For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VKPFRIDVPDDVLDDLRARLARTRWPEAECVDDWSQGMPLAYTRELADYWANDYDWRAREAALNRFDQFV TEIDGLDIHFIHQRSPHADAFPLLITHGWPGSIVEFHKVIEPLTNPASGRGEDAFHVVCPSLPGYGFSGK PTRAGWGVERIARAWETLMLRLGYQRYGAQGGDWGAAVTTQIGRNRGHCVAIHLNMPIGRPGQEALTNPT EQERAALAALANHRKRGTGYSKQQSTRPQTLGYGLADSPVGQLAWIVEKFWDWADCDGHPENALSRDELL DNVMVYWVTNTAASSARLYWESFSAWGGGDRVELPTGVAAFPGELLKAPRSWCEPAYNITHWTDMPRGGH FAAFEQPELFVEDLRVFFATVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2202 | - | - | 100% (372) | epoxide hydrolase |
| M. avium 104 | MAV_5163 | - | 6e-05 | 27.59% (116) | hydrolase, alpha/beta fold family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1864c | - | 2e-06 | 28.42% (95) | haloalkane dehalogenase |
| M. gilvum PYR-GCK | Mflv_0644 | - | 0.0 | 77.54% (374) | epocide hydrolase domain-containing protein |
| M. tuberculosis H37Rv | Rv1833c | - | 2e-06 | 28.42% (95) | haloalkane dehalogenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4300 | - | 0.0001 | 31.03% (87) | putative hydrolase, alpha/beta fold |
| M. marinum M | MMAR_3314 | - | 0.0 | 82.35% (374) | hydrolase |
| M. smegmatis MC2 155 | MSMEG_5658 | - | 1e-170 | 74.19% (372) | epoxide hydrolase |
| M. thermoresistible (build 8) | TH_2132 | - | 2e-74 | 81.82% (154) | epoxide hydrolase 1 |
| M. ulcerans Agy99 | MUL_4778 | ephF | 3e-06 | 30.63% (111) | epoxide hydrolase EphF |
| M. vanbaalenii PYR-1 | Mvan_0521 | - | 0.0 | 77.54% (374) | epocide hydrolase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2202|M.avium_104 ------MKPFRIDVPDDVLDDLRARLARTRWPEAECVDDWSQGMPLAYTR
MMAR_3314|M.marinum_M ------MRPFRIDVPDDVIDDLKARLTRTRWPEAECVDDWSQGIPLSYTR
Mflv_0644|M.gilvum_PYR-GCK ---MRAVRPFSIHVADDVLDDLRTRLSRTRWPEAECVPDWTQGIPLGYTR
Mvan_0521|M.vanbaalenii_PYR-1 MSAVRAVRPFSIHVADDVLDDLRTRLSRTRWPEAECVPDWTQGIPLGYTR
MSMEG_5658|M.smegmatis_MC2_155 -MTDSLIRPFRIAVPDADLDDLKSRLSRTRWPEPETVDDWGQGIPLDYTR
TH_2132|M.thermoresistible__bu ---MPSVKPFRIAVPDDDLDDLRHRLARTRWPDRECVDDWGQGVPLDYVR
Mb1864c|M.bovis_AF2122/97 -------------------------------------------MSIDFT-
Rv1833c|M.tuberculosis_H37Rv -------------------------------------------MSIDFT-
MAB_4300|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4778|M.ulcerans_Agy99 --------------------------------------------------
MAV_2202|M.avium_104 ELADYWANDYDWRAREAALNRFDQFVTEIDG-LDIHFIHQRSPHADAFPL
MMAR_3314|M.marinum_M DLAAYWANEYDWRAREAALNRFDQFITEIDG-LDLHFIHQRSPHQDAFPL
Mflv_0644|M.gilvum_PYR-GCK ELAAYWADGYDWRSREAALNRFDQFVVEIHG-VDIHFIHQRSPHQEAFPL
Mvan_0521|M.vanbaalenii_PYR-1 ELAAYWADGYDWRSREAALNRFDQFVVEIHG-VDIHFIHQRSPHQEAFPL
