For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_4484 (-)

annotation: putative transmembrane protein
coordinates: 4565431 - 4567473
length: 680

MRIGRLFSLLLAILTTGLLVAPAAAAEPPLRLATQITDQAGALSASQAASVQRALDRLYDDRRIKLWVVF
VEDFSGQNYIGWAQNTMRLSDFGDDDALLAVATVDRAFAFQVPDTLVDTARADDIRRNSIGPSLRREDWA
GAAIAAADQLNTEPASATGGGVSWPALLIVLGIIAVLIGILWIWSRRRRAKRRKAEFEAAKRVDPTDPDA
LASVPLEALDALSREIVVDVDNAVRTSQAELELAVEEFGAKRTEPFTTAVANARKALAQAFNVRQILDDD
VPETPLQQRDLLTRVIVSAARADRELEAQSAAFEQLRDLVINAPARLDLMTQQMVDLSARIETSQQTLAA
LHTQFDARALESVAGNVDTARERLAFADRNITTARGLVSRPAADQTGLVDAVRAAESALSQARTLLDAVD
SASTDINRALAGLPAAVADIEAGIEQANDLLAQPDTPQADKLATARDAAVQAAGEAKSNGTADPLGTFTR
LTQADADLDQLLATVHEQREAAERLARTLEQAIFTAESRITAVSDYIETRRGSIGPEARTRLAEATRQLE
AARAKRSTNPNEAVAHANGASTLAAQAQSLANDDVRAAQRSYTSHHGGGGADMGAVLGGIIIGNVLRGGF
GGGGGYGGYGGGFGGFGGGFGGGRSSGRPTSYGGSSHSSGRNYGGGGGRF
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4484--100% (680)putative transmembrane protein
M. smegmatis MC2 155MSMEG_0868-1e-0640.24% (82) hypothetical protein MSMEG_0868
M. smegmatis MC2 155MSMEG_3202-2e-0636.78% (87) hypothetical protein MSMEG_3202

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2374-0.057.97% (690) transmembrane protein
M. gilvum PYR-GCKMflv_2720-0.063.49% (682) hypothetical protein Mflv_2720
M. tuberculosis H37RvRv2345-0.057.97% (690) transmembrane protein
M. leprae Br4923MLBr_01556infB4e-0544.44% (72) translation initiation factor IF-2
M. abscessus ATCC 19977MAB_1706c-1e-16948.38% (680) hypothetical protein MAB_1706c
M. marinum MMMAR_3652-0.057.68% (690) hypothetical protein MMAR_3652
M. avium 104MAV_2041-0.058.06% (689) hypothetical protein MAV_2041
M. thermoresistible (build 8)TH_1853-3e-0624.02% (533) conserved hypothetical protein
M. ulcerans Agy99MUL_4399-3e-0940.43% (94) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_3816-0.064.02% (681) hypothetical protein Mvan_3816

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2720|M.gilvum_PYR-GCK          ----MRVARLLP-------------------LLLALLTVGL---LGAPAA
Mvan_3816|M.vanbaalenii_PYR-1       -MAVMRVARLLP-------------------MLLAVLTLGL---LCAPGV
MSMEG_4484|M.smegmatis_MC2_155      ----MRIGRLFS-------------------LLLAILTTGL---LVAPAA
Mb2374|M.bovis_AF2122/97            ----MRLVRLLG-------------------MVLTILAAGL---LLGPPA
Rv2345|M.tuberculosis_H37Rv         ----MRLVRLLG-------------------MVLTILAAGL---LLGPPA
MMAR_3652|M.marinum_M               ----MRIPRLLG-------------------VILMIFTTGL---LLAPPS
MAV_2041|M.avium_104                ----MRTARLLA-------------------VLAALLTVGLSAGLLAPPA
MAB_1706c|M.abscessus_ATCC_199      ----MRLLRALAG------------------LLGVLIAVCAPTLLLAPVA
TH_1853|M.thermoresistible__bu      ----MRLHRLALTNYRGIARREVEFPDRGVVVVSGANEIGKSSMIEALDL
MUL_4399|M.ulcerans_Agy99           -----------------------------------------------MSY
MLBr_01556|M.leprae_Br4923          MAGKARVHELAKELG-----------VTSKEVLARLNEQGEFVKSASSTV
                                                                                      

