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RPFRIDVPDDVIDDLKARLTRTRWPEAECVDDWSQGIPLSYTRDLAAYWANEYDWRAREAALNRFDQFIT EIDGLDLHFIHQRSPHQDAFPLLITHGWPGSVVEFHKVIEPLTNPTAHGGRAEDAFHVVCPSLPGYGFSG KPSSTGWGVDRIARAWETLMQNLGYQRYGAQGGDWGAAVTTQIGRNGGRCVAIHLNMPIAMPTRTALTNP TAAEQEVLAALAYHRKWGTGYFKQQSTRPQTVGYGLTDSPVGQLAWIVEKFWAWMDCAGNPENVLTRDEL LDNVMMYWVNAAAASSARLYWESFKVWGQTERVELPTGVASFPKEVLRAPRAWCEPNYNITHWTTMPRGG HFAAFEQPELFVGDVRAFFATVR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3314 | - | - | 100% (374) | hydrolase |
| M. marinum M | MMAR_2710 | - | 5e-06 | 27.10% (107) | haloalkane dehalogenase |
| M. marinum M | MMAR_5114 | ephA | 2e-05 | 23.97% (146) | epoxide hydrolase EphA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1864c | - | 1e-07 | 30.11% (93) | haloalkane dehalogenase |
| M. gilvum PYR-GCK | Mflv_0644 | - | 0.0 | 77.81% (374) | epocide hydrolase domain-containing protein |
| M. tuberculosis H37Rv | Rv1833c | - | 1e-07 | 30.11% (93) | haloalkane dehalogenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0528c | - | 8e-05 | 21.74% (161) | epoxide hydrolase EphA |
| M. avium 104 | MAV_2202 | - | 0.0 | 82.35% (374) | epoxide hydrolase |
| M. smegmatis MC2 155 | MSMEG_5658 | - | 1e-168 | 72.46% (374) | epoxide hydrolase |
| M. thermoresistible (build 8) | TH_2132 | - | 1e-78 | 82.47% (154) | epoxide hydrolase 1 |
| M. ulcerans Agy99 | MUL_3052 | - | 2e-06 | 27.10% (107) | haloalkane dehalogenase |
| M. vanbaalenii PYR-1 | Mvan_0521 | - | 0.0 | 77.81% (374) | epocide hydrolase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3314|M.marinum_M ------MRPFRIDVPDDVIDDLKARLTRTRWPEAECVDDWSQGIPLSYTR
MAV_2202|M.avium_104 ------MKPFRIDVPDDVLDDLRARLARTRWPEAECVDDWSQGMPLAYTR
Mflv_0644|M.gilvum_PYR-GCK ---MRAVRPFSIHVADDVLDDLRTRLSRTRWPEAECVPDWTQGIPLGYTR
Mvan_0521|M.vanbaalenii_PYR-1 MSAVRAVRPFSIHVADDVLDDLRTRLSRTRWPEAECVPDWTQGIPLGYTR
MSMEG_5658|M.smegmatis_MC2_155 -MTDSLIRPFRIAVPDADLDDLKSRLSRTRWPEPETVDDWGQGIPLDYTR
TH_2132|M.thermoresistible__bu ---MPSVKPFRIAVPDDDLDDLRHRLARTRWPDRECVDDWGQGVPLDYVR
Mb1864c|M.bovis_AF2122/97 -------------------------------------------MSIDFT-
Rv1833c|M.tuberculosis_H37Rv -------------------------------------------MSIDFT-
MUL_3052|M.ulcerans_Agy99 ---------------------------------------MGRQFTPDFT-
MAB_0528c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3314|M.marinum_M DLAAYWANEYDWRAREAALNRFDQFITEIDGLDLHFIHQRSPHQDAFPLL
MAV_2202|M.avium_104 ELADYWANDYDWRAREAALNRFDQFVTEIDGLDIHFIHQRSPHADAFPLL
Mflv_0644|M.gilvum_PYR-GCK ELAAYWADGYDWRSREAALNRFDQFVVEIHGVDIHFIHQRSPHQEAFPLV
Mvan_0521|M.vanbaalenii_PYR-1 ELAAYWADGYDWRSREAALNRFDQFVVEIHGVDIHFIHQRSPHQEAFPLV
MSMEG_5658|M.smegmatis_MC2_155 ELAEYWANGYDWRAREQALNRFDHYVTELDGLDIHFIHQRCARPDAFPLL
TH_2132|M.thermoresistible__bu DLAGYWADGYDWRAREAALNRFDQFITELDGLDIHFIHQRSPHPDAFPLL
