For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MRIGRLFSLLLAILTTGLLVAPAAAAEPPLRLATQITDQAGALSASQAASVQRALDRLYDDRRIKLWVVF VEDFSGQNYIGWAQNTMRLSDFGDDDALLAVATVDRAFAFQVPDTLVDTARADDIRRNSIGPSLRREDWA GAAIAAADQLNTEPASATGGGVSWPALLIVLGIIAVLIGILWIWSRRRRAKRRKAEFEAAKRVDPTDPDA LASVPLEALDALSREIVVDVDNAVRTSQAELELAVEEFGAKRTEPFTTAVANARKALAQAFNVRQILDDD VPETPLQQRDLLTRVIVSAARADRELEAQSAAFEQLRDLVINAPARLDLMTQQMVDLSARIETSQQTLAA LHTQFDARALESVAGNVDTARERLAFADRNITTARGLVSRPAADQTGLVDAVRAAESALSQARTLLDAVD SASTDINRALAGLPAAVADIEAGIEQANDLLAQPDTPQADKLATARDAAVQAAGEAKSNGTADPLGTFTR LTQADADLDQLLATVHEQREAAERLARTLEQAIFTAESRITAVSDYIETRRGSIGPEARTRLAEATRQLE AARAKRSTNPNEAVAHANGASTLAAQAQSLANDDVRAAQRSYTSHHGGGGADMGAVLGGIIIGNVLRGGF GGGGGYGGYGGGFGGFGGGFGGGRSSGRPTSYGGSSHSSGRNYGGGGGRF
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_4484 | - | - | 100% (680) | putative transmembrane protein |
M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-06 | 40.24% (82) | hypothetical protein MSMEG_0868 |
M. smegmatis MC2 155 | MSMEG_3202 | - | 2e-06 | 36.78% (87) | hypothetical protein MSMEG_3202 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2374 | - | 0.0 | 57.97% (690) | transmembrane protein |
M. gilvum PYR-GCK | Mflv_2720 | - | 0.0 | 63.49% (682) | hypothetical protein Mflv_2720 |
M. tuberculosis H37Rv | Rv2345 | - | 0.0 | 57.97% (690) | transmembrane protein |
M. leprae Br4923 | MLBr_01556 | infB | 4e-05 | 44.44% (72) | translation initiation factor IF-2 |
M. abscessus ATCC 19977 | MAB_1706c | - | 1e-169 | 48.38% (680) | hypothetical protein MAB_1706c |
M. marinum M | MMAR_3652 | - | 0.0 | 57.68% (690) | hypothetical protein MMAR_3652 |
M. avium 104 | MAV_2041 | - | 0.0 | 58.06% (689) | hypothetical protein MAV_2041 |
M. thermoresistible (build 8) | TH_1853 | - | 3e-06 | 24.02% (533) | conserved hypothetical protein |
M. ulcerans Agy99 | MUL_4399 | - | 3e-09 | 40.43% (94) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_3816 | - | 0.0 | 64.02% (681) | hypothetical protein Mvan_3816 |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_2720|M.gilvum_PYR-GCK ----MRVARLLP-------------------LLLALLTVGL---LGAPAA Mvan_3816|M.vanbaalenii_PYR-1 -MAVMRVARLLP-------------------MLLAVLTLGL---LCAPGV MSMEG_4484|M.smegmatis_MC2_155 ----MRIGRLFS-------------------LLLAILTTGL---LVAPAA Mb2374|M.bovis_AF2122/97 ----MRLVRLLG-------------------MVLTILAAGL---LLGPPA Rv2345|M.tuberculosis_H37Rv ----MRLVRLLG-------------------MVLTILAAGL---LLGPPA MMAR_3652|M.marinum_M ----MRIPRLLG-------------------VILMIFTTGL---LLAPPS MAV_2041|M.avium_104 ----MRTARLLA-------------------VLAALLTVGLSAGLLAPPA