For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTVTSASATERESDPTRGERTRAAILNASRRLFLERGYAGTPINAITEACGISRAGFYTYFKDKREIFNV LGKNAYREALAVIGEWAEADAAFGPADIRAWVGHYFDYMDHHGAFVLASAQSAPDDDDFRNSRNRMVTRA SWKLGQAIAGNGTHSPDAIGVAVMGLLDRAWHTVHRQTVAVDRDEMIAVVAEMILAMAVTSGPLAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2578 | - | - | 100% (206) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_1852 | - | 3e-93 | 83.84% (198) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_2546 | - | 3e-32 | 38.25% (183) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0310 | - | 9e-10 | 34.52% (84) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4467 | - | 4e-11 | 31.18% (170) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0302 | - | 9e-10 | 34.52% (84) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01070 | - | 4e-06 | 25.83% (120) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2290 | - | 3e-10 | 37.23% (94) | transcriptional regulator TetR |
| M. marinum M | MMAR_1492 | - | 6e-10 | 29.81% (161) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_2290 | - | 2e-09 | 36.17% (94) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3297 | - | 5e-31 | 38.22% (191) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_2448 | - | 1e-09 | 29.19% (161) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_1893 | - | 3e-10 | 42.47% (73) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4467|M.gilvum_PYR-GCK ------------MPPGS-SDALSAKG----RQTRDALAQAARKLFAERGF
Mvan_1893|M.vanbaalenii_PYR-1 ------------MPPGP-AESLSAKG----RQTRDAIEQAARKLFAERGF
MMAR_1492|M.marinum_M ------------MPARQESRELSSKG----RQTRQAIEQAARKLFAERGF
MUL_2448|M.ulcerans_Agy99 ------------MPARQESRELSSKG----RQTRQAIEQVARKLFAERGF
MAV_2578|M.avium_104 ------------MTVTSASATERESDPTRGERTRAAILNASRRLFLERGY
TH_3297|M.thermoresistible__bu ------------MDSDAAAPGVRKSD-----RTRLTILDAARVAFARKGF
Mb0310|M.bovis_AF2122/97 ------------MGVPAKKKQQQGE------RSRESILDATERLMATKGY
Rv0302|M.tuberculosis_H37Rv ------------MGVPAKKKQQQGE------RSRESILDATERLMATKGY
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSG----DDREQAILAVAERLLAERPL
MSMEG_2290|M.smegmatis_MC2_155 MTAESVPQGSNGSAGATAAQARRSRG----DRQREAIVAAVRELLEEQPF
MAB_2290|M.abscessus_ATCC_1997 ------------MSESKPGRRERYAA-----LTRSAIVEAARMLFVERGF
. :: . . : :
Mflv_4467|M.gilvum_PYR-GCK HGTTLSDITSAAGKSPAAFYRYFSDKEDLLAALAESFLHEVVA-PSGLSV
Mvan_1893|M.vanbaalenii_PYR-1 HGTTLGDITSAAGKSPAVFYRYFADKEDLLAALAESFLHDVVA-PSGLSV
MMAR_1492|M.marinum_M HGTTLADITSAAGKSSAVFYRYFTDKEDLLAALAQSFLHDVVT-PSGVSL
MUL_2448|M.ulcerans_Agy99 HGTTLADITSAAGKSSAVFYRYFTDKEDLLAALAQSFLHDVVT-PSGVSL
MAV_2578|M.avium_104 AGTPINAITEACGISRAGFYTYFKDKREIFNVLGKNAYREALA-VIGEWA
TH_3297|M.thermoresistible__bu SGVTIRDITDLAGVTRANFYYYFKDKTELFVELGTATYREVLE-VIETFS
Mb0310|M.bovis_AF2122/97 AATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFA-AIPTWD
Rv0302|M.tuberculosis_H37Rv AATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFA-AIPTWD
MLBr_01070|M.leprae_Br4923 GDFSVDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRS-AVEALA
MSMEG_2290|M.smegmatis_MC2_155 ADISVSTISERAGVARSGFYFYFDSKYAVLAVILAEAMEELDA-LTHNFA
MAB_2290|M.abscessus_ATCC_1997 DDTSVDDIAEAAQVSKGAIYHHFKDKQEIFIDVYRDATKGVIENVVKVLI
.: : . . : :* :* .* :: :
Mflv_4467|M.gilvum_PYR-GCK PLPESPD--DDAFFTAVVTGYWTMFKQNIGIMIAVAQLAATQPRFTLVQN
Mvan_1893|M.vanbaalenii_PYR-1 PLPESPD--DDAFFTMVVTGYWTMFKQNIGIMIAVAQLAATQSRFALVQN
MMAR_1492|M.marinum_M QLPDSPD--DDTFFTAVVTGYWNIFKQNIGIMIAVDQLAATQQRFAAVQN
MUL_2448|M.ulcerans_Agy99 QLPDSPD--DDTFFTAVVTGYWNIFKQNIGIMIAVDQLAATQQRFAAVQN
MAV_2578|M.avium_104 EADAAF---GPADIRAWVGHYFDYMDHHGAFVLASAQSAPDDDDFRNSRN
TH_3297|M.thermoresistible__bu DTAS------PVIIDQWVSRYFTYLDRNGAFVIRSEEDMPQDGAFRTAVA
Mb0310|M.bovis_AF2122/97 EAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS-QDPVVAAVVR
Rv0302|M.tuberculosis_H37Rv EAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS-QDPAVAAVVR
MLBr_01070|M.leprae_Br4923 EQLPADP---AAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWS
MSMEG_2290|M.smegmatis_MC2_155 PRGENES--PAAFAKRMVGSAAAVYATNDPVMSACTVAQNTDAQIRDIMN
MAB_2290|M.abscessus_ATCC_1997 DVPAGSWNRIEAAASAVIKGYTDNREPR--VLVRQVMGVLGAERTQALEG
: .
