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TELHLAVALDGYGWHPQAWRYAFAHNATGGGQFSGRYWAALARTAERGLLDFLTIDDSLDAQPGRRAEIS PRRLVGRADATLVAARVAPVTEHIGLIPVATVTHTEPFHVSKAIATLDHISHGRAGWQVRVSATEQEAAL FGRRAVPGVDELFDEAADAVEVARRLWDSWEDDAVIRDVATGRYIDRDKLHYIDFAGKYFSVKGPSITPR PPQGQPVVAALAHTPPVYEFAAANADLVFVTPREDDSLRAILAEVDRARRAAGRAIRVYADLVVSLVGHP LAAAAAISSDARVFAGSATDLAELVVAWQDAGVDGVRLRPAVNALDLPAIVDDLVPRLQRAGRFRTGYRD GETLRERLGLAPAPNRYATAAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2050 | - | - | 100% (373) | fmnh2-utilizing oxygenase |
| M. avium 104 | MAV_0340 | - | 5e-37 | 34.54% (304) | nitrilotriacetate monooxygenase component A |
| M. avium 104 | MAV_3809 | - | 2e-35 | 34.13% (252) | dibenzothiophene desulfurization enzyme A |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0415 | fgd1 | 7e-05 | 25.42% (240) | F420-dependent glucose-6-phosphate dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0216 | - | 9e-92 | 52.38% (357) | fmnh2-utilizing oxygenase |
| M. tuberculosis H37Rv | Rv0407 | fgd1 | 7e-05 | 25.42% (240) | F420-dependent glucose-6-phosphate dehydrogenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4234c | - | 1e-108 | 57.97% (364) | putative FMNH2-utilizing oxygenase |
| M. marinum M | MMAR_0701 | - | 1e-147 | 70.70% (372) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_2177 | - | 1e-100 | 53.39% (384) | fmnh2-utilizing oxygenase |
| M. thermoresistible (build 8) | TH_4079 | - | 3e-41 | 39.47% (228) | PUTATIVE nitrilotriacetate monooxygenase component A |
| M. ulcerans Agy99 | MUL_1043 | - | 1e-11 | 27.39% (314) | hypothetical protein MUL_1043 |
| M. vanbaalenii PYR-1 | Mvan_6020 | - | 1e-37 | 28.22% (443) | xenobiotic compound DszA family monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2050|M.avium_104 ------MT-ELHLAVALDGYGWHPQAWRYAFAHNATGGGQFSGRYWAALA
MMAR_0701|M.marinum_M ------MTRPLHLGVALDGYGWHPQAWQTTLAADAQTRSVLSGDYWADLA
Mflv_0216|M.gilvum_PYR-GCK ------MSGAPHVAVALEGYGWHPQAWR----HSAGAPPVTSGGYWAELV
MAB_4234c|M.abscessus_ATCC_199 --MGVAPTVTTLLGLALDGHGWHPDADK-------HAGKPLTGRYWTQQV
MSMEG_2177|M.smegmatis_MC2_155 MATPSDPAHLPRLAVALDGTGWHPASWR---EPDARPAEVLRAGYWTDLI
TH_4079|M.thermoresistible__bu -----------LPETRLSG--------------------ITDIDHYLELA
Mvan_6020|M.vanbaalenii_PYR-1 ---------MMHLITWLMGNSYHAAGWR---HQLAWERTAMRLDVLIEIA
Mb0415|M.bovis_AF2122/97 ---------MAELKLGYKAS-----------------AEQFAPRELVELA
Rv0407|M.tuberculosis_H37Rv ---------MAELKLGYKAS-----------------AEQFAPRELVELA
MUL_1043|M.ulcerans_Agy99 ----------------MHSHPYHP--------------ELASGAGVAAVA
.
