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GVAPTVTTLLGLALDGHGWHPDADKHAGKPLTGRYWTQQVQLAEQGLLDFVTFEDSFAPTPGGRLDAVLT AGRVAPATHHIGLIPTAPATHNEPFHLSKSIATLDIVSGGRAGWQVTIADTEDEADAFGRTKVLPLQDLL DEAADSVEVVRRLWDSWEDDAEIRDVATGRFIDRDKLHYIDFEGRFFSVKGPSITPRSPQGQAVVAALAR SRPGQAFAAKNADLIFVTPHDGASAAEIPARLHNTAGHRVIKVLADLVVSFDREDEFPSDAAVFTGRAPE LAELIAQWHEWGIDGVRLRPAANALDIPVVVDELVPLLQAHQGFRTEYENGALRERLGLPAAINRYARKS A*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4234c | - | - | 100% (352) | putative FMNH2-utilizing oxygenase |
| M. abscessus ATCC 19977 | MAB_4125 | - | 6e-26 | 34.68% (173) | putative nitrilotriacetate monooxygenase |
| M. abscessus ATCC 19977 | MAB_3401 | - | 1e-25 | 33.18% (223) | putative monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0216 | - | 6e-66 | 44.06% (345) | fmnh2-utilizing oxygenase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0701 | - | 1e-100 | 54.82% (363) | oxidoreductase |
| M. avium 104 | MAV_2050 | - | 1e-108 | 57.97% (364) | fmnh2-utilizing oxygenase |
| M. smegmatis MC2 155 | MSMEG_2177 | - | 8e-89 | 49.61% (381) | fmnh2-utilizing oxygenase |
| M. thermoresistible (build 8) | TH_4079 | - | 2e-35 | 41.00% (200) | PUTATIVE nitrilotriacetate monooxygenase component A |
| M. ulcerans Agy99 | MUL_1043 | - | 2e-09 | 26.56% (320) | hypothetical protein MUL_1043 |
| M. vanbaalenii PYR-1 | Mvan_6020 | - | 3e-25 | 33.51% (188) | xenobiotic compound DszA family monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_4079|M.thermoresistible__bu -----------LPETRLSG--------------------ITDIDHYLELA
Mvan_6020|M.vanbaalenii_PYR-1 ---------MMHLITWLMGNSYHAAGWR---HQLAWERTAMRLDVLIEIA
MMAR_0701|M.marinum_M ------MTRPLHLGVALDGYGWHPQAWQTTLAADAQTRSVLSGDYWADLA
MAV_2050|M.avium_104 ------MT-ELHLAVALDGYGWHPQAWRYAFAHNATGGGQFSGRYWAALA
Mflv_0216|M.gilvum_PYR-GCK ------MSGAPHVAVALEGYGWHPQAWR----HSAGAPPVTSGGYWAELV
MAB_4234c|M.abscessus_ATCC_199 --MGVAPTVTTLLGLALDGHGWHPDADK-------HAGKPLTGRYWTQQV
MSMEG_2177|M.smegmatis_MC2_155 MATPSDPAHLPRLAVALDGTGWHPASWR---EPDARPAEVLRAGYWTDLI
MUL_1043|M.ulcerans_Agy99 ----------------MHSHPYHP--------------ELASGAGVAAVA
: .
