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RTARLLAVLAALLTVGLSAGLLAPPAGAQPPLRLSDYLTDTAGVLSDSGRKAITTAVDKLYTDRHIRLWV VYVDTFSGQTATRWAQDTLRTSDLGDYDALLAVATTDRAYAFLVPPTIRGVNQSRVDALRHNKIEPALHD GDWSGAAVAAATGLDTAPGSSGRVILLATLAALLVAVMGLLLVMRYRGRRRRAAALAAARRLDPTDLDAL AALPLPTLDDLSRALVVDVDNALRTSANELDLAVAEFGDQRTQPFTQAVTNAKAALSQAFTVRQQLDDGM PETPAQRRELLTQVIVSAARADRELESQTEAFEGLRDLVINAPSRLDGLTQQYVELTARIGPAEQQLAAL HNEFSAAALTSVSGNVTAAKERLAFADRNIGTARELAGQAVSGQQGRLVDAVRAAESALGQARSLLDAVD HAAGDIRHAIDQLPSAMADIENDIKRAAELLAATRDTKSGHAAELAAARDAATRAVEGARAGAPDDPLGA FGQLTKADAGLNAVLAAVAQERAAAERLARSLEQALFTAQSRVRAVSDYIDTRRGSIGPEARTRLAEAQR HLHAAADRRATDPADAIAHANAASTLAAEAQSLANGDVQAARRAYPRGGGGDMGAMLGGIIIGDLLSSGM RGGFGGWSPASFGGSTSSSGGGVLGGGGRF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2041 | - | - | 100% (661) | hypothetical protein MAV_2041 |
| M. avium 104 | MAV_2102 | - | 4e-40 | 44.88% (205) | hypothetical protein MAV_2102 |
| M. avium 104 | MAV_1428 | - | 6e-09 | 25.05% (479) | hypothetical protein MAV_1428 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2374 | - | 0.0 | 69.17% (665) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_2720 | - | 0.0 | 57.16% (670) | hypothetical protein Mflv_2720 |
| M. tuberculosis H37Rv | Rv2345 | - | 0.0 | 69.17% (665) | transmembrane protein |
| M. leprae Br4923 | MLBr_01629 | smc | 3e-05 | 27.34% (256) | putative cell division protein |
| M. abscessus ATCC 19977 | MAB_1706c | - | 1e-166 | 50.15% (676) | hypothetical protein MAB_1706c |
| M. marinum M | MMAR_3652 | - | 0.0 | 69.32% (665) | hypothetical protein MMAR_3652 |
| M. smegmatis MC2 155 | MSMEG_4484 | - | 0.0 | 58.06% (689) | putative transmembrane protein |
| M. thermoresistible (build 8) | TH_1853 | - | 3e-05 | 25.18% (421) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1450 | - | 4e-05 | 25.75% (233) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_3816 | - | 0.0 | 57.34% (668) | hypothetical protein Mvan_3816 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2720|M.gilvum_PYR-GCK -------MRVARLLP-LLLALLTVGL---LGAPAASAEPPLRLPTYLTDR
Mvan_3816|M.vanbaalenii_PYR-1 ----MAVMRVARLLP-MLLAVLTLGL---LCAPGVAAEPPLRLPTYLTDN
MSMEG_4484|M.smegmatis_MC2_155 -------MRIGRLFS-LLLAILTTGL---LVAPAAAAEPPLRLATQITDQ
Mb2374|M.bovis_AF2122/97 -------MRLVRLLG-MVLTILAAGL---LLGPPAGAQPPFRLSNYVTDN
Rv2345|M.tuberculosis_H37Rv -------MRLVRLLG-MVLTILAAGL---LLGPPAGAQPPFRLSNYVTDN