Mflv_2720|M.gilvum_PYR-GCK          SAEPPLRL--------PTYLTDRAGALDAAGESEVQTAIDQ-----LYDD
Mvan_3816|M.vanbaalenii_PYR-1       AAEPPLRL--------PTYLTDNAGALDTAGTAEVQAAIDR-----LYNE
MSMEG_4484|M.smegmatis_MC2_155      AAEPPLRL--------ATQITDQAGALSASQAASVQRALDR-----LYDD
Mb2374|M.bovis_AF2122/97            GAQPPFRL--------SNYVTDNAGVLTSSGRTAVTAAVDR-----LYAD
Rv2345|M.tuberculosis_H37Rv         GAQPPFRL--------SNYVTDNAGVLTSSGRTAVTAAVDR-----LYAD
MMAR_3652|M.marinum_M               GAQPPFRL--------ASYVTDNADALTSSGRAKVTTAVNQ-----LYTE
MAV_2041|M.avium_104                GAQPPLRL--------SDYLTDTAGVLSDSGRKAITTAVDK-----LYTD
MAB_1706c|M.abscessus_ATCC_199      SADPPFRI--------PGYVTDRAGALKNP--AKVRAAVDQ-----LYDQ
TH_1853|M.thermoresistible__bu      LFHAKDRS--------TKKEVKQVKPTHADVGAEITAEISTGPYRFVYHK
MUL_4399|M.ulcerans_Agy99           LLVAPELL--------TSAATDLEGIASALSTANLAAAVPT---------
MLBr_01556|M.leprae_Br4923          EAPVARRLRESFGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKA
                                                    .                 :   :           

Mflv_2720|M.gilvum_PYR-GCK          -------KRIRLWVVYVEDFSGQSAQTWAQTTFTRS---DLGDQDVILAV
Mvan_3816|M.vanbaalenii_PYR-1       -------ERIRLWVVFVDDFSGQDAQTWTQTTFARS---DLGNQDVILAV
MSMEG_4484|M.smegmatis_MC2_155      -------RRIKLWVVFVEDFSGQNYIGWAQNTMRLS---DFGDDDALLAV
Mb2374|M.bovis_AF2122/97            -------RRIRLWVVYVENFSGQSALNWAQRTTRTS---ELGNYDALLAV
Rv2345|M.tuberculosis_H37Rv         -------RRIRLWVVYVENFSGQSALNWAQRTTRTS---ELGNYDALLAV
MMAR_3652|M.marinum_M               -------RHVRLWVVYVDDFSGQSATNWAQRTMQTS---ELGDYDAILAV
MAV_2041|M.avium_104                -------RHIRLWVVYVDTFSGQTATRWAQDTLRTS---DLGDYDALLAV
MAB_1706c|M.abscessus_ATCC_199      -------QHVRLWVVYVKDFEGTDPTAWADKTIKAS---NLGDRDALLAV
TH_1853|M.thermoresistible__bu      RFHKKCATQLTILAPRREELSGDEAHERALAMLSETVDMELWRTQRVLQA
MUL_4399|M.ulcerans_Agy99           --------------------------------------------TGMLAA
MLBr_01556|M.leprae_Br4923          VAGNGATTAAPVQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGV
                                                                                     .

Mflv_2720|M.gilvum_PYR-GCK          ATVDRAYALITP--------------------------RGGAVRADIDEV
Mvan_3816|M.vanbaalenii_PYR-1       ATVDRAYALIAP--------------------------KGGAVRVDIDKV
MSMEG_4484|M.smegmatis_MC2_155      ATVDRAFAFQVP--------------------------DTLVDTARADDI
Mb2374|M.bovis_AF2122/97            ATTGREYAFLVPSA------------------------MPGVSEGQVDNV
Rv2345|M.tuberculosis_H37Rv         ATTGREYAFLVPSA------------------------MPGVSEGQVDNV
MMAR_3652|M.marinum_M               ATVARSYAFLVPST------------------------VDGITSSQVESL
MAV_2041|M.avium_104                ATTDRAYAFLVPPT------------------------IRGVNQSRVDAL
MAB_1706c|M.abscessus_ATCC_199      ATEERSYAFQVASG------------------------IKNVSDSEIENL
TH_1853|M.thermoresistible__bu      GSTAPVDLSGCDAL------------------------SRALDAVAGEAV
MUL_4399|M.ulcerans_Agy99           GADEVS--------------------------------------------
MLBr_01556|M.leprae_Br4923          PLPGQQGTPAAPHPGHPGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVA
                                                                                      

