For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. ulcerans Agy99 MUL_1618 (-)

annotation: transmembrane protein
coordinates: 1756895 - 1758463
length: 522

STPTLEQGATATDKAERVRPRGRRLDPWLMALLATLISVAWAGRPSLWFDEGATISAAANRTLPELWKLL
GHIDAVHGFYYLLMHGWYAIFPPTEFWSRVPSSLAIGGAAAGVVVFTKQFSGRSTALCAGAVFAILPRVT
WAGIEARSSALSVAAAVWLTVLLVAAVRRDRPWLWLLYALVLMVSILININLGLLVPVYGALLPLLAPKK
SRKSPGIWWAVTSVVAIGAMTPFVLFAHGQVWQVGWISGLNRNLFLDVVHRQYFDHSVAFAILAGVLVVA
AIAVRLTGIARPGEGTRPLLLASIAWVVIPTGIVLLYSAIVEPIYYPRYLILTAPAAAVILAVCIVTLAR
KPWLITGVVVLLAVAAFPNYFFTQRGPYAKEGWDYSQVADVISTHAAPGDCLLVDNTVPWKPGPVRALLA
TRPAAFRSLIDVERGAYGPKVGTLWDGHVAVWLTTEKINKCSTLWTISNRDNALPDHEVGPALSPGTAFG
KTPVYLFPHYLGFHIVERWQFHYSQVIKSTR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_1618--100% (522)transmembrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1661c-0.078.35% (522) hypothetical protein Mb1661c
M. gilvum PYR-GCKMflv_0468-3e-9238.07% (528) hypothetical protein Mflv_0468
M. tuberculosis H37RvRv1635c-0.078.35% (522) transmembrane protein
M. leprae Br4923MLBr_01389-0.070.17% (523) hypothetical protein MLBr_01389
M. abscessus ATCC 19977-----
M. marinum MMMAR_2439-0.099.43% (522) transmembrane protein
M. avium 104MAV_3138-0.071.63% (497) hypothetical protein MAV_3138
M. smegmatis MC2 155MSMEG_0999-3e-0626.67% (255) integral membrane protein
M. thermoresistible (build 8)-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


MUL_1618|M.ulcerans_Agy99           -------------------------------------------------M
MMAR_2439|M.marinum_M               MEFQAAQHFSRLWAAQPGGPPKPRGQRPPNPRKMTRDQDHRWALTVTSIM
Mb1661c|M.bovis_AF2122/97           -----------MHASRPGAPPHAG----LPSRRTAGDQDHRADPKVTRIM
Rv1635c|M.tuberculosis_H37Rv        -----------MHASRPGAPPHAG----LPSRRTAGDQDHRADPKVTRIM
MLBr_01389|M.leprae_Br4923          ---------------------------------------------MTSIM
MAV_3138|M.avium_104                --------------------------------------------------
Mflv_0468|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0999|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MUL_1618|M.ulcerans_Agy99           STPTLEQGATAT-DKAERVRPRGRRLDPWLMALLATLISVAWAGRPSLWF
MMAR_2439|M.marinum_M               STPTLEQGATAT-DKAERVRPRGRRLDPWLMALLATLISVAWAGKPSLWF
Mb1661c|M.bovis_AF2122/97           SASTLEQPAAAH-VDELVARMRGRLLDPLAIAVLAAVISGAWASRPSLWF
Rv1635c|M.tuberculosis_H37Rv        SASTLEQPAAAH-VDELVARMRGRLLDPLAIAVLAAVISGAWASRPSLWF
MLBr_01389|M.leprae_Br4923          SVSALEQSAADVGDNSARQHAHGALPDSLAIAMLATVISGAWASRPSLWF
MAV_3138|M.avium_104                ------------------------MLDPWAIAVLATALSAAWACRPSLWF
Mflv_0468|M.gilvum_PYR-GCK          ---MLRGDGPGP--------ARQWSADAVVVGVLAFALGVAAAGRPSLWV
MSMEG_0999|M.smegmatis_MC2_155      -------------------------MQIGRRELVAVIIAILLVTAAFVVP
                                                              :     ::*  :.   .  . :  