MAB_1706c|M.abscessus_ATCC_199 ----MRLLRALAG------------------LLGVLIAVCAPTLLLAPVA TH_1853|M.thermoresistible__bu ----MRLHRLALTNYRGIARREVEFPDRGVVVVSGANEIGKSSMIEALDL MUL_4399|M.ulcerans_Agy99 -----------------------------------------------MSY MLBr_01556|M.leprae_Br4923 MAGKARVHELAKELG-----------VTSKEVLARLNEQGEFVKSASSTV Mflv_2720|M.gilvum_PYR-GCK SAEPPLRL--------PTYLTDRAGALDAAGESEVQTAIDQ-----LYDD Mvan_3816|M.vanbaalenii_PYR-1 AAEPPLRL--------PTYLTDNAGALDTAGTAEVQAAIDR-----LYNE MSMEG_4484|M.smegmatis_MC2_155 AAEPPLRL--------ATQITDQAGALSASQAASVQRALDR-----LYDD Mb2374|M.bovis_AF2122/97 GAQPPFRL--------SNYVTDNAGVLTSSGRTAVTAAVDR-----LYAD Rv2345|M.tuberculosis_H37Rv GAQPPFRL--------SNYVTDNAGVLTSSGRTAVTAAVDR-----LYAD MMAR_3652|M.marinum_M GAQPPFRL--------ASYVTDNADALTSSGRAKVTTAVNQ-----LYTE MAV_2041|M.avium_104 GAQPPLRL--------SDYLTDTAGVLSDSGRKAITTAVDK-----LYTD MAB_1706c|M.abscessus_ATCC_199 SADPPFRI--------PGYVTDRAGALKNP--AKVRAAVDQ-----LYDQ TH_1853|M.thermoresistible__bu LFHAKDRS--------TKKEVKQVKPTHADVGAEITAEISTGPYRFVYHK MUL_4399|M.ulcerans_Agy99 LLVAPELL--------TSAATDLEGIASALSTANLAAAVPT--------- MLBr_01556|M.leprae_Br4923 EAPVARRLRESFGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKA . : : Mflv_2720|M.gilvum_PYR-GCK -------KRIRLWVVYVEDFSGQSAQTWAQTTFTRS---DLGDQDVILAV Mvan_3816|M.vanbaalenii_PYR-1 -------ERIRLWVVFVDDFSGQDAQTWTQTTFARS---DLGNQDVILAV MSMEG_4484|M.smegmatis_MC2_155 -------RRIKLWVVFVEDFSGQNYIGWAQNTMRLS---DFGDDDALLAV Mb2374|M.bovis_AF2122/97 -------RRIRLWVVYVENFSGQSALNWAQRTTRTS---ELGNYDALLAV Rv2345|M.tuberculosis_H37Rv -------RRIRLWVVYVENFSGQSALNWAQRTTRTS---ELGNYDALLAV MMAR_3652|M.marinum_M -------RHVRLWVVYVDDFSGQSATNWAQRTMQTS---ELGDYDAILAV MAV_2041|M.avium_104 -------RHIRLWVVYVDTFSGQTATRWAQDTLRTS---DLGDYDALLAV MAB_1706c|M.abscessus_ATCC_199 -------QHVRLWVVYVKDFEGTDPTAWADKTIKAS---NLGDRDALLAV TH_1853|M.thermoresistible__bu RFHKKCATQLTILAPRREELSGDEAHERALAMLSETVDMELWRTQRVLQA MUL_4399|M.ulcerans_Agy99 --------------------------------------------TGMLAA MLBr_01556|M.leprae_Br4923 VAGNGATTAAPVQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGV . Mflv_2720|M.gilvum_PYR-GCK ATVDRAYALITP--------------------------RGGAVRADIDEV Mvan_3816|M.vanbaalenii_PYR-1 ATVDRAYALIAP--------------------------KGGAVRVDIDKV MSMEG_4484|M.smegmatis_MC2_155 ATVDRAFAFQVP--------------------------DTLVDTARADDI Mb2374|M.bovis_AF2122/97 ATTGREYAFLVPSA------------------------MPGVSEGQVDNV Rv2345|M.tuberculosis_H37Rv ATTGREYAFLVPSA------------------------MPGVSEGQVDNV MMAR_3652|M.marinum_M ATVARSYAFLVPST------------------------VDGITSSQVESL