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M. smegmatis MC2 155 MSMEG_2188 (-)

annotation: integral membrane protein
coordinates: 2267604 - 2268578
length: 324

LFGAMSVIWGIPYLLIKVAVEGVSVPVLVLARTAVGALVLLPLAMSRAAWAPVLRHWKPVLVFAFFEIIA
AWALLTDAERHLTSSMTGLLIAAAPIIAAVLDRITGGERLGVKRVAGLFVGLSGVAVLAGPGLAGGHVWP
VLEVLLVATCYAIAPLVAARFLGEVPSLPMTAACLTVAALIYTTPAALTWPDAMPSTRVLAALAALAVVC
TALAFIVFFALIREVGAARALVFTYVNPAVALAAGVIVLGEPLTAYNIAGLVLILSGSVLATRKATHGNR
ERETSAKNQPDSRSQFTLAEPIEAIEPIEPKGPTGPGATRRTP*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_2188--100% (324)integral membrane protein
M. smegmatis MC2 155MSMEG_0468-5e-1329.01% (262) integral membrane protein
M. smegmatis MC2 155MSMEG_2542-2e-1025.86% (263) hypothetical protein MSMEG_2542

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_4964-7e-1126.62% (293) hypothetical protein Mflv_4964
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0766-1e-2226.43% (280) integral membrane protein
M. marinum MMMAR_4903-2e-1125.78% (287) hypothetical protein MMAR_4903
M. avium 104MAV_0095-1e-1225.80% (283) hypothetical protein MAV_0095
M. thermoresistible (build 8)TH_0035-7e-0526.58% (301) integral membrane protein
M. ulcerans Agy99MUL_0503-5e-1226.13% (287) hypothetical protein MUL_0503
M. vanbaalenii PYR-1Mvan_5539-1e-11676.45% (276) hypothetical protein Mvan_5539

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_2188|M.smegmatis_MC2_155      ---------------MLFGAMSVIWGIPYLLIKVAVEGVSVP--------
Mvan_5539|M.vanbaalenii_PYR-1       ---------MSLRGWLLFTAMGVIWGIPYLLIKVAVEGLSVP--------
Mflv_4964|M.gilvum_PYR-GCK          ----MAALDSSVTSRTQARADHFRSGLLFALASAFAFGCSGP---FAKAL
TH_0035|M.thermoresistible__bu      ----LARIHSAVN--------HFRLGLVFAIASASAFGMSGP---LAKSL
MMAR_4903|M.marinum_M               -------------------MPALAMGVTVTLWAFAFVGVRSAGRVFSPGV
MUL_0503|M.ulcerans_Agy99           ------MASSTTSSQRTVNMPALAMGVTVTLWAFAFVGVRSAGRVFSPGV
MAB_0766|M.abscessus_ATCC_1997      MDTATAAPARSRWLPLQFAALALVWGASFLFIKVGLQGLSAL--------
MAV_0095|M.avium_104                ------------MPLTTASAVTFFYALGYPIGTLAVVAMTPM--------
                                                          .  .    :      .            

MSMEG_2188|M.smegmatis_MC2_155      ---------VLVLARTAVGALVLLPLA---MSRAAWAPVLRHWKPVLVFA
Mvan_5539|M.vanbaalenii_PYR-1       ---------VLVFARTAVGALVLIPLT---LRRGAWAPVLAHWRPVVAFA
Mflv_4964|M.gilvum_PYR-GCK          MTAG-WSPTAAVTARLAGGALAMAVFATVVRPGWVR-EARHHARTVVLYG
TH_0035|M.thermoresistible__bu      LEAG-WSPAAAVTARLTGGALVLALFATAIKPGWLR-EAVRHRHTVVLYG
MMAR_4903|M.marinum_M               LALSRLFIAVMVMAVIATIAATYTAYAGRATTRRLRPPSAAALTLVIAYG
MUL_0503|M.ulcerans_Agy99           LALSRLFIAVMVMAVIATIAATYTAYAGRATTRRLRPPSAAALTLVIAYG
MAB_0766|M.abscessus_ATCC_1997      ---------QVAAARLDFGALTLVSLLVLLRVPLPR--EIKVWGHIAVVS
MAV_0095|M.avium_104                ---------AALVLRFGLAAMVLAVWTAIAKAGWPR--GARLGHVIVAGL
                                                       * .                       :    

