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MTRPLHLGVALDGYGWHPQAWQTTLAADAQTRSVLSGDYWADLAITAERGLLDFLTIDDTLMPQPGRRER IDPKRLAGRADAVLVAARIAPLTRHIGLIPVATVTHTEPFHISKAIATLDYVSHGRAGWQARVSATTHEA ALFGRRIVRRGESSAEAFGEARDFVEVVRKLWDSWEDDAVIRDVTTGRYIDRDKVHYIDFVGTYFSVKGP SITPRPPQGQPVVAALAHAGPIYEFAAASADVVFITPTDEDSLRSILGEVRATGVALKVFADVVVSLHDG ADFRSDALVWAGSPTELVEMLLDWRRLGIDGARLRPAVNATDLAGIVDEVVPLLQRAGCFRTGYRDGETL RERLGLPPAPNRYAAVSR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0701 | - | - | 100% (368) | oxidoreductase |
| M. marinum M | MMAR_0703 | - | 1e-32 | 32.88% (292) | FMNH2-utilizing oxygenase |
| M. marinum M | MMAR_0393 | - | 3e-06 | 26.27% (316) | hypothetical protein MMAR_0393 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0978c | - | 3e-06 | 26.77% (198) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_0216 | - | 4e-88 | 50.85% (352) | fmnh2-utilizing oxygenase |
| M. tuberculosis H37Rv | Rv0953c | - | 3e-06 | 26.77% (198) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4234c | - | 1e-100 | 54.82% (363) | putative FMNH2-utilizing oxygenase |
| M. avium 104 | MAV_2050 | - | 1e-147 | 70.70% (372) | fmnh2-utilizing oxygenase |
| M. smegmatis MC2 155 | MSMEG_2177 | - | 1e-104 | 55.09% (383) | fmnh2-utilizing oxygenase |
| M. thermoresistible (build 8) | TH_4079 | - | 2e-36 | 37.33% (225) | PUTATIVE nitrilotriacetate monooxygenase component A |
| M. ulcerans Agy99 | MUL_1043 | - | 5e-06 | 25.86% (321) | hypothetical protein MUL_1043 |
| M. vanbaalenii PYR-1 | Mvan_6020 | - | 1e-28 | 28.84% (267) | xenobiotic compound DszA family monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0701|M.marinum_M ------MTRPLHLGVALDGYGWHPQAWQTTLAADAQTRSVLSGDYWADLA
MAV_2050|M.avium_104 ------MT-ELHLAVALDGYGWHPQAWRYAFAHNATGGGQFSGRYWAALA
Mflv_0216|M.gilvum_PYR-GCK ------MSGAPHVAVALEGYGWHPQAWR----HSAGAPPVTSGGYWAELV
MAB_4234c|M.abscessus_ATCC_199 --MGVAPTVTTLLGLALDGHGWHPDADK-------HAGKPLTGRYWTQQV
MSMEG_2177|M.smegmatis_MC2_155 MATPSDPAHLPRLAVALDGTGWHPASWR---EPDARPAEVLRAGYWTDLI
TH_4079|M.thermoresistible__bu -----------LPETRLSG--------------------ITDIDHYLELA
Mvan_6020|M.vanbaalenii_PYR-1 ---------MMHLITWLMGNSYHAAGWR---HQLAWERTAMRLDVLIEIA
Mb0978c|M.bovis_AF2122/97 --------MHYGLVLFTSDRGITPAAAAR-----LAESHGFRTFYVPEHT
Rv0953c|M.tuberculosis_H37Rv --------MHYGLVLFTSDRGITPAAAAR-----LAESHGFRTFYVPEHT
MUL_1043|M.ulcerans_Agy99 ----------------MHSHPYHPELASG--------AGVAAVAAAAERA
.
