCVYISPFWEDR--FAEIVKMVG
MAV_1625|M.avium_104                HLFKGLKGVYKKMPQAFAE-DPIETFKRCVYVSPFWEDR--FAEIVNMVG
MUL_0308|M.ulcerans_Agy99           PLLDQLADVYKKTPESFPGGDPVEEIKNRIHISPFYEDG--IADLIKLIG
TH_2827|M.thermoresistible__bu      RLIDLFERVYKKMPNEFGA-HPVEQFREHVWVNPFHEED--LSGLIDLIG
MAB_0299|M.abscessus_ATCC_1997      VLERAHRQVTEWEATQCPE-APRDAARRLWYDTVGHDHTPALRAAVASLG
                                     *      *    .       * :  :.        :.   :       *

MSMEG_2994|M.smegmatis_MC2_155      IDRVIFGSDWPHPEGLADPINLVSDLQAHGLDDEGVRKVMGRNLVDLFQV
Mvan_2602|M.vanbaalenii_PYR-1       IDRVIFGSDWPHPEGLADPINLVADLEAHGLDQEGVRKVMGKNMVDLFRV
Mflv_3792|M.gilvum_PYR-GCK          IDRVIFGSDWPHPEGLADPITLVDQLEENGLDEDGIRKVMGGNLVDLFKV
MMAR_3988|M.marinum_M               TDRVVFGSDWPHPEGLKDPISFVDELAG--FPPEDVAKIMGGNMMEVMKI
MAV_1625|M.avium_104                TDRVVFGSDWPHPEGLKDPISFVDELAD--FSDEDKAKIMGGNLMKLMKV
MUL_0308|M.ulcerans_Agy99           TDRVLYGSDYPHPEGLAQPRHYADALQD--LSVDDQAKIMGGNLARLMSV
TH_2827|M.thermoresistible__bu      ADRVLFGSDFPHPEGLAEPAKLTPEIAE--LPEPTIEAVMGGNLRELLTA
MAB_0299|M.abscessus_ATCC_1997      VDRLIFGSDFPYQAGPRYVSSATYIEEG--LSAEDASAILDHNGAELLGL
                                     **:::***:*:  *       .       :       ::. *   ::  

MSMEG_2994|M.smegmatis_MC2_155      ENKVVYKPDVPALVIA
Mvan_2602|M.vanbaalenii_PYR-1       ENKVVYKPDVPALVIA
Mflv_3792|M.gilvum_PYR-GCK          PNKVVHKPDAPALVIA
MMAR_3988|M.marinum_M               GTPAP-QPVNA-----
MAV_1625|M.avium_104                SAPAAKKPVSA-----
MUL_0308|M.ulcerans_Agy99           ----------------
TH_2827|M.thermoresistible__bu      VPHGR-----------
MAB_0299|M.abscessus_ATCC_1997      TGV-------------