MSMEG_2188|M.smegmatis_MC2_155      FFEIIAAWALLTDAERHLTSSMTGLLIAAAPIIAAVLDRITGGER-LGVK
Mvan_5539|M.vanbaalenii_PYR-1       FFEIIAAWLLLSDAERHITSSLTGLLIAAAPIVAALLDRLTGGDQPLTVK
Mflv_4964|M.gilvum_PYR-GCK          IVPIAGAQLFYFNAVAHLSVGVALLLEYTAPLLVVGWLWATTRHR-PSGM
TH_0035|M.thermoresistible__bu      IVPVAGTQLAYYHAVSHLSVGVALLLEYTAPILVVGWLWLVHRRT-PARL
MMAR_4903|M.marinum_M               VAWFGAYSIVISWAEQHIDAGTTALLVNLAPILVAVFAGFFLGEG-YSAR
MUL_0503|M.ulcerans_Agy99           VAWFGAYSIVISWAEQHIDAGTTALLVNLAPILVAVFAGFFLGEG-YSAR
MAB_0766|M.abscessus_ATCC_1997      LTLCVMPFVLYPWAEQTIDSGLASIYNAATPLMTTLVTLLALRAERPDRT
MAV_0095|M.avium_104                LIQGVQFCCLYEAVQLGAPAVLCAVMIAMNPVATAILAATFLREP-LGVQ
                                    .            .          :     *: ..               

MSMEG_2188|M.smegmatis_MC2_155      RVAGLFVGLSGVAVLAGPGL------AGGHVWPVLEVLLVATCYAIAPLV
Mvan_5539|M.vanbaalenii_PYR-1       RLAGLGTGLAGVAVLAGPEL------AGGSAWPVTEVLLVAVCYAIAPLI
Mflv_4964|M.gilvum_PYR-GCK          TLAGVVLAVGGITLVLGIIGPGGVAAAHINLAGVGWGLAAAVCAACYFLM
TH_0035|M.thermoresistible__bu      TLAGTALAVGGMTLVLDVFS-----GAHFDVVGLAWGLTAAVCSASYFLM
MMAR_4903|M.marinum_M               LLTGIAIAFAGVVLISAGGG-----GSQTDWLGVGLGLLAAVLYAAGVLL
MUL_0503|M.ulcerans_Agy99           LLTGIAIAFAGVVLISAGGG-----GSQTDWLGVGLGLLAAVLYAAGVLL
MAB_0766|M.abscessus_ATCC_1997      QLLGLALGFLGVCVVLAPWQLIG---HGGPVLAQFACLAATLSYGIGFVY
MAV_0095|M.avium_104                RTVALVLGVLAVLAACSQRLMS----THGVDPVIVLLFVALLGLSAGGVY
                                       .   .. .:                         : .    .   : 

MSMEG_2188|M.smegmatis_MC2_155      AARFLGEVP-----------SLPMTAACLTVAALIYTTP----------A
Mvan_5539|M.vanbaalenii_PYR-1       AARYLAEVP-----------AMPLTAACLGLAALIYVGP----------A
Mflv_4964|M.gilvum_PYR-GCK          SDKAGAMSDKEVADGRPSLHPITLAAAGLAFGAVTVAALGFSGLMPLAFT
TH_0035|M.thermoresistible__bu      SDRVGTGED--------GLHPVTLAAGGLLVGAVTVATAGAVGIAPLTFT
MMAR_4903|M.marinum_M               QKVALRTVD-----------ALSATLWGTLVGFIVTLPF-------LPAA
MUL_0503|M.ulcerans_Agy99           QKVALRTVD-----------ALSATLWGTLVGFIVTLPF-------LPAA
MAB_0766|M.abscessus_ATCC_1997      MRKYVTPLR---------LPALTVAAIQVGLGAVLMTAV---------VA
MAV_0095|M.avium_104                QQRFCGGVD-----------FRAMSALQNGVALLPAAGL----------A
                                                          . :     .. :               :