Mflv_4467|M.gilvum_PYR-GCK EFRRFGMDIVAASVRRAQEQGYGTELNPEHTAAAIALLFENFTTVFVGAS
Mvan_1893|M.vanbaalenii_PYR-1 EFRRFGMDIVAASVRRAQEQGYGRELNAEHTAAAIALLFENFTTVFVGAS
MMAR_1492|M.marinum_M QFRRFGMDIIAASVRHAQDQGYGTELNPDHTAVAIALLFENFTSVLVGTS
MUL_2448|M.ulcerans_Agy99 QFRRFGMDIIAASVRHAQDQGYGTELNPDHTAVAIALLFENFTSVLVGTS
MAV_2578|M.avium_104 RMVTRASWKLGQAIAGNG----THSPDAIGVAVMGLLDRAWHTVHRQTVA
TH_3297|M.thermoresistible__bu RSHRRAAQALGQQIAKASSTPLAADEAATGLVVMAMLERSWLIHHNGVFD
Mb0310|M.bovis_AF2122/97 RVRNTAIARFRDSITHLLPS--DIPPGKADLVVAELTAFAVALSDGVYFA
Rv0302|M.tuberculosis_H37Rv RVRNTAIARFRDSITHLLPS--DIPPGKADLVVAELTAFAVALSDGVYFA
MLBr_01070|M.leprae_Br4923 TVMQQWIDYNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSD
MSMEG_2290|M.smegmatis_MC2_155 DFEDATIAKIVGVIEQDT----GARPISDDLPALVRTLTATTAMTLSRDA
MAB_2290|M.abscessus_ATCC_1997 ELALPLIRTLLTEAEENGELRDLSIEKASQLIFRVLCESSLLIANSADYA
Mflv_4467|M.gilvum_PYR-GCK G------LGVQMTDQDAIATLSRIWKKTLYGY------------------
Mvan_1893|M.vanbaalenii_PYR-1 G------LDVDIDDEAAIATLSRIWKKTLYGY------------------
MMAR_1492|M.marinum_M GSSGPGGLGVTITDEDAITTLSRIWKKTLYGF------------------
MUL_2448|M.ulcerans_Agy99 GSSGPGGLGVTITDEDAITTLSRIWKKTLYGF------------------
MAV_2578|M.avium_104 VDRDEMIAVVAEMILAMAVTSGPLAS------------------------
TH_3297|M.thermoresistible__bu APRDVVLAAASEVIRRLVEDDGRPGTSIQEILPRVSVEPQRCRDGTQLEP
Mb0310|M.bovis_AF2122/97 GHLEPDTTDVERMYRRLRQALEALIPVLLEET------------------
Rv0302|M.tuberculosis_H37Rv GHLEPDTTDVERMYRRLRQALEALIPVLLEET------------------
MLBr_01070|M.leprae_Br4923 E-------KPLIPDKKVIDTLVHIWLASIYGS------------------
MSMEG_2290|M.smegmatis_MC2_155 G-----FVGRDADPARAVEIVERLWLSALWGGLPE---------------
MAB_2290|M.abscessus_ATCC_1997 EAAQEVETVMLCMFAGLRKPPAATRGRRKS--------------------
Mflv_4467|M.gilvum_PYR-GCK -----------------------------------
Mvan_1893|M.vanbaalenii_PYR-1 -----------------------------------
MMAR_1492|M.marinum_M -----------------------------------
MUL_2448|M.ulcerans_Agy99 -----------------------------------
MAV_2578|M.avium_104 -----------------------------------
TH_3297|M.thermoresistible__bu GRAPAQQALASHRHASGSTWPHRPEVIRATGRTQT
Mb0310|M.bovis_AF2122/97 -----------------------------------
Rv0302|M.tuberculosis_H37Rv -----------------------------------
MLBr_01070|M.leprae_Br4923 -----------------------------------
MSMEG_2290|M.smegmatis_MC2_155 -----------------------------------
MAB_2290|M.abscessus_ATCC_1997 -----------------------------------