TH_4079|M.thermoresistible__bu RIAERGKLDAIFFADHPVLKGKTEFRPFDA---------LDPVTLVTALS
Mvan_6020|M.vanbaalenii_PYR-1 KIAEEAKLDALFVADGNGVRNMDKVGLFEANTPSARPTVYDPVTLMAAIS
MMAR_0701|M.marinum_M ITAERGLLDFLTIDDTLMPQPGR----RERIDPKRLAGRADAVLVAARIA
MAV_2050|M.avium_104 RTAERGLLDFLTIDDSLDAQPGR----RAEISPRRLVGRADATLVAARVA
Mflv_0216|M.gilvum_PYR-GCK ATAERGLLDFVTFDDAPAPQRRR----RPEIDPRWLAGRPDAVLVAARVA
MAB_4234c|M.abscessus_ATCC_199 QLAEQGLLDFVTFEDSFAPTPG---------------GRLDAVLTAGRVA
MSMEG_2177|M.smegmatis_MC2_155 GAAEHGLIDFVTIEDGLTLQSDHPF--RPDDRTDRLRGRLDAVLIASRVA
MUL_1043|M.ulcerans_Agy99 AAAERAGFHGFGFTDHPAPSQR--------WLEAGGHDSLDPFVALGFAA
**.. :. . . * *. :
TH_4079|M.thermoresistible__bu TATTHIGLVA-TASTTYTEPYGLARRFATLDHVSRGRAGWNIVTTANAAA
Mvan_6020|M.vanbaalenii_PYR-1 QHTKHIGLVG-TASTTYESPWVVARRFASLDHLSNGRASWNVVTGSNPGD
MMAR_0701|M.marinum_M PLTRHIGLIP-VATVTHTEPFHISKAIATLDYVSHGRAGWQARVSATTHE
MAV_2050|M.avium_104 PVTEHIGLIP-VATVTHTEPFHVSKAIATLDHISHGRAGWQVRVSATEQE
Mflv_0216|M.gilvum_PYR-GCK PLTRHIGLIR-VATTTHTEPAALSESLATLDHLSQGRAGWQVRISASRHE
MAB_4234c|M.abscessus_ATCC_199 PATHHIGLIP-TAPATHNEPFHLSKSIATLDIVSGGRAGWQVTIADTEDE
MSMEG_2177|M.smegmatis_MC2_155 PTTRHIGLIP-TAVTTFTEPFHISKAVATLDYVSTGRAGVRVQVSSRRDA
MUL_1043|M.ulcerans_Agy99 AQTTSLRLIPNIVVLPYRNPFVVAKSAATLDLLSGGRFILAVGVGYLKRE
* : *: . .. .* ::. *:** :* **
TH_4079|M.thermoresistible__bu AANFGRPAHP-----DPEHRYSRADEFLQVALRLWDSWEDDAIVGDKQAP
Mvan_6020|M.vanbaalenii_PYR-1 SENFGLAHHP-----DRDSRYARAEEFVSACKALWNSWDEDAFVERKDTG
MMAR_0701|M.marinum_M AALFGRRIVRR--GESSAEAFGEARDFVEVVRKLWDSWEDDAVIRDVTTG
MAV_2050|M.avium_104 AALFGRRAVP-----GVDELFDEAADAVEVARRLWDSWEDDAVIRDVATG
Mflv_0216|M.gilvum_PYR-GCK AQLFGRRDPD-----DLGDLFAHARGVVEIVRTRWEGGG-----------
MAB_4234c|M.abscessus_ATCC_199 ADAFGRTKVL-----PLQDLLDEAADSVEVVRRLWDSWEDDAEIRDVATG
MSMEG_2177|M.smegmatis_MC2_155 AAHFGRRQFPDDRAALVAELFGEATDYVEVLRRLWDSWEDDAEIRDVSTG
MUL_1043|M.ulcerans_Agy99 FAALG---------VDHAERAELFDEALQVIRAVWTSDD-----------
:* :. * .
TH_4079|M.thermoresistible__bu RFVDPDKIHAIDHRGEHFSVAGPLEVPRSPQ-GHPVLFQAGSSEPGKQLA
Mvan_6020|M.vanbaalenii_PYR-1 QYLNARKVRVPDYKGRHLSVKGPLNVSRSPQ-GRPVLFHAGQSEGGRRLA
MMAR_0701|M.marinum_M RYIDRDKVHYIDFVGTYFSVKGPSITPRPPQ-GQPVVAALAHAGPIYEFA
MAV_2050|M.avium_104 RYIDRDKLHYIDFAGKYFSVKGPSITPRPPQ-GQPVVAALAHTPPVYEFA
Mflv_0216|M.gilvum_PYR-GCK --------------------------------GRPVVTALAHTPTVYEFA
MAB_4234c|M.abscessus_ATCC_199 RFIDRDKLHYIDFEGRFFSVKGPSITPRSPQ-GQAVVAALARSRPGQAFA
MSMEG_2177|M.smegmatis_MC2_155 RFIDRDKLHYIDFVGAHFSVKGPSITPRPPQ-GQPVVAALGHVDAAYRLI
MUL_1043|M.ulcerans_Agy99 ----------ISFEGRHFSARGITAHPRPASNPYPPIWVGGNTAAARRRV
. : .
TH_4079|M.thermoresistible__bu AKYAEAIFTAQPTVEEARQFYADVKARVRQHGRDPDRVHILPGLSAIIGG
Mvan_6020|M.vanbaalenii_PYR-1 ARHADCIFEAAASVEAAREFYADLKRRRVEIGGEPDHLRIIVSVAVYLGR
MMAR_0701|M.marinum_M AASADVVFITPTDEDSLRSILGEV-------RATGVALKVFADVVVSLHD
MAV_2050|M.avium_104 AANADLVFVTPREDDSLRAILAEVDRA---RRAAGRAIRVYADLVVSLVG
Mflv_0216|M.gilvum_PYR-GCK ADSADLVFVTPRDDESLSTILAEVR------EAGGHELRVYADLYVTFTG
MAB_4234c|M.abscessus_ATCC_199 AKNADLIFVTPHDGASAAEIPARLHN-----TAGHRVIKVLADLVVSFDR
MSMEG_2177|M.smegmatis_MC2_155 ATSADVGFITPHSTQEVTSLVETIAGH---RPADTEPVRVFADVVVFLDD
MUL_1043|M.ulcerans_Agy99 AVHGDGWCPFPAPAPLAQTAGTAAIDSADRLAAGIDDLRRKCDAAGRDFS
* .: :: .
TH_4079|M.thermoresistible__bu TEEEARRIQRRLEDLTVPDYGLEQLSRIVGYRVGRDDLDRRLQFGSDDPP
Mvan_6020|M.vanbaalenii_PYR-1 TESEAVELYSELNSLISPDLGVDFLAKAVSEDLTGYPVDGPMPDLS--AP
MMAR_0701|M.marinum_M G----------------ADFRSD---------------------------
MAV_2050|M.avium_104 HPL-----------AAAAAISSD---------------------------
Mflv_0216|M.gilvum_PYR-GCK V----------------VDERSD---------------------------
MAB_4234c|M.abscessus_ATCC_199 E----------------DEFPSD---------------------------
MSMEG_2177|M.smegmatis_MC2_155 TAAGAQARRDRLDEVAGSEYVSD---------------------------
MUL_1043|M.ulcerans_Agy99 A----------------IDVTFTN--------------------------
TH_4079|M.thermoresistible__bu AIHMQSRYALVRRLVSTENLTVRELLLRLSGGRGHRVFAGTPEQVADTIE
Mvan_6020|M.vanbaalenii_PYR-1 VVGGNSIRGQLDAIAKAEQLTVRQMYERVVPTMGNTALIGTATQIADVME
MMAR_0701|M.marinum_M ----------------------------------ALVWAGSPTELVEMLL
MAV_2050|M.avium_104 ----------------------------------ARVFAGSATDLAELVV
Mflv_0216|M.gilvum_PYR-GCK ----------------------------------ARVFSGTADELADTIA
MAB_4234c|M.abscessus_ATCC_199 ----------------------------------AAVFTGRAPELAELIA
MSMEG_2177|M.smegmatis_MC2_155 ----------------------------------AEIFAGTPAQLADLVQ
MUL_1043|M.ulcerans_Agy99 -------------------------------------FDGGGPASADFNA
* .:
TH_4079|M.thermoresistible__bu EWFTTGAADGFNLIPPALPSSLTAFVDHVVPELQRRGLFRTEYTGT-TLR
Mvan_6020|M.vanbaalenii_PYR-1 EWYTTGACDGFVLGASISPFTLLLIRDELVPELQRRGLFRRHYTGS-TLR
MMAR_0701|M.marinum_M DWRRLG-IDGARLRPAVNATDLAGIVDEVVPLLQRAGCFRTGYRDGETLR
MAV_2050|M.avium_104 AWQDAG-VDGVRLRPAVNALDLPAIVDDLVPRLQRAGRFRTGYRDGETLR
Mflv_0216|M.gilvum_PYR-GCK GWHRHG-VHGVRLRPAVNAVDLPVIADEVIPLLQCRTGFRSTYRPGETLR
MAB_4234c|M.abscessus_ATCC_199 QWHEWG-IDGVRLRPAANALDIPVVVDELVPLLQAHQGFRTEYENG-ALR
MSMEG_2177|M.smegmatis_MC2_155 QWHAAG-ASGLRLRPATLPHDLRQITDGLVPELQRRGAFRDGYDTT-TLR
MUL_1043|M.ulcerans_Agy99 DAYLGGLEKLAMLGVTWVHVGLP--GDGLAHALECIDRFRVQVIEAA---
* * . : * : *: **
TH_4079|M.thermoresistible__bu DHLGLPRPRNRFTTGRPVAAAS
Mvan_6020|M.vanbaalenii_PYR-1 ENLGLPPVDN-----SPFAT--
MMAR_0701|M.marinum_M ERLGLPPAPNRYAAVSR-----
MAV_2050|M.avium_104 ERLGLAPAPNRYATAAS-----
Mflv_0216|M.gilvum_PYR-GCK GRLGIES---------------
MAB_4234c|M.abscessus_ATCC_199 ERLGLPAAINRYARKSA-----
MSMEG_2177|M.smegmatis_MC2_155 GLLGLPRPANRYAAA-------
MUL_1043|M.ulcerans_Agy99 ----------------------