MSMEG_5658|M.smegmatis_MC2_155 ELAEYWANGYDWRAREQALNRFDHYVTELDG-LDIHFIHQRCARPDAFPL
TH_2132|M.thermoresistible__bu DLAGYWADGYDWRAREAALNRFDQFITELDG-LDIHFIHQRSPHPDAFPL
Mb1864c|M.bovis_AF2122/97 --------------PDPQLYPFESRWFDSSR-GRIHYVDEG----TGPPI
Rv1833c|M.tuberculosis_H37Rv --------------PDPQLYPFESRWFDSSR-GRIHYVDEG----TGPPI
MAB_4300|M.abscessus_ATCC_1997 ------------MDAELEEWKAAGHYFDYLG-FDIFYRVEG----SGPPL
MUL_4778|M.ulcerans_Agy99 ------------MSTLPALDGVEHRFVDLDGGITIHVADAG--PADGPAV
: :. . .:
MAV_2202|M.avium_104 LITHGWPGSIVEFHKVIEPLTNPAS--GRGEDAFHVVCPSLPGYGFSGKP
MMAR_3314|M.marinum_M LITHGWPGSVVEFHKVIEPLTNPTAHGGRAEDAFHVVCPSLPGYGFSGKP
Mflv_0644|M.gilvum_PYR-GCK VITHGWPGSIVEFHNVIEPLTNPTAHGGRAEDAFHVVCPALPGYGFSGKP
Mvan_0521|M.vanbaalenii_PYR-1 VITHGWPGSIVEFHNVIEPLTNPTAHGGRAEDAFHVVCPALPGYGFSGKP
MSMEG_5658|M.smegmatis_MC2_155 LLTHGWPGSIVEFHKVIEPLT---------EAGFDVVCPSLPGYGFSGKP
TH_2132|M.thermoresistible__bu LITHGWPGSIVEFHKVIGPLTDPTAHGGTAADAFHVVCPSLPGYGFSGKP
Mb1864c|M.bovis_AF2122/97 LLCHGNPTWSFLYRDIIVALR----------DRFRCVAPDYLGFGLSERP
Rv1833c|M.tuberculosis_H37Rv LLCHGNPTWSFLYRDIIVALR----------DRFRCVAPDYLGFGLSERP
MAB_4300|M.abscessus_ATCC_1997 LLIHGYPFNSWDWALIWPTLV----------ERFTVIAPDMIGMGFSDKP
MUL_4778|M.ulcerans_Agy99 MLVHGFPENWWEWHELIGPLA---------ADGYRVLCPDLRGAGWSSAP
:: ** * : : .* : :.* * * * *
MAV_2202|M.avium_104 TRAGWGVERIARAWETLMLRLGYQRYGAQGGDWGAAVTTQIGR--NRGHC
MMAR_3314|M.marinum_M SSTGWGVDRIARAWETLMQNLGYQRYGAQGGDWGAAVTTQIGR--NGGRC
Mflv_0644|M.gilvum_PYR-GCK TNAGWGVGKIAQAWETLMLRLGYQRYGAQGGDWGAAITTQMGR--NRGHC
Mvan_0521|M.vanbaalenii_PYR-1 TNAGWGVGKIAQAWETLMLRLGYQRYGAQGGDWGAAITTQMGR--NRGHC
MSMEG_5658|M.smegmatis_MC2_155 TTTGWGIGRIAQAWDTLMTRLGYDRYGAQGGDWGAAVTTQIGR--NVGNC
TH_2132|M.thermoresistible__bu TTTGWGVGRIATXXX-----------------------------------
Mb1864c|M.bovis_AF2122/97 SGFGYQIDEHARVIGEFVDHLGLDRYLSMGQDWGGPISMAVAV--ERADR
Rv1833c|M.tuberculosis_H37Rv SGFGYQIDEHARVIGEFVDHLGLDRYLSMGQDWGGPISMAVAV--ERADR
MAB_4300|M.abscessus_ATCC_1997 VQYGYSVLDHADMHEALLSYLGIERFHLLTHDLGNSVGQEMLARFEFEQQ
MUL_4778|M.ulcerans_Agy99 RSR-YTKKEMADDLAGVLDRLGIASVRLVAHDWGGPVAFIMMLRYPAKVT
: *
MAV_2202|M.avium_104 VAIHLNMPIGRPGQEALTNPTEQERAALAALANHRK-------RGTGYSK
MMAR_3314|M.marinum_M VAIHLNMPIAMPTRTALTNPTAAEQEVLAALAYHRK-------WGTGYFK
Mflv_0644|M.gilvum_PYR-GCK AAIHLNMPIAYPPAGGITDPTEEEQLALAALTTYQR-------WETGYSE
Mvan_0521|M.vanbaalenii_PYR-1 AAIHLNMPIAYPPAGGITDPTEEEQLALAALTTYQR-------WETGYSE
MSMEG_5658|M.smegmatis_MC2_155 VGIHVNMPIARPPAEGVGEMTEEVRQALERMQYYRK-------WDSGYMK
TH_2132|M.thermoresistible__bu --------AARAPR-----PTS--------IRPWRR-------RCTG---