MMAR_0701|M.marinum_M ITAERGLLDFLTIDDTLMPQPGR----RERIDPKRLAGRADAVLVAARIA
MAV_2050|M.avium_104 RTAERGLLDFLTIDDSLDAQPGR----RAEISPRRLVGRADATLVAARVA
Mflv_0216|M.gilvum_PYR-GCK ATAERGLLDFVTFDDAPAPQRRR----RPEIDPRWLAGRPDAVLVAARVA
MAB_4234c|M.abscessus_ATCC_199 QLAEQGLLDFVTFEDSFAPTPG---------------GRLDAVLTAGRVA
MSMEG_2177|M.smegmatis_MC2_155 GAAEHGLIDFVTIEDGLTLQSDHPF--RPDDRTDRLRGRLDAVLIASRVA
TH_4079|M.thermoresistible__bu RIAERGKLDAIFFADHPVLKGKTEFRPFDA---------LDPVTLVTALS
Mvan_6020|M.vanbaalenii_PYR-1 KIAEEAKLDALFVADGNGVRNMDKVGLFEANTPSARPTVYDPVTLMAAIS
Mb0978c|M.bovis_AF2122/97 HIPVKRQAAHPTTGDASLPDDRYMR-------------TLDPWVSLGAAS
Rv0953c|M.tuberculosis_H37Rv HIPVKRQAAHPTTGDASLPDDRYMR-------------TLDPWVSLGAAS
MUL_1043|M.ulcerans_Agy99 GFHGFGFTDHPAPSQRWLEAGGHDS--------------LDPFVALGFAA
: *. :
MMAR_0701|M.marinum_M PLTRHIGLIP-VATVTHTEPFHISKAIATLDYVSHGRAGWQARVSATTHE
MAV_2050|M.avium_104 PVTEHIGLIP-VATVTHTEPFHVSKAIATLDHISHGRAGWQVRVSATEQE
Mflv_0216|M.gilvum_PYR-GCK PLTRHIGLIR-VATTTHTEPAALSESLATLDHLSQGRAGWQVRISASRHE
MAB_4234c|M.abscessus_ATCC_199 PATHHIGLIP-TAPATHNEPFHLSKSIATLDIVSGGRAGWQVTIADTEDE
MSMEG_2177|M.smegmatis_MC2_155 PTTRHIGLIP-TAVTTFTEPFHISKAVATLDYVSTGRAGVRVQVSSRRDA
TH_4079|M.thermoresistible__bu TATTHIGLVA-TASTTYTEPYGLARRFATLDHVSRGRAGWNIVTTANAAA
Mvan_6020|M.vanbaalenii_PYR-1 QHTKHIGLVG-TASTTYESPWVVARRFASLDHLSNGRASWNVVTGSNPGD
Mb0978c|M.bovis_AF2122/97 AVTSRIRLATAVALPVEHDPITLAKSIATLDHLSHGRVSVGVGFGWNTDE
Rv0953c|M.tuberculosis_H37Rv AVTSRIRLATAVALPVEHDPITLAKSIATLDHLSHGRVSVGVGFGWNTDE
MUL_1043|M.ulcerans_Agy99 AQTTSLRLIPNIVVLPYRNPFVVAKSAATLDLLSGGRFILAVGVGYLKRE
* : * . .* ::. *:** :* **
MMAR_0701|M.marinum_M AALFGRRIVRR--GESSAEAFGEARDFVEVVRKLWDSWEDDAVIRDVTTG
MAV_2050|M.avium_104 AALFGRRAVP-----GVDELFDEAADAVEVARRLWDSWEDDAVIRDVATG
Mflv_0216|M.gilvum_PYR-GCK AQLFGRRDPD-----DLGDLFAHARGVVEIVRTRWEGGG-----------
MAB_4234c|M.abscessus_ATCC_199 ADAFGRTKVL-----PLQDLLDEAADSVEVVRRLWDSWEDDAEIRDVATG
MSMEG_2177|M.smegmatis_MC2_155 AAHFGRRQFPDDRAALVAELFGEATDYVEVLRRLWDSWEDDAEIRDVSTG