MUL_1618|M.ulcerans_Agy99           DEGATISAAANRTLPELWKLLGHIDAVHGFYYLLMHGWYAIFPPTEFWSR
MMAR_2439|M.marinum_M               DEGATISAAANRTLPELWKLLGHIDAVHGFYYLLMHGWYAIFPPTEFWSR
Mb1661c|M.bovis_AF2122/97           DEGATISASASRTLPELWSLLGHIDAVHGLYYLLMHGWFAIFPPTELWSR
Rv1635c|M.tuberculosis_H37Rv        DEGATISASASRTLPELWSLLGHIDAVHGLYYLLMHGWFAIFPPTELWSR
MLBr_01389|M.leprae_Br4923          DEAATISASASRTVPELWRLLSHIDAVHGLYYLLMHGWFAIFPSTEFWSR
MAV_3138|M.avium_104                DEGATISAAASRTLPELWRLLGHIDAVHGAYYLLMHGWFALFPPTEFFSR
Mflv_0468|M.gilvum_PYR-GCK          DEAGTLSAAT-RPVDALWTLVHHVDAVHGFYYLLLRGWFEIVPVTEFWAR
MSMEG_0999|M.smegmatis_MC2_155      HLDLGIVTPLINSTPAQIYSFADTAPIFGWWNAHVG-----------WGT
                                    .    : :.  ..       . .  .:.* :   :            :. 

MUL_1618|M.ulcerans_Agy99           VPSSLAIGGAAAGVVVFTKQFSGRSTALCAGAVFAILPRVTWAGIEARSS
MMAR_2439|M.marinum_M               VPSSLAIGGAAAGVVVFTKQFSGRSTALCAGAVFAILPRVTWAGIEARSS
Mb1661c|M.bovis_AF2122/97           LPSCLAIGAAAAGVVVFAKQFSGRTTAVCAGAVFAILPRVTWAGIEARSS
Rv1635c|M.tuberculosis_H37Rv        LPSCLAIGAAAAGVVVFAKQFSGRTTAVCAGAVFAILPRVTWAGIEARSS
MLBr_01389|M.leprae_Br4923          VPSCLAIGAAAAGVTVFTRQFATRTTAVYAGIVFAILPRITWAGIEARSS
MAV_3138|M.avium_104                LPSALAVGAAAAGVTVFTRQFAPRRTAVCAGAVFALLPRMTWAGMEARPY
Mflv_0468|M.gilvum_PYR-GCK          VPSALMVGVAAAGTCVLGSRLSGRKVGIAAGVVFAVLPRTTWAAVEARPY
MSMEG_0999|M.smegmatis_MC2_155      VPAVLIG----AATVWWGPAVAQR-------LPWRALPLVAWVTSALWAF
                                    :*: *      *..      .: *         :  **  :*.     . 

MUL_1618|M.ulcerans_Agy99           ALSVAAAVWLTVLLVAAVRRDRPWLWLLYALVLMVSILININLGLLVPVY
MMAR_2439|M.marinum_M               ALSVAAAVWLTVLLVAAVRRNRPWLWLLYALVLMVSILININLGLLVPVY
Mb1661c|M.bovis_AF2122/97           ALSVAAAVWLTVLLVAAVRCNTQRRWLLYALVLMLSILVSINLALLVPAY
Rv1635c|M.tuberculosis_H37Rv        ALSVAAAVWLTVLLVAAVRCNTQRRWLLYALVLMLSILVSINLALLVPAY
MLBr_01389|M.leprae_Br4923          ALSVAAAMWLTVLLVASVQRNRPRLWLCYALTLMLSILLNLTLATLVLVY
MAV_3138|M.avium_104                AFVAAAAVWLTVLFVAAVRRGAPRGWVGYALALMLAILLNLNMVLMVPVY
Mflv_0468|M.gilvum_PYR-GCK          ALSMACAVWLTVLFVAAVRRGGRRWWLGYGAALVGAVTVNVMVVLILAGH
MSMEG_0999|M.smegmatis_MC2_155      SLAMIDG--WQRGFAGRLTARHEYLRQVPSVTDIGEALRTFSSRILDFQP
                                    ::    .      :.. :           . . :     ..    :    

MUL_1618|M.ulcerans_Agy99           GALLPLLAPKKSRKSPGIWWAVTSVVAIGAMTPFVLFAHGQVWQVGWISG
MMAR_2439|M.marinum_M               GALLPLLAPKKSRKSPGIWWAVTSVVAIGAMTPFVLFAHGQVWQVGWISG
Mb1661c|M.bovis_AF2122/97           ATMVPLLASGKSRKSPVIWWTVVTAAALGAMTPFILFAHGQVWQVGWIAG
Rv1635c|M.tuberculosis_H37Rv        ATMVPLLASGKSRKSPVIWWTVVTAAALGAMTPFILFAHGQVWQVGWIAG
MLBr_01389|M.leprae_Br4923          AVILPWLAPNKFRNSPFIWWAVTSVVALGTITPFILFAHGQVWQVDWIFR
MAV_3138|M.avium_104                GVMLPLLTARGARRSAALWWAGSSAVAVGAMTPFLLFAHNQVWQVNWIYP
Mflv_0468|M.gilvum_PYR-GCK          AAML---AATRPDRRTVRAWLVTVVVASVALIPLFVVLLSQQAQIAWIWP
MSMEG_0999|M.smegmatis_MC2_155      DSWITHVSGHPPGALLTFVWLDRIGLGGGAWAGLLCLLVGSSAAAAIVVA
                                       :   :           *      .  :   :. .  ..      :  