MAV_2041|M.avium_104 ATTDRAYAFLVPPT------------------------IRGVNQSRVDAL MAB_1706c|M.abscessus_ATCC_199 ATEERSYAFQVASG------------------------IKNVSDSEIENL TH_1853|M.thermoresistible__bu GSTAPVDLSGCDAL------------------------SRALDAVAGEAV MUL_4399|M.ulcerans_Agy99 GADEVS-------------------------------------------- MLBr_01556|M.leprae_Br4923 PLPGQQGTPAAPHPGHPGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVA Mflv_2720|M.gilvum_PYR-GCK RTQQVEPRLRA-------------GDWAGAAVAAAQGL----AGSGGGSV Mvan_3816|M.vanbaalenii_PYR-1 RTQQVEPLLRT-------------GDWAGAAVAAAEGL----AGSGGGSV MSMEG_4484|M.smegmatis_MC2_155 RRNSIGPSLRR-------------EDWAGAAIAAADQLNTEPASATGGGV Mb2374|M.bovis_AF2122/97 RRYQIEPALHD-------------GDYSGAAVAAANGLN-----RSPSSS Rv2345|M.tuberculosis_H37Rv RRYQIEPALHD-------------GDYSGAAVAAANGLN-----RSPSSS MMAR_3652|M.marinum_M RRNKIEPKLRD-------------GDWAGAAVAAADGLN-----KSPRPS MAV_2041|M.avium_104 RHNKIEPALHD-------------GDWSGAAVAAATGLD-----TAPGSS MAB_1706c|M.abscessus_ATCC_199 RTNTIEPALRT-------------SDWDGAAIKTATGLES--AASSSASI TH_1853|M.thermoresistible__bu QTSGTEPLLIDRIDAEYRKYFTATGRPTGEWLAATKRLQAADEQVARCAA MUL_4399|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 RPIPRPPAPRPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPGAPV Mflv_2720|M.gilvum_PYR-GCK SWFGVIVALALIALALTILVLWQ-----------RRRRRKRREAEFAAAQ Mvan_3816|M.vanbaalenii_PYR-1 SWTGVLVVLAVIALALAALVLWQ-----------RRRRRKRREAEFAAAQ MSMEG_4484|M.smegmatis_MC2_155 SWPALLIVLGIIAVLIGILWIWS-----------RRRRAKRRKAEFEAAK Mb2374|M.bovis_AF2122/97 SRVVLLVTVGIIVIVVAVLLVVM-----------RHRNRRRRADELAAAR Rv2345|M.tuberculosis_H37Rv SRVVLLVTVGIIVIVVAVLLVVM-----------RHRNRRRRADELAAAR MMAR_3652|M.marinum_M GGIPLLVVLSVLAVAVAIFWIVM-----------RYRASRRRTNALAAAR MAV_2041|M.avium_104 GRVILLATLAALLVAVMGLLLVM-----------RYRGRRRRAAALAAAR MAB_1706c|M.abscessus_ATCC_199 PWKPVLGALAFGAVLVGAFMLFS-----------WFRTRSRRRAEIEAAK TH_1853|M.thermoresistible__bu RVAEVEDAVRRHATLTESLAELEDG---------RRTADAQLAAAREAAE MUL_4399|M.ulcerans_Agy99 --AAVASLFAGYGQAYQSIS------------------------------ MLBr_01556|M.leprae_Br4923 GGRSDAGGGNYRGGGVGALPGGGSGGFRGRPGGGGHGGGGRPGQRGGAAG : Mflv_2720|M.gilvum_PYR-GCK RVD-PSDPEALAAVPLDALDDLSRKIVVDVDN---------------EVR Mvan_3816|M.vanbaalenii_PYR-1 RVD-PSDANALAAVPLDALDELSRKIVVDVDN---------------ELR MSMEG_4484|M.smegmatis_MC2_155 RVD-PTDPDALASVPLEALDALSREIVVDVDN---------------AVR Mb2374|M.bovis_AF2122/97 RVD-PTNVMALAAVPLQALDDLSRSMVVDVDN---------------AVR Rv2345|M.tuberculosis_H37Rv RVD-PTNVMALAAVPLQALDDLSRSMVVDVDN---------------AVR MMAR_3652|M.marinum_M