Mb1864c|M.bovis_AF2122/97 --------------PDPQLYPFESRWFDSSRGRIHYVDE----GTGPPIL
Rv1833c|M.tuberculosis_H37Rv --------------PDPQLYPFESRWFDSSRGRIHYVDE----GTGPPIL
MUL_3052|M.ulcerans_Agy99 --------------PDPKLYPFASRWFDSSRGRLHYIDE----SDGPPIL
MAB_0528c|M.abscessus_ATCC_199 --------------MTDAAVDIRERDIATNGVHLRIVEAG--EPGQPAVI
: :: :. .::
MMAR_3314|M.marinum_M ITHGWPGSVVEFHKVIEPLTNPTAHGGRAEDAFHVVCPSLPGYGFSGKPS
MAV_2202|M.avium_104 ITHGWPGSIVEFHKVIEPLTNPAS--GRGEDAFHVVCPSLPGYGFSGKPT
Mflv_0644|M.gilvum_PYR-GCK ITHGWPGSIVEFHNVIEPLTNPTAHGGRAEDAFHVVCPALPGYGFSGKPT
Mvan_0521|M.vanbaalenii_PYR-1 ITHGWPGSIVEFHNVIEPLTNPTAHGGRAEDAFHVVCPALPGYGFSGKPT
MSMEG_5658|M.smegmatis_MC2_155 LTHGWPGSIVEFHKVIEPLT---------EAGFDVVCPSLPGYGFSGKPT
TH_2132|M.thermoresistible__bu ITHGWPGSIVEFHKVIGPLTDPTAHGGTAADAFHVVCPSLPGYGFSGKPT
Mb1864c|M.bovis_AF2122/97 LCHGNPTWSFLYRDIIVALR----------DRFRCVAPDYLGFGLSERPS
Rv1833c|M.tuberculosis_H37Rv LCHGNPTWSFLYRDIIVALR----------DRFRCVAPDYLGFGLSERPS
MUL_3052|M.ulcerans_Agy99 LCHGNPTWSFLYRHIIVALR----------DHFRCIAPDYLGFGLSEHPG
MAB_0528c|M.abscessus_ATCC_199 LSHGFPELAYSWRHQIPALA---------AAGYHVIAPDQRGYGRSSMPA
: ** * ::. * .* : :.* *:* * *
MMAR_3314|M.marinum_M STG-WGVDRIARAWETLMQNLGYQRYGAQGGDWGAAVTTQIGRNGGRCVA
MAV_2202|M.avium_104 RAG-WGVERIARAWETLMLRLGYQRYGAQGGDWGAAVTTQIGRNRGHCVA
Mflv_0644|M.gilvum_PYR-GCK NAG-WGVGKIAQAWETLMLRLGYQRYGAQGGDWGAAITTQMGRNRGHCAA
Mvan_0521|M.vanbaalenii_PYR-1 NAG-WGVGKIAQAWETLMLRLGYQRYGAQGGDWGAAITTQMGRNRGHCAA
MSMEG_5658|M.smegmatis_MC2_155 TTG-WGIGRIAQAWDTLMTRLGYDRYGAQGGDWGAAVTTQIGRNVGNCVG
TH_2132|M.thermoresistible__bu TTG-WGVGRIATXXX-----------------------------------
Mb1864c|M.bovis_AF2122/97 GFG-YQIDEHARVIGEFVDHLGLDRYLSMGQDWGGPISMAVAVERADRVR
Rv1833c|M.tuberculosis_H37Rv GFG-YQIDEHARVIGEFVDHLGLDRYLSMGQDWGGPISMAVAVERADRVR
MUL_3052|M.ulcerans_Agy99 TFG-YKVDEHAQVVGEFVDHLGLDNYLTMGQDWGGPISMAVAVERAERVR
MAB_0528c|M.abscessus_ATCC_199 HIDDYNIEALSDDLLGILDDVGAGKATFVGHDWGAVVTWHTALAVPERVS
. : : :
MMAR_3314|M.marinum_M IHLNMPIAMPTRTALTNPTAAEQEVLAALAYHRKW-GTGYFKQQSTRPQT
MAV_2202|M.avium_104 IHLNMPIGRPGQEALTNPTEQERAALAALANHRKR-GTGYSKQQSTRPQT
Mflv_0644|M.gilvum_PYR-GCK IHLNMPIAYPPAGGITDPTEEEQLALAALTTYQRW-ETGYSEQQSTRPQT
Mvan_0521|M.vanbaalenii_PYR-1 IHLNMPIAYPPAGGITDPTEEEQLALAALTTYQRW-ETGYSEQQSTRPQT
MSMEG_5658|M.smegmatis_MC2_155 IHVNMPIARPPAEGVGEMTEEVRQALERMQYYRKW-DSGYMKQQSTRPQT
TH_2132|M.thermoresistible__bu ------AARAPR-----PTS--------IRPWRRR-CTG-----TTTP--
Mb1864c|M.bovis_AF2122/97 GVVLGNTWFWPADTLAMKAFSRVMSSPPVQYAILR-RNFFVER--LIPAG
Rv1833c|M.tuberculosis_H37Rv GVVLGNTWFWPADTLAMKAFSRVMSSPPVQYAILR-RNFFVER--LIPAG
MUL_3052|M.ulcerans_Agy99 GIVLGNTWFWPADTLTMKAFSTVMSSLPMQYAILH-HNFFVER--LIPAG
MAB_0528c|M.abscessus_ATCC_199 GVVGLSVPFTRRSQVPPTQAWNKLFGDNFFYILYFQEPGVADADLNRDPA
.