MSMEG_2188|M.smegmatis_MC2_155      ALTWPDAMPSTRVLAALAALAVVCTALAFIVFFALIREVGAARALVFTYV
Mvan_5539|M.vanbaalenii_PYR-1       AATWPAEIPSMRVLTAVALLAVVCTSLAFILFFALIREVGAPRALVITYV
Mflv_4964|M.gilvum_PYR-GCK          ANDAVIAGFTTPWIVPVIALALIPTAIAYTLGIVGIARLRPRFASMVGLS
TH_0035|M.thermoresistible__bu      TGDTVIAGVTMSWLVPVIGLGVIATAIAYTLGIIGIALLRPRFASLVGLS
MMAR_4903|M.marinum_M               ARELSLASAADLWWLVFLGAG--PSAIAFTTWAYALARTNAGVTAATTLM
MUL_0503|M.ulcerans_Agy99           ARELSLASAADLWWLVFLGAG--PSAIAFTTWAYALARTNAGVTAATTLM
MAB_0766|M.abscessus_ATCC_1997      LVDPHRIVATSAVVLSMLALGMLGTGLAYVWNTHIINGWGATAASSVTYL
MAV_0095|M.avium_104                MLTPFGVHDGRKALVAVAAMVLLNATLAVSLYVRAINAHGAAAVAMLFAV
                                                    .       : :*       :    .  .      

MSMEG_2188|M.smegmatis_MC2_155      NPAVALAAGVIVLGEPLTAYNIAGLVLILSGSVLATRKATHGNRERETSA
Mvan_5539|M.vanbaalenii_PYR-1       NPAVALAAGVIVLNEPLTARHLLGLAMILAGSVLATRRP-----------
Mflv_4964|M.gilvum_PYR-GCK          EVMFAVLAAWMLLGEGMAAAQVIGGAIVLAGLALARQGDRGELVGETNVG
TH_0035|M.thermoresistible__bu      EVMFATVAAWLLIGETVTPVQAVGGVIVLTGLALARQGDR----------
MMAR_4903|M.marinum_M               VPALVIALSGLLLAEVPNPLGLAGGGACLIGVALARGLLRLPARSRRRTG
MUL_0503|M.ulcerans_Agy99           VPALVIALSGLLLAEVPNPLGLAGGGACLIGVVLARGLLRLPARSRRRTG
MAB_0766|M.abscessus_ATCC_1997      TPVIGVLLGALLLGEHIGWHEPLGGAIVIAGIVVSRRGSR----------
MAV_0095|M.avium_104                IPAVAAVLSWIILGQRPDQGVAAGLVLGGLACWVNTRAAS----------
                                       .    . ::: :        *      .  :                

MSMEG_2188|M.smegmatis_MC2_155      KNQPDSRSQFTLAEPIEAIEPIEPKGPTGPGATRRTP
Mvan_5539|M.vanbaalenii_PYR-1       ------------VEPMQAAPR----------------
Mflv_4964|M.gilvum_PYR-GCK          E-TSVTPTALPQTTPVARGGPATIDP-----------
TH_0035|M.thermoresistible__bu      ---PVPGTGDTPTTPVDDGPDRRVPELH---------
MMAR_4903|M.marinum_M               TGDQLQGVESLPVGLSDYAASSTAPSGRQL-------
MUL_0503|M.ulcerans_Agy99           TGDQLQGVESLPVGLSDYAASSTAPSGRQL-------
MAB_0766|M.abscessus_ATCC_1997      -------------------------------------
MAV_0095|M.avium_104                -------RPRTQRDGVPAAAPAELQSVSR--------