RVD-PTDARALAAVPLDVLDELSRSMVVDVDN---------------AVR MAV_2041|M.avium_104 RLD-PTDLDALAALPLPTLDDLSRALVVDVDN---------------ALR MAB_1706c|M.abscessus_ATCC_199 GID-PSDAEALAKQPVTALDGLSKSIVVNVDN---------------AVR TH_1853|M.thermoresistible__bu AVERLTRQLAEAQLAAEAAEATHTASVAALNERRRLRAEIEERTAAVAAL MUL_4399|M.ulcerans_Agy99 ----------------LQANAFQAQFIQAING------------------ MLBr_01556|M.leprae_Br4923 AFGRPGGAPRRGRKSKRQKRQEYDSMQAPVVG----------------GV : Mflv_2720|M.gilvum_PYR-GCK TSESELALAVEEFGAQDTAAFTRAVEGAKTTLAQALN--------VRHIL Mvan_3816|M.vanbaalenii_PYR-1 TSESELALAVEEFGEQDTAPFSRAVANARTTLAQALN--------VRQIL MSMEG_4484|M.smegmatis_MC2_155 TSQAELELAVEEFGAKRTEPFTTAVANARKALAQAFN--------VRQIL Mb2374|M.bovis_AF2122/97 TSTNELALAIEEFGERRTAPFTQAVNNAKAALSQAFT--------VRQQL Rv2345|M.tuberculosis_H37Rv TSTNELALAIEEFGERRTAPFTQAVNNAKAALSQAFT--------VRQQL MMAR_3652|M.marinum_M TSSNELAVAIDEFGEQRTAPFSQAVSNAKAALSQAFS--------VRQQL MAV_2041|M.avium_104 TSANELDLAVAEFGDQRTQPFTQAVTNAKAALSQAFT--------VRQQL MAB_1706c|M.abscessus_ATCC_199 TSEAELALAVEEFGTESTAPFQQAVDSAKKALAQAFS--------VRKQL TH_1853|M.thermoresistible__bu QPEVDAALEAEATAREVQQEADTAAERAREAADAARERVDTARQAVQRLA MUL_4399|M.ulcerans_Agy99 --AGGAYVAAEAASTSPLQAFEDTVLGVINAPTQTLLG--------RPLI MLBr_01556|M.leprae_Br4923 RLPHGNGETIRLARGASLSDFAEKIDANPAALVQALFNLG-EMVTATQSV : : Mflv_2720|M.gilvum_PYR-GCK DDAVPETPMQRRDLLTRVIVAAAKADQELEAQREAFAALR---------D Mvan_3816|M.vanbaalenii_PYR-1 DDAVPETPMQRRDLLTRVIVAAAKADRELEAQREAFAQLR---------D MSMEG_4484|M.smegmatis_MC2_155 DDDVPETPLQQRDLLTRVIVSAARADRELEAQSAAFEQLR---------D Mb2374|M.bovis_AF2122/97 DDNTPETPAQRRELLTRVIVSAAHADRELASQTEAFEKLR---------D Rv2345|M.tuberculosis_H37Rv DDNTPETPAQRRELLTRVIVSAAHADRELASQTEAFEKLR---------D MMAR_3652|M.marinum_M DDSTPETPAQRRDLLTRVIVSAANADRELESQTEAFEKLR---------D MAV_2041|M.avium_104 DDGMPETPAQRRELLTQVIVSAARADRELESQTEAFEGLR---------D MAB_1706c|M.abscessus_ATCC_199 DDAIPETPLEQRRLLIDVITTAARADRTLEDQSSAFDALR---------N TH_1853|M.thermoresistible__bu DRAERDTLADRLRRIDAAATELARVDGELATLTVTEAALRQ----IEAAE MUL_4399|M.ulcerans_Agy99 GDGAAGTVANPNGGAGGFLYGNGGNGFSQTTAG----------------- MLBr_01556|M.leprae_Br4923 GDETLELLGSEMNYNVQVVSPEDEDRELLEPFDLTYGEDQGDEDELQVRP . . Mflv_2720|M.gilvum_PYR-GCK LVINAPSRLDTLTQQMIDLTTRITPAEQTLQQLKSQFAASALVS------ Mvan_3816|M.vanbaalenii_PYR-1 LLINAPSRLDTLTQQMVDLTARLTPAEQTLEQLKSQFAETALVS------ MSMEG_4484|M.smegmatis_MC2_155 LVINAPARLDLMTQQMVDLSARIETSQQTLAALHTQFDARALES------ Mb2374|M.bovis_AF2122/97 LVINAPARLDLLTQQYVELTTRIGPTQQRLAELHTEFDAAAMTS------ Rv2345|M.tuberculosis_H37Rv LVINAPARLDLLTQQYVELTTRIGPTQQRLAELHTEFDAAