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MDRFAGRRAIVTGAGSGIGAATAARLLDEGATIVAYDISAEGLARTRAAADDAGTGKRLTTAVLDISVEG DVIAAVDAAVADLGGLEVLVNVAAIQTCSHTHQTTLADWNRTLAVNLTGTFLMTRQALPALLDSGRGVVV NFTSTAASFAHPYMAAYAASKGGILSFTHSLALEYAKQGLRAVNIQPGGVSTALANSTLDKMPDGYDVGL WAKQTPLLHGKDSEILGDPSAVASVIAMVASDDGAFITGTEIRVDGGAHA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3034 | - | - | 100% (260) | oxidoreductase |
| M. avium 104 | MAV_0672 | - | 3e-79 | 56.27% (263) | oxidoreductase |
| M. avium 104 | MAV_1395 | - | 2e-37 | 37.85% (251) | 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1976 | - | 4e-35 | 34.77% (256) | short-chain type dehydrogenase/reductase |
| M. gilvum PYR-GCK | Mflv_4541 | - | 5e-65 | 49.24% (264) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1941 | - | 4e-35 | 34.77% (256) | short-chain type dehydrogenase/reductase |
| M. leprae Br4923 | MLBr_01094 | - | 3e-24 | 30.34% (267) | short chain alcohol dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0073c | - | 4e-26 | 29.30% (273) | putative short chain dehydrogenase/reductase |
| M. marinum M | MMAR_4967 | - | 3e-81 | 57.03% (263) | short-chain type dehydrogenase/reductase |
| M. smegmatis MC2 155 | MSMEG_2852 | - | 8e-69 | 51.89% (264) | 3-oxoacyl- |
| M. thermoresistible (build 8) | TH_2959 | - | 1e-66 | 50.00% (264) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_4041 | - | 9e-82 | 57.03% (263) | short-chain type dehydrogenase/reductase |
| M. vanbaalenii PYR-1 | Mvan_2848 | - | 2e-65 | 49.62% (266) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1976|M.bovis_AF2122/97 ---------MNHPDLAGKVAIVTGAGAGIGLAVARRLADEGCHVLCADID
Rv1941|M.tuberculosis_H37Rv ---------MNHPDLAGKVAIVTGAGAGIGLAVARRLADEGCHVLCADID
Mflv_4541|M.gilvum_PYR-GCK ------------MRYSGRRVLITGGGSGIGQACALRILAEGGRVAAADIS
Mvan_2848|M.vanbaalenii_PYR-1 MSATPTGSSPQLTRYAGRRVLITGGGSGIGQACVLRILAEGGRVVAADIS
MSMEG_2852|M.smegmatis_MC2_155 MPDLQAESPIAPSRYAGRRVLITGGGSGIGQACVLRILAEGAQVVAADIS
TH_2959|M.thermoresistible__bu -------VSDLSARYAARRVLITGGGSGIGQACVLRILAEGGRVAAADIS
MMAR_4967|M.marinum_M -----------MTRLVGQRILVTGAGSGIGQATVLRLLDEGATVVGADID
MUL_4041|M.ulcerans_Agy99 -----------MTRLVGQRILVTGAGSGIGQATVLRLLDEGATVVGADID
MAV_3034|M.avium_104 -----------MDRFAGRRAIVTGAGSGIGAATAARLLDEGATIVAYDIS
MAB_0073c|M.abscessus_ATCC_199 -----------MTRLGGRVAVVTGAGKGMGRTHCERLAEEGSDVIAIDLP
MLBr_01094|M.leprae_Br4923 -----------MEGFAGKVAVVTGAGSGIGQALAIELARSGAKLAISDVD
.: ::**.* *:* : .: .* : *:
Mb1976|M.bovis_AF2122/97 G-DAADAAATKIGCGAA-----ACRVDVSDEQQIIAMVDACVAAFGGVDK
Rv1941|M.tuberculosis_H37Rv G-DAADAAATKIGCGAA-----ACRVDVSDEQQIIAMVDACVAAFGGVDK
Mflv_4541|M.gilvum_PYR-GCK G-DGLADTVQKAGDLAT--NLMTVVMDVGDEPSVSSGVAEAIAALGGLDT
Mvan_2848|M.vanbaalenii_PYR-1 A-DGLADTAEKAGALGT--GLSTVVMDVGDEQSVSAGLAEALNTLGGLDT
MSMEG_2852|M.smegmatis_MC2_155 P-EGLDDTTGKAGEFSS--RLTTVTLDVGDEDSVRAGVAAAVAELGGLDT
TH_2959|M.thermoresistible__bu P-SGLRDTVNQAGAAAE--RLTTVTMDVADEQSVRHGVGQAITALGGLDA
MMAR_4967|M.marinum_M A-AGLSRTQARTAEAGTGARLTTCQIDVADEKSVVDGVGAAVQALGGLDA
MUL_4041|M.ulcerans_Agy99 A-DGLSRTQARTAEAGTGARLTTCQIDVADEKSVVDGVGAAVQALGGLDA
MAV_3034|M.avium_104 A-EGLARTRAAADDAGTGKRLTTAVLDISVEGDVIAAVDAAVADLGGLEV
MAB_0073c|M.abscessus_ATCC_199 GSDDLAQTAAAVEEHGR--RCVWAFADVRDAAALTEAIDTGVRMLGRLDI
MLBr_01094|M.leprae_Br4923 G-EGLAQTEGQLKAIGAS--ARTDRLDVTEREAFLTYADVVHENFGKVNQ
: . *: . :* ::
Mb1976|M.bovis_AF2122/97 LVANAGVVH-LASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERGGG
Rv1941|M.tuberculosis_H37Rv LVANAGVVH-LASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERGGG
Mflv_4541|M.gilvum_PYR-GCK LVNAAGILR-SAHLADTTLADFEQVLRINLIGTFLVTRESLAALRDGRGP
Mvan_2848|M.vanbaalenii_PYR-1 LVNAAGILR-SAHLAQTTLADFEQVLRINLIGTFLVTREAVTALHQGDGS
MSMEG_2852|M.smegmatis_MC2_155 LVNAAGILR-SSHLAQTSLADFEQVLRINLTGTFLVTREAIGALLEGHRP
TH_2959|M.thermoresistible__bu LVNAAGILR-SAHLVQTTLADFEQVIRINLTGTFLVTRECIPALLDGNGP
MMAR_4967|M.marinum_M LVNAAGMLR-AAHTHQTSIQQWNQIIAVNLTGTFLVVREALPALLDNQRS
MUL_4041|M.ulcerans_Agy99 LVNAAGMLR-AAHTHQTSIQQWNQIIAVNLTGTFLVVREALPALLDNQRS
MAV_3034|M.avium_104 LVNVAAIQT-CSHTHQTTLADWNRTLAVNLTGTFLMTRQALPALLDSGRG
MAB_0073c|M.abscessus_ATCC_199 VVANAGVYDGLAPSCELTEDSWRRALDVNLTGAWHTVKAGAAHLLD--GG
MLBr_01094|M.leprae_Br4923 IYNNAGIAF-TGDVEVSHFKDIERVMDVDYWGVVNGTKAFLPYLISSGDG
: *.: . . : : :: *. .: : .
Mb1976|M.bovis_AF2122/97 AIVNLSSLAGQVAVGGTGAYGMSKAGIIQLSRITAAELRSSG--IRSNTL
Rv1941|M.tuberculosis_H37Rv AIVNLSSLAGQVAVGGTGAYGMSKAGIIQLSRITAAELRSSG--IRSNTL
Mflv_4541|M.gilvum_PYR-GCK AVVNFSSTSAHFAHPYMAAYAASKGGVLAMTHAWALEFAKAG--IRFNCV
Mvan_2848|M.vanbaalenii_PYR-1 AVVNFSSTSAQFAHPYMAAYAASKGGVLAMTHAWALEFAKAG--IRFNCV
MSMEG_2852|M.smegmatis_MC2_155 AVVNFSSTSAHFAHPYMAAYAASKGGVLAMTHAWALEFAKAG--IRFNSV
TH_2959|M.thermoresistible__bu AVVNFSSTSAHFAHPYMAAYAASKGGVLAMTHTWAAEFAKAG--IRFNAV
MMAR_4967|M.marinum_M TVVNFSSTSAAFAHPYMAAYAASKGGVQAFTHSLALEYARDG--LRAVCV
MUL_4041|M.ulcerans_Agy99 TVVNFSSTSAAFAHPYMAAYAASKGGVQAFTHSLALEYARDG--LRAVCV
MAV_3034|M.avium_104 VVVNFTSTAASFAHPYMAAYAASKGGILSFTHSLALEYAKQG--LRAVNI
MAB_0073c|M.abscessus_ATCC_199 SVIIISSTNGLKGTANTAHYTASKHAVVGLARTAANELGPQG--IRVNTV
MLBr_01094|M.leprae_Br4923 HVINISSVFGLFSVPGQAAYNSAKFAVRGFTEALREEMALAGRPVNVTTV
:: ::* . . . * :* .: ::. * * :. :
Mb1976|M.bovis_AF2122/97 LPAFVDTPMQQT---AMAMFDG---ALGAGGARSMIARLQ----------
Rv1941|M.tuberculosis_H37Rv LPAFVDTPMQQT---AMAMFDG---ALGAGGARSMIARLQ----------
Mflv_4541|M.gilvum_PYR-GCK QPGSISSGMTDG---TGASRQSVGPGLPEDADYALFGKVAPMLP------
Mvan_2848|M.vanbaalenii_PYR-1 QPGSISSGMTDG---TGASRQSIGPGLPEDADYTLFAKVAPMLP------
MSMEG_2852|M.smegmatis_MC2_155 QPGSISSGMTDG---TGASRQSIGPGLPEDADFSLFGKVAPMLP------
TH_2959|M.thermoresistible__bu QPGSISSGMTDG---SGVSRQSVGPGLPEDADLALFAKVAPALP------
MMAR_4967|M.marinum_M APGSIKSGITDA---TGG-------YIPADANWSLFTRLMPILPT-----
MUL_4041|M.ulcerans_Agy99 APGSIKSGITDA---TGG-------YIPADANWSLFTRLMPILPT-----
MAV_3034|M.avium_104 QPGGVSTALANS---TLD-------KMPDGYDVGLWAKQTPLLHG-----
MAB_0073c|M.abscessus_ATCC_199 HPGAVSTGMILNPAVIARLRPDLEHPTVEDAAEALAARTLLPVP------
MLBr_01094|M.leprae_Br4923 YPGGIKTAIARN----ATAAEGLDVSKIASRFDTWVAHTSPQHAARIILK
*. :.: : . :
Mb1976|M.bovis_AF2122/97 -------GRMAAPEEMAGIVVFLLSDDASMITGTTQIADGGTIAALW
Rv1941|M.tuberculosis_H37Rv -------GRMAAPEEMAGIVVFLLSDDASMITGTTQIADGGTIAALW
Mflv_4541|M.gilvum_PYR-GCK ---LDDGAIFAAPDAVAGVVAMLGSSDAYFITGTEVRIDGGSHM---
Mvan_2848|M.vanbaalenii_PYR-1 ---LDGGAIFAAPDAVAGVVAMLGSRDAYFITGTEVRIDGGSHM---
MSMEG_2852|M.smegmatis_MC2_155 ---LDGGAIFARPDAVAGVVAMLGSADAYFITGTEVRIDGGSHM---
TH_2959|M.thermoresistible__bu ---LGDGTIFADPDAVAGVVAMLGSDDAFFITGTEVRIDGGAHM---
MMAR_4967|M.marinum_M -TETSSGAGMADPSVVAGVIAMLVSEDGAFITGTEIRIDGGTHA---
MUL_4041|M.ulcerans_Agy99 -TETSSGAGMADPSVVAGVIAMLVSEDGAFITGTEIRIDGGTHA---
MAV_3034|M.avium_104 ----KDSEILGDPSAVASVIAMVASDDGAFITGTEIRVDGGAHA---
MAB_0073c|M.abscessus_ATCC_199 ---------WVEAVDISNAVVFLASDEARYITGTQLVVDAGLTQKA-
MLBr_01094|M.leprae_Br4923 AVRKKKARVLVGPDAKVANVVVRFSGGAGYQRLFAQVASRLILNQR-
. :.. * . .