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MRVVRLFAAVLTILTAGLLWATPVGAQPPTKLTDHLTDSNRVLTDPDRAAVSSAIDRLYRDRHIQLWVVY VDNFNKFKPDNWADRTRSESGMGDRDVLLAVATNTKLFTLNPPPQLQNPTADELNSLRTNKIGPAVSAKN WAIAAIAAADGLDTSLSVSHPASPAKRAWLPIAIAVIAVVVVVVVLLLVLYRARRRRRAARGVGPGGPQD RSLGEALSTAEARLRQISDYVARHHDSVGADARSRLDEATRHLAAAHAKQASNDTEAIAHANRASTLAAE AQHLANDDVLGAHRTTRRRGAASKR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2102 | - | - | 100% (305) | hypothetical protein MAV_2102 |
| M. avium 104 | MAV_2041 | - | 2e-40 | 44.88% (205) | hypothetical protein MAV_2041 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2374 | - | 8e-40 | 34.38% (288) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_2720 | - | 3e-33 | 31.29% (294) | hypothetical protein Mflv_2720 |
| M. tuberculosis H37Rv | Rv2345 | - | 8e-40 | 34.38% (288) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1706c | - | 2e-31 | 37.85% (214) | hypothetical protein MAB_1706c |
| M. marinum M | MMAR_3652 | - | 2e-39 | 41.90% (210) | hypothetical protein MMAR_3652 |
| M. smegmatis MC2 155 | MSMEG_4484 | - | 2e-36 | 35.35% (297) | putative transmembrane protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3816 | - | 8e-31 | 31.06% (293) | hypothetical protein Mvan_3816 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2374|M.bovis_AF2122/97 ---MRLVR----LLGMVLTILAAGLLLGPPAGAQPPFRLSNYVTDNAGVL
Rv2345|M.tuberculosis_H37Rv ---MRLVR----LLGMVLTILAAGLLLGPPAGAQPPFRLSNYVTDNAGVL
MMAR_3652|M.marinum_M ---MRIPR----LLGVILMIFTTGLLLAPPSGAQPPFRLASYVTDNADAL
Mflv_2720|M.gilvum_PYR-GCK ---MRVAR----LLPLLLALLTVGLLGAPAASAEPPLRLPTYLTDRAGAL
Mvan_3816|M.vanbaalenii_PYR-1 MAVMRVAR----LLPMLLAVLTLGLLCAPGVAAEPPLRLPTYLTDNAGAL
MSMEG_4484|M.smegmatis_MC2_155 ---MRIGR----LFSLLLAILTTGLLVAPAAAAEPPLRLATQITDQAGAL
MAB_1706c|M.abscessus_ATCC_199 ---MRLLRALAGLLGVLIAVCAPTLLLAPVASADPPFRIPGYVTDRAGAL
MAV_2102|M.avium_104 ---MRVVR----LFAAVLTILTAGLLWATPVGAQPPTKLTDHLTDSNRVL
