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MSYVLTIPDALTSAARDVRGIGAAVDAANLTAAVPTAGVLAAGADEVSAAVAAVFCAHAQDYQALSAEAT QFQTRFVSALSNAGSAYAAAEAAAASPLATVQEDLLAVINAPTQALLGRPLIGNGADGTAANPNGGAGGL LYGNGGNGYSSTTAEVAGGNGGAAGLIGNGGAGGGGGARAAGGYGGHGGWLYGSGGAGGDGGSGAAISAG VVAGAGGAGGAGGSSSGGNANGGAGGAGGAGALGGLLNGAGGNGGAGGAGGNGGDISPLAGGNAGNGGVG GSGGDAGLFGLGGAGGSGGGGGDSVGLQSGAGGGGAGGDGGLLNGTGGAGGAGGDGGSALSGGTGGNGGA GGAGGDAELTGDGGSGGAGGDGGSPGGTGAAGGAGGDGGQRGGSPGAPGAAGV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1450 | - | - | 100% (403) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_4399 | - | e-125 | 56.06% (437) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_3507 | - | e-123 | 57.60% (434) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1121 | PE_PGRS22 | 1e-126 | 57.14% (448) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 3e-68 | 51.53% (295) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | 1e-126 | 57.14% (448) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 7e-10 | 36.05% (86) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 1e-32 | 36.69% (308) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_4127 | - | 1e-129 | 57.14% (441) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 2e-24 | 42.61% (176) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-66 | 49.06% (318) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 3e-37 | 37.46% (299) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 4e-69 | 52.84% (282) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mb1121|M.bovis_AF2122/97 --------------------------------------------------
Rv1091|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1450|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4127|M.marinum_M --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mb1121|M.bovis_AF2122/97 ----------MSFVIAAPEALVAVASDLAGIGSALAEANAAALAPTTALL
Rv1091|M.tuberculosis_H37Rv ----------MSFVIAAPEALVAVASDLAGIGSALAEANAAALAPTTALL
MUL_1450|M.ulcerans_Agy99 ----------MSYVLTIPDALTSAARDVRGIGAAVDAANLTAAVPTAGVL
MMAR_4127|M.marinum_M ----------MSYFIAVPDELALAATELDSIGAALSVANVAAALPTTGIL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAV
MAV_4827|M.avium_104 ------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAAT
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mb1121|M.bovis_AF2122/97 AAGADEVSAAIAALFGAHGQAYQTVSAQASAFHAQFVQALTGGGGAYAAA
Rv1091|M.tuberculosis_H37Rv AAGADEVSAAIAALFGAHGQAYQTVSAQASAFHAQFVQALTGGGGAYAAA
MUL_1450|M.ulcerans_Agy99 AAGADEVSAAVAAVFCAHAQDYQALSAEATQFQTRFVSALSNAGSAYAAA
MMAR_4127|M.marinum_M AAGADDVSTAIAALFAGHAQAYQALSTAASTFHTQFVRALNLSGGAYAAA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDG
MAV_4827|M.avium_104 ASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAARRI
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mb1121|M.bovis_AF2122/97 EAANVS--------------------------------AAQSTDQRLLDL
Rv1091|M.tuberculosis_H37Rv EAANVS--------------------------------AAQSTDQRLLDL
MUL_1450|M.ulcerans_Agy99 EAAAAS--------------------------------PLATVQEDLLAV
MMAR_4127|M.marinum_M DAANAS--------------------------------PLQTLEQDLLGV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 P---------------------------------------SILSPSLLSP
MAV_4827|M.avium_104 DNVMLVS----------------------------AFLAAAALAQNVGGA
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mb1121|M.bovis_AF2122/97 IN--------------------GPTQALLG--------RPLIGDGANGGP
Rv1091|M.tuberculosis_H37Rv IN--------------------GPTQALLG--------RPLIGDGANGGP
MUL_1450|M.ulcerans_Agy99 IN--------------------APTQALLG--------RPLIGNGADGTA
MMAR_4127|M.marinum_M LN--------------------APTQALLG--------RPLIGDGADGTA
MLBr_01183|M.leprae_Br4923 ------------------------MPLFLN----------AEPQALTAAA
MAB_4284c|M.abscessus_ATCC_199 RD-----------------------NDFLSHN-----DTDFASHNPIASG
MAV_4827|M.avium_104 MG-------------------YERTAVLLVEP------DTATLAVVETSD
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGG--NGGNGGNGL
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGG--NGGNGGNGL
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG---NGGNGGVGW
TH_3810|M.thermoresistible__bu -----------------------VDGDGGSGGRTGLFSKLSRGGDGGDGG
Mb1121|M.bovis_AF2122/97 GQ-DGGPGGLLYGNGGNGGTSTTAGVAGGNGGAAGLIG---NGGAGGGGG
Rv1091|M.tuberculosis_H37Rv GQ-DGGPGGLLYGNGGNGGTSTTAGVAGGNGGAAGLIG---NGGAGGGGG
MUL_1450|M.ulcerans_Agy99 ANPNGGAGGLLYGNGGNGYSSTTAEVAGGNGGAAGLIG---NGGAGGGGG
MMAR_4127|M.marinum_M PGQGGGAGGLLYGNGGSGAAGTNTGVAGGAGGDAGLIG---NGGSGGAGG
MLBr_01183|M.leprae_Br4923 NTLEGLSAATVASN--AAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQ
MAB_4284c|M.abscessus_ATCC_199 NQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGP
MAV_4827|M.avium_104 GSIPDVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVGSGVDVA
.: * .
Mflv_5091|M.gilvum_PYR-GCK GGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGA
Mvan_1264|M.vanbaalenii_PYR-1 GSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGA
MSMEG_0868|M.smegmatis_MC2_155 AGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGG
TH_3810|M.thermoresistible__bu LGGNGGHGGGTGIISLLSLAGNGGNGGNGYR----------------TTD
Mb1121|M.bovis_AF2122/97 AGAAGGNGGAGG--WLYGNGGAGGAGGTSVIPGVAGGNGGAGGSAGLWGT
Rv1091|M.tuberculosis_H37Rv AGAAGGNGGAGG--WLYGNGGAGGAGGTSVIPGVAGGNGGAGGSAGLWGT
MUL_1450|M.ulcerans_Agy99 ARAAGGYGGHGG--WLYGSGGAGGDGGS----------------------
MMAR_4127|M.marinum_M GGAAGGAGGNGG--WLFGAGGNGGFGGA----------------------
MLBr_01183|M.leprae_Br4923 AHASQGATNHQD--LIQSLLTSSSAYAG----------------------
MAB_4284c|M.abscessus_ATCC_199 IASGQGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVG---------GDY
MAV_4827|M.avium_104 PLKQVLQTTTFLDVSVAEEPETALARGAALAAANAPLFASSTAALAYAQD
Mflv_5091|M.gilvum_PYR-GCK TGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-------------
Mvan_1264|M.vanbaalenii_PYR-1 TGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-------------
MSMEG_0868|M.smegmatis_MC2_155 TGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPN
TH_3810|M.thermoresistible__bu NNALDGGHGGNGGNVGFFSLFNLGGAGGWGGSGVDG--------------
Mb1121|M.bovis_AF2122/97 GGAGGDGGNGRSGPVNVAGSAGGNGGAGGAAGLFGDAGAGGNGGKGGAGG
Rv1091|M.tuberculosis_H37Rv GGAGGDGGNGRSGPVNVAGSAGGNGGAGGAAGLFGDAGAGGNGGKGGAGG
MUL_1450|M.ulcerans_Agy99 -------------------------------------------------G
MMAR_4127|M.marinum_M --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TNVSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDR-------------
MAV_4827|M.avium_104 PGTGAVDQYSLPDYLYVPVDPEPGDDELAYSAVGEED-------------
Mflv_5091|M.gilvum_PYR-GCK -AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 -AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG--------------
MSMEG_0868|M.smegmatis_MC2_155 VTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVD
TH_3810|M.thermoresistible__bu --VDVVGGNPDGGTPGAHG--ESHTPGVYTDR------------------
Mb1121|M.bovis_AF2122/97 AAFSINFTAGDGGAGGAGGSGGHALLWGAGGAGGNGG-------------
Rv1091|M.tuberculosis_H37Rv AAFSINFTAGDGGAGGAGGSGGHALLWGAGGAGGNGG-------------
MUL_1450|M.ulcerans_Agy99 AAISAGVVAGAGGAGGAGGS------------------------------
MMAR_4127|M.marinum_M -----ATGLGPGGAGGAGGHGG----------------------------
MLBr_01183|M.leprae_Br4923 --------TETANHDSL---------------------------------
MAB_4284c|M.abscessus_ATCC_199 -STNIGSGNTTNTEIGSHNQANIGTSTSAGGSAAVGG-------------
MAV_4827|M.avium_104 -AESPTVVIEKLFLPEDSEPRRRPVLLVGSGLAVVGIS------------
Mflv_5091|M.gilvum_PYR-GCK --AVGAAGAAG------TVGTAGATGGTG---------------TGANGG
Mvan_1264|M.vanbaalenii_PYR-1 --AIGTAGVAG------AAGTAGATGGTG---------------VGGNGG
MSMEG_0868|M.smegmatis_MC2_155 GHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGG
TH_3810|M.thermoresistible__bu --------------------------------------------QGEDGE
Mb1121|M.bovis_AF2122/97 ----SGGTGGAGGSTAGAGGNGGAGGGGGTGGLLFGNGGAGGHGAAAGNG
Rv1091|M.tuberculosis_H37Rv ----SGGTGGAGGSTAGAGGNGGAGGGGGTGGLLFGNGGAGGHGAAAGNG
MUL_1450|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4127|M.marinum_M --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------------------------------NAG
MAV_4827|M.avium_104 --------------------------------------------AVLALE
Mflv_5091|M.gilvum_PYR-GCK AGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGG
Mvan_1264|M.vanbaalenii_PYR-1 AGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGG
MSMEG_0868|M.smegmatis_MC2_155 HSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGE
TH_3810|M.thermoresistible__bu DGTGTGIGGRGGNG------------------------------------
Mb1121|M.bovis_AF2122/97 LAAGNGVSSSGGGG---------------AGGTGGAGGDGGAGGAGGNAR
Rv1091|M.tuberculosis_H37Rv LAAGNGVSSSGGGG---------------AGGTGGAGGDGGAGGAGGNAR
MUL_1450|M.ulcerans_Agy99 --------SSGG--------------------------------------
MMAR_4127|M.marinum_M -----WLYGSGGTG---------------GDG------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAG-----------------------------------
MAV_4827|M.avium_104 IALAIGIRTTGTVALQP---------------------------------
Mflv_5091|M.gilvum_PYR-GCK Q--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG---------
Mvan_1264|M.vanbaalenii_PYR-1 Q--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG---------
MSMEG_0868|M.smegmatis_MC2_155 IYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASG
TH_3810|M.thermoresistible__bu ------------------GSSSGTHPMAEDG-------------------
Mb1121|M.bovis_AF2122/97 L--------WGVGGAGGAGGDGGAGGAGGKG-------------------
Rv1091|M.tuberculosis_H37Rv L--------WGVGGAGGAGGDGGAGGAGGKG-------------------
MUL_1450|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4127|M.marinum_M --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------NAGLAGNAGLAGNAG-------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----LQGGKGGDGGAGGKGGDADSMGS------------------AGATG
Mvan_1264|M.vanbaalenii_PYR-1 ----LQGGQGGDGGTGGTGGDATSMGE------------------AGATG
MSMEG_0868|M.smegmatis_MC2_155 TAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANG
TH_3810|M.thermoresistible__bu -----EHVKALDGRPGLDGG----------------------------NG
Mb1121|M.bovis_AF2122/97 ------GSGLSGNANGGAGGD-------------------------SGRG
Rv1091|M.tuberculosis_H37Rv ------GSGLSGNANGGAGGD-------------------------SGRG
MUL_1450|M.ulcerans_Agy99 ------------NANGGAGG------------------------------
MMAR_4127|M.marinum_M -----------GFAKGGNGG------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----LAGNAGLAGNAGLAGNAG-----------------------LAGNA
MAV_4827|M.avium_104 -----TPNQHLIVPTEQAPAPPPVQAS-------------------APQP
Mflv_5091|M.gilvum_PYR-GCK GKGGNGGNGGRGGLFG---------------KGGNAGNGAD---------
Mvan_1264|M.vanbaalenii_PYR-1 GKGGNGGNGGRGSLFG---------------RGGNAGNGGN---------
MSMEG_0868|M.smegmatis_MC2_155 AVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPN
TH_3810|M.thermoresistible__bu SHGGNGGHGGRGGFLG----------------------------------
Mb1121|M.bovis_AF2122/97 GTGGAGGEGGAAGLLVGTGGHGGDGGAGGAAVKGGDGGAAA---------
Rv1091|M.tuberculosis_H37Rv GTGGAGGEGGAAGLLVGTGGHGGDGGAGGAAVKGGDGGAAA---------
MUL_1450|M.ulcerans_Agy99 ----AGGAGALGGLLN----------------------------------
MMAR_4127|M.marinum_M ----AGGAGGDAGLLG----------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAG----------------------------------
MAV_4827|M.avium_104 KISVPEPVAAPKPLSPP---------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------------GGTGGAGGAGGTGG-TGGAGGTGG-------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------GGTGGNGGNGGTGG-TGGNGGTGG-------------
MSMEG_0868|M.smegmatis_MC2_155 GPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHST
TH_3810|M.thermoresistible__bu ------------IGGSGGWGGHGGNGGDTDADGGNGG-------------
Mb1121|M.bovis_AF2122/97 ------------GTGIAGAGGRGGAGG-SGGSGGDGG-------------
Rv1091|M.tuberculosis_H37Rv ------------GTGIAGAGGRGGAGG-SGGSGGDGG-------------
MUL_1450|M.ulcerans_Agy99 -----------------GAGGNGGAGG-AGGNGGD---------------
MMAR_4127|M.marinum_M ------------------AGGSGGTGG-AGATSGP---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------NAGLAGNAGLAGNAGLAGNAGLAGN-------------
MAV_4827|M.avium_104 ------------VAAPLPAAPPPAAPPLPEAPPIPAAP------------
Mflv_5091|M.gilvum_PYR-GCK ----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 ----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGG
TH_3810|M.thermoresistible__bu -----------------------------------------DGGNGGSAG
Mb1121|M.bovis_AF2122/97 -------------GGAAGPAGWLFGDGGAGGNGGAAAAGGAGGQAGGGGG
Rv1091|M.tuberculosis_H37Rv -------------GGAAGPAGWLFGDGGAGGNGGAAAAGGAGGQAGGGGG
MUL_1450|M.ulcerans_Agy99 ----------------------------------------ISPLAGGNAG
MMAR_4127|M.marinum_M ---------------------------------------ASSHFAGGAGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------AGLAGNAGLAGN
MAV_4827|M.avium_104 ----------------------PVVPVPVVVPPVPVPVPVRIPVPDPVSP
Mflv_5091|M.gilvum_PYR-GCK KGGTG----GTGGAGGTG----GDGGTGGTGGTGGTG---------GTGG
Mvan_1264|M.vanbaalenii_PYR-1 KGGTG----GTGGDGGTG----GTGGTGGTGGTGGTG---------GTGG
MSMEG_0868|M.smegmatis_MC2_155 RGGDG----ALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGG
TH_3810|M.thermoresistible__bu RGGTG----GLRGVFGIN--------------------------------
Mb1121|M.bovis_AF2122/97 NGGNG----GNGGNGGNGGNGATGGWLYGNGGAGGQG------------A
Rv1091|M.tuberculosis_H37Rv NGGNG----GNGGNGGNGGNGATGGWLYGNGGAGGQG------------A
MUL_1450|M.ulcerans_Agy99 NGGVG----GSGGDAG----------LFG---------------------
MMAR_4127|M.marinum_M AGGHGGLLYGDGGTGGFG--------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGLAG--NAGLAGNAGLAGNAAVAGNAAVAGNAAVAG----------NAA
MAV_4827|M.avium_104 PQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQS-------------
Mflv_5091|M.gilvum_PYR-GCK TGGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG----
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG----
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALI
TH_3810|M.thermoresistible__bu -GGNGRAG-----------------------------LGGRGXXXX----
Mb1121|M.bovis_AF2122/97 TAGAGGAG------------ANGVSSTNGG---GNGGIGGTGGSGG----
Rv1091|M.tuberculosis_H37Rv TAGAGGAG------------ANGVSSTNGGGTGGNGGIGGTGGSGG----
MUL_1450|M.ulcerans_Agy99 -------------------------------------LGGAGGSGG----
MMAR_4127|M.marinum_M ---------------------------------GDGGVGGAGGAGG----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGVLNTG-------------------------VSGAIGGSSHVGG----
MAV_4827|M.avium_104 -------------------------------PPQHQTPPGEGTPPK----
Mflv_5091|M.gilvum_PYR-GCK -------------TGGTGGQGG-LGGGGGTG-------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------TGGTGGQGG-LGGVGGTG-------------------
MSMEG_0868|M.smegmatis_MC2_155 RATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASG
TH_3810|M.thermoresistible__bu -------------GGGVG--------------------------------
Mb1121|M.bovis_AF2122/97 -------------AGGNAGLLG----------------------------
Rv1091|M.tuberculosis_H37Rv -------------AGGNAGLLG----------------------------
MUL_1450|M.ulcerans_Agy99 -------------GGGDS--------------------------------
MMAR_4127|M.marinum_M -------------GGGAAGLVG----------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------AINESLGGSGSVGG----------------------------
MAV_4827|M.avium_104 -------------PDGPGNYGG----------------------------
Mflv_5091|M.gilvum_PYR-GCK ----GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGL
Mvan_1264|M.vanbaalenii_PYR-1 ----GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGL
MSMEG_0868|M.smegmatis_MC2_155 TATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGL
TH_3810|M.thermoresistible__bu -------------------------------------AAVRSGNGVFSGG
Mb1121|M.bovis_AF2122/97 -----VGGAGG--------------------------HGASGGAGDRGGA
Rv1091|M.tuberculosis_H37Rv -----VGGAGG--------------------------HGASGGAGDRGGA
MUL_1450|M.ulcerans_Agy99 -------------------------------------------VGLQSGA
MMAR_4127|M.marinum_M -----AGGAGG--------------------------NGGAG-LGILGEA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------STAVGGGAHTGV
MAV_4827|M.avium_104 ------------------------------------GHVPTPGAGGSGGS
Mflv_5091|M.gilvum_PYR-GCK GGFG---------------GSGGTGGQGGLGGPGGSTGGAGGAGG--QAG
Mvan_1264|M.vanbaalenii_PYR-1 GGFG---------------GVGGTGGQGGQGGPGGSTGGAGGAGG--QAG
MSMEG_0868|M.smegmatis_MC2_155 GGNG---------------GDGVVNTTANAANPGSATGTATGGDGGKATG
TH_3810|M.thermoresistible__bu GGTP---------------SAGFGVPTTIQFPAGSCTSRAVSREGIMPSS
Mb1121|M.bovis_AF2122/97 GGTGFISSDGGAGGDGGDGGNGGAGGTGGLLFGAGGNGGPGGSGGAADIG
Rv1091|M.tuberculosis_H37Rv GGTGFISSDGGAGGDGGDGGNGGAGGTGGLLFGAGGNGGPGGSGGAADIG
MUL_1450|M.ulcerans_Agy99 GG-------------------GGAGGDGGLLNGTGGAGGAGGDGGSALSG
MMAR_4127|M.marinum_M GG------------------NGGGGGAGGLLVGAGGAGGAGGDGGLHLSS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGGVSTGVG---------VGSHVGGGISESLGGSGSVGGSTAVGGGAHTG
MAV_4827|M.avium_104 GGGHVPTP-----------GAGGSGGSGGGHVPTPGTGGPGGTGGSGGGH
Mflv_5091|M.gilvum_PYR-GCK TAGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG----
Mvan_1264|M.vanbaalenii_PYR-1 VAGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG----
MSMEG_0868|M.smegmatis_MC2_155 TASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNAL
TH_3810|M.thermoresistible__bu RAAS--------------ARAGAACASSTSRSRRSFCCSRA---------