MMAR_3652|M.marinum_M -------MRIPRLLG-VILMIFTTGL---LLAPPSGAQPPFRLASYVTDN
MAV_2041|M.avium_104 -------MRTARLLA-VLAALLTVGLSAGLLAPPAGAQPPLRLSDYLTDT
MAB_1706c|M.abscessus_ATCC_199 -------MRLLRALAGLLGVLIAVCAPTLLLAPVASADPPFRIPGYVTDR
MLBr_01629|M.leprae_Br4923 MYLKSLTLKGFKSFASPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE
TH_1853|M.thermoresistible__bu MRLHRLALTNYRGIARREVEFPDRGVVVVSGANEIGKSSMIEALDLLFHA
MUL_1450|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2720|M.gilvum_PYR-GCK AGALDAAG------------------ESEVQTAIDQLYDDKRIRLWVVYV
Mvan_3816|M.vanbaalenii_PYR-1 AGALDTAG------------------TAEVQAAIDRLYNEERIRLWVVFV
MSMEG_4484|M.smegmatis_MC2_155 AGALSASQ------------------AASVQRALDRLYDDRRIKLWVVFV
Mb2374|M.bovis_AF2122/97 AGVLTSSG------------------RTAVTAAVDRLYADRRIRLWVVYV
Rv2345|M.tuberculosis_H37Rv AGVLTSSG------------------RTAVTAAVDRLYADRRIRLWVVYV
MMAR_3652|M.marinum_M ADALTSSG------------------RAKVTTAVNQLYTERHVRLWVVYV
MAV_2041|M.avium_104 AGVLSDSG------------------RKAITTAVDKLYTDRHIRLWVVYV
MAB_1706c|M.abscessus_ATCC_199 AGALKNP--------------------AKVRAAVDQLYDQQHVRLWVVYV
MLBr_01629|M.leprae_Br4923 QGAKTLRGSKMEDVIFAGTLSRAPLGRAEVTLIIDNSDNVLPIEYSEVSI
TH_1853|M.thermoresistible__bu KDRSTKKEVK-------------QVKPTHADVGAEITAEISTGPYRFVYH
MUL_1450|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2720|M.gilvum_PYR-GCK EDFSGQSAQTWAQTTFTRSDLGD---QDVILAVATVDRAYALITP-RGG-
Mvan_3816|M.vanbaalenii_PYR-1 DDFSGQDAQTWTQTTFARSDLGN---QDVILAVATVDRAYALIAP-KGG-
MSMEG_4484|M.smegmatis_MC2_155 EDFSGQNYIGWAQNTMRLSDFGD---DDALLAVATVDRAFAFQVP-DTL-
Mb2374|M.bovis_AF2122/97 ENFSGQSALNWAQRTTRTSELGN---YDALLAVATTGREYAFLVP-SAMP
Rv2345|M.tuberculosis_H37Rv ENFSGQSALNWAQRTTRTSELGN---YDALLAVATTGREYAFLVP-SAMP
MMAR_3652|M.marinum_M DDFSGQSATNWAQRTMQTSELGD---YDAILAVATVARSYAFLVP-STVD
MAV_2041|M.avium_104 DTFSGQTATRWAQDTLRTSDLGD---YDALLAVATTDRAYAFLVP-PTIR
MAB_1706c|M.abscessus_ATCC_199 KDFEGTDPTAWADKTIKASNLGD---RDALLAVATEERSYAFQVA-SGIK
MLBr_01629|M.leprae_Br4923 TRRMFRDGASEYEINGSSCRLMD---VQELLSDSGIGREMHVIVGQGKLD
TH_1853|M.thermoresistible__bu KRFHKKCATQLTILAPRREELSGDEAHERALAMLSETVDMELWRTQRVLQ
MUL_1450|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2720|M.gilvum_PYR-GCK -AVRADIDEVR------------TQQVEPRLRAGDWAGAAVAAAQGL---
Mvan_3816|M.vanbaalenii_PYR-1 -AVRVDIDKVR------------TQQVEPLLRTGDWAGAAVAAAEGL---
MSMEG_4484|M.smegmatis_MC2_155 -VDTARADDIR------------RNSIGPSLRREDWAGAAIAAADQLNTE
Mb2374|M.bovis_AF2122/97 GVSEGQVDNVR------------RYQIEPALHDGDYSGAAVAAANGLN--
Rv2345|M.tuberculosis_H37Rv GVSEGQVDNVR------------RYQIEPALHDGDYSGAAVAAANGLN--
MMAR_3652|M.marinum_M GITSSQVESLR------------RNKIEPKLRDGDWAGAAVAAADGLN--
MAV_2041|M.avium_104 GVNQSRVDALR------------HNKIEPALHDGDWSGAAVAAATGLD--
MAB_1706c|M.abscessus_ATCC_199 NVSDSEIENLR------------TNTIEPALRTSDWDGAAIKTATGLES-
MLBr_01629|M.leprae_Br4923 QILQSRPEDRRTFIEEAAGILKYRRRKEKALRKLDAMSANLARLTDLTTE
TH_1853|M.thermoresistible__bu AGSTAPVDLSG------------CDALSRALDAVAGEAVQTSGTEPLLID
MUL_1450|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2720|M.gilvum_PYR-GCK --------AGSGGGSVSWFGVIVALALIALALTILVLWQRRRRR------
Mvan_3816|M.vanbaalenii_PYR-1 --------AGSGGGSVSWTGVLVVLAVIALALAALVLWQRRRRR------
MSMEG_4484|M.smegmatis_MC2_155 P-------ASATGGGVSWPALLIVLGIIAVLIGILWIWSRRRRA------
Mb2374|M.bovis_AF2122/97 ----------RSPSSSSRVVLLVTVGIIVIVVAVLLVVMRHRNR------
Rv2345|M.tuberculosis_H37Rv ----------RSPSSSSRVVLLVTVGIIVIVVAVLLVVMRHRNR------
MMAR_3652|M.marinum_M ----------KSPRPSGGIPLLVVLSVLAVAVAIFWIVMRYRAS------
MAV_2041|M.avium_104 ----------TAPGSSGRVILLATLAALLVAVMGLLLVMRYRGR------
MAB_1706c|M.abscessus_ATCC_199 --------AASSSASIPWKPVLGALAFGAVLVGAFMLFSWFRTR------
MLBr_01629|M.leprae_Br4923 LRRQLKPLSRQAEVARRAATIQADLRDARLRLAADDLVSRQGQRDAIVEA
TH_1853|M.thermoresistible__bu RIDAEYRKYFTATGRPTGEWLAATKRLQAADEQVARCAARVAEVEDAVRR
MUL_1450|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2720|M.gilvum_PYR-GCK ---KRREAEFAAAQRVDPSDPEALAAVPLDALDDLSR----------KIV
Mvan_3816|M.vanbaalenii_PYR-1 ---KRREAEFAAAQRVDPSDANALAAVPLDALDELSR----------KIV
MSMEG_4484|M.smegmatis_MC2_155 ---KRRKAEFEAAKRVDPTDPDALASVPLEALDALSR----------EIV
Mb2374|M.bovis_AF2122/97 ---RRRADELAAARRVDPTNVMALAAVPLQALDDLSR----------SMV
Rv2345|M.tuberculosis_H37Rv ---RRRADELAAARRVDPTNVMALAAVPLQALDDLSR----------SMV
MMAR_3652|M.marinum_M ---RRRTNALAAARRVDPTDARALAAVPLDVLDELSR----------SMV
MAV_2041|M.avium_104 ---RRRAAALAAARRLDPTDLDALAALPLPTLDDLSR----------ALV
MAB_1706c|M.abscessus_ATCC_199 ---SRRRAEIEAAKGIDPSDAEALAKQPVTALDGLSK----------SIV
MLBr_01629|M.leprae_Br4923 ETMMRRDHDEAAARLAVASEELAAHEAALTELSGRAESVQQIWFGLSTLV
TH_1853|M.thermoresistible__bu HATLTESLAELEDGRRTADAQLAAAREAAEAVERLTR-----QLAEAQLA
MUL_1450|M.ulcerans_Agy99 ---------------------MSYVLTIPDALTSAAR-------------
: : :.
Mflv_2720|M.gilvum_PYR-GCK VDVDNEVRTS-ESELALAVEEFGAQDTAA-----FTRAVEGAKTTLAQAL
Mvan_3816|M.vanbaalenii_PYR-1 VDVDNELRTS-ESELALAVEEFGEQDTAP-----FSRAVANARTTLAQAL