TH_4079|M.thermoresistible__bu AANFGRPAHP-----DPEHRYSRADEFLQVALRLWDSWEDDAIVGDKQAP
Mvan_6020|M.vanbaalenii_PYR-1 SENFGLAHHP-----DRDSRYARAEEFVSACKALWNSWDEDAFVERKDTG
Mb0978c|M.bovis_AF2122/97 LVDHGVPPGR---------RRTMLREYLEAMRALWTQEEAC---------
Rv0953c|M.tuberculosis_H37Rv LVDHGVPPGR---------RRTMLREYLEAMRALWTQEEAC---------
MUL_1043|M.ulcerans_Agy99 FAALGVDHAER---------AELFDEALQVIRAVWTSDDIS---------
* :. *
MMAR_0701|M.marinum_M RYIDRDKVHYIDFVGTYFSVKGPSITPRPPQ-GQPVVAALAHAGPIYEFA
MAV_2050|M.avium_104 RYIDRDKLHYIDFAGKYFSVKGPSITPRPPQ-GQPVVAALAHTPPVYEFA
Mflv_0216|M.gilvum_PYR-GCK --------------------------------GRPVVTALAHTPTVYEFA
MAB_4234c|M.abscessus_ATCC_199 RFIDRDKLHYIDFEGRFFSVKGPSITPRSPQ-GQAVVAALARSRPGQAFA
MSMEG_2177|M.smegmatis_MC2_155 RFIDRDKLHYIDFVGAHFSVKGPSITPRPPQ-GQPVVAALGHVDAAYRLI
TH_4079|M.thermoresistible__bu RFVDPDKIHAIDHRGEHFSVAGPLEVPRSPQ-GHPVLFQAGSSEPGKQLA
Mvan_6020|M.vanbaalenii_PYR-1 QYLNARKVRVPDYKGRHLSVKGPLNVSRSPQ-GRPVLFHAGQSEGGRRLA
Mb0978c|M.bovis_AF2122/97 ------------YDGEFVKFGPSWAWPKPVQPHIPVLVGAAGTEKNFKWI
Rv0953c|M.tuberculosis_H37Rv ------------YDGEFVKFGPSWAWPKPVQPHIPVLVGAAGTEKNFKWI
MUL_1043|M.ulcerans_Agy99 ------------FEGRHFSARGITAHPRPASNPYPPIWVGGNTAAARRRV
. : .
MMAR_0701|M.marinum_M AASADVVFITPTDEDSLRSILGEV-------RATGVALKVFADVVVSLHD
MAV_2050|M.avium_104 AANADLVFVTPREDDSLRAILAEVDRA---RRAAGRAIRVYADLVVSLVG
Mflv_0216|M.gilvum_PYR-GCK ADSADLVFVTPRDDESLSTILAEVR------EAGGHELRVYADLYVTFTG
MAB_4234c|M.abscessus_ATCC_199 AKNADLIFVTPHDGASAAEIPARLHN-----TAGHRVIKVLADLVVSFDR
MSMEG_2177|M.smegmatis_MC2_155 ATSADVGFITPHSTQEVTSLVETIAGH---RPADTEPVRVFADVVVFLDD
TH_4079|M.thermoresistible__bu AKYAEAIFTAQPTVEEARQFYADVKARVRQHGRDPDRVHILPGLSAIIGG
Mvan_6020|M.vanbaalenii_PYR-1 ARHADCIFEAAASVEAAREFYADLKRRRVEIGGEPDHLRIIVSVAVYLGR
Mb0978c|M.bovis_AF2122/97 ARSADGWITTPRDVD------------------IDEPVKLLQDIWAAAGR
Rv0953c|M.tuberculosis_H37Rv ARSADGWITTPRDVD------------------IDEPVKLLQDIWAAAGR
MUL_1043|M.ulcerans_Agy99 AVHGDGWCPFPAPAPLAQT-------------AGTAAIDSADRLAAGIDD
* .: : : .