Mb1121|M.bovis_AF2122/97 GNGGAGNGG---------GTDGNGGNGGSGG-GAGSGGDGGGAGGNGAWL
Rv1091|M.tuberculosis_H37Rv GNGGAGNGG---------GTDGNGGNGGSGG-GAGSGGDGGGAGGNGAWL
MUL_1450|M.ulcerans_Agy99 GTG------------------GNGGAGGAGG-DAELTGDGG---------
MMAR_4127|M.marinum_M FVG----------------PGGSGGDGGAGGTGGWLYGDGG---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGGVSTGVG----------VGSHVGGGISESLGGSGSVGGSTAVGGGAH
MAV_4827|M.avium_104 VPTP-----------------GAGTPGGSGGGHLPFPGAGS---------
Mflv_5091|M.gilvum_PYR-GCK --AQGATG-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQG
Mvan_1264|M.vanbaalenii_PYR-1 --AQGATG-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQG
MSMEG_0868|M.smegmatis_MC2_155 VMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mb1121|M.bovis_AF2122/97 FGNGGAGGGGGKGGNGAGGGLGGGSFGLPGLNG-----------------
Rv1091|M.tuberculosis_H37Rv FGNGGAGGGGGKGGNGAGGGLGGGSFGLPGLNG-----------------
MUL_1450|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4127|M.marinum_M --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TGVGGGVNTGVGVGSHVG--------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK SAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSG
Mvan_1264|M.vanbaalenii_PYR-1 SAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSE
MSMEG_0868|M.smegmatis_MC2_155 ISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVN
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mb1121|M.bovis_AF2122/97 --------SGGDGGDGGNGAPGGVLYG-------------NGGAGGQGSS
Rv1091|M.tuberculosis_H37Rv --------SGGDGGDGGNGAPGGVLYG-------------NGGAGGQGSS
MUL_1450|M.ulcerans_Agy99 --------SGGAGGDGGS--------------------------------
MMAR_4127|M.marinum_M --------GGGSGGSGANG-------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------GGISESLGGSGSVGGSTAVG----------------GGAHTS
MAV_4827|M.avium_104 -------TPGGSGGGHLP--------------------------------
Mflv_5091|M.gilvum_PYR-GCK GSG-INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE------
Mvan_1264|M.vanbaalenii_PYR-1 AVD-INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE------
MSMEG_0868|M.smegmatis_MC2_155 GTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGN
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mb1121|M.bovis_AF2122/97 GGIGGPGATGGAGG-----------KGGDGGDAQLIGDGGNGGN------
Rv1091|M.tuberculosis_H37Rv GGIGGPGATGGAGG-----------KGGDGGDAQLIGDGGNGGN------
MUL_1450|M.ulcerans_Agy99 -----PGGTGAAGG-----------AGGDGG-------------------
MMAR_4127|M.marinum_M -----FGTIGGTGG-----------SGGRGGDARLIGNGGDGGA------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AINDALGGSGSVGG----------STAVGGGAHTSAINESMNSSINASHS
MAV_4827|M.avium_104 -----TPGAGTPGG----------GLGGFGGGHAPAPGGGLGGG------
Mflv_5091|M.gilvum_PYR-GCK --GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 --GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu ------------------------------------------------
Mb1121|M.bovis_AF2122/97 --GGAGGTGGTPGPGGPGGSGGLGGLLFGQTGTAGVSP----------
Rv1091|M.tuberculosis_H37Rv --GGAGGTGGTPGPGGPGGSGGLGGLLFGQTGTAGVSP----------
MUL_1450|M.ulcerans_Agy99 ------QRGGSPG----------------APGAAGV------------
MMAR_4127|M.marinum_M --GAPGGNSAPPGDGGVGGAG---GTLSGTPGATGASG----------
MLBr_01183|M.leprae_Br4923 ------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SSMNESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH---
MAV_4827|M.avium_104 -----GGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK------------