MMAR_3314|M.marinum_M VGYGLTDSPVGQLAWIVEKFWAWMDCAG-NPE-----NVLTRDELLDNVM
MAV_2202|M.avium_104 LGYGLADSPVGQLAWIVEKFWDWADCDG-HPE-----NALSRDELLDNVM
Mflv_0644|M.gilvum_PYR-GCK VGYGLADSPVGQMAWIVEKFAAWMDCDG-HPE-----NVLSRDELLDNVM
Mvan_0521|M.vanbaalenii_PYR-1 VGYGLADSPVGQMAWIVEKFAAWMDCDG-HPE-----NVLSRDELLDNVM
MSMEG_5658|M.smegmatis_MC2_155 VGYGLVDSPVGQLAWIVEKFWSWMDCDG-HPE-----NVLSRDELLDNVM
TH_2132|M.thermoresistible__bu --------------------------------------------------
Mb1864c|M.bovis_AF2122/97 TEHRPSSAVMAHYRAVQPNAAARRGVAE-MPK-----QILAARPLLARLA
Rv1833c|M.tuberculosis_H37Rv TEHRPSSAVMAHYRAVQPNAAARRGVAE-MPK-----QILAARPLLARLA
MUL_3052|M.ulcerans_Agy99 TTHRPSSAVMEHYRGVQPTASARVGVAE-MPK-----QILAARPLLARLA
MAB_0528c|M.abscessus_ATCC_199 TTMRRMMAGMARIDGATMIAPGPAGFVERMPDPGELPEWLSQDELDHYIT
MMAR_3314|M.marinum_M MYWVNAAAA-----SSARLYWESFKVWGQTERVELPTGVASFPKEVLRAP
MAV_2202|M.avium_104 VYWVTNTAA-----SSARLYWESFSAWGGGDRVELPTGVAAFPGELLKAP
Mflv_0644|M.gilvum_PYR-GCK MYWATNSGS-----SSARLYWESFKTLDATTRVELPTGIAAFPKEVLRAP
Mvan_0521|M.vanbaalenii_PYR-1 MYWATNSGS-----SSARLYWESFKTLDATTRVELPTGIAAFPKEVLRAP
MSMEG_5658|M.smegmatis_MC2_155 LYWVTASAA-----SSARLYWESYDTFAGGDFVTLPTGVASFPKEILRAP
TH_2132|M.thermoresistible__bu --------------------------------------------------
Mb1864c|M.bovis_AF2122/97 REVPATLGT-----KPTLLIWG-MKDVAFRPKTIIPRLSATFPDHVL---
Rv1833c|M.tuberculosis_H37Rv REVPATLGT-----KPTLLIWG-MKDVAFRPKTIIPRLSATFPDHVL---
MUL_3052|M.ulcerans_Agy99 SEVPAQLGT-----KPALLVWG-MKDFAFRPEPMLARMRAVFADHIL---
MAB_0528c|M.abscessus_ATCC_199 EFARTGFTGGLNWYRNFDRNWALTERLAGANVVVPSLFIAGAADPVLGFT
MMAR_3314|M.marinum_M RAWCEPNYNITHW--TTMPRGGHFAAFEQPELFVGDVRAFFATVR-
MAV_2202|M.avium_104 RSWCEPAYNITHW--TDMPRGGHFAAFEQPELFVEDLRVFFATVR-
Mflv_0644|M.gilvum_PYR-GCK RSWCEPIYNITHW--TTMPRGGHFAALEQPRLFVDDIRAFFESVR-
Mvan_0521|M.vanbaalenii_PYR-1 RSWCEPIYNITHW--TTMPRGGHFAALEQPRLFVDDIRAFFESVR-
MSMEG_5658|M.smegmatis_MC2_155 RAWCEKAYNVTHF--TMMPRGGHFAAFEQPELFVEDVAKFFDSVR-
TH_2132|M.thermoresistible__bu ----------------------------------------------
Mb1864c|M.bovis_AF2122/97 ---------------VELPNAKHFIQEDAPDRIAAAIIERFG----
Rv1833c|M.tuberculosis_H37Rv ---------------VELPNAKHFIQEDAPDRIAAAIIERFG----
MUL_3052|M.ulcerans_Agy99 ---------------VELPEAKHLIQEDAPDEIAAAIIARFG----
MAB_0528c|M.abscessus_ATCC_199 DHAGSAKYRTDNRGDLLIDGAGHWIQQERPLEVNAALLAFLREVVH