MUL_1618|M.ulcerans_Agy99           LNRNLFLDVVHRQYFDHS------------------------VAFAILAG
MMAR_2439|M.marinum_M               LNRNLFLDVVHRQYFDHS------------------------VAFAILAG
Mb1661c|M.bovis_AF2122/97           LNRNIILDVIHRQYFDHS------------------------VPFAILAG
Rv1635c|M.tuberculosis_H37Rv        LNRNIILDVIHRQYFDHS------------------------VPFAILAG
MLBr_01389|M.leprae_Br4923          VSWHYVFDITQRQYFDHS------------------------VSFAIATA
MAV_3138|M.avium_104                VSWHYAFDIILRQYFDHS------------------------VALAVLSA
Mflv_0468|M.gilvum_PYR-GCK          VGPVTLGQIAGEQYFPSVYSDSVRAVGPDQQQFSAEQLRVAMSAWARVAP
MSMEG_0999|M.smegmatis_MC2_155      LR-AVSGEATARLAAPFV--------------------------AVAPTA
                                    :      :   .                                 .  : 

MUL_1618|M.ulcerans_Agy99           VLVVAAIAVRLTGIARP--------GEGTRPLLLASIAWVVIPTGIVLLY
MMAR_2439|M.marinum_M               VLVVAAIAVRLTGIARP--------GEGTRPLLLASIAWVVIPTGIVLLY
Mb1661c|M.bovis_AF2122/97           LIVAAGIAAHLAGARGP--------GGDTHRLVLVSAAWIVVPTAVVLIY
Rv1635c|M.tuberculosis_H37Rv        LIVAAGIAAHLAGARGP--------GGDTHRLVLVSAAWIVVPTAVVLIY
MLBr_01389|M.leprae_Br4923          VIIVPAIATRLAGLRAP--------AGDLRSLVIICTAWIVIPTTLMVGY
MAV_3138|M.avium_104                VLIVAAAVARLAGVPAP--------PGDLRRLLILCAAWMVIPTALVVVY
Mflv_0468|M.gilvum_PYR-GCK          LIVVIVIVAALAVRARRRHGALIENPSGTRVLVLGAVAWIVVPTVVLLGY
MSMEG_0999|M.smegmatis_MC2_155      IWIAVSADGYFAGVAAW----------GLALLALAVRDSVHRRRVALPTA
                                    : :.      ::               .   * :     :      :   

MUL_1618|M.ulcerans_Agy99           SAIVEPIYYPRYLILTAPAAAVILAVCIVTLAR-KPWLITGVVVLLAVAA
MMAR_2439|M.marinum_M               SAIVEPIYYPRYLILTAPAAAVILAVCIVTLAR-KPWLITGVVVLLAVAA
Mb1661c|M.bovis_AF2122/97           SATVEPIYYPRYLILTAPAAAVILAVCVVTIAR-KPWLIAGVVFLLAAAA
Rv1635c|M.tuberculosis_H37Rv        SATVEPIYYPRYLILTAPAAAVILAVCVVTIAR-KPWLIAGVVFLLAAAA
MLBr_01389|M.leprae_Br4923          SAVIEPVYYPRYLILTAPAAAIVIAVCIVTVAR-KPWPIAGVLVLFAVAA
MAV_3138|M.avium_104                SAVAEPIYYPRYLIFTAPAMAIVLAVCIVTLAR-RPWPIAGAVLLCAVAA
Mflv_0468|M.gilvum_PYR-GCK          SVLVRPLYQPHYLTFTTPALALLIGLCVVTLCRDDTRRLTATLAVLAVAA
MSMEG_0999|M.smegmatis_MC2_155      VGSGLLLGWGIFLNYGLALAALIALAVLITAPDWRAALRVAVPAVIAVLA
                                          :    :*    .  *::    ::*     .   ...  : *. *