MMAR_0701|M.marinum_M G----------------ADFRSD---------------------------
MAV_2050|M.avium_104 HPL-----------AAAAAISSD---------------------------
Mflv_0216|M.gilvum_PYR-GCK V----------------VDERSD---------------------------
MAB_4234c|M.abscessus_ATCC_199 E----------------DEFPSD---------------------------
MSMEG_2177|M.smegmatis_MC2_155 TAAGAQARRDRLDEVAGSEYVSD---------------------------
TH_4079|M.thermoresistible__bu TEEEARRIQRRLEDLTVPDYGLEQLSRIVGYRVGRDDLDRRLQFGSDDPP
Mvan_6020|M.vanbaalenii_PYR-1 TESEAVELYSELNSLISPDLGVDFLAKAVSEDLTGYPVDGPMPDLS--AP
Mb0978c|M.bovis_AF2122/97 DG------------------------------------------------
Rv0953c|M.tuberculosis_H37Rv DG------------------------------------------------
MUL_1043|M.ulcerans_Agy99 LR------------------------------------------------
MMAR_0701|M.marinum_M ----------------------------------ALVWAGSPTELVEMLL
MAV_2050|M.avium_104 ----------------------------------ARVFAGSATDLAELVV
Mflv_0216|M.gilvum_PYR-GCK ----------------------------------ARVFSGTADELADTIA
MAB_4234c|M.abscessus_ATCC_199 ----------------------------------AAVFTGRAPELAELIA
MSMEG_2177|M.smegmatis_MC2_155 ----------------------------------AEIFAGTPAQLADLVQ
TH_4079|M.thermoresistible__bu AIHMQSRYALVRRLVSTENLTVRELLLRLSGGRGHRVFAGTPEQVADTIE
Mvan_6020|M.vanbaalenii_PYR-1 VVGGNSIRGQLDAIAKAEQLTVRQMYERVVPTMGNTALIGTATQIADVME
Mb0978c|M.bovis_AF2122/97 ---------------------------------LPQIVALDVKPVPDKLA
Rv0953c|M.tuberculosis_H37Rv ---------------------------------LPQIVALDVKPVPDKLA
MUL_1043|M.ulcerans_Agy99 -----------------------------------RKCDAAGRDFSAIDV
.
MMAR_0701|M.marinum_M DWRRLG-IDGARLRPAVNATDLAGIVDEVVPLLQRAGCFRTGYRDGETLR
MAV_2050|M.avium_104 AWQDAG-VDGVRLRPAVNALDLPAIVDDLVPRLQRAGRFRTGYRDGETLR
Mflv_0216|M.gilvum_PYR-GCK GWHRHG-VHGVRLRPAVNAVDLPVIADEVIPLLQCRTGFRSTYRPGETLR
MAB_4234c|M.abscessus_ATCC_199 QWHEWG-IDGVRLRPAANALDIPVVVDELVPLLQAHQGFRTEYENG-ALR
MSMEG_2177|M.smegmatis_MC2_155 QWHAAG-ASGLRLRPATLPHDLRQITDGLVPELQRRGAFRDGYDTT-TLR
TH_4079|M.thermoresistible__bu EWFTTGAADGFNLIPPALPSSLTAFVDHVVPELQRRGLFRTEYTGT-TLR
Mvan_6020|M.vanbaalenii_PYR-1 EWYTTGACDGFVLGASISPFTLLLIRDELVPELQRRGLFRRHYTGS-TLR
Mb0978c|M.bovis_AF2122/97 RWAELGVTEVLFGMPDRSADDAAAYVERLAAKLACCV-------------
Rv0953c|M.tuberculosis_H37Rv RWAELGVTEVLFGMPDRSADDAAAYVERLAAKLACCV-------------
MUL_1043|M.ulcerans_Agy99 TFTNFD-----GGGPASADFNADAYLGGLEKLAMLGVTWVHVGLPGDGLA
: . . :
MMAR_0701|M.marinum_M ERLGLPPAPNRYAAVSR-----
MAV_2050|M.avium_104 ERLGLAPAPNRYATAAS-----
Mflv_0216|M.gilvum_PYR-GCK GRLGIES---------------
MAB_4234c|M.abscessus_ATCC_199 ERLGLPAAINRYARKSA-----
MSMEG_2177|M.smegmatis_MC2_155 GLLGLPRPANRYAAA-------
TH_4079|M.thermoresistible__bu DHLGLPRPRNRFTTGRPVAAAS
Mvan_6020|M.vanbaalenii_PYR-1 ENLGLPPVDN-----SPFAT--
Mb0978c|M.bovis_AF2122/97 ----------------------
Rv0953c|M.tuberculosis_H37Rv ----------------------
MUL_1043|M.ulcerans_Agy99 HALECIDRFRVQVIEAA-----