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LLDPWAIAVLATALSAAWACRPSLWFDEGATISAAASRTLPELWRLLGHIDAVHGAYYLLMHGWFALFPP TEFFSRLPSALAVGAAAAGVTVFTRQFAPRRTAVCAGAVFALLPRMTWAGMEARPYAFVAAAAVWLTVLF VAAVRRGAPRGWVGYALALMLAILLNLNMVLMVPVYGVMLPLLTARGARRSAALWWAGSSAVAVGAMTPF LLFAHNQVWQVNWIYPVSWHYAFDIILRQYFDHSVALAVLSAVLIVAAAVARLAGVPAPPGDLRRLLILC AAWMVIPTALVVVYSAVAEPIYYPRYLIFTAPAMAIVLAVCIVTLARRPWPIAGAVLLCAVAALPNYLFV QRWPYAKEGWDYSQVADLIGSHAAPGDCLLVDNTVPWRPGPIRALLATRPAAFRSLIDVERGAYGPKVGT LWDGHVAIWLTTAKINKCSTIWTITNKDNSLPDHQSGQSLPPGSAFGQAPAYRFPGYLGFHIVERWQFHY SQVVKSTR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3138 | - | - | 100% (498) | hypothetical protein MAV_3138 |
| M. avium 104 | MAV_4843 | - | e-138 | 50.10% (499) | hypothetical protein MAV_4843 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1661c | - | 0.0 | 70.28% (498) | hypothetical protein Mb1661c |
| M. gilvum PYR-GCK | Mflv_0468 | - | 2e-90 | 38.83% (528) | hypothetical protein Mflv_0468 |
| M. tuberculosis H37Rv | Rv1635c | - | 0.0 | 70.28% (498) | transmembrane protein |
| M. leprae Br4923 | MLBr_01389 | - | 0.0 | 72.29% (498) | hypothetical protein MLBr_01389 |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2439 | - | 0.0 | 71.43% (497) | transmembrane protein |
| M. smegmatis MC2 155 | MSMEG_2188 | - | 3e-06 | 28.47% (281) | integral membrane protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1618 | - | 0.0 | 71.63% (497) | transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_4427 | - | 2e-06 | 25.65% (308) | glycosyl transferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1661c|M.bovis_AF2122/97 -----------MHASRPGAPPHAG----LPSRRTAGDQDHRADPKVTRIM
Rv1635c|M.tuberculosis_H37Rv -----------MHASRPGAPPHAG----LPSRRTAGDQDHRADPKVTRIM
MMAR_2439|M.marinum_M MEFQAAQHFSRLWAAQPGGPPKPRGQRPPNPRKMTRDQDHRWALTVTSIM
MUL_1618|M.ulcerans_Agy99 -------------------------------------------------M
MLBr_01389|M.leprae_Br4923 ---------------------------------------------MTSIM
MAV_3138|M.avium_104 --------------------------------------------------
Mflv_0468|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2188|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4427|M.vanbaalenii_PYR-1 -----------------------------------------------MTL