**: * *: :: : : ** .. .*:** ::. :** .*
Mb2374|M.bovis_AF2122/97 TSSGRTAVTAAVDRLYADRRIRLWVVYVENFSGQSALNWAQRTTRTSELG
Rv2345|M.tuberculosis_H37Rv TSSGRTAVTAAVDRLYADRRIRLWVVYVENFSGQSALNWAQRTTRTSELG
MMAR_3652|M.marinum_M TSSGRAKVTTAVNQLYTERHVRLWVVYVDDFSGQSATNWAQRTMQTSELG
Mflv_2720|M.gilvum_PYR-GCK DAAGESEVQTAIDQLYDDKRIRLWVVYVEDFSGQSAQTWAQTTFTRSDLG
Mvan_3816|M.vanbaalenii_PYR-1 DTAGTAEVQAAIDRLYNEERIRLWVVFVDDFSGQDAQTWTQTTFARSDLG
MSMEG_4484|M.smegmatis_MC2_155 SASQAASVQRALDRLYDDRRIKLWVVFVEDFSGQNYIGWAQNTMRLSDFG
MAB_1706c|M.abscessus_ATCC_199 KN--PAKVRAAVDQLYDQQHVRLWVVYVKDFEGTDPTAWADKTIKASNLG
MAV_2102|M.avium_104 TDPDRAAVSSAIDRLYRDRHIQLWVVYVDNFNKFKPDNWADRTRSESGMG
: * *:::** :.:::****:*.:*. . *:: * * :*
Mb2374|M.bovis_AF2122/97 NYDALLAVATTGREYAFLVPSAMPGVSEGQVDNVRRYQIEPALHDGDYSG
Rv2345|M.tuberculosis_H37Rv NYDALLAVATTGREYAFLVPSAMPGVSEGQVDNVRRYQIEPALHDGDYSG
MMAR_3652|M.marinum_M DYDAILAVATVARSYAFLVPSTVDGITSSQVESLRRNKIEPKLRDGDWAG
Mflv_2720|M.gilvum_PYR-GCK DQDVILAVATVDRAYALITPRGG--AVRADIDEVRTQQVEPRLRAGDWAG
Mvan_3816|M.vanbaalenii_PYR-1 NQDVILAVATVDRAYALIAPKGG--AVRVDIDKVRTQQVEPLLRTGDWAG
MSMEG_4484|M.smegmatis_MC2_155 DDDALLAVATVDRAFAFQVPDTL--VDTARADDIRRNSIGPSLRREDWAG
MAB_1706c|M.abscessus_ATCC_199 DRDALLAVATEERSYAFQVASGIKNVSDSEIENLRTNTIEPALRTSDWDG
MAV_2102|M.avium_104 DRDVLLAVATNTKLFTLNPPPQLQNPTADELNSLRTNKIGPAVSAKNWAI
: *.:***** : ::: . :.:* : * : ::
Mb2374|M.bovis_AF2122/97 AAVAAANGLNRSPSSSSR------VVLLVTVGIIVIVVAVLLVVMRHRNR
Rv2345|M.tuberculosis_H37Rv AAVAAANGLNRSPSSSSR------VVLLVTVGIIVIVVAVLLVVMRHRNR
MMAR_3652|M.marinum_M AAVAAADGLNKSPRPSGG------IPLLVVLSVLAVAVAIFWIVMRYRAS
Mflv_2720|M.gilvum_PYR-GCK AAVAAAQGL----AGSGGGS-VSWFGVIVALALIALALTILVLWQRRRRR
Mvan_3816|M.vanbaalenii_PYR-1 AAVAAAEGL----AGSGGGS-VSWTGVLVVLAVIALALAALVLWQRRRRR
MSMEG_4484|M.smegmatis_MC2_155 AAIAAADQLNTEPASATGGG-VSWPALLIVLGIIAVLIGILWIWSRRRRA
MAB_1706c|M.abscessus_ATCC_199 AAIKTATGLESAASSSAS---IPWKPVLGALAFGAVLVGAFMLFSWFRTR