MAV_2050|M.avium_104 RTAERGLLDFLTIDDSLDAQPGR----RAEISPRRLVGRADATLVAARVA
MMAR_0701|M.marinum_M ITAERGLLDFLTIDDTLMPQPGR----RERIDPKRLAGRADAVLVAARIA
Mflv_0216|M.gilvum_PYR-GCK ATAERGLLDFVTFDDAPAPQRRR----RPEIDPRWLAGRPDAVLVAARVA
MAB_4234c|M.abscessus_ATCC_199 QLAEQGLLDFVTFEDSFAPTPG---------------GRLDAVLTAGRVA
MSMEG_2177|M.smegmatis_MC2_155 GAAEHGLIDFVTIEDGLTLQSDHPF--RPDDRTDRLRGRLDAVLIASRVA
TH_4079|M.thermoresistible__bu RIAERGKLDAIFFADHPVLKGKTEFRPFDA---------LDPVTLVTALS
Mvan_6020|M.vanbaalenii_PYR-1 KIAEEAKLDALFVADGNGVRNMDKVGLFEANTPSARPTVYDPVTLMAAIS
Mb0415|M.bovis_AF2122/97 VAAEAHGMDSATVSDHFQPWRHQG----------GHAPFSLSWMTAVGER
Rv0407|M.tuberculosis_H37Rv VAAEAHGMDSATVSDHFQPWRHQG----------GHAPFSLSWMTAVGER
MUL_1043|M.ulcerans_Agy99 AAAERAGFHGFGFTDHPAPSQRWL--------EAGGHDSLDPFVALGFAA
** :. . * .
MAV_2050|M.avium_104 PVTEHIGLIP-VATVTHTEPFHVSKAIATLDHISHGRAGWQVRVSATEQE
MMAR_0701|M.marinum_M PLTRHIGLIP-VATVTHTEPFHISKAIATLDYVSHGRAGWQARVSATTHE
Mflv_0216|M.gilvum_PYR-GCK PLTRHIGLIR-VATTTHTEPAALSESLATLDHLSQGRAGWQVRISASRHE
MAB_4234c|M.abscessus_ATCC_199 PATHHIGLIP-TAPATHNEPFHLSKSIATLDIVSGGRAGWQVTIADTEDE
MSMEG_2177|M.smegmatis_MC2_155 PTTRHIGLIP-TAVTTFTEPFHISKAVATLDYVSTGRAGVRVQVSSRRDA
TH_4079|M.thermoresistible__bu TATTHIGLVA-TASTTYTEPYGLARRFATLDHVSRGRAGWNIVTTANAAA
Mvan_6020|M.vanbaalenii_PYR-1 QHTKHIGLVG-TASTTYESPWVVARRFASLDHLSNGRASWNVVTGSNPGD
Mb0415|M.bovis_AF2122/97 TNRLLLGTSV-LTPTFRYNPAVIAQAFATMGCLYPNRVFLGVGTGEALNE
Rv0407|M.tuberculosis_H37Rv TNRLLLGTSV-LTPTFRYNPAVIAQAFATMGCLYPNRVFLGVGTGEALNE
MUL_1043|M.ulcerans_Agy99 AQTTSLRLIPNIVVLPYRNPFVVAKSAATLDLLSGGRFILAVGVGYLKRE
: . .* ::. *::. : .*
MAV_2050|M.avium_104 AALFGRRAVP-----GVDELFDEAADAVEVARRLWDSWEDDAVIRDVATG
MMAR_0701|M.marinum_M AALFGRRIVRR--GESSAEAFGEARDFVEVVRKLWDSWEDDAVIRDVTTG
Mflv_0216|M.gilvum_PYR-GCK AQLFGRRDPD-----DLGDLFAHARGVVEIVRTRWEGGG-----------
MAB_4234c|M.abscessus_ATCC_199 ADAFGRTKVL-----PLQDLLDEAADSVEVVRRLWDSWEDDAEIRDVATG
MSMEG_2177|M.smegmatis_MC2_155 AAHFGRRQFPDDRAALVAELFGEATDYVEVLRRLWDSWEDDAEIRDVSTG
TH_4079|M.thermoresistible__bu AANFGRPAHP-----DPEHRYSRADEFLQVALRLWDSWEDDAIVGDKQAP
Mvan_6020|M.vanbaalenii_PYR-1 SENFGLAHHP-----DRDSRYARAEEFVSACKALWNSWDEDAFVERKDTG
Mb0415|M.bovis_AF2122/97 IATGYEGAWP-----EFKERFARLRESVGLMRQLWSGDR-----------
Rv0407|M.tuberculosis_H37Rv IATGYEGAWP-----EFKERFARLRESVGLMRQLWSGDR-----------
MUL_1043|M.ulcerans_Agy99 FAALG---------VDHAERAELFDEALQVIRAVWTSDD-----------
: * .