Mb1661c|M.bovis_AF2122/97 SASTLEQPAAAH-VDELVARMRGRLLDPLAIAVLAAVISGAWASRPSLWF
Rv1635c|M.tuberculosis_H37Rv SASTLEQPAAAH-VDELVARMRGRLLDPLAIAVLAAVISGAWASRPSLWF
MMAR_2439|M.marinum_M STPTLEQGATAT-DKAERVRPRGRRLDPWLMALLATLISVAWAGKPSLWF
MUL_1618|M.ulcerans_Agy99 STPTLEQGATAT-DKAERVRPRGRRLDPWLMALLATLISVAWAGRPSLWF
MLBr_01389|M.leprae_Br4923 SVSALEQSAADVGDNSARQHAHGALPDSLAIAMLATVISGAWASRPSLWF
MAV_3138|M.avium_104 ------------------------MLDPWAIAVLATALSAAWACRPSLWF
Mflv_0468|M.gilvum_PYR-GCK ---MLRGDGPGP--------ARQWSADAVVVGVLAFALGVAAAGRPSLWV
MSMEG_2188|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4427|M.vanbaalenii_PYR-1 LTPAEKTQTRTQQRHGTRFHVFSRQVMALGGLLVATGVLYLWNLGASGWA
Mb1661c|M.bovis_AF2122/97 DEGATISASASRTLPELWSLLGHIDAVHGLYY-------LLMHGWFAIFP
Rv1635c|M.tuberculosis_H37Rv DEGATISASASRTLPELWSLLGHIDAVHGLYY-------LLMHGWFAIFP
MMAR_2439|M.marinum_M DEGATISAAANRTLPELWKLLGHIDAVHGFYY-------LLMHGWYAIFP
MUL_1618|M.ulcerans_Agy99 DEGATISAAANRTLPELWKLLGHIDAVHGFYY-------LLMHGWYAIFP
MLBr_01389|M.leprae_Br4923 DEAATISASASRTVPELWRLLSHIDAVHGLYY-------LLMHGWFAIFP
MAV_3138|M.avium_104 DEGATISAAASRTLPELWRLLGHIDAVHGAYY-------LLMHGWFALFP
Mflv_0468|M.gilvum_PYR-GCK DEAGTLSAAT-RPVDALWTLVHHVDAVHGFYY-------LLLRGWFEIVP
MSMEG_2188|M.smegmatis_MC2_155 ------------------MLFGAMSVIWGIPY-------LLIK-------
Mvan_4427|M.vanbaalenii_PYR-1 N-AYYSAAVQAGSQNWTAMLFGSSDAANAITVDKPPAALWVMDLSARLFG
*. .. . ::
Mb1661c|M.bovis_AF2122/97 PTELWSRLPSCLAIGAAAAGVVVFAKQFSGRTTAVCAGAVFAILPRVTWA
Rv1635c|M.tuberculosis_H37Rv PTELWSRLPSCLAIGAAAAGVVVFAKQFSGRTTAVCAGAVFAILPRVTWA
MMAR_2439|M.marinum_M PTEFWSRVPSSLAIGGAAAGVVVFTKQFSGRSTALCAGAVFAILPRVTWA
MUL_1618|M.ulcerans_Agy99 PTEFWSRVPSSLAIGGAAAGVVVFTKQFSGRSTALCAGAVFAILPRVTWA
MLBr_01389|M.leprae_Br4923 STEFWSRVPSCLAIGAAAAGVTVFTRQFATRTTAVYAGIVFAILPRITWA
MAV_3138|M.avium_104 PTEFFSRLPSALAVGAAAAGVTVFTRQFAPRRTAVCAGAVFALLPRMTWA
Mflv_0468|M.gilvum_PYR-GCK VTEFWARVPSALMVGVAAAGTCVLGSRLSGRKVGIAAGVVFAVLPRTTWA
MSMEG_2188|M.smegmatis_MC2_155 -----------VAVEGVSVPVLVLARTAVG---------ALVLLP-----
Mvan_4427|M.vanbaalenii_PYR-1 FNPWSVLVPQALMGVAAVAVLYAAVRRASGPGAGLLAGAVLALTPVAALM
