For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TLLTPAEKTQTRTQQRHGTRFHVFSRQVMALGGLLVATGVLYLWNLGASGWANAYYSAAVQAGSQNWTAM LFGSSDAANAITVDKPPAALWVMDLSARLFGFNPWSVLVPQALMGVAAVAVLYAAVRRASGPGAGLLAGA VLALTPVAALMFRFNNPDALLVLLLVIAEYCTQRACEKGASRWWLIAAGVAIGFGFLTKMLQALLVLPAF AAAYLLAGHRPVGRRILDALTAAGAAVVSAGWYLLLVELWPKESRPYIGGSQTNSITELTLGYNGIGRLT GNEPGGLGNLNHDVGWGRLFGFGMGADIAWLLPAAVICLAAGFVLTRGRPRTDRTRASLILWAGWLVVTA LVFSYMNGIVHPYYTVALAPAIGAGIGIGSNLLWQNRRDVRSATAMAGAVLVTTVLAAVLLARHSDWMPW LRAAVAVGGVGATVLLLVVGRLHRRAARLVAALAVTSCLAGPAAFSVATAASPHSGALPSVGPSRHGGPP GGFPGGGLLSSPNPHPDLIRLLTTDAGQFTWAAAVVGSNNAAGYQLASGAPVMAVGGFNGTDPSPTLEQF VADVQAGRIHYFVVGPRLMMGRSGTETTESAAIRDWVEARYLELTVDGTVVYDLTQGAGNLTGGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4427 | - | - | 100% (626) | glycosyl transferase family protein |
| M. vanbaalenii PYR-1 | Mvan_4425 | - | e-163 | 52.72% (607) | glycosyl transferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3821 | - | 3e-05 | 26.56% (256) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_2269 | - | 1e-151 | 49.75% (609) | glycosyl transferase family protein |
| M. tuberculosis H37Rv | Rv3792 | - | 3e-05 | 26.56% (256) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0927 | - | 1e-169 | 50.16% (624) | glycosyltransferase |
| M. marinum M | MMAR_2338 | - | 7e-06 | 26.15% (325) | hypothetical protein MMAR_2338 |
| M. avium 104 | MAV_3138 | - | 2e-06 | 25.65% (308) | hypothetical protein MAV_3138 |
| M. smegmatis MC2 155 | MSMEG_4988 | - | 0.0 | 68.24% (595) | integral membrane protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4427|M.vanbaalenii_PYR-1 MTLLT--PAEKTQTRTQQRHGTRFHVFSR-QVMALGGLLVATGVLYLWNL
MSMEG_4988|M.smegmatis_MC2_155 MTLVARDPARAEVEAPDSRTSESVRPRSRAERVALPLLLAGTALLYLWNL
MAB_0927|M.abscessus_ATCC_1997 MSVLS-----------------TARGRAR-EPLSVTLLLVGTAVAYLINL
Mflv_2269|M.gilvum_PYR-GCK MTTTVR-------TGVRSAPHPEADTRPRWVTPALLALLASTAVLYLWGL
Mb3821|M.bovis_AF2122/97 MPSRRKSPQFGHEMGAFTSARAREVLVALGQLAAAVVVAVGVAVVSLLAI
Rv3792|M.tuberculosis_H37Rv MPSRRKSPQFGHEMGAFTSARAREVLVALGQLAAAVVVAVGVAVVSLLAI
MAV_3138|M.avium_104 ------------------------------MLDPWAIAVLATALSAAWAC
MMAR_2338|M.marinum_M ---------------------MAGTDDHLPKEQIISSVRVRSALLYIAIA
.:
Mvan_4427|M.vanbaalenii_PYR-1 GASGWANAYYSAAVQAGSQNWTAMLFGSSDAANAITVDKPPAALWVMDLS
MSMEG_4988|M.smegmatis_MC2_155 SISGWANPFYSAAAQAGASDWIAMLFGSSDPANAITVDKTPAALWVIDLS
MAB_0927|M.abscessus_ATCC_1997 ASNGWANSFYSAAVQAGSVSWKAGFFGSSDAANSITVDKPPAALWLMELS
Mflv_2269|M.gilvum_PYR-GCK GSSGWANQYYAAAAQAGTQDWKAWLFGSLDAGNAITVDKPPASLWVMALS
Mb3821|M.bovis_AF2122/97 ARVEWPAFPSSNQLHALT---TVGQVGCLAGLVGIGWLWRHGRFRRLARL
Rv3792|M.tuberculosis_H37Rv ARVEWPAFPSSNQLHALT---TVGQVGCLAGLVGIGWLWRHGRFRRLARL
MAV_3138|M.avium_104 RPSLWFDEG--ATISAAASRTLPELWRLLGHIDAVHG----AYYLLMHGW
MMAR_2338|M.marinum_M VGFVLATAVLRGQQISEWNYLNPDEAELLVQARAARHSPVPFSTWITGTT
: .