MSMEG_4484|M.smegmatis_MC2_155 VDVDNAVRTS-QAELELAVEEFGAKRTEP-----FTTAVANARKALAQAF
Mb2374|M.bovis_AF2122/97 VDVDNAVRTS-TNELALAIEEFGERRTAP-----FTQAVNNAKAALSQAF
Rv2345|M.tuberculosis_H37Rv VDVDNAVRTS-TNELALAIEEFGERRTAP-----FTQAVNNAKAALSQAF
MMAR_3652|M.marinum_M VDVDNAVRTS-SNELAVAIDEFGEQRTAP-----FSQAVSNAKAALSQAF
MAV_2041|M.avium_104 VDVDNALRTS-ANELDLAVAEFGDQRTQP-----FTQAVTNAKAALSQAF
MAB_1706c|M.abscessus_ATCC_199 VNVDNAVRTS-EAELALAVEEFGTESTAP-----FQQAVDSAKKALAQAF
MLBr_01629|M.leprae_Br4923 ERVSATIRIAGERAYHLDVDPATPSDTDPDVLEAEAQQMEVAEQQLLAEL
TH_1853|M.thermoresistible__bu AEAAEATHTASVAALNERRRLRAEIEERTAAVAALQPEVDAALEAEATAR
MUL_1450|M.ulcerans_Agy99 -DVRGIGAAVDAANLTAAVPTAG-------------VLAAGADEVSAAVA
. *
Mflv_2720|M.gilvum_PYR-GCK NVRHILDDAVPETPMQRRDLLTRVIVAAAKADQELE-AQREAFAALRDLV
Mvan_3816|M.vanbaalenii_PYR-1 NVRQILDDAVPETPMQRRDLLTRVIVAAAKADRELE-AQREAFAQLRDLL
MSMEG_4484|M.smegmatis_MC2_155 NVRQILDDDVPETPLQQRDLLTRVIVSAARADRELE-AQSAAFEQLRDLV
Mb2374|M.bovis_AF2122/97 TVRQQLDDNTPETPAQRRELLTRVIVSAAHADRELA-SQTEAFEKLRDLV
Rv2345|M.tuberculosis_H37Rv TVRQQLDDNTPETPAQRRELLTRVIVSAAHADRELA-SQTEAFEKLRDLV
MMAR_3652|M.marinum_M SVRQQLDDSTPETPAQRRDLLTRVIVSAANADRELE-SQTEAFEKLRDLV
MAV_2041|M.avium_104 TVRQQLDDGMPETPAQRRELLTQVIVSAARADRELE-SQTEAFEGLRDLV
MAB_1706c|M.abscessus_ATCC_199 SVRKQLDDAIPETPLEQRRLLIDVITTAARADRTLE-DQSSAFDALRNLV
MLBr_01629|M.leprae_Br4923 AVARTQLEAARAELADRERHAVEADKAHLEAVRAEA-DRREGLALLAGQV
TH_1853|M.thermoresistible__bu EVQQEADTAAERAREAADAARERVDTARQAVQRLADRAERDTLADRLRRI
MUL_1450|M.ulcerans_Agy99 AVFCAHAQDYQALSAEATQFQTRFVSALSNAGSAYAAAEAAAASPLATVQ
* : . .
Mflv_2720|M.gilvum_PYR-GCK INAPSRLDTLTQQMIDLTTRITPAEQTLQQLKSQFAASA-----------
Mvan_3816|M.vanbaalenii_PYR-1 INAPSRLDTLTQQMVDLTARLTPAEQTLEQLKSQFAETA-----------
MSMEG_4484|M.smegmatis_MC2_155 INAPARLDLMTQQMVDLSARIETSQQTLAALHTQFDARA-----------
Mb2374|M.bovis_AF2122/97 INAPARLDLLTQQYVELTTRIGPTQQRLAELHTEFDAAA-----------
Rv2345|M.tuberculosis_H37Rv INAPARLDLLTQQYVELTTRIGPTQQRLAELHTEFDAAA-----------
MMAR_3652|M.marinum_M INAPARLDLLTQRYIELTTRIAPTEQRLVELHDEFGATA-----------
MAV_2041|M.avium_104 INAPSRLDGLTQQYVELTARIGPAEQQLAALHNEFSAAA-----------
MAB_1706c|M.abscessus_ATCC_199 INAPAKLDTLTQQVVAVTARLPESERILGQLRTEFDAAA-----------
MLBr_01629|M.leprae_Br4923 ETMRARIESIDDSVARLSERIEEVTARTQQILAEFETVQGRVGELDQSEV
TH_1853|M.thermoresistible__bu DAAATELARVDGELATLTVTEAALRQIEAAELAVERAAG-----------
MUL_1450|M.ulcerans_Agy99 EDLLAVINAPTQALLGRPLIGNGADGTAANPNGGAGGLL-----------
: : .