: . . . .:.: *
Mb1661c|M.bovis_AF2122/97 GIEARSSALSVAAAVWLTVLLVAAVRCNTQRRWLLYALVLMLSILVS--I
Rv1635c|M.tuberculosis_H37Rv GIEARSSALSVAAAVWLTVLLVAAVRCNTQRRWLLYALVLMLSILVS--I
MMAR_2439|M.marinum_M GIEARSSALSVAAAVWLTVLLVAAVRRNRPWLWLLYALVLMVSILIN--I
MUL_1618|M.ulcerans_Agy99 GIEARSSALSVAAAVWLTVLLVAAVRRDRPWLWLLYALVLMVSILIN--I
MLBr_01389|M.leprae_Br4923 GIEARSSALSVAAAMWLTVLLVASVQRNRPRLWLCYALTLMLSILLN--L
MAV_3138|M.avium_104 GMEARPYAFVAAAAVWLTVLFVAAVRRGAPRGWVGYALALMLAILLN--L
Mflv_0468|M.gilvum_PYR-GCK AVEARPYALSMACAVWLTVLFVAAVRRGGRRWWLGYGAALVGAVTVN--V
MSMEG_2188|M.smegmatis_MC2_155 -LAMSRAAWAPVLRHWKPVLVFAFFEIIAAWALLTDAERHLTSSMTG--L
Mvan_4427|M.vanbaalenii_PYR-1 FRFNNPDALLVLLLVIAEYCTQRACEKGASRWWLIAAGVAIGFGFLTKML
* . : . : :
Mb1661c|M.bovis_AF2122/97 NLALLVPAYATMVPLLASGKSRKSPVIWWTVVTAAALGAMTPFILFAHGQ
Rv1635c|M.tuberculosis_H37Rv NLALLVPAYATMVPLLASGKSRKSPVIWWTVVTAAALGAMTPFILFAHGQ
MMAR_2439|M.marinum_M NLGLLVPVYGALLPLLAPKKSRKSPGIWWAVTSVVAIGAMTPFVLFAHGQ
MUL_1618|M.ulcerans_Agy99 NLGLLVPVYGALLPLLAPKKSRKSPGIWWAVTSVVAIGAMTPFVLFAHGQ
MLBr_01389|M.leprae_Br4923 TLATLVLVYAVILPWLAPNKFRNSPFIWWAVTSVVALGTITPFILFAHGQ
MAV_3138|M.avium_104 NMVLMVPVYGVMLPLLTARGARRSAALWWAGSSAVAVGAMTPFLLFAHNQ
Mflv_0468|M.gilvum_PYR-GCK MVVLILAGHAAML---AATRPDRRTVRAWLVTVVVASVALIPLFVVLLSQ
MSMEG_2188|M.smegmatis_MC2_155 LIAAAPIIAAVLDRITGGERLGVKRVAGLFVG--LSGVAVLAGPGLAGGH
Mvan_4427|M.vanbaalenii_PYR-1 QALLVLPAFAAAYLLAGHRPVGRRILDALTAAGAAVVSAGWYLLLVELWP
.. : .
Mb1661c|M.bovis_AF2122/97 VWQVGWIAGLNRNIILDVIHRQYFDHS-----------------------
Rv1635c|M.tuberculosis_H37Rv VWQVGWIAGLNRNIILDVIHRQYFDHS-----------------------
MMAR_2439|M.marinum_M VWQVGWISGLNRNLFLDVVHRQYFDHS-----------------------
MUL_1618|M.ulcerans_Agy99 VWQVGWISGLNRNLFLDVVHRQYFDHS-----------------------
MLBr_01389|M.leprae_Br4923 VWQVDWIFRVSWHYVFDITQRQYFDHS-----------------------
MAV_3138|M.avium_104 VWQVNWIYPVSWHYAFDIILRQYFDHS-----------------------
Mflv_0468|M.gilvum_PYR-GCK QAQIAWIWPVGPVTLGQIAGEQYFPSVYSDSVRAVGPDQQQFSAEQLRVA
MSMEG_2188|M.smegmatis_MC2_155 VWPVLEVLLVATCYAIAPLVAARFLGEVP---------------------
Mvan_4427|M.vanbaalenii_PYR-1 KESRPYIGGSQTNSITELTLGYNGIGRLTGNEPGGLGNLNHDVGWGRLFG
:
Mb1661c|M.bovis_AF2122/97 -VPFAILAGLIVAAGIAAHLAGARGP--------GGDTHRLVLVSAAWIV
Rv1635c|M.tuberculosis_H37Rv -VPFAILAGLIVAAGIAAHLAGARGP--------GGDTHRLVLVSAAWIV
MMAR_2439|M.marinum_M -VAFAILAGVLVVAAIAVRLTGIARP--------GEGTRPLLLASIAWVV
MUL_1618|M.ulcerans_Agy99 -VAFAILAGVLVVAAIAVRLTGIARP--------GEGTRPLLLASIAWVV
MLBr_01389|M.leprae_Br4923 -VSFAIATAVIIVPAIATRLAGLRAP--------AGDLRSLVIICTAWIV
MAV_3138|M.avium_104 -VALAVLSAVLIVAAAVARLAGVPAP--------PGDLRRLLILCAAWMV
Mflv_0468|M.gilvum_PYR-GCK MSAWARVAPLIVVIVIVAALAVRARRRHGALIENPSGTRVLVLGAVAWIV
MSMEG_2188|M.smegmatis_MC2_155 -SLPMTAACLTVAALIYTTPAALTWP------DAMPSTRVLAALAALAVV
Mvan_4427|M.vanbaalenii_PYR-1 FGMGADIAWLLPAAVICLAAGFVLTRGR----PRTDRTRASLILWAGWLV
: : . : :*
Mb1661c|M.bovis_AF2122/97 VPTAVVLIYSATVEPIY------------------------YPRYLILTA
Rv1635c|M.tuberculosis_H37Rv VPTAVVLIYSATVEPIY------------------------YPRYLILTA
MMAR_2439|M.marinum_M IPTGIVLLYSAIVEPIY------------------------YPRYLILTA
MUL_1618|M.ulcerans_Agy99 IPTGIVLLYSAIVEPIY------------------------YPRYLILTA
MLBr_01389|M.leprae_Br4923 IPTTLMVGYSAVIEPVY------------------------YPRYLILTA
MAV_3138|M.avium_104 IPTALVVVYSAVAEPIY------------------------YPRYLIFTA
Mflv_0468|M.gilvum_PYR-GCK VPTVVLLGYSVLVRPLY------------------------QPHYLTFTT
MSMEG_2188|M.smegmatis_MC2_155 CTALAFIVFFALIREVG------------------------AARALVFTY
Mvan_4427|M.vanbaalenii_PYR-1 VTALVFSYMNGIVHPYYTVALAPAIGAGIGIGSNLLWQNRRDVRSATAMA
.: . . :
Mb1661c|M.bovis_AF2122/97 PAAAVILAVCVVTIAR------------KPWLIAGVVFLLAAAAFPNYFF
Rv1635c|M.tuberculosis_H37Rv PAAAVILAVCVVTIAR------------KPWLIAGVVFLLAAAAFPNYFF
MMAR_2439|M.marinum_M PAAAVILAVCIVTLAR------------KPWLITGVVVLLAVAAFPNYFF
MUL_1618|M.ulcerans_Agy99 PAAAVILAVCIVTLAR------------KPWLITGVVVLLAVAAFPNYFF
MLBr_01389|M.leprae_Br4923 PAAAIVIAVCIVTVAR------------KPWPIAGVLVLFAVAAFPNYLF
MAV_3138|M.avium_104 PAMAIVLAVCIVTLAR------------RPWPIAGAVLLCAVAALPNYLF
Mflv_0468|M.gilvum_PYR-GCK PALALLIGLCVVTLCRD-----------DTRRLTATLAVLAVAAAPNY-L
MSMEG_2188|M.smegmatis_MC2_155 VNPAVALAAGVIVLGEP----------LTAYNIAGLVLILSGSVLATRKA
Mvan_4427|M.vanbaalenii_PYR-1 GAVLVTTVLAAVLLARHSDWMPWLRAAVAVGGVGATVLLLVVGRLHRRAA
: : : . : . : : .