Mflv_2720|M.gilvum_PYR-GCK          RTQQVEPRLRA-------------GDWAGAAVAAAQGL----AGSGGGSV
Mvan_3816|M.vanbaalenii_PYR-1       RTQQVEPLLRT-------------GDWAGAAVAAAEGL----AGSGGGSV
MSMEG_4484|M.smegmatis_MC2_155      RRNSIGPSLRR-------------EDWAGAAIAAADQLNTEPASATGGGV
Mb2374|M.bovis_AF2122/97            RRYQIEPALHD-------------GDYSGAAVAAANGLN-----RSPSSS
Rv2345|M.tuberculosis_H37Rv         RRYQIEPALHD-------------GDYSGAAVAAANGLN-----RSPSSS
MMAR_3652|M.marinum_M               RRNKIEPKLRD-------------GDWAGAAVAAADGLN-----KSPRPS
MAV_2041|M.avium_104                RHNKIEPALHD-------------GDWSGAAVAAATGLD-----TAPGSS
MAB_1706c|M.abscessus_ATCC_199      RTNTIEPALRT-------------SDWDGAAIKTATGLES--AASSSASI
TH_1853|M.thermoresistible__bu      QTSGTEPLLIDRIDAEYRKYFTATGRPTGEWLAATKRLQAADEQVARCAA
MUL_4399|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01556|M.leprae_Br4923          RPIPRPPAPRPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPGAPV
                                                                                      

Mflv_2720|M.gilvum_PYR-GCK          SWFGVIVALALIALALTILVLWQ-----------RRRRRKRREAEFAAAQ
Mvan_3816|M.vanbaalenii_PYR-1       SWTGVLVVLAVIALALAALVLWQ-----------RRRRRKRREAEFAAAQ
MSMEG_4484|M.smegmatis_MC2_155      SWPALLIVLGIIAVLIGILWIWS-----------RRRRAKRRKAEFEAAK
Mb2374|M.bovis_AF2122/97            SRVVLLVTVGIIVIVVAVLLVVM-----------RHRNRRRRADELAAAR
Rv2345|M.tuberculosis_H37Rv         SRVVLLVTVGIIVIVVAVLLVVM-----------RHRNRRRRADELAAAR
MMAR_3652|M.marinum_M               GGIPLLVVLSVLAVAVAIFWIVM-----------RYRASRRRTNALAAAR
MAV_2041|M.avium_104                GRVILLATLAALLVAVMGLLLVM-----------RYRGRRRRAAALAAAR
MAB_1706c|M.abscessus_ATCC_199      PWKPVLGALAFGAVLVGAFMLFS-----------WFRTRSRRRAEIEAAK
TH_1853|M.thermoresistible__bu      RVAEVEDAVRRHATLTESLAELEDG---------RRTADAQLAAAREAAE
MUL_4399|M.ulcerans_Agy99           --AAVASLFAGYGQAYQSIS------------------------------
MLBr_01556|M.leprae_Br4923          GGRSDAGGGNYRGGGVGALPGGGSGGFRGRPGGGGHGGGGRPGQRGGAAG
                                                      :                               

Mflv_2720|M.gilvum_PYR-GCK          RVD-PSDPEALAAVPLDALDDLSRKIVVDVDN---------------EVR
Mvan_3816|M.vanbaalenii_PYR-1       RVD-PSDANALAAVPLDALDELSRKIVVDVDN---------------ELR
MSMEG_4484|M.smegmatis_MC2_155      RVD-PTDPDALASVPLEALDALSREIVVDVDN---------------AVR
Mb2374|M.bovis_AF2122/97            RVD-PTNVMALAAVPLQALDDLSRSMVVDVDN---------------AVR
Rv2345|M.tuberculosis_H37Rv         RVD-PTNVMALAAVPLQALDDLSRSMVVDVDN---------------AVR
MMAR_3652|M.marinum_M               RVD-PTDARALAAVPLDVLDELSRSMVVDVDN---------------AVR
MAV_2041|M.avium_104                RLD-PTDLDALAALPLPTLDDLSRALVVDVDN---------------ALR
MAB_1706c|M.abscessus_ATCC_199      GID-PSDAEALAKQPVTALDGLSKSIVVNVDN---------------AVR
TH_1853|M.thermoresistible__bu      AVERLTRQLAEAQLAAEAAEATHTASVAALNERRRLRAEIEERTAAVAAL
MUL_4399|M.ulcerans_Agy99           ----------------LQANAFQAQFIQAING------------------
MLBr_01556|M.leprae_Br4923          AFGRPGGAPRRGRKSKRQKRQEYDSMQAPVVG----------------GV
                                                                 :                    

Mflv_2720|M.gilvum_PYR-GCK          TSESELALAVEEFGAQDTAAFTRAVEGAKTTLAQALN--------VRHIL
Mvan_3816|M.vanbaalenii_PYR-1       TSESELALAVEEFGEQDTAPFSRAVANARTTLAQALN--------VRQIL
MSMEG_4484|M.smegmatis_MC2_155      TSQAELELAVEEFGAKRTEPFTTAVANARKALAQAFN--------VRQIL
Mb2374|M.bovis_AF2122/97            TSTNELALAIEEFGERRTAPFTQAVNNAKAALSQAFT--------VRQQL
Rv2345|M.tuberculosis_H37Rv         TSTNELALAIEEFGERRTAPFTQAVNNAKAALSQAFT--------VRQQL
MMAR_3652|M.marinum_M               TSSNELAVAIDEFGEQRTAPFSQAVSNAKAALSQAFS--------VRQQL
MAV_2041|M.avium_104                TSANELDLAVAEFGDQRTQPFTQAVTNAKAALSQAFT--------VRQQL
MAB_1706c|M.abscessus_ATCC_199      TSEAELALAVEEFGTESTAPFQQAVDSAKKALAQAFS--------VRKQL
TH_1853|M.thermoresistible__bu      QPEVDAALEAEATAREVQQEADTAAERAREAADAARERVDTARQAVQRLA
MUL_4399|M.ulcerans_Agy99           --AGGAYVAAEAASTSPLQAFEDTVLGVINAPTQTLLG--------RPLI
MLBr_01556|M.leprae_Br4923          RLPHGNGETIRLARGASLSDFAEKIDANPAALVQALFNLG-EMVTATQSV
                                                                  :   :               

Mflv_2720|M.gilvum_PYR-GCK          DDAVPETPMQRRDLLTRVIVAAAKADQELEAQREAFAALR---------D
Mvan_3816|M.vanbaalenii_PYR-1       DDAVPETPMQRRDLLTRVIVAAAKADRELEAQREAFAQLR---------D
MSMEG_4484|M.smegmatis_MC2_155      DDDVPETPLQQRDLLTRVIVSAARADRELEAQSAAFEQLR---------D
Mb2374|M.bovis_AF2122/97            DDNTPETPAQRRELLTRVIVSAAHADRELASQTEAFEKLR---------D
Rv2345|M.tuberculosis_H37Rv         DDNTPETPAQRRELLTRVIVSAAHADRELASQTEAFEKLR---------D
MMAR_3652|M.marinum_M               DDSTPETPAQRRDLLTRVIVSAANADRELESQTEAFEKLR---------D
MAV_2041|M.avium_104                DDGMPETPAQRRELLTQVIVSAARADRELESQTEAFEGLR---------D
MAB_1706c|M.abscessus_ATCC_199      DDAIPETPLEQRRLLIDVITTAARADRTLEDQSSAFDALR---------N
TH_1853|M.thermoresistible__bu      DRAERDTLADRLRRIDAAATELARVDGELATLTVTEAALRQ----IEAAE
MUL_4399|M.ulcerans_Agy99           GDGAAGTVANPNGGAGGFLYGNGGNGFSQTTAG-----------------
MLBr_01556|M.leprae_Br4923          GDETLELLGSEMNYNVQVVSPEDEDRELLEPFDLTYGEDQGDEDELQVRP
                                    .        .                                        

