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MVSEGSPPRATRKSDRTRESILDAARTAFARKGFSGVTIKDITDLAPVTRANFYYYFSDKTELFIELGTD TYREALAVVEGFMEQGSPPSREDVEAWVAGYFDYLDRNGAFVIRSTEDMPPDRKFRAAVARSHRRTAAAL GEGIAKMAPTPPDLDPVATGLVIMAMLERSWLMVRHNEVPSTTRQAVLMAATEMLWRTVNGQT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2546 | - | - | 100% (203) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_2578 | - | 2e-32 | 38.25% (183) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_1852 | - | 7e-32 | 36.32% (190) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0149 | - | 1e-08 | 36.05% (86) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4467 | - | 2e-10 | 34.78% (115) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0144 | - | 1e-08 | 36.05% (86) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 1e-05 | 25.15% (171) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2290 | - | 3e-10 | 39.19% (74) | transcriptional regulator TetR |
| M. marinum M | MMAR_1492 | - | 1e-09 | 33.60% (125) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_2071 | - | 4e-09 | 33.33% (126) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3297 | - | 2e-64 | 65.33% (199) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_2448 | - | 2e-09 | 32.80% (125) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_1893 | - | 1e-08 | 30.66% (137) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2546|M.avium_104 --------------------------------------------------
TH_3297|M.thermoresistible__bu --------------------------------------------------
Mb0149|M.bovis_AF2122/97 MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
Rv0144|M.tuberculosis_H37Rv MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
Mflv_4467|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1893|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1492|M.marinum_M --------------------------------------------------
MUL_2448|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2071|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2290|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00815|M.leprae_Br4923 -------------------------------------------------M
MAV_2546|M.avium_104 ----------------------MVSEGSPPRATRKSDRTRESILDAARTA
TH_3297|M.thermoresistible__bu ----------------------MDSDAAAP-GVRKSDRTRLTILDAARVA
Mb0149|M.bovis_AF2122/97 ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
Rv0144|M.tuberculosis_H37Rv ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
Mflv_4467|M.gilvum_PYR-GCK ----------------------MPPGS-SDALSAKGRQTRDALAQAARKL
Mvan_1893|M.vanbaalenii_PYR-1 ----------------------MPPGP-AESLSAKGRQTRDAIEQAARKL
MMAR_1492|M.marinum_M ----------------------MPARQESRELSSKGRQTRQAIEQAARKL
MUL_2448|M.ulcerans_Agy99 ----------------------MPARQESRELSSKGRQTRQAIEQVARKL
MSMEG_2071|M.smegmatis_MC2_155 --------------------------MASGELGSKGRQTRTAIELAARKL
MAB_2290|M.abscessus_ATCC_1997 -----------------------MSESKPGRRERYAALTRSAIVEAARML
MLBr_00815|M.leprae_Br4923 NNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASDV
* : .*
MAV_2546|M.avium_104 FARKGFSGVTIKDITDLAPVTRANFYYYFSDKTELFIELGTDTYREALAV
TH_3297|M.thermoresistible__bu FARKGFSGVTIRDITDLAGVTRANFYYYFKDKTELFVELGTATYREVLEV
Mb0149|M.bovis_AF2122/97 FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQT-HELVIV
Rv0144|M.tuberculosis_H37Rv FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQT-HELVIV
Mflv_4467|M.gilvum_PYR-GCK FAERGFHGTTLSDITSAAGKSPAAFYRYFSDKEDLLAALAESFLHEVVAP
Mvan_1893|M.vanbaalenii_PYR-1 FAERGFHGTTLGDITSAAGKSPAVFYRYFADKEDLLAALAESFLHDVVAP
MMAR_1492|M.marinum_M FAERGFHGTTLADITSAAGKSSAVFYRYFTDKEDLLAALAQSFLHDVVTP
MUL_2448|M.ulcerans_Agy99 FAERGFHGTTLADITSAAGKSSAVFYRYFTDKEDLLAALAQSFLHDVVTP
MSMEG_2071|M.smegmatis_MC2_155 FAERGFHGTTLADITSAAGKSPAVFYRYFTDKEDLLAALAESFLHDVVEP
MAB_2290|M.abscessus_ATCC_1997 FVERGFDDTSVDDIAEAAQVSKGAIYHHFKDKQEIFIDVYRDATKGVIEN
MLBr_00815|M.leprae_Br4923 FVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVSS
* :*: . . :*: * : : :* .* : : . :
MAV_2546|M.avium_104 VEGF---MEQGSPPSREDVEAWVAGYFDYLDRNG-AFVIRSTEDMPPDRK
TH_3297|M.thermoresistible__bu IETF---SDTASP---VIIDQWVSRYFTYLDRNG-AFVIRSEEDMPQDGA
Mb0149|M.bovis_AF2122/97 AGIERARREPTLMGRLAVVVDFAMEADAQYPAST-AFLATTVLESQRHPE
Rv0144|M.tuberculosis_H37Rv AGIERARREPTLMGRLAVVVDFAMEADAQYPAST-AFLATTVLESQRHPE
Mflv_4467|M.gilvum_PYR-GCK SGLS--VPLPESPDDDAFFTAVVTGYWTMFKQNI-GIMIAVAQLAATQPR
Mvan_1893|M.vanbaalenii_PYR-1 SGLS--VPLPESPDDDAFFTMVVTGYWTMFKQNI-GIMIAVAQLAATQSR
MMAR_1492|M.marinum_M SGVS--LQLPDSPDDDTFFTAVVTGYWNIFKQNI-GIMIAVDQLAATQQR
MUL_2448|M.ulcerans_Agy99 SGVS--LQLPDSPDDDTFFTAVVTGYWNIFKQNI-GIMIAVDQLAATQQR
MSMEG_2071|M.smegmatis_MC2_155 SGLN--LHLPDSPDDAEFFTSVVTGYWNMFKQNI-GIMIAVAQLAATQQR
MAB_2290|M.abscessus_ATCC_1997 VVKVLIDVPAGSWNRIEAAASAVIKGYTDNREPR-VLVRQVMGVLGAERT
MLBr_00815|M.leprae_Br4923 VQQA----LRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEPR
. .