Mb1864c|M.bovis_AF2122/97 VRGVVLGNTWFWPADTLAMKAFSRVMSSPPVQYAIL-------RRNFFVE
Rv1833c|M.tuberculosis_H37Rv VRGVVLGNTWFWPADTLAMKAFSRVMSSPPVQYAIL-------RRNFFVE
MAB_4300|M.abscessus_ATCC_1997 SRGRVPIDSVTWLNGGLFIEAYRPRIAQTLMSRTPLGDLVSRFQGTPVTR
MUL_4778|M.ulcerans_Agy99 GFFGMNTAAPWFPRDLGMVRDIWRFWYQIPILLPVIG----PRVIADPKA
:
MAV_2202|M.avium_104 QQSTRPQTLGYGLADSPVGQLAWIVEKFWDWADCDGHPENA--LSRDELL
MMAR_3314|M.marinum_M QQSTRPQTVGYGLTDSPVGQLAWIVEKFWAWMDCAGNPENV--LTRDELL
Mflv_0644|M.gilvum_PYR-GCK QQSTRPQTVGYGLADSPVGQMAWIVEKFAAWMDCDGHPENV--LSRDELL
Mvan_0521|M.vanbaalenii_PYR-1 QQSTRPQTVGYGLADSPVGQMAWIVEKFAAWMDCDGHPENV--LSRDELL
MSMEG_5658|M.smegmatis_MC2_155 QQSTRPQTVGYGLVDSPVGQLAWIVEKFWSWMDCDGHPENV--LSRDELL
TH_2132|M.thermoresistible__bu --TTTP--------------------------------------------
Mb1864c|M.bovis_AF2122/97 R--LIPAGTEHRPSSAVMAHYRAVQPNAAARRGVAEMPKQI--LAARPLL
Rv1833c|M.tuberculosis_H37Rv R--LIPAGTEHRPSSAVMAHYRAVQPNAAARRGVAEMPKQI--LAARPLL
MAB_4300|M.abscessus_ATCC_1997 RIMDAAVSEMFGPDTKPSPRLLSLFQQVLEYNDGARVTHQVGRFINDRYD
MUL_4778|M.ulcerans_Agy99 RYFRVLTSWVGGGFTIADEDVRMYVERMRQPGHAVAGSRWYRTFQSSEAL
MAV_2202|M.avium_104 DNVMVYWVTNTAASSARLYWESFSAWGGGDRVELPTGVAAFPGELLKAPR
MMAR_3314|M.marinum_M DNVMMYWVNAAAASSARLYWESFKVWGQTERVELPTGVASFPKEVLRAPR
Mflv_0644|M.gilvum_PYR-GCK DNVMMYWATNSGSSSARLYWESFKTLDATTRVELPTGIAAFPKEVLRAPR
Mvan_0521|M.vanbaalenii_PYR-1 DNVMMYWATNSGSSSARLYWESFKTLDATTRVELPTGIAAFPKEVLRAPR
MSMEG_5658|M.smegmatis_MC2_155 DNVMLYWVTASAASSARLYWESYDTFAGGDFVTLPTGVASFPKEILRAPR
TH_2132|M.thermoresistible__bu --------------------------------------------------
Mb1864c|M.bovis_AF2122/97 ARLAREVPATLGTKPTLLIWG-MKDVAFRPKTIIPRLSATFPDHVL----
Rv1833c|M.tuberculosis_H37Rv ARLAREVPATLGTKPTLLIWG-MKDVAFRPKTIIPRLSATFPDHVL----
MAB_4300|M.abscessus_ATCC_1997 NRSRWVRAMRETAVPMRMIDGPIDPNSGLHMAERYLEVIHDPDVVLLD--
MUL_4778|M.ulcerans_Agy99 PWMRGEYADARVDVPVRWLHGTDDPVLTPQLLRGYEDHISDFEVEFVDG-
MAV_2202|M.avium_104 SWCEPAYNITHWTDMPRGGHFAAFEQPELFVEDLRVFFATVR-
MMAR_3314|M.marinum_M AWCEPNYNITHWTTMPRGGHFAAFEQPELFVGDVRAFFATVR-
Mflv_0644|M.gilvum_PYR-GCK SWCEPIYNITHWTTMPRGGHFAALEQPRLFVDDIRAFFESVR-
Mvan_0521|M.vanbaalenii_PYR-1 SWCEPIYNITHWTTMPRGGHFAALEQPRLFVDDIRAFFESVR-
MSMEG_5658|M.smegmatis_MC2_155 AWCEKAYNVTHFTMMPRGGHFAAFEQPELFVEDVAKFFDSVR-
TH_2132|M.thermoresistible__bu -------------------------------------------
Mb1864c|M.bovis_AF2122/97 ------------VELPNAKHFIQEDAPDRIAAAIIERFG----
Rv1833c|M.tuberculosis_H37Rv ------------VELPNAKHFIQEDAPDRIAAAIIERFG----
MAB_4300|M.abscessus_ATCC_1997 ---------------DNIGHWPQIEAPEAVLTHFLEHIDRITP
MUL_4778|M.ulcerans_Agy99 -----------------VGHWIVEQRPDLVLDRLRAFLRIET-