Mflv_2720|M.gilvum_PYR-GCK ---------------------------------LVSVSDNIDEARSRLAY
Mvan_3816|M.vanbaalenii_PYR-1 ---------------------------------LVSVSDNIDEARQRLAF
MSMEG_4484|M.smegmatis_MC2_155 ---------------------------------LESVAGNVDTARERLAF
Mb2374|M.bovis_AF2122/97 ---------------------------------MTSIAGNVTTATERLAF
Rv2345|M.tuberculosis_H37Rv ---------------------------------MTSIAGNVTTATERLAF
MMAR_3652|M.marinum_M ---------------------------------LSSISANVASAHELLAF
MAV_2041|M.avium_104 ---------------------------------LTSVSGNVTAAKERLAF
MAB_1706c|M.abscessus_ATCC_199 ---------------------------------LASIGDNVAEATERVRF
MLBr_01629|M.leprae_Br4923 HLDEQHERAVAALRFANERVAELQSAERDAERQVVSLRARIDALTMGLER
TH_1853|M.thermoresistible__bu ----------------------QAELASAHIELTAAVDLELRVGDEQLTI
MUL_1450|M.ulcerans_Agy99 ------------------------------------YGNGGNGYSSTTAE
Mflv_2720|M.gilvum_PYR-GCK ADQSITTARTLVSRPAH-RQGGLVDAIH----------------SAEAAL
Mvan_3816|M.vanbaalenii_PYR-1 ADQSITTARGLVSRPAD-RQGGLVDAIH----------------AAEAAL
MSMEG_4484|M.smegmatis_MC2_155 ADRNITTARGLVSRPAA-DQTGLVDAVR----------------AAESAL
Mb2374|M.bovis_AF2122/97 ADRNISAARDLADQAVSGRQAGLVDAVR----------------AAESAL
Rv2345|M.tuberculosis_H37Rv ADRNISAARDLADQAVSGRQAGLVDAVR----------------AAESAL
MMAR_3652|M.marinum_M ADSNISSARELSAKAVSGQQTGLVDAVR----------------AAESAL
MAV_2041|M.avium_104 ADRNIGTARELAGQAVSGQQGRLVDAVR----------------AAESAL
MAB_1706c|M.abscessus_ATCC_199 ADSRITHGRELAARALEGQQMSLVDAIR----------------GAESAL
MLBr_01629|M.leprae_Br4923 KDGAAWLARNYSDTGLLGSIAKLVKVRPGYEAALAAVLGPAADALAVDSL
TH_1853|M.thermoresistible__bu PAGGSWTAGATAPTEIELPGLLTARIVPG-----------APAAQMQETL
MUL_1450|M.ulcerans_Agy99 VAGGNGGAAGLIGNGGAGGGGGAR---------------------AAGGY
.
Mflv_2720|M.gilvum_PYR-GCK GQARTLLDAVDSAST-----------------------------------
Mvan_3816|M.vanbaalenii_PYR-1 GQARTLLDAVDSAST-----------------------------------
MSMEG_4484|M.smegmatis_MC2_155 SQARTLLDAVDSAST-----------------------------------
Mb2374|M.bovis_AF2122/97 GQARALLDAVDSAAT-----------------------------------
Rv2345|M.tuberculosis_H37Rv GQARALLDAVDSAAT-----------------------------------
MMAR_3652|M.marinum_M GQARSLLDAVDSAAG-----------------------------------
MAV_2041|M.avium_104 GQARSLLDAVDHAAG-----------------------------------
MAB_1706c|M.abscessus_ATCC_199 TQANALLDAIDNAAN-----------------------------------
MLBr_01629|M.leprae_Br4923 GAARSALTALKEADAGRATLVLADWLADAGPACVTGLPDGAQRALDLIEA
TH_1853|M.thermoresistible__bu DVARAALADALQHAG-----------------------------------
MUL_1450|M.ulcerans_Agy99 GGHGGWLYGSGGAGG-----------------------------------
*
Mflv_2720|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3816|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4484|M.smegmatis_MC2_155 --------------------------------------------------
Mb2374|M.bovis_AF2122/97 --------------------------------------------------
Rv2345|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3652|M.marinum_M --------------------------------------------------
MAV_2041|M.avium_104 --------------------------------------------------
MAB_1706c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01629|M.leprae_Br4923 PPWLQGALIAMLYGVVVVNYLAEALGVVDICPQLRVVTVDGDLVGAGWVS
TH_1853|M.thermoresistible__bu --------------------------------------------------
MUL_1450|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2720|M.gilvum_PYR-GCK ----------DINRAVTGLPAVIADIQNGINSAGAQLAQG---SVAVATE
Mvan_3816|M.vanbaalenii_PYR-1 ----------DINRAVTGLPAVIADIQNGINQAGAQLAQG---NVAVATE
MSMEG_4484|M.smegmatis_MC2_155 ----------DINRALAGLPAAVADIEAGIEQANDLLAQP---DTPQADK
Mb2374|M.bovis_AF2122/97 ----------DIRHAVASLPAVVADIQTGIKRANQHLQQAQQPQTGRTGD
Rv2345|M.tuberculosis_H37Rv ----------DIRHAVASLPAVVADIQTGIKRANQHLQQAQQPQTGRTGD
MMAR_3652|M.marinum_M ----------DIRHAVATMPSVLADIQAGIQHANEQLQKSPANKSAYAAE
MAV_2041|M.avium_104 ----------DIRHAIDQLPSAMADIENDIKRAAELLAATRDTKSGHAAE
MAB_1706c|M.abscessus_ATCC_199 ----------NIRHAIDSLAASIADTKSDIAQAEEFQKQG---RLPSSEE
MLBr_01629|M.leprae_Br4923 GGSGRRLSTLEVTSEIDKAGAELAAAEAHMAQLNAALSGALSEQVAHSDA
TH_1853|M.thermoresistible__bu --------VADVASARSQVERRRELSTARETFAATVVALTGEDTLERLRA
MUL_1450|M.ulcerans_Agy99 -----------DGGSGAAISAGVVAGAGGAGGAGGSSSGGNANGGAGGAG
Mflv_2720|M.gilvum_PYR-GCK LSDARDAAVQ----------------------------------------
Mvan_3816|M.vanbaalenii_PYR-1 LSTARDAAVQ----------------------------------------
MSMEG_4484|M.smegmatis_MC2_155 LATARDAAVQ----------------------------------------
Mb2374|M.bovis_AF2122/97 LIAARDAAAR----------------------------------------
Rv2345|M.tuberculosis_H37Rv LIAARDAAAR----------------------------------------
MMAR_3652|M.marinum_M LIAARDAAAR----------------------------------------
MAV_2041|M.avium_104 LAAARDAATR----------------------------------------
MAB_1706c|M.abscessus_ATCC_199 LTKAHDAAVA----------------------------------------
MLBr_01629|M.leprae_Br4923 TEQALVALNESDTAILSMYDQLGRLGQEVRAAEAEWESLLAQREELEARR
TH_1853|M.thermoresistible__bu RLAELDAAASDDTG------------------------------------
MUL_1450|M.ulcerans_Agy99 GAGALGGLLNG---------------------------------------
.
Mflv_2720|M.gilvum_PYR-GCK ------AVAEAQSSGETDPLGAFTRLTQADADLDRLLAEVAEER------
Mvan_3816|M.vanbaalenii_PYR-1 ------AVSQAQSTGNSDPLGAFTRLTQADADLDRLLAEVAEER------
MSMEG_4484|M.smegmatis_MC2_155 ------AAGEAKSNGTADPLGTFTRLTQADADLDQLLATVHEQR------
Mb2374|M.bovis_AF2122/97 ------ALDRAR--GAADPLTAFDQLTKVDADLDRLLATLAEEQ------
Rv2345|M.tuberculosis_H37Rv ------ALDRAR--GAADPLTAFDQLTKVDADLDRLLATLAEEQ------
MMAR_3652|M.marinum_M ------AVDNARVTGAADPLSAFAQLTTADADLDRLLAAIAQEQ------
MAV_2041|M.avium_104 ------AVEGARAGAPDDPLGAFGQLTKADAGLNAVLAAVAQER------
MAB_1706c|M.abscessus_ATCC_199 ------AVADAERIGATDPLTAFTHLAAADAQLDKLLAAAQEER------
MLBr_01629|M.leprae_Br4923 VSILEEVVELETRLHNVEQIQHVHALDENSAAARQLIVAAAEEARGVEVE
TH_1853|M.thermoresistible__bu ------ELGVDDAQAELTAAERAYQQAHTDCETHRKAAVLAARR------
MUL_1450|M.ulcerans_Agy99 ------AGGNGGAGGAGGNGGDISPLAGGNAGNGGVGGSGGDAG------
..
Mflv_2720|M.gilvum_PYR-GCK -------------------------ETAARLSRTFDQALFNAQSRVRAVS
Mvan_3816|M.vanbaalenii_PYR-1 -------------------------ETAERLSRTFDQALFNAQSRVRAVS
MSMEG_4484|M.smegmatis_MC2_155 -------------------------EAAERLARTLEQAIFTAESRITAVS
Mb2374|M.bovis_AF2122/97 -------------------------ATADRLNRSLEQALFTAESRVRAVS
Rv2345|M.tuberculosis_H37Rv -------------------------ATADRLNRSLEQALFTAESRVRAVS
MMAR_3652|M.marinum_M -------------------------ANAEHLRRSLEQALFTAESRIRAVS
MAV_2041|M.avium_104 -------------------------AAAERLARSLEQALFTAQSRVRAVS
MAB_1706c|M.abscessus_ATCC_199 -------------------------AAAERRARVLDQALVAARQRLDAVN
MLBr_01629|M.leprae_Br4923 ALLAVRTAEERVNAVCGRANSLRRAAAAEREVRLRDQQAHAARIRAAAVA
TH_1853|M.thermoresistible__bu ------------------------LAEKSQTAAALREKLTAARTELDTAA
MUL_1450|M.ulcerans_Agy99 -----------------------------------LFGLGGAGGSGGGGG
*
Mflv_2720|M.gilvum_PYR-GCK DYIDTRRGAIGPEARTR--------LAEAVRQLQAARDKQDTNLNEAIAH
Mvan_3816|M.vanbaalenii_PYR-1 DYIDTRRGAIGPEARTR--------LAEAVRQLQAARDKRETNLNEAIAH
MSMEG_4484|M.smegmatis_MC2_155 DYIETRRGSIGPEARTR--------LAEATRQLEAARAKRSTNPNEAVAH
Mb2374|M.bovis_AF2122/97 EYIDTRRGSIGPEARTR--------LAEAKRQLEAAHDRKSSNPTEAIAY
Rv2345|M.tuberculosis_H37Rv EYIDTRRGSIGPEARTR--------LAEAKRQLEAAHDRKSSNPTEAIAY
MMAR_3652|M.marinum_M DYIDTRRGSIGPEARTR--------LAEAGRRLDAAQSYRSTNPTEAIAQ
MAV_2041|M.avium_104 DYIDTRRGSIGPEARTR--------LAEAQRHLHAAADRRATDPADAIAH
MAB_1706c|M.abscessus_ATCC_199 QYIGLHRGAVGARTRWN--------LDEAQRRLAAAEQSRASNPSDAILF
MLBr_01629|M.leprae_Br4923 AAVTDCGQLLASRLTQA--------VDLAARHRDALATERQQRSVAIAAV
TH_1853|M.thermoresistible__bu ARLAAQRADVDDETLVVRAAAHGEEAERAAVRVAQLNAELSAAQPDQVAA
MUL_1450|M.ulcerans_Agy99 DSVGLQSGAGGGGAGGD------------GGLLNGTGGAGGAGGDGGSAL
:
Mflv_2720|M.gilvum_PYR-GCK ANGAAMLAAQAQSLANSDVTAAQRHFNGPYGGGGGGGQMGAVIG------
Mvan_3816|M.vanbaalenii_PYR-1 ANGAAMLAAQAQSLANSDVTAAQRHFSGPYGGGGGG-QMGAVIG------
MSMEG_4484|M.smegmatis_MC2_155 ANGASTLAAQAQSLANDDVRAAQRSYTSHHGGGGAD--MGAVLG------
Mb2374|M.bovis_AF2122/97 ANAASTLAAHAQSLANADVQSAQRAYT---RRGGNN--AGAILG------
Rv2345|M.tuberculosis_H37Rv ANAASTLAAHAQSLANADVQSAQRAYT---RRGGNN--AGAILG------
MMAR_3652|M.marinum_M ANAASTLAANAQSLANSDVQAAQRAYT---RQGGNN--TGAVLG------
MAV_2041|M.avium_104 ANAASTLAAEAQSLANGDVQAARRAYP---RGGGGD--MGAMLG------
MAB_1706c|M.abscessus_ATCC_199 ANGAAELATQAQYSAQQEVQSAQRYYG---NGYGGYSVAGDVAGNV----
MLBr_01629|M.leprae_Br4923 RYEVNTLRVRLATLTDSLHRDEVANVQAALRIEQLEQLVLEQFGIAPVDL
TH_1853|M.thermoresistible__bu ALDTAARHAETVHAEHRRTADALRELNAQLEVYGSEGRKGELDAAKAE--
MUL_1450|M.ulcerans_Agy99 SGGTGGNGGAGGAGGDAELTGDG-------GSGGAGGDGGSPGG------
. . .