MAV_2102|M.avium_104 AAIAAADGLDTSLSVSHPASPAKRAWLPIAIAVIAVVVVVVVLLLVLYRA
**: :* * : : .:.. .: : . :
Mb2374|M.bovis_AF2122/97 RRRADELAAARRVDPTNVMALAAVPLQALDDLSRSMVVDVDNAVRTSTNE
Rv2345|M.tuberculosis_H37Rv RRRADELAAARRVDPTNVMALAAVPLQALDDLSRSMVVDVDNAVRTSTNE
MMAR_3652|M.marinum_M RRRTNALAAARRVDPTDARALAAVPLDVLDELSRSMVVDVDNAVRTSSNE
Mflv_2720|M.gilvum_PYR-GCK KRREAEFAAAQRVDPSDPEALAAVPLDALDDLSRKIVVDVDNEVRTSESE
Mvan_3816|M.vanbaalenii_PYR-1 KRREAEFAAAQRVDPSDANALAAVPLDALDELSRKIVVDVDNELRTSESE
MSMEG_4484|M.smegmatis_MC2_155 KRRKAEFEAAKRVDPTDPDALASVPLEALDALSREIVVDVDNAVRTSQAE
MAB_1706c|M.abscessus_ATCC_199 SRRRAEIEAAKGIDPSDAEALAKQPVTALDGLSKSIVVNVDNAVRTSEAE
MAV_2102|M.avium_104 RRRR---RAARGVGPG----------------------------------
** **: :.*
Mb2374|M.bovis_AF2122/97 LALAIEEFGERRTAPFTQAVNNAKAALSQAFTVRQQLDDNTPETPAQRRE
Rv2345|M.tuberculosis_H37Rv LALAIEEFGERRTAPFTQAVNNAKAALSQAFTVRQQLDDNTPETPAQRRE
MMAR_3652|M.marinum_M LAVAIDEFGEQRTAPFSQAVSNAKAALSQAFSVRQQLDDSTPETPAQRRD
Mflv_2720|M.gilvum_PYR-GCK LALAVEEFGAQDTAAFTRAVEGAKTTLAQALNVRHILDDAVPETPMQRRD
Mvan_3816|M.vanbaalenii_PYR-1 LALAVEEFGEQDTAPFSRAVANARTTLAQALNVRQILDDAVPETPMQRRD
MSMEG_4484|M.smegmatis_MC2_155 LELAVEEFGAKRTEPFTTAVANARKALAQAFNVRQILDDDVPETPLQQRD
MAB_1706c|M.abscessus_ATCC_199 LALAVEEFGTESTAPFQQAVDSAKKALAQAFSVRKQLDDAIPETPLEQRR
MAV_2102|M.avium_104 --------------------------------------------------
Mb2374|M.bovis_AF2122/97 LLTRVIVSAAHADRELASQTEAFEKLRDLVINAPARLDLLTQQYVELTTR
Rv2345|M.tuberculosis_H37Rv LLTRVIVSAAHADRELASQTEAFEKLRDLVINAPARLDLLTQQYVELTTR
MMAR_3652|M.marinum_M LLTRVIVSAANADRELESQTEAFEKLRDLVINAPARLDLLTQRYIELTTR
Mflv_2720|M.gilvum_PYR-GCK LLTRVIVAAAKADQELEAQREAFAALRDLVINAPSRLDTLTQQMIDLTTR
Mvan_3816|M.vanbaalenii_PYR-1 LLTRVIVAAAKADRELEAQREAFAQLRDLLINAPSRLDTLTQQMVDLTAR
MSMEG_4484|M.smegmatis_MC2_155 LLTRVIVSAARADRELEAQSAAFEQLRDLVINAPARLDLMTQQMVDLSAR
MAB_1706c|M.abscessus_ATCC_199 LLIDVITTAARADRTLEDQSSAFDALRNLVINAPAKLDTLTQQVVAVTAR
MAV_2102|M.avium_104 --------------------------------------------------
Mb2374|M.bovis_AF2122/97 IGPTQQRLAELHTEFDAAAMTSIAGNVTTATERLAFADRNISAARDLADQ
Rv2345|M.tuberculosis_H37Rv IGPTQQRLAELHTEFDAAAMTSIAGNVTTATERLAFADRNISAARDLADQ
MMAR_3652|M.marinum_M IAPTEQRLVELHDEFGATALSSISANVASAHELLAFADSNISSARELSAK
Mflv_2720|M.gilvum_PYR-GCK ITPAEQTLQQLKSQFAASALVSVSDNIDEARSRLAYADQSITTARTLVSR
Mvan_3816|M.vanbaalenii_PYR-1 LTPAEQTLEQLKSQFAETALVSVSDNIDEARQRLAFADQSITTARGLVSR
MSMEG_4484|M.smegmatis_MC2_155 IETSQQTLAALHTQFDARALESVAGNVDTARERLAFADRNITTARGLVSR
MAB_1706c|M.abscessus_ATCC_199 LPESERILGQLRTEFDAAALASIGDNVAEATERVRFADSRITHGRELAAR
MAV_2102|M.avium_104 --------------------------------------------------
Mb2374|M.bovis_AF2122/97 AVSGRQAGLVDAVRAAESALGQARALLDAVDSAATDIRHAVASLPAVVAD
Rv2345|M.tuberculosis_H37Rv AVSGRQAGLVDAVRAAESALGQARALLDAVDSAATDIRHAVASLPAVVAD
MMAR_3652|M.marinum_M AVSGQQTGLVDAVRAAESALGQARSLLDAVDSAAGDIRHAVATMPSVLAD
Mflv_2720|M.gilvum_PYR-GCK PAH-RQGGLVDAIHSAEAALGQARTLLDAVDSASTDINRAVTGLPAVIAD
Mvan_3816|M.vanbaalenii_PYR-1 PAD-RQGGLVDAIHAAEAALGQARTLLDAVDSASTDINRAVTGLPAVIAD
MSMEG_4484|M.smegmatis_MC2_155 PAA-DQTGLVDAVRAAESALSQARTLLDAVDSASTDINRALAGLPAAVAD
MAB_1706c|M.abscessus_ATCC_199 ALEGQQMSLVDAIRGAESALTQANALLDAIDNAANNIRHAIDSLAASIAD
MAV_2102|M.avium_104 --------------------------------------------------
Mb2374|M.bovis_AF2122/97 IQTGIKRANQHLQQAQQPQTGRTGDLIAARDAAARALDRAR--GAADPLT
Rv2345|M.tuberculosis_H37Rv IQTGIKRANQHLQQAQQPQTGRTGDLIAARDAAARALDRAR--GAADPLT
MMAR_3652|M.marinum_M IQAGIQHANEQLQKSPANKSAYAAELIAARDAAARAVDNARVTGAADPLS
Mflv_2720|M.gilvum_PYR-GCK IQNGINSAGAQLAQG---SVAVATELSDARDAAVQAVAEAQSSGETDPLG
Mvan_3816|M.vanbaalenii_PYR-1 IQNGINQAGAQLAQG---NVAVATELSTARDAAVQAVSQAQSTGNSDPLG
MSMEG_4484|M.smegmatis_MC2_155 IEAGIEQANDLLAQP---DTPQADKLATARDAAVQAAGEAKSNGTADPLG
MAB_1706c|M.abscessus_ATCC_199 TKSDIAQAEEFQKQG---RLPSSEELTKAHDAAVAAVADAERIGATDPLT
MAV_2102|M.avium_104 --------------------------------GPQD--------------
.