MAV_2050|M.avium_104 RYIDRDKLHYIDFAGKYFSVKGPSITPRPPQ-GQPVVAALAHTPPVYEFA
MMAR_0701|M.marinum_M RYIDRDKVHYIDFVGTYFSVKGPSITPRPPQ-GQPVVAALAHAGPIYEFA
Mflv_0216|M.gilvum_PYR-GCK --------------------------------GRPVVTALAHTPTVYEFA
MAB_4234c|M.abscessus_ATCC_199 RFIDRDKLHYIDFEGRFFSVKGPSITPRSPQ-GQAVVAALARSRPGQAFA
MSMEG_2177|M.smegmatis_MC2_155 RFIDRDKLHYIDFVGAHFSVKGPSITPRPPQ-GQPVVAALGHVDAAYRLI
TH_4079|M.thermoresistible__bu RFVDPDKIHAIDHRGEHFSVAGPLEVPRSPQ-GHPVLFQAGSSEPGKQLA
Mvan_6020|M.vanbaalenii_PYR-1 QYLNARKVRVPDYKGRHLSVKGPLNVSRSPQ-GRPVLFHAGQSEGGRRLA
Mb0415|M.bovis_AF2122/97 ----------VDFDGDYYRLKGASIYDVPDG-GVPVYIAAG-GPAVAKYA
Rv0407|M.tuberculosis_H37Rv ----------VDFDGDYYRLKGASIYDVPDG-GVPVYIAAG-GPAVAKYA
MUL_1043|M.ulcerans_Agy99 ----------ISFEGRHFSARGITAHPRPASNPYPPIWVGGNTAAARRRV
. .
MAV_2050|M.avium_104 AANADLVFVTPREDD--SLRAILAEVDRA---RRAAGRAIRVYADLVVSL
MMAR_0701|M.marinum_M AASADVVFITPTDED--SLRSILGEV-------RATGVALKVFADVVVSL
Mflv_0216|M.gilvum_PYR-GCK ADSADLVFVTPRDDE--SLSTILAEVR------EAGGHELRVYADLYVTF
MAB_4234c|M.abscessus_ATCC_199 AKNADLIFVTPHDGA--SAAEIPARLHN-----TAGHRVIKVLADLVVSF
MSMEG_2177|M.smegmatis_MC2_155 ATSADVGFITPHSTQ--EVTSLVETIAGH---RPADTEPVRVFADVVVFL
TH_4079|M.thermoresistible__bu AKYAEAIFTAQPTVE--EARQFYADVKARVRQHGRDPDRVHILPGLSAII
Mvan_6020|M.vanbaalenii_PYR-1 ARHADCIFEAAASVE--AAREFYADLKRRRVEIGGEPDHLRIIVSVAVYL
Mb0415|M.bovis_AF2122/97 GRAGDGFICTSGKGEELYTEKLMPAVREGAAAADRSVDGIDKMIEIKISY
Rv0407|M.tuberculosis_H37Rv GRAGDGFICTSGKGEELYTEKLMPAVREGAAAADRSVDGIDKMIEIKISY
MUL_1043|M.ulcerans_Agy99 AVHGDGWCPFPAPAP-LAQTAGTAAIDS----ADRLAAGIDDLRRKCDAA
. .: : :
MAV_2050|M.avium_104 VGHPL-----------AAAAAISSD-------------------------
MMAR_0701|M.marinum_M HDG----------------ADFRSD-------------------------
Mflv_0216|M.gilvum_PYR-GCK TGV----------------VDERSD-------------------------
MAB_4234c|M.abscessus_ATCC_199 DRE----------------DEFPSD-------------------------
MSMEG_2177|M.smegmatis_MC2_155 DDTAAGAQARRDRLDEVAGSEYVSD-------------------------
TH_4079|M.thermoresistible__bu GGTEEEARRIQRRLEDLTVPDYGLEQLSRIVGYRVGRDDLDRRLQFGSDD
Mvan_6020|M.vanbaalenii_PYR-1 GRTESEAVELYSELNSLISPDLGVDFLAKAVSEDLTGYPVDGPMPDLS--
Mb0415|M.bovis_AF2122/97 DPD----------------PELALN-------------------------
Rv0407|M.tuberculosis_H37Rv DPD----------------PELALN-------------------------