Mvan_4427|M.vanbaalenii_PYR-1 ARLFGFNPWSVLVPQALMGVAAVAVLYAAVRRASGPGAGLLAGAVLALTP
MSMEG_4988|M.smegmatis_MC2_155 VRLFGLSSWSVLLPQALEGIAAVAVLYAAVRRAAGWHAAVLAGAVLALTP
MAB_0927|M.abscessus_ATCC_1997 VRVFGLSGWSILVPQVLLGVASVGLLYATVRRYFGHRAGLLAGLVLAVTP
Mflv_2269|M.gilvum_PYR-GCK GRVFGFSPFTMLLPQALMGVASVAVLVAAVRRLSGPGAGLIAGAALAVTP
Mb3821|M.bovis_AF2122/97 GGLVLVSAFTVVTLGMPLGATKLYLFGISVDQQFRTEYLTRLTDTAALRD
Rv3792|M.tuberculosis_H37Rv GGLVLVSAFTVVTLGMPLGATKLYLFGISVDQQFRTEYLTRLTDTAALRD
MAV_3138|M.avium_104 FALFPPTEFFSRLPSALAVGAAAAGVTVFTRQFAPRRTAVCAGAVFALLP
MMAR_2338|M.marinum_M GPYWTLFLTGLAVFGAPLTLTFAHFLAAALLGITAAALLVAASRVIGFGP
: . . ..
Mvan_4427|M.vanbaalenii_PYR-1 VAALMFRFNNPDALLVLLLVIAEYCTQRACEKGA----SRWWLIAAGVAI
MSMEG_4988|M.smegmatis_MC2_155 VAALIFRFNNPDALLVLLLVVAAYCVQRGIEKDA----SRWWFVAAGAAV
MAB_0927|M.abscessus_ATCC_1997 VAVLMFRFNNPDALLVFLMIAAVWAMMRAVEDGR----TRWMLLVG-VFV
Mflv_2269|M.gilvum_PYR-GCK VAALMFRYNNPDALLVLLLVVAAYLMVRAIQTGG----TRWVVLVG-VVL
Mb3821|M.bovis_AF2122/97 MTYIGLPPFYPPGWFWIGGRAAALTGTPAWEMFKPWAITSMAIAVAVALV
Rv3792|M.tuberculosis_H37Rv MTYIGLPPFYPPGWFWIGGRAAALTGTPAWEMFKPWAITSMAIAVAVALV
MAV_3138|M.avium_104 RMTWAGMEARPYAFVAAAAVWLTVLFVAAVRRGAP-------------RG
MMAR_2338|M.marinum_M AWVVTALWWFPFAVIFPVGDPLDFGALATEYLPTSLVVTSALVRREQLAA
* . .
Mvan_4427|M.vanbaalenii_PYR-1 GFGFLTKMLQALLVLPAFAAAYLLAGHRPVGRRILDALTAAGAAVVSAGW
MSMEG_4988|M.smegmatis_MC2_155 GFGFLAKMLQAFLVLPAFCAAALLAGDRPLRARIADLAAAGTAMVVSGGW
MAB_0927|M.abscessus_ATCC_1997 GFGFLTKQLQVLLVIPPVAVTYLIAGPAGAGKRLAQLVGSAAAAVVSAGW
Mflv_2269|M.gilvum_PYR-GCK GVAFLTKMLQAFLVVPGLALAFLVAAPVGVWARVGKLAAGGVAMIATAGS
Mb3821|M.bovis_AF2122/97 LWWRMIRFEYALLVTVATAAVMLAYSSPEPYAAMITVLLPPMLVLTWSGL
Rv3792|M.tuberculosis_H37Rv LWWRMIRFEYALLVTVATAAVMLAYSSPEPYAAMITVLLPPMLVLTWSGL
MAV_3138|M.avium_104 WVGYALALMLAILLNLNMVLMVPVYG------VMLPLLTARGARRSAALW
MMAR_2338|M.marinum_M RPWLFAVVGALAGVAVGSKFQVAPLAVAFAAAQMMVLHTHTKRTVVSMVW
: . :
Mvan_4427|M.vanbaalenii_PYR-1 YLLLVELWPKESRPYIGGSQTNSITELTLGYNGIGRLTGNEPG-------
MSMEG_4988|M.smegmatis_MC2_155 YLVLVELWPAASRPYIGGSQNNSIVELALGYNGFGRLTGAEVG-------
MAB_0927|M.abscessus_ATCC_1997 WIAAVELWPPGSRPWIGGSPDNSILELTLGYNGLGRINGNETGSASGPRE
Mflv_2269|M.gilvum_PYR-GCK FLTLVSVWPADARPYIGGSTDNSLLQLALGYNGIQRVMGGQGGPGGPPGG
Mb3821|M.bovis_AF2122/97 GARDRQGWAAVVGAGVFLGFAATWYTLLVAYGAFTVVLMALLLAGSR---
Rv3792|M.tuberculosis_H37Rv GARDRQGWAAVVGAGVFLGFAATWYTLLVAYGAFTVVLMALLLAGSR---
MAV_3138|M.avium_104 WAGSSAVAVGAMTPFLLFAHN-QVWQVNWIYP------------------
MMAR_2338|M.marinum_M WAAGAVLPLAAIVLTIVVSPATNWVLVDQTLS------------------
: . :
Mvan_4427|M.vanbaalenii_PYR-1 ---GLG----------------NLNHDVGWGRLFGFGMGADIAWLLPAAV
MSMEG_4988|M.smegmatis_MC2_155 ---GLG----------------NSNFDVGAGRLFGWQMGADIAWLLPAAL
MAB_0927|M.abscessus_ATCC_1997 GMYGFGG---------------HFGSEPGIGRLFQPALGGQIAWLLPTAL
Mflv_2269|M.gilvum_PYR-GCK ---GLGGPPAGGPGGPGGGANLFFGGEPDIGRLFGASMGAEASWLLPAAL
Mb3821|M.bovis_AF2122/97 ---------------------LQSGIKAAVDPLCRLAVVGAIAAAIGSTT
Rv3792|M.tuberculosis_H37Rv ---------------------LQSGIKAAVDPLCRLAVVGAIAAAIGSTT
MAV_3138|M.avium_104 -----------------------VSWHYAFDIILRQYFDHSVALAVLSAV
MMAR_2338|M.marinum_M ----------------------FLGSYAGGPTAMQKLLHTWDTFTWPAGY
. . : :
Mvan_4427|M.vanbaalenii_PYR-1 ICLAAGFVLTRGRPR-TDRTRASLILWAGWLVVTALVFSYMNGIVHP---
MSMEG_4988|M.smegmatis_MC2_155 VCLVAGLIVTRRAPR-TDRIRAALIIWGGWLVVTAVVFSYMNGIVHP---
MAB_0927|M.abscessus_ATCC_1997 LLAILGIVLLRNNSR-TDARRAVLIVFGLWILTTGIVFSYMQGIFHP---
Mflv_2269|M.gilvum_PYR-GCK IGLVAALWITRRAAR-TDAIRAGLLLWGGWVLVTGVVFSYMDGIIHP---
Mb3821|M.bovis_AF2122/97 WLPYLLRAARDPVSD-TGSAQHYLPADGAALTFPMLQFSLLGAICLLGTL
Rv3792|M.tuberculosis_H37Rv WLPYLLRAARDPVSD-TGSAQHYLPADGAALTFPMLQFSLLGAICLLGTL
MAV_3138|M.avium_104 LIVAAAVARLAGVPAPPGDLRRLLILCAAWMVIPTALVVVYSAVAEP--I
MMAR_2338|M.marinum_M MLVLLAVVIWLGRHSDRRSKLARIVVIGG-----GLVCTLIGGMGFP---
: . .:
Mvan_4427|M.vanbaalenii_PYR-1 ---YYTVALAPAIGAGIGIGSNLLWQNRRDVRSATAMAGAVLVTTVLAAV
MSMEG_4988|M.smegmatis_MC2_155 ---YYTVALAPAIGAVIGIGATSMWRHRNDIRVATAMAAAVAVTVILAAV
MAB_0927|M.abscessus_ATCC_1997 ---YYSMALTPAVAALVGAGSVLGWREREKSWVRACLAALLMLTAAMAWL
Mflv_2269|M.gilvum_PYR-GCK ---YYTVALAPGIAALIGISVVTLWRGRGLFAPRLILAAMSAVTGVWAFV
Mb3821|M.bovis_AF2122/97 WLVMRARSSAPAGALAIGVLAVYLWSLLSMLATLARTTLLSFRLQPTLSV
Rv3792|M.tuberculosis_H37Rv WLVMRARSSAPAGALAIGVLAVYLWSLLSMLATLARTTLLSFRLQPTLSV
MAV_3138|M.avium_104 YYPRYLIFTAPAMAIVLAVCIVTLARRPWPIAGAVLLCAVAALPNYLFVQ
MMAR_2338|M.marinum_M ---HYLILLFGALGLAT---TMPIKPGAQLVPQRLSPALVASAVAVVTVV
. .
Mvan_4427|M.vanbaalenii_PYR-1 LLARHSDWMPWLRAAVAVGGVGATVLLLVVGRLHRRAARLVAALAVTSCL
MSMEG_4988|M.smegmatis_MC2_155 LLARHNDPMPWLRATVAVVGVAVAVLLLVVDLVHTRLVRPLAALTVLICL
MAB_0927|M.abscessus_ATCC_1997 LLGRSPEFQPWLRWAILIL-----ALLALIGLAMSRCPKAVVVAALVAAL
Mflv_2269|M.gilvum_PYR-GCK LLDRTPEWQPWLRWVVLVGSIAVAVVFSAGAHRLGRATVAVAAAAIVLGA
Mb3821|M.bovis_AF2122/97 LLVAAGAFG-FVEAVQALGKRGRGVIPMAAAIGLAGAIAFSQDIPDVLRP
Rv3792|M.tuberculosis_H37Rv LLVAAGAFG-FVEAVQALGKRGRGVIPMAAAIGLAGAIAFSQDIPDVLRP
MAV_3138|M.avium_104 RWPYAKEGWDYSQVADLIGSHAAPGDCLLVDNTVPWRPGPIRALLATRPA
MMAR_2338|M.marinum_M MLVVGYAMDRWRPLSPQQAAAAFSANSVHRNSSMAR-ACPPGSSALVWGW
:
Mvan_4427|M.vanbaalenii_PYR-1 AGPAAFSVATAAS-PHSG-ALPSVGPSRHGGPPGGFP-------------
MSMEG_4988|M.smegmatis_MC2_155 AGPGAYAVATAAA-PHTG-AIPSVGPSR------GF--------------
MAB_0927|M.abscessus_ATCC_1997 AGPVAYSAATIAT-PHGG-ALPSAGPEVNGGGFPEFPDMPERPHRAEFEP
Mflv_2269|M.gilvum_PYR-GCK AAPLAYALETALH-SHAGGAMAMSGPARD----SGFG-------------
Mb3821|M.bovis_AF2122/97 DLTIAYTDTDGYG-QRGD-RRPPGSEKYYPAIDAAIR-------------
Rv3792|M.tuberculosis_H37Rv DLTIAYTDTDGYG-QRGD-RRPPGSEKYYPAIDAAIR-------------
MAV_3138|M.avium_104 AFRSLIDVERGAYGPKVG--------------------------------
MMAR_2338|M.marinum_M APEIFVEQDWQNTVPYPNVLGMAINPAIR---------------------
.