Mflv_2720|M.gilvum_PYR-GCK -------------GILIGNVLSGVLRGGLGGGGFGGGFG--GGGFGGG--
Mvan_3816|M.vanbaalenii_PYR-1 -------------GILIGNVLSGALRGGFGGGGFGGGFG--GGGFGGG--
MSMEG_4484|M.smegmatis_MC2_155 -------------GIIIGNVLRGGFGGGGGYGGYGGGFGGFGGGFGGGRS
Mb2374|M.bovis_AF2122/97 -------------GIIIGDLLSGGTRGGLG-GWIPTSFGGSSNAPGSS--
Rv2345|M.tuberculosis_H37Rv -------------GIIIGDLLSGGTRGGLG-GWIPTSFGGSSNAPGSS--
MMAR_3652|M.marinum_M -------------GIIIGDLLSGGMRGGFG-GWSPTSFGGSSGSSGDS--
MAV_2041|M.avium_104 -------------GIIIGDLLSSGMRGGFG-GWSPASFGGSTSSSG----
MAB_1706c|M.abscessus_ATCC_199 ------------AGAVIGGILRGMLSGGAGHHSSWSGSGSSSYGGSSR--
MLBr_01629|M.leprae_Br4923 IAEYGPQVALLPTELEMAEFQQARERGEQVTSPAPMPYDRATQERRAKRA
TH_1853|M.thermoresistible__bu ------------REQAEAEFLRIGRLARAVKLLRETMLRHRDASRRRYVD
MUL_1450|M.ulcerans_Agy99 ---------------------TGAAGGAGGDGGQRGGSPGAPGAAGV---
.
Mflv_2720|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3816|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4484|M.smegmatis_MC2_155 SGRPTSY-------------------------------------------
Mb2374|M.bovis_AF2122/97 --------------------------------------------------
Rv2345|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3652|M.marinum_M --------------------------------------------------
MAV_2041|M.avium_104 --------------------------------------------------
MAB_1706c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01629|M.leprae_Br4923 ERELAELGRVNPLALEEFAALEERYNFLSTQLEDVKGARKDLLDVVAEVD
TH_1853|M.thermoresistible__bu P-------------------------------------------------
MUL_1450|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2720|M.gilvum_PYR-GCK ---------------------GGGGFSGGGGRF-----------------
Mvan_3816|M.vanbaalenii_PYR-1 ---------------------GGG-FSGGGGRF-----------------
MSMEG_4484|M.smegmatis_MC2_155 ---------------GGSSHSSGRNYGGGGGRF-----------------
Mb2374|M.bovis_AF2122/97 ---------------------PDGGFLGGGGRF-----------------
Rv2345|M.tuberculosis_H37Rv ---------------------PDGGFLGGGGRF-----------------
MMAR_3652|M.marinum_M ---------------------SGGGFLGGGGRF-----------------
MAV_2041|M.avium_104 -----------------------GGVLGGGGRF-----------------
MAB_1706c|M.abscessus_ATCC_199 --------------------SSGSSFRGGGGRF-----------------
MLBr_01629|M.leprae_Br4923 ARILQVFSDAFVDVEREFRGVFTSLFPGGEGRLRLTDPDDMLTTGIEVEA
TH_1853|M.thermoresistible__bu ---------------------FRAEVERLGRIVFGDSFEVEIDSDLCIRS
MUL_1450|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2720|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3816|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4484|M.smegmatis_MC2_155 --------------------------------------------------
Mb2374|M.bovis_AF2122/97 --------------------------------------------------
Rv2345|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3652|M.marinum_M --------------------------------------------------
MAV_2041|M.avium_104 --------------------------------------------------
MAB_1706c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01629|M.leprae_Br4923 RPSGKKVSRLSLLSGGEKSLIAVAMLVA---IFKARPSPFYIMDEVEAAL
TH_1853|M.thermoresistible__bu RTLAGRTVDYESLSGGAKEQLGIVARLAGAALVARDDTVPVVIDDALGFT
MUL_1450|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2720|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3816|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4484|M.smegmatis_MC2_155 --------------------------------------------------
Mb2374|M.bovis_AF2122/97 --------------------------------------------------
Rv2345|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3652|M.marinum_M --------------------------------------------------
MAV_2041|M.avium_104 --------------------------------------------------
MAB_1706c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01629|M.leprae_Br4923 DDVNLCRLIGVFEQLRGQSQLIIITHQKPTMEVADTLYGVTMQGDGITAV
TH_1853|M.thermoresistible__bu DAERLVKMGAVFDAVGGDGQVIVLTCSPDRYAGISDAHRIELTA------
MUL_1450|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2720|M.gilvum_PYR-GCK ------------------
Mvan_3816|M.vanbaalenii_PYR-1 ------------------
MSMEG_4484|M.smegmatis_MC2_155 ------------------
Mb2374|M.bovis_AF2122/97 ------------------
Rv2345|M.tuberculosis_H37Rv ------------------
MMAR_3652|M.marinum_M ------------------
MAV_2041|M.avium_104 ------------------
MAB_1706c|M.abscessus_ATCC_199 ------------------
MLBr_01629|M.leprae_Br4923 ISQRMRGQQVESLVTSSS
TH_1853|M.thermoresistible__bu ------------------
MUL_1450|M.ulcerans_Agy99 ------------------