Mflv_2720|M.gilvum_PYR-GCK          LVINAPSRLDTLTQQMIDLTTRITPAEQTLQQLKSQFAASALVS------
Mvan_3816|M.vanbaalenii_PYR-1       LLINAPSRLDTLTQQMVDLTARLTPAEQTLEQLKSQFAETALVS------
MSMEG_4484|M.smegmatis_MC2_155      LVINAPARLDLMTQQMVDLSARIETSQQTLAALHTQFDARALES------
Mb2374|M.bovis_AF2122/97            LVINAPARLDLLTQQYVELTTRIGPTQQRLAELHTEFDAAAMTS------
Rv2345|M.tuberculosis_H37Rv         LVINAPARLDLLTQQYVELTTRIGPTQQRLAELHTEFDAAAMTS------
MMAR_3652|M.marinum_M               LVINAPARLDLLTQRYIELTTRIAPTEQRLVELHDEFGATALSS------
MAV_2041|M.avium_104                LVINAPSRLDGLTQQYVELTARIGPAEQQLAALHNEFSAAALTS------
MAB_1706c|M.abscessus_ATCC_199      LVINAPAKLDTLTQQVVAVTARLPESERILGQLRTEFDAAALAS------
TH_1853|M.thermoresistible__bu      LAVERAAGQAELASAHIELTAAVDLELRVGDEQLTIPAGGSWTAGATAPT
MUL_4399|M.ulcerans_Agy99           VAGGAGGAAGLIGNGGMGGAGGAGAAGGAGGTGGWWFGNGGVGG------
MLBr_01556|M.leprae_Br4923          PVVTVMGHVDHGKTRLLDTIRKANVREAEAGGITQHIGAYQVGVDLDGSE
                                          .         :                                 

Mflv_2720|M.gilvum_PYR-GCK          --------------------VSDNIDEARSRLAYADQSITTARTLVSRPA
Mvan_3816|M.vanbaalenii_PYR-1       --------------------VSDNIDEARQRLAFADQSITTARGLVSRPA
MSMEG_4484|M.smegmatis_MC2_155      --------------------VAGNVDTARERLAFADRNITTARGLVSRPA
Mb2374|M.bovis_AF2122/97            --------------------IAGNVTTATERLAFADRNISAARDLADQAV
Rv2345|M.tuberculosis_H37Rv         --------------------IAGNVTTATERLAFADRNISAARDLADQAV
MMAR_3652|M.marinum_M               --------------------ISANVASAHELLAFADSNISSARELSAKAV
MAV_2041|M.avium_104                --------------------VSGNVTAAKERLAFADRNIGTARELAGQAV
MAB_1706c|M.abscessus_ATCC_199      --------------------IGDNVAEATERVRFADSRITHGRELAARAL
TH_1853|M.thermoresistible__bu      EIELPGLLTARIVPGAPAAQMQETLDVARAALADALQHAGVADVASARSQ
MUL_4399|M.ulcerans_Agy99           --------------------AGGAGTAGAVGFNGVSGGAGGAGGAAGWWG
MLBr_01556|M.leprae_Br4923          R------------------LITFIDTPGHEAFTAMRARGAKATDIAILVV
                                                               .   .         .        

Mflv_2720|M.gilvum_PYR-GCK          H-RQGGLVDAIH---------SAEAALGQARTLLDAVDSASTDIN--RAV
Mvan_3816|M.vanbaalenii_PYR-1       D-RQGGLVDAIH---------AAEAALGQARTLLDAVDSASTDIN--RAV
MSMEG_4484|M.smegmatis_MC2_155      A-DQTGLVDAVR---------AAESALSQARTLLDAVDSASTDIN--RAL
Mb2374|M.bovis_AF2122/97            SGRQAGLVDAVR---------AAESALGQARALLDAVDSAATDIR--HAV
Rv2345|M.tuberculosis_H37Rv         SGRQAGLVDAVR---------AAESALGQARALLDAVDSAATDIR--HAV
MMAR_3652|M.marinum_M               SGQQTGLVDAVR---------AAESALGQARSLLDAVDSAAGDIR--HAV
MAV_2041|M.avium_104                SGQQGRLVDAVR---------AAESALGQARSLLDAVDHAAGDIR--HAI
MAB_1706c|M.abscessus_ATCC_199      EGQQMSLVDAIR---------GAESALTQANALLDAIDNAANNIR--HAI
TH_1853|M.thermoresistible__bu      VERRRELSTARETFAATVVALTGEDTLERLRARLAELDAAASDDTGELGV
MUL_4399|M.ulcerans_Agy99           AGGAGGQGGTGG----------MAGGYDNVNGVFGITAGNGGDGG-----
MLBr_01556|M.leprae_Br4923          AADDGVMPQTVEAIN---HAQAADVPIVVAVNKIDKEGADPAKIRGQLTE
                                             :                       :        .       

Mflv_2720|M.gilvum_PYR-GCK          TGLPAVIADIQNGINSAGAQLAQG---SVAVATELSDARDAAVQAVAEAQ
Mvan_3816|M.vanbaalenii_PYR-1       TGLPAVIADIQNGINQAGAQLAQG---NVAVATELSTARDAAVQAVSQAQ
MSMEG_4484|M.smegmatis_MC2_155      AGLPAAVADIEAGIEQANDLLAQP---DTPQADKLATARDAAVQAAGEAK
Mb2374|M.bovis_AF2122/97            ASLPAVVADIQTGIKRANQHLQQAQQPQTGRTGDLIAARDAAARALDRAR
Rv2345|M.tuberculosis_H37Rv         ASLPAVVADIQTGIKRANQHLQQAQQPQTGRTGDLIAARDAAARALDRAR
MMAR_3652|M.marinum_M               ATMPSVLADIQAGIQHANEQLQKSPANKSAYAAELIAARDAAARAVDNAR
MAV_2041|M.avium_104                DQLPSAMADIENDIKRAAELLAATRDTKSGHAAELAAARDAATRAVEGAR
MAB_1706c|M.abscessus_ATCC_199      DSLAASIADTKSDIAQAEEFQKQG---RLPSSEELTKAHDAAVAAVADAE
TH_1853|M.thermoresistible__bu      DDAQAELTAAERAYQQAHTDCETHRKAAVLAARRLAEKSQTAAALREKLT
MUL_4399|M.ulcerans_Agy99           -------AGGRGGWLFGDAG-------AGGQGGLGGDGNYAGQGSYGGVG
MLBr_01556|M.leprae_Br4923          YGLVAEDFGGDTMFIDISAKVGTN-IEALLEAVLLTADAALDLRANSGME
                                                                                      

Mflv_2720|M.gilvum_PYR-GCK          SS-GETDPLGAFTRLTQADADLDRLLAEVAEERETAARLSR---TFDQAL
Mvan_3816|M.vanbaalenii_PYR-1       ST-GNSDPLGAFTRLTQADADLDRLLAEVAEERETAERLSR---TFDQAL
MSMEG_4484|M.smegmatis_MC2_155      SN-GTADPLGTFTRLTQADADLDQLLATVHEQREAAERLAR---TLEQAI
Mb2374|M.bovis_AF2122/97            ---GAADPLTAFDQLTKVDADLDRLLATLAEEQATADRLNR---SLEQAL
Rv2345|M.tuberculosis_H37Rv         ---GAADPLTAFDQLTKVDADLDRLLATLAEEQATADRLNR---SLEQAL
MMAR_3652|M.marinum_M               VT-GAADPLSAFAQLTTADADLDRLLAAIAQEQANAEHLRR---SLEQAL
MAV_2041|M.avium_104                AG-APDDPLGAFGQLTKADAGLNAVLAAVAQERAAAERLAR---SLEQAL
MAB_1706c|M.abscessus_ATCC_199      RI-GATDPLTAFTHLAAADAQLDKLLAAAQEERAAAERRAR---VLDQAL
TH_1853|M.thermoresistible__bu      AARTELDTAAARLAAQRADVDDETLVVRAAAHGEEAERAAVRVAQLNAEL
MUL_4399|M.ulcerans_Agy99           GAGGAGGAAGMFGSGGSGGAGGEGGAFGDGNAGGSGS-------------
MLBr_01556|M.leprae_Br4923          AQGVAIEAHLDRGRGPVATVLVQRGTLRIGDSVVAGDAYGRVRRMVDEHG
                                           .           .  :            .              

Mflv_2720|M.gilvum_PYR-GCK          FNAQSRVRAVSDYIDTRRGAIGPEARTRLAEAVRQLQAARDKQDTNLNEA
Mvan_3816|M.vanbaalenii_PYR-1       FNAQSRVRAVSDYIDTRRGAIGPEARTRLAEAVRQLQAARDKRETNLNEA
MSMEG_4484|M.smegmatis_MC2_155      FTAESRITAVSDYIETRRGSIGPEARTRLAEATRQLEAARAKRSTNPNEA
Mb2374|M.bovis_AF2122/97            FTAESRVRAVSEYIDTRRGSIGPEARTRLAEAKRQLEAAHDRKSSNPTEA
Rv2345|M.tuberculosis_H37Rv         FTAESRVRAVSEYIDTRRGSIGPEARTRLAEAKRQLEAAHDRKSSNPTEA
MMAR_3652|M.marinum_M               FTAESRIRAVSDYIDTRRGSIGPEARTRLAEAGRRLDAAQSYRSTNPTEA
MAV_2041|M.avium_104                FTAQSRVRAVSDYIDTRRGSIGPEARTRLAEAQRHLHAAADRRATDPADA
MAB_1706c|M.abscessus_ATCC_199      VAARQRLDAVNQYIGLHRGAVGARTRWNLDEAQRRLAAAEQSRASNPSDA
TH_1853|M.thermoresistible__bu      SAAQPDQVAAALDTAARHAETVHAEHRRTADALRELNAQLEVYGSEGRKG
MUL_4399|M.ulcerans_Agy99           -GGHGGNGGNGGWLYGDAGAGGQGGNAAPGAYSDNLGTFQSSYTSGNGGA
MLBr_01556|M.leprae_Br4923          VDIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKRNA
                                       .    .         .      .                  :    .

Mflv_2720|M.gilvum_PYR-GCK          IAHANGAAMLAAQAQSLANSDVTAAQRHFNGPYGGGGGGG------QMGA
Mvan_3816|M.vanbaalenii_PYR-1       IAHANGAAMLAAQAQSLANSDVTAAQRHFSGPYGGGGGG-------QMGA
MSMEG_4484|M.smegmatis_MC2_155      VAHANGASTLAAQAQSLANDDVRAAQRSYTSHHGGGGAD--------MGA
Mb2374|M.bovis_AF2122/97            IAYANAASTLAAHAQSLANADVQSAQRAYT---RRGGNN--------AGA
Rv2345|M.tuberculosis_H37Rv         IAYANAASTLAAHAQSLANADVQSAQRAYT---RRGGNN--------AGA
MMAR_3652|M.marinum_M               IAQANAASTLAANAQSLANSDVQAAQRAYT---RQGGNN--------TGA
MAV_2041|M.avium_104                IAHANAASTLAAEAQSLANGDVQAARRAYP---RGGGGD--------MGA
MAB_1706c|M.abscessus_ATCC_199      ILFANGAAELATQAQYSAQQEVQSAQRYYG---NGYGGYS------VAGD
TH_1853|M.thermoresistible__bu      ELDAAKAEREQAEAEFLRIGRLARAVKLLRETMLRHRDASRRRYVDPFRA
MUL_4399|M.ulcerans_Agy99           GGNGGVAGMIGTGGAGGAGGAGGVNAFDSGGGGGGGGNGG-------NGG
MLBr_01556|M.leprae_Br4923          LAARSRKRISLEDLDSALKETSQLNLILKGDNAGTVEALEEALMGIQVDD
                                                                                      