MUL_1043|M.ulcerans_Agy99 GRD---------------FSAIDVT-------------------------
MAV_2050|M.avium_104 ------------------------------------ARVFAGSATDLAEL
MMAR_0701|M.marinum_M ------------------------------------ALVWAGSPTELVEM
Mflv_0216|M.gilvum_PYR-GCK ------------------------------------ARVFSGTADELADT
MAB_4234c|M.abscessus_ATCC_199 ------------------------------------AAVFTGRAPELAEL
MSMEG_2177|M.smegmatis_MC2_155 ------------------------------------AEIFAGTPAQLADL
TH_4079|M.thermoresistible__bu PPAIHMQSRYALVRRLVSTENLTVRELLLRLSGGRGHRVFAGTPEQVADT
Mvan_6020|M.vanbaalenii_PYR-1 APVVGGNSIRGQLDAIAKAEQLTVRQMYERVVPTMGNTALIGTATQIADV
Mb0415|M.bovis_AF2122/97 --------------------------------NTRFWAPLSLTAEQKHSI
Rv0407|M.tuberculosis_H37Rv --------------------------------NTRFWAPLSLTAEQKHSI
MUL_1043|M.ulcerans_Agy99 ------------------------------------FTNFDGGGPASADF
.
MAV_2050|M.avium_104 VVAWQDAG-VDGVRLRPAVNALDLPAIVDDLVPRLQRAGRFRT----GYR
MMAR_0701|M.marinum_M LLDWRRLG-IDGARLRPAVNATDLAGIVDEVVPLLQRAGCFRT----GYR
Mflv_0216|M.gilvum_PYR-GCK IAGWHRHG-VHGVRLRPAVNAVDLPVIADEVIPLLQCRTGFRS----TYR
MAB_4234c|M.abscessus_ATCC_199 IAQWHEWG-IDGVRLRPAANALDIPVVVDELVPLLQAHQGFRT----EYE
MSMEG_2177|M.smegmatis_MC2_155 VQQWHAAG-ASGLRLRPATLPHDLRQITDGLVPELQRRGAFRD----GYD
TH_4079|M.thermoresistible__bu IEEWFTTGAADGFNLIPPALPSSLTAFVDHVVPELQRRGLFRT----EYT
Mvan_6020|M.vanbaalenii_PYR-1 MEEWYTTGACDGFVLGASISPFTLLLIRDELVPELQRRGLFRR----HYT
Mb0415|M.bovis_AF2122/97 DDPIEMEKAADALPIEQIAKRWIVASDPDEAVEKVGQYVTWGLNHLVFHA
Rv0407|M.tuberculosis_H37Rv DDPIEMEKAADALPIEQIAKRWIVASDPDEAVEKVGQYVTWGLNHLVFHA
MUL_1043|M.ulcerans_Agy99 NADAYLGGLEKLAMLGVTWVHVGLPG--DGLAHALECIDRFRV-------
: : * : :
MAV_2050|M.avium_104 DGETLRERLGLAPAPNRYATAAS-----
MMAR_0701|M.marinum_M DGETLRERLGLPPAPNRYAAVSR-----
Mflv_0216|M.gilvum_PYR-GCK PGETLRGRLGIES---------------
MAB_4234c|M.abscessus_ATCC_199 NG-ALRERLGLPAAINRYARKSA-----
MSMEG_2177|M.smegmatis_MC2_155 TT-TLRGLLGLPRPANRYAAA-------
TH_4079|M.thermoresistible__bu GT-TLRDHLGLPRPRNRFTTGRPVAAAS
Mvan_6020|M.vanbaalenii_PYR-1 GS-TLRENLGLPPVDN-----SPFAT--
Mb0415|M.bovis_AF2122/97 PGHDQRRFLELFQSDLAPRLRRLG----
Rv0407|M.tuberculosis_H37Rv PGHDQRRFLELFQSDLAPRLRRLG----
MUL_1043|M.ulcerans_Agy99 ------QVIEAA----------------
: