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VAELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPWRHQGGHAPFSLSWMTAVGERTNRLLL GTSVLTPTFRYNPAVIAQAFATMGCLYPNRVFLGVGTGEALNEIATGYEGAWPEFKERFARLRESVGLMR QLWSGDRVDFDGDYYRLKGASIYDVPDGGVPVYIAAGGPAVAKYAGRAGDGFICTSGKGEELYTEKLMPA VREGAAAADRSVDGIDKMIEIKISYDPDPELALNNTRFWAPLSLTAEQKHSIDDPIEMEKAADALPIEQI AKRWIVASDPDEAVEKVGQYVTWGLNHLVFHAPGHDQRRFLELFQSDLAPRLRRLG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0407 | fgd1 | - | 100% (336) | PROBABLE F420-DEPENDENT GLUCOSE-6-PHOSPHATE DEHYDROGENASE FGD1 |
| M. tuberculosis H37Rv | Rv0132c | fgd2 | 8e-53 | 36.28% (328) | putative f420-dependent glucose-6-phosphate dehydrogenase |
| M. tuberculosis H37Rv | Rv0791c | - | 3e-16 | 23.85% (348) | hypothetical protein Rv0791c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0415 | fgd1 | 0.0 | 100.00% (336) | F420-dependent glucose-6-phosphate dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0211 | - | 1e-175 | 86.61% (336) | luciferase family protein |
| M. leprae Br4923 | MLBr_00269 | - | 0.0 | 88.99% (336) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4230c | - | 1e-171 | 85.03% (334) | F420-dependent glucose-6-phosphate dehydrogenase |
| M. marinum M | MMAR_0709 | fgd1 | 0.0 | 90.48% (336) | F420-dependent glucose-6-phosphate dehydrogenase Fgd1 |
| M. avium 104 | MAV_4761 | - | 0.0 | 90.48% (336) | F420-dependent glucose-6-phosphate dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0777 | - | 1e-179 | 89.55% (335) | F420-dependent glucose-6-phosphate dehydrogenase |
| M. thermoresistible (build 8) | TH_2304 | - | 1e-178 | 88.69% (336) | PROBABLE F420-DEPENDENT GLUCOSE-6-PHOSPHATE DEHYDROGENASE FGD1 |
| M. ulcerans Agy99 | MUL_2814 | fgd1 | 0.0 | 89.88% (336) | F420-dependent glucose-6-phosphate dehydrogenase Fgd1 |
| M. vanbaalenii PYR-1 | Mvan_0698 | - | 1e-175 | 87.20% (336) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0211|M.gilvum_PYR-GCK MA-ELKLGYKASAEQFAPRELVELAVAAEEHGMDSATVSDHFQPWRHEGG
Mvan_0698|M.vanbaalenii_PYR-1 MA-ELKLGYKASAEQFAPRELVELAVAAEEHGMDSATVSDHFQPWRHEGG
MAB_4230c|M.abscessus_ATCC_199 MARELKLGYKASAEQFAPRELVELAVATESHGFDSATVSDHFQPWRYNGG
MSMEG_0777|M.smegmatis_MC2_155 MVAELKLGYKASAEQFAPRELVELAVLAESAGMDSATVSDHFQPWRHEGG
TH_2304|M.thermoresistible__bu -VAELKLGYKASAEQFAPRELVELGVAAEEHGMDSATVSDHFQPWRHKGG
Rv0407|M.tuberculosis_H37Rv -MAELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPWRHQGG
Mb0415|M.bovis_AF2122/97 -MAELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPWRHQGG
MLBr_00269|M.leprae_Br4923 -MAELRLGYKASAEQFAPRELVELGVAAEAHGMDSATVSDHFQPWRHQGG
MMAR_0709|M.marinum_M -MAELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPWRHEGG
MUL_2814|M.ulcerans_Agy99 -MAELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPWRHEGG
MAV_4761|M.avium_104 -MAELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPWRHEGG
**:******************.* :* *:*************::**
Mflv_0211|M.gilvum_PYR-GCK HAPFSLAWMTAVGERTTRLQLGTSVLTPTFRYNPAVIAQAFATMGCLYPD
Mvan_0698|M.vanbaalenii_PYR-1 HAPFSLAWMTAVGERTKRLQLGTSVLTPTFRYNPAVIAQAFATMGCLYPG
MAB_4230c|M.abscessus_ATCC_199 HAPFSLAWMTAVGERTQRLQLGTSVLTPTFRYNPAVTAQAFATMGCLYPG
MSMEG_0777|M.smegmatis_MC2_155 HAPFSLAWMTAVGERTKNLVLGTSVLTPTFRYNPAVIAQAFATMGCLYPG
TH_2304|M.thermoresistible__bu HAPFSLAWMTAVGERTKRITLGTSVLTPTFRYNPAVIAQAFATMACLYPD
Rv0407|M.tuberculosis_H37Rv HAPFSLSWMTAVGERTNRLLLGTSVLTPTFRYNPAVIAQAFATMGCLYPN
Mb0415|M.bovis_AF2122/97 HAPFSLSWMTAVGERTNRLLLGTSVLTPTFRYNPAVIAQAFATMGCLYPN
MLBr_00269|M.leprae_Br4923 HASFSLSWMTAVGERTNRILLGTSVLTPTFRYNPAVIGQAFATMGCLYPN
MMAR_0709|M.marinum_M HAPFSLAWMTAVGERTKRMQLGTSVLTPTFRYNPAVIAQAFATMGCLYPN
MUL_2814|M.ulcerans_Agy99 HAPFSLAWMTAVGERTKRMQLGTSVLTPTFRYNPAVIAQAFATMGCLYPN
MAV_4761|M.avium_104 HAPFSLAWMTAVGERTTRITLGTSVLTPTFRYNPAVVAQAFATMACLYPG
**.***:********* .: **************** .******.****.
Mflv_0211|M.gilvum_PYR-GCK RIFLGVGTGEALNEIATGYEGEWPEFKERYARLRESVRLMRELWLGDRVD
Mvan_0698|M.vanbaalenii_PYR-1 RIFLGVGTGEALNEIATGYEGDWPEFKERYARLRESVRLMRDLWLGDRVD
MAB_4230c|M.abscessus_ATCC_199 RIFLGVGTGEALNEIATGYIGEWPEFKERFARLRESVRLMRELWTGERVD
MSMEG_0777|M.smegmatis_MC2_155 RIFLGVGTGEALNEIATGYAGEWPEFKERFARLRESVRLMRELWLGDRVD
TH_2304|M.thermoresistible__bu RIFLGVGTGEALNEIATGYEGEWPEFKERFARLREAVRLMRELWLGDRVD
Rv0407|M.tuberculosis_H37Rv RVFLGVGTGEALNEIATGYEGAWPEFKERFARLRESVGLMRQLWSGDRVD
Mb0415|M.bovis_AF2122/97 RVFLGVGTGEALNEIATGYEGAWPEFKERFARLRESVGLMRQLWSGDRVD
MLBr_00269|M.leprae_Br4923 RVFLGVGTGEALNEVATGYQGAWPEFKERFARLRESVRLMRELWRGDRVD
MMAR_0709|M.marinum_M RIFLGVGTGEALNEVATGYQGVWPEFKERFARLRESVRLMRELWRGDRVD
MUL_2814|M.ulcerans_Agy99 RIFLGVGTGEALNEVATGYQGVWPEFKERFARLRESVRLMRELWRGDRVD
MAV_4761|M.avium_104 RIFLGVGTGEALNEIATGYQGEWPEFKERFARLRESVRLMRELWRGDRVD
*:************:**** * *******:*****:* ***:** *:***
Mflv_0211|M.gilvum_PYR-GCK FEGEYYKTKGASIYDVPEGGIPIYIAAGGPQVAKYAGRAGDGFICTSGKG
Mvan_0698|M.vanbaalenii_PYR-1 FEGEYYKTKGASIYDVPEGGIPIYIAAGGPQVAKYAGRAGDGFICTSGKG
MAB_4230c|M.abscessus_ATCC_199 FEGEYYRTQGAAIYDVPEGGIPVYIAAGGAVVAKYAGRAGDGFICTSGKG
MSMEG_0777|M.smegmatis_MC2_155 FDGEYYRTKGASIYDVPEGGIPVYIAAGGPVVAKYAGRAGDGFICTSGKG
TH_2304|M.thermoresistible__bu FDGEYYRTKGASIYDVPEGGVPVYIAAGGPVVAKYAGRAGDGFICTSGKG
Rv0407|M.tuberculosis_H37Rv FDGDYYRLKGASIYDVPDGGVPVYIAAGGPAVAKYAGRAGDGFICTSGKG
Mb0415|M.bovis_AF2122/97 FDGDYYRLKGASIYDVPDGGVPVYIAAGGPAVAKYAGRAGDGFICTSGKG
MLBr_00269|M.leprae_Br4923 FDGDYYQLKGASIYDVPEGGVPIYIAAGGPEVAKYAGRAGEGFVCTSGKG
MMAR_0709|M.marinum_M FDGEYYRLRGASIYDVPEGGVPVYIAAGGPAVAKYAGRAGDGFICTSGKG
MUL_2814|M.ulcerans_Agy99 FDGEYYRLRGASIYDVPEGGVPVYTAAGGPAVAKYAGRAGDGFICTSGKG
MAV_4761|M.avium_104 FDGEYYRLKGASIYDVPDGGVPIYIAAGGPAVAKYAGRAGDGFICTSGKG
*:*:**: :**:*****:**:*:* ****. *********:**:******
Mflv_0211|M.gilvum_PYR-GCK EELYKEKLIPAMREGAEAAGKNPDDVDRMIEIKISYDTDPELALENTRFW
Mvan_0698|M.vanbaalenii_PYR-1 EELYKDKLIPAMREGAEAAGKNPDDIDRMIEIKISYDTDPELALENTRFW
MAB_4230c|M.abscessus_ATCC_199 EELYSGKLIPAVREGAALAERSFDDIDRMIEIKISYDPDPDKALENTRFW
MSMEG_0777|M.smegmatis_MC2_155 EELYAEKLIPAVKEGAAAADRDADAIDRMIEIKISYDTDPELALENTRFW
TH_2304|M.thermoresistible__bu AELYQDKLIPAVAEGAAAAGRDADEIDKMIEIKISYDPDPELALENTRFW
Rv0407|M.tuberculosis_H37Rv EELYTEKLMPAVREGAAAADRSVDGIDKMIEIKISYDPDPELALNNTRFW
Mb0415|M.bovis_AF2122/97 EELYTEKLMPAVREGAAAADRSVDGIDKMIEIKISYDPDPELALNNTRFW
MLBr_00269|M.leprae_Br4923 EELYTEKLIPAVLEGAAVAGRDADDIDKMIEIKMSYDPDPEQALSNIRFW
MMAR_0709|M.marinum_M EELYSEKLMPAVREGAAINNRNIDDIDKMIEIKISYDPDPELALNNTRFW
MUL_2814|M.ulcerans_Agy99 EDLYSEKLMPAVREGAAINNRNIDDIDKMIEIKISYDPDPELALNNTRFW
MAV_4761|M.avium_104 EELYKDKLIPAVKEGAAINDRNVDDIDKMIEIKISYDPDPELALENTRFW
:** **:**: *** :. * :*:*****:***.**: **.* ***
Mflv_0211|M.gilvum_PYR-GCK APLSLTAEQKHSIDDPMEMEKAADELPIEQVAKRWIVASDPDEAVAKVAD
Mvan_0698|M.vanbaalenii_PYR-1 APLSLTAEQKHSIDDPIEMEKAADALPIEQVAKRWIVASDPDEAVAKVKD
MAB_4230c|M.abscessus_ATCC_199 APLSLTPEQKHSIHDPIEMERAADELPIEQVAKRWIVASDPDEAVEKVAD
MSMEG_0777|M.smegmatis_MC2_155 APLSLTAEQKHSIDDPIEMEKAADALPIEQVAKRWIVASDPDEAVEKVGQ
TH_2304|M.thermoresistible__bu APLSLTAEQKHSIDDPIEMERAADELPIEQVAKRWIVASDPDEAVEQVAQ
Rv0407|M.tuberculosis_H37Rv APLSLTAEQKHSIDDPIEMEKAADALPIEQIAKRWIVASDPDEAVEKVGQ
Mb0415|M.bovis_AF2122/97 APLSLTAEQKHSIDDPIEMEKAADALPIEQIAKRWIVASDPDEAVEKVGQ
MLBr_00269|M.leprae_Br4923 APLSLAAEQKHSIDDPIEMEKVADALPIEQVAKRWIVVSDPDEAVARVGQ
MMAR_0709|M.marinum_M APLSLSAEQKRSIGDPIEMEAAAEALPIEQIAKRWIVASDPDEAVEKVGQ
MUL_2814|M.ulcerans_Agy99 APLSLSAEQKRSIGDPIEMEAAAEALPIEQIAKRWIVASDPDEAVEKVGQ
MAV_4761|M.avium_104 APLSLTAEQKHSIDDPIEMEKAADALPIEQVAKRWIVASDPDEAVAKVKD
*****:.***:** **:*** .*: *****:******.******* :* :
Mflv_0211|M.gilvum_PYR-GCK YVDYGLNHLVFHAPGHDQRRFLELFQRDLEPRLRKLG
Mvan_0698|M.vanbaalenii_PYR-1 YVDWGLNHLVFHAPGHDQRRFLELFRRDLEPRLRKLG
MAB_4230c|M.abscessus_ATCC_199 YVGWGLNHLVFHAPGHDQKRFLELFKTDLEPRLRKLG
MSMEG_0777|M.smegmatis_MC2_155 YVKWGLNHLVFHAPGHDQRRFLELFKRDLEPRLRKLA
TH_2304|M.thermoresistible__bu YVKWGLNHLVFHAPGHDQRRFLELFRTDLEPRLRRLG
Rv0407|M.tuberculosis_H37Rv YVTWGLNHLVFHAPGHDQRRFLELFQSDLAPRLRRLG
Mb0415|M.bovis_AF2122/97 YVTWGLNHLVFHAPGHDQRRFLELFQSDLAPRLRRLG
MLBr_00269|M.leprae_Br4923 YVTWGLNHLVFHAPGHNQRRFLELFEKDLAPRLRRLG
MMAR_0709|M.marinum_M YVAWGLNHLVLHAPGHDQLRFLELFEKDLAPRLRRLG
MUL_2814|M.ulcerans_Agy99 YVAWGLNHLVLHAPGHDQLRFLELFEKDLAPRLRRLG
MAV_4761|M.avium_104 YVDWGLNHLVFHAPGHDQRRFLELFEKDLAPRLRRLG
** :******:*****:* ******. ** ****:*.