Mb1661c|M.bovis_AF2122/97 TQRGPYAKEGWDYSQVADVISAHAKPGDCLLVDN-TAGWR------PGPI
Rv1635c|M.tuberculosis_H37Rv TQRGPYAKEGWDYSQVADVISAHAKPGDCLLVDN-TAGWR------PGPI
MMAR_2439|M.marinum_M TQRGPYAKEGWDYSQVADVISAHAAPGDCLLVDN-TVPWK------PGPV
MUL_1618|M.ulcerans_Agy99 TQRGPYAKEGWDYSQVADVISTHAAPGDCLLVDN-TVPWK------PGPV
MLBr_01389|M.leprae_Br4923 TQRGRYAKEGWDYSQVADVISSQAAPGDCLIVDN-TVPWR------PGPI
MAV_3138|M.avium_104 VQRWPYAKEGWDYSQVADLIGSHAAPGDCLLVDN-TVPWR------PGPI
Mflv_0468|M.gilvum_PYR-GCK AQRGPYAKYGSDYSQVAELLARESGPRDCVVVDDRTAPSV------PHAI
MSMEG_2188|M.smegmatis_MC2_155 THGNRERETSAKNQPDSRSQFTLAEPIEAIEPIEPKGPTG------PGAT
Mvan_4427|M.vanbaalenii_PYR-1 RLVAALAVTSCLAGPAAFSVATAASPHSGALPSVGPSRHGGPPGGFPGGG
. : : * . *
Mb1661c|M.bovis_AF2122/97 RALLATRPAAFRSLIDVERGTYGPKVGTLWDGHVAVWLTTAKIDKCPTLW
Rv1635c|M.tuberculosis_H37Rv RALLATRPAAFRSLIDVERGTYGPKVGTLWDGHVAVWLTTAKIDKCPTLW
MMAR_2439|M.marinum_M RALLATRPAAFRSLIDVERGAYGPKVGTLWDGHVAVWLTTEKINKCSTLW
MUL_1618|M.ulcerans_Agy99 RALLATRPAAFRSLIDVERGAYGPKVGTLWDGHVAVWLTTEKINKCSTLW
MLBr_01389|M.leprae_Br4923 RALLAARPAAFRSLIDIERGFYGPTVGTLWDGHVPVWLVTAKINKCSTVW
MAV_3138|M.avium_104 RALLATRPAAFRSLIDVERGAYGPKVGTLWDGHVAIWLTTAKINKCSTIW
Mflv_0468|M.gilvum_PYR-GCK EGARRAHPVAAR-----DLGLAPPERTALFSARDPLGVRADDLRTCAVLW
MSMEG_2188|M.smegmatis_MC2_155 RRTP----------------------------------------------
Mvan_4427|M.vanbaalenii_PYR-1 LLSSPNPHPDLIRLLTTDAGQFTWAAAVVGSNNAAGYQLASGAPVMAVGG
Mb1661c|M.bovis_AF2122/97 TIANRDKSLPDHQVGEMLSPGTGFGRTPVYRFPSYLGFRIVERWQFHYSQ
Rv1635c|M.tuberculosis_H37Rv TIANRDKSLPDHQVGEMLSPGTGFGRTPVYRFPSYLGFRIVERWQFHYSQ
MMAR_2439|M.marinum_M TISNRDNALPDHEVGPALSPGTAFGKTPVYLFPHYLGFHIVERWQFHYSQ
MUL_1618|M.ulcerans_Agy99 TISNRDNALPDHEVGPALSPGTAFGKTPVYLFPHYLGFHIVERWQFHYSQ
MLBr_01389|M.leprae_Br4923 TVSDRDTSLPDHQAGQLLSPGLILGRAPAYQFPSYLGFRIVERWQFHYSQ
MAV_3138|M.avium_104 TITNKDNSLPDHQSGQSLPPGSAFGQAPAYRFPGYLGFHIVERWQFHYSQ
Mflv_0468|M.gilvum_PYR-GCK TIG-------DAAPG---SP----ADAPVDRVARAQGFVPAERWRFNQTE
MSMEG_2188|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4427|M.vanbaalenii_PYR-1 FNGTDPSPTLEQFVADVQAGRIHYFVVGPRLMMGRSGTETTESAAIRDWV
Mb1661c|M.bovis_AF2122/97 VVKSTR----------------------
Rv1635c|M.tuberculosis_H37Rv VVKSTR----------------------
MMAR_2439|M.marinum_M VIKSTR----------------------
MUL_1618|M.ulcerans_Agy99 VIKSTR----------------------
MLBr_01389|M.leprae_Br4923 VIKSTR----------------------
MAV_3138|M.avium_104 VVKSTR----------------------
Mflv_0468|M.gilvum_PYR-GCK VVRSVPAGARS-----------------
MSMEG_2188|M.smegmatis_MC2_155 ----------------------------
Mvan_4427|M.vanbaalenii_PYR-1 EARYLELTVDGTVVYDLTQGAGNLTGGA