Mflv_2720|M.gilvum_PYR-GCK          VIG----GILIGNVLSGVLRGGLGG----------------GGFGGGFG-
Mvan_3816|M.vanbaalenii_PYR-1       VIG----GILIGNVLSGALRGGFGG----------------GGFGGGFG-
MSMEG_4484|M.smegmatis_MC2_155      VLG----GIIIGNVLRGGFGGGGGY----------------GGYGGGFGG
Mb2374|M.bovis_AF2122/97            ILG----GIIIGDLLSGGTRGGLG-----------------GWIPTSFGG
Rv2345|M.tuberculosis_H37Rv         ILG----GIIIGDLLSGGTRGGLG-----------------GWIPTSFGG
MMAR_3652|M.marinum_M               VLG----GIIIGDLLSGGMRGGFG-----------------GWSPTSFGG
MAV_2041|M.avium_104                MLG----GIIIGDLLSSGMRGGFG-----------------GWSPASFGG
MAB_1706c|M.abscessus_ATCC_199      VAGN-VAGAVIGGILRGMLSGGAGH----------------HSSWSGSGS
TH_1853|M.thermoresistible__bu      EVER-LGRIVFGDSFEVEIDSDLCIRSRTLAGRTVDYESLSGGAKEQLGI
MUL_4399|M.ulcerans_Agy99           AGG------ASGALIEAGGVGGSGG----------------GGGAGVVGP
MLBr_01556|M.leprae_Br4923          EVALRVIDRGVGGITETNVNLASASDAIIIG--------FNVRAEGKATE
                                               *                                      

Mflv_2720|M.gilvum_PYR-GCK          -GGGFGGG----------------------------GGGGFSGGGGRF--
Mvan_3816|M.vanbaalenii_PYR-1       -GGGFGGG----------------------------GGG-FSGGGGRF--
MSMEG_4484|M.smegmatis_MC2_155      FGGGFGGGRSS-------------GRPTSYGGSSHSSGRNYGGGGGRF--
Mb2374|M.bovis_AF2122/97            SSNAPGSS----------------------------PDGGFLGGGGRF--
Rv2345|M.tuberculosis_H37Rv         SSNAPGSS----------------------------PDGGFLGGGGRF--
MMAR_3652|M.marinum_M               SSGSSGDS----------------------------SGGGFLGGGGRF--
MAV_2041|M.avium_104                STSSSG--------------------------------GGVLGGGGRF--
MAB_1706c|M.abscessus_ATCC_199      SSYGGSSR---------------------------SSGSSFRGGGGRF--
TH_1853|M.thermoresistible__bu      VARLAGAALVARDDTVPVVIDDALGFTDAERLVKMGAVFDAVGGDGQVIV
MUL_4399|M.ulcerans_Agy99           PAGNPGND----------------------------GLDGVTGASGLLFG
MLBr_01556|M.leprae_Br4923          LASREGVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQLGRAEIRALFRS
                                         .                                       . .  

Mflv_2720|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3816|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4484|M.smegmatis_MC2_155      --------------------------------------------------
Mb2374|M.bovis_AF2122/97            --------------------------------------------------
Rv2345|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_3652|M.marinum_M               --------------------------------------------------
MAV_2041|M.avium_104                --------------------------------------------------
MAB_1706c|M.abscessus_ATCC_199      --------------------------------------------------
TH_1853|M.thermoresistible__bu      LTCSPDRYAGISDAHRIELTA-----------------------------
MUL_4399|M.ulcerans_Agy99           G-------------------------------------------------
MLBr_01556|M.leprae_Br4923          SKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTSLRREKDDVTEV
                                                                                      

Mflv_2720|M.gilvum_PYR-GCK          --------------------------------
Mvan_3816|M.vanbaalenii_PYR-1       --------------------------------
MSMEG_4484|M.smegmatis_MC2_155      --------------------------------
Mb2374|M.bovis_AF2122/97            --------------------------------
Rv2345|M.tuberculosis_H37Rv         --------------------------------
MMAR_3652|M.marinum_M               --------------------------------
MAV_2041|M.avium_104                --------------------------------
MAB_1706c|M.abscessus_ATCC_199      --------------------------------
TH_1853|M.thermoresistible__bu      --------------------------------
MUL_4399|M.ulcerans_Agy99           --------------------------------
MLBr_01556|M.leprae_Br4923          REGFECGMTLGYSDIKEGDVIESYELVEKQRA