MAV_2546|M.avium_104 FRAAVARSHRRTAAALGEGI-AKMAPTPPDLDPVATGLVIMAMLERSWLM
TH_3297|M.thermoresistible__bu FRTAVARSHRRAAQALGQQI-AKASSTPLAADEAATGLVVMAMLERSWLI
Mb0149|M.bovis_AF2122/97 LSRTENDAVRATREFLVWAV-NDAIERGELAADVDVSSLAETLLVVLCGV
Rv0144|M.tuberculosis_H37Rv LSRTENDAVRATREFLVWAV-NDAIERGELAADVDVSSLAETLLVVLCGV
Mflv_4467|M.gilvum_PYR-GCK FTLVQNEFRRFGMDIVAASV-RRAQEQGYGTELNPEHTAAAIALLFENFT
Mvan_1893|M.vanbaalenii_PYR-1 FALVQNEFRRFGMDIVAASV-RRAQEQGYGRELNAEHTAAAIALLFENFT
MMAR_1492|M.marinum_M FAAVQNQFRRFGMDIIAASV-RHAQDQGYGTELNPDHTAVAIALLFENFT
MUL_2448|M.ulcerans_Agy99 FAAVQNQFRRFGMDIIAASV-RHAQDQGYGTELNPDHTAVAIALLFENFT
MSMEG_2071|M.smegmatis_MC2_155 FAEVQNSFRRFGIDIVVASV-RRAQEQGHAVGLVPEHIGAAIALLFENFT
MAB_2290|M.abscessus_ATCC_1997 QALEGELALPLIRTLLTEAE-ENGELRDLSIEKASQLIFRVLCESSLLIA
MLBr_00815|M.leprae_Br4923 VAAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCARYWL
:
MAV_2546|M.avium_104 VRHNEVPSTTRQAVLMAATEMLWRTVN-----GQT---------------
TH_3297|M.thermoresistible__bu H-HNGVFDAPRDVVLAAASEVIRRLVEDDGRPGTSIQEILPRVSVEPQRC
Mb0149|M.bovis_AF2122/97 GFYIGFVG---SYQRMATITDSFQQLLAGTLWRPPT--------------
Rv0144|M.tuberculosis_H37Rv GFYIGFVG---SYQRMATITDSFQQLLAGTLWRPPT--------------
Mflv_4467|M.gilvum_PYR-GCK TVFVGASG------LGVQMTDQDAIATLSRIWKKTLYGY-----------
Mvan_1893|M.vanbaalenii_PYR-1 TVFVGASG------LDVDIDDEAAIATLSRIWKKTLYGY-----------
MMAR_1492|M.marinum_M SVLVGTSGSSGPGGLGVTITDEDAITTLSRIWKKTLYGF-----------
MUL_2448|M.ulcerans_Agy99 SVLVGTSGSSGPGGLGVTITDEDAITTLSRIWKKTLYGF-----------
MSMEG_2071|M.smegmatis_MC2_155 TVFVGSSG------LGVELDDREAITTLATIWKKTLYGF-----------
MAB_2290|M.abscessus_ATCC_1997 NSADYAEAAQEVETVMLCMFAGLRKPPAATRGRRKS--------------
MLBr_00815|M.leprae_Br4923 DTNRPISK---SDAVEGTVQFAWGGLSHVPLTRL----------------
MAV_2546|M.avium_104 -------------------------------------------
TH_3297|M.thermoresistible__bu RDGTQLEPGRAPAQQALASHRHASGSTWPHRPEVIRATGRTQT
Mb0149|M.bovis_AF2122/97 -------------------------------------------
Rv0144|M.tuberculosis_H37Rv -------------------------------------------
Mflv_4467|M.gilvum_PYR-GCK -------------------------------------------
Mvan_1893|M.vanbaalenii_PYR-1 -------------------------------------------
MMAR_1492|M.marinum_M -------------------------------------------
MUL_2448|M.ulcerans_Agy99 -------------------------------------------
MSMEG_2071|M.smegmatis_MC2_155 -------------------------------------------
MAB_2290|M.abscessus_ATCC_1997 -------------------------------------------
MLBr_00815|M.leprae_Br4923 -------------------------------------------