Mvan_4427|M.vanbaalenii_PYR-1 ----GGGLLSSPNPHPDLIRLLTTDAGQFTWAAAVVGSNNAAGYQLASGA
MSMEG_4988|M.smegmatis_MC2_155 ----GGGPFSAPTPGEALTATLAADADNYTWAAAVVGSSNAAGYQLATGA
MAB_0927|M.abscessus_ATCC_1997 ASKRGGSLLDGSDPGPNIVAALNDNADRYTWVAAAIGSNQASGYQLATRR
Mflv_2269|M.gilvum_PYR-GCK ----GPGGPAGPDGDNTELQELVRSADN-RWAAAGVGSMLTGDLQLRTGA
Mb3821|M.bovis_AF2122/97 -----RVTGKRRDRTVVLTADYSFLSYYPYWGFQGLTPHYANPLAQFDKR
Rv3792|M.tuberculosis_H37Rv -----RVTGKRRDRTVVLTADYSFLSYYPYWGFQGLTPHYANPLAQFDKR
MAV_3138|M.avium_104 ------------TLWDGHVAIWLTTAKINKCSTIWTITNKDNSLPDHQSG
MMAR_2338|M.marinum_M -----ESAEPIMRAGIDQASCVVDATNVKRPQCPPLRSEHPLGYCLPPTV
: .
Mvan_4427|M.vanbaalenii_PYR-1 PVMAVGGFNGTDPSPTLEQFVADVQAGRIHYFVVGPRLMMGRSG---TET
MSMEG_4988|M.smegmatis_MC2_155 PVMAVGGFNGTDPAPTLAEFEELVAGRQIHYFIR-SRIMGARPGHTPTGS
MAB_0927|M.abscessus_ATCC_1997 PVMPIGGFNGTDPSPTLAQFQQYVADGQIHYFIDGERGSHGDEGFGPPGS
Mflv_2269|M.gilvum_PYR-GCK SVMAIGGFTGGDNAPTLEQFQQYVADGQVRYFIAGGHGGPG------GGA
Mb3821|M.bovis_AF2122/97 ATQIDSWSGLSTADEFIAALDKLPWQPPTVFLMRHGAHNSYTLRLAQDVY
Rv3792|M.tuberculosis_H37Rv ATQIDSWSGLSTADEFIAALDKLPWQPPTVFLMRHGAHNSYTLRLAQDVY
MAV_3138|M.avium_104 QSLPPGSAFGQAPAYRFPGYLGFHIVERWQFHYSQVVKSTR---------
MMAR_2338|M.marinum_M TLARIYPQLSELVRQQFHTVPIIDGCDGCTFYVRSAFEASS---------
: :
Mvan_4427|M.vanbaalenii_PYR-1 TESAAIRDWVEARYLELTVDGTVVYDLTQGAGNLTGGA----
MSMEG_4988|M.smegmatis_MC2_155 QEAAEIARWVQAHFTPITIDDVTIYDLTQRVPNTPIS-----
MAB_0927|M.abscessus_ATCC_1997 ETSKSIREWVQRTFTKKTIDDVEVYDLTGH------------
Mflv_2269|M.gilvum_PYR-GCK RSASQITAWVTQTFAPRDVGGTAVYDLQR-------------
Mb3821|M.bovis_AF2122/97 PNQPNVRRYTVDLRTALFADPRFVVEDIGPFVLAIRKPQESA
Rv3792|M.tuberculosis_H37Rv PNQPNVRRYTVDLRTALFADPRFVVEDIGPFVLAIRKPQESA
MAV_3138|M.avium_104 ------------------------------------------
MMAR_2338|M.marinum_M ------------------------------------------