MUL_1618|M.ulcerans_Agy99           FPNYFFTQRGPYAKEGWDYSQVADVISTHAAPGDCLLVDN-TVPWKPGPV
MMAR_2439|M.marinum_M               FPNYFFTQRGPYAKEGWDYSQVADVISAHAAPGDCLLVDN-TVPWKPGPV
Mb1661c|M.bovis_AF2122/97           FPNYFFTQRGPYAKEGWDYSQVADVISAHAKPGDCLLVDN-TAGWRPGPI
Rv1635c|M.tuberculosis_H37Rv        FPNYFFTQRGPYAKEGWDYSQVADVISAHAKPGDCLLVDN-TAGWRPGPI
MLBr_01389|M.leprae_Br4923          FPNYLFTQRGRYAKEGWDYSQVADVISSQAAPGDCLIVDN-TVPWRPGPI
MAV_3138|M.avium_104                LPNYLFVQRWPYAKEGWDYSQVADLIGSHAAPGDCLLVDN-TVPWRPGPI
Mflv_0468|M.gilvum_PYR-GCK          APNY-LAQRGPYAKYGSDYSQVAELLARESGPRDCVVVDDRTAPSVPHAI
MSMEG_0999|M.smegmatis_MC2_155      VVAVFLVAGFWWFDG---YTLVQERYWQGIANNRPFQYWS--WANLASVV
                                         :.    : .    *: * :           .   .      .  :

MUL_1618|M.ulcerans_Agy99           RALLATRPAAFRSLIDVERGAYGPKVGTLWDGHVAVWLTTEKINKCSTLW
MMAR_2439|M.marinum_M               RALLATRPAAFRSLIDVERGAYGPKVGTLWDGHVAVWLTTEKINKCSTLW
Mb1661c|M.bovis_AF2122/97           RALLATRPAAFRSLIDVERGTYGPKVGTLWDGHVAVWLTTAKIDKCPTLW
Rv1635c|M.tuberculosis_H37Rv        RALLATRPAAFRSLIDVERGTYGPKVGTLWDGHVAVWLTTAKIDKCPTLW
MLBr_01389|M.leprae_Br4923          RALLAARPAAFRSLIDIERGFYGPTVGTLWDGHVPVWLVTAKINKCSTVW
MAV_3138|M.avium_104                RALLATRPAAFRSLIDVERGAYGPKVGTLWDGHVAIWLTTAKINKCSTIW
Mflv_0468|M.gilvum_PYR-GCK          EGARRAHPVAAR-----DLGLAPPERTALFSARDPLGVRADDLRTCAVLW
MSMEG_0999|M.smegmatis_MC2_155      CAIGLGSVAGIGRVFDIKAARRNPGLPMLVIGALLAITFADLSMLSKAET
                                     .      ..       . .   *    *  .       :     . .  

MUL_1618|M.ulcerans_Agy99           TISNRDNALPDHEVGPALSPGTAFGKTPVYLFPHYLGFHIVERWQFHYSQ
MMAR_2439|M.marinum_M               TISNRDNALPDHEVGPALSPGTAFGKTPVYLFPHYLGFHIVERWQFHYSQ
Mb1661c|M.bovis_AF2122/97           TIANRDKSLPDHQVGEMLSPGTGFGRTPVYRFPSYLGFRIVERWQFHYSQ
Rv1635c|M.tuberculosis_H37Rv        TIANRDKSLPDHQVGEMLSPGTGFGRTPVYRFPSYLGFRIVERWQFHYSQ
MLBr_01389|M.leprae_Br4923          TVSDRDTSLPDHQAGQLLSPGLILGRAPAYQFPSYLGFRIVERWQFHYSQ
MAV_3138|M.avium_104                TITNKDNSLPDHQSGQSLPPGSAFGQAPAYRFPGYLGFHIVERWQFHYSQ
Mflv_0468|M.gilvum_PYR-GCK          TIG-------DAAPG---SP----ADAPVDRVARAQGFVPAERWRFNQTE
MSMEG_0999|M.smegmatis_MC2_155      ERIWLPFTVWLTAAGALLPP---------RSHRWWLGLNVAGALALNHLI
                                                  *   .*                *:  .    ::   

MUL_1618|M.ulcerans_Agy99           VIKSTR-----
MMAR_2439|M.marinum_M               VIKSTR-----
Mb1661c|M.bovis_AF2122/97           VVKSTR-----
Rv1635c|M.tuberculosis_H37Rv        VVKSTR-----
MLBr_01389|M.leprae_Br4923          VIKSTR-----
MAV_3138|M.avium_104                VVKSTR-----
Mflv_0468|M.gilvum_PYR-GCK          VVRSVPAGARS
MSMEG_0999|M.smegmatis_MC2_155      LTNW-------
                                    : .