Mb2374|M.bovis_AF2122/97 AFDQLTKVDADLDRLLATLAEEQATADRLNRSLEQALFTAESRVRAVSEY
Rv2345|M.tuberculosis_H37Rv AFDQLTKVDADLDRLLATLAEEQATADRLNRSLEQALFTAESRVRAVSEY
MMAR_3652|M.marinum_M AFAQLTTADADLDRLLAAIAQEQANAEHLRRSLEQALFTAESRIRAVSDY
Mflv_2720|M.gilvum_PYR-GCK AFTRLTQADADLDRLLAEVAEERETAARLSRTFDQALFNAQSRVRAVSDY
Mvan_3816|M.vanbaalenii_PYR-1 AFTRLTQADADLDRLLAEVAEERETAERLSRTFDQALFNAQSRVRAVSDY
MSMEG_4484|M.smegmatis_MC2_155 TFTRLTQADADLDQLLATVHEQREAAERLARTLEQAIFTAESRITAVSDY
MAB_1706c|M.abscessus_ATCC_199 AFTHLAAADAQLDKLLAAAQEERAAAERRARVLDQALVAARQRLDAVNQY
MAV_2102|M.avium_104 ------------------------------RSLGEALSTAEARLRQISDY
* : :*: *. *: :.:*
Mb2374|M.bovis_AF2122/97 IDTRRGSIGPEARTRLAEAKRQLEAAHDRKSSNPTEAIAYANAASTLAAH
Rv2345|M.tuberculosis_H37Rv IDTRRGSIGPEARTRLAEAKRQLEAAHDRKSSNPTEAIAYANAASTLAAH
MMAR_3652|M.marinum_M IDTRRGSIGPEARTRLAEAGRRLDAAQSYRSTNPTEAIAQANAASTLAAN
Mflv_2720|M.gilvum_PYR-GCK IDTRRGAIGPEARTRLAEAVRQLQAARDKQDTNLNEAIAHANGAAMLAAQ
Mvan_3816|M.vanbaalenii_PYR-1 IDTRRGAIGPEARTRLAEAVRQLQAARDKRETNLNEAIAHANGAAMLAAQ
MSMEG_4484|M.smegmatis_MC2_155 IETRRGSIGPEARTRLAEATRQLEAARAKRSTNPNEAVAHANGASTLAAQ
MAB_1706c|M.abscessus_ATCC_199 IGLHRGAVGARTRWNLDEAQRRLAAAEQSRASNPSDAILFANGAAELATQ
MAV_2102|M.avium_104 VARHHDSVGADARSRLDEATRHLAAAHAKQASNDTEAIAHANRASTLAAE
: ::.::*. :* .* ** *:* **. : :* .:*: ** *: **:.
Mb2374|M.bovis_AF2122/97 AQSLANADVQSAQRAYTR---RGGNN--AGAILGGIIIGDLLSGGTRGGL
Rv2345|M.tuberculosis_H37Rv AQSLANADVQSAQRAYTR---RGGNN--AGAILGGIIIGDLLSGGTRGGL
MMAR_3652|M.marinum_M AQSLANSDVQAAQRAYTR---QGGNN--TGAVLGGIIIGDLLSGGMRGGF
Mflv_2720|M.gilvum_PYR-GCK AQSLANSDVTAAQRHFNGPYGGGGGGGQMGAVIGGILIGNVLSGVLRGGL
Mvan_3816|M.vanbaalenii_PYR-1 AQSLANSDVTAAQRHFSGPYGGGGGG-QMGAVIGGILIGNVLSGALRGGF
MSMEG_4484|M.smegmatis_MC2_155 AQSLANDDVRAAQRSYTSHHGGGGAD--MGAVLGGIIIGNVLRGGFGGGG
MAB_1706c|M.abscessus_ATCC_199 AQYSAQQEVQSAQRYYGNGYGGYSVAGDVAGNVAGAVIGGILRGMLSGGA
MAV_2102|M.avium_104 AQHLANDDVLGAHRTTRR------------------------RGAASKR-
** *: :* .*:* *
Mb2374|M.bovis_AF2122/97 G-GWIPTSFGGSSNAPGSS---------------PDGGFLGGGGRF
Rv2345|M.tuberculosis_H37Rv G-GWIPTSFGGSSNAPGSS---------------PDGGFLGGGGRF
MMAR_3652|M.marinum_M G-GWSPTSFGGSSGSSGDS---------------SGGGFLGGGGRF
Mflv_2720|M.gilvum_PYR-GCK GGGGFGGGFG--GGGFGGG---------------GGGGFSGGGGRF
Mvan_3816|M.vanbaalenii_PYR-1 GGGGFGGGFG--GGGFGGG---------------GGG-FSGGGGRF
MSMEG_4484|M.smegmatis_MC2_155 GYGGYGGGFGGFGGGFGGGRSSGRPTSYGGSSHSSGRNYGGGGGRF
MAB_1706c|M.abscessus_ATCC_199 GHHSSWSGSG--SSSYGGS------------SRSSGSSFRGGGGRF
MAV_2102|M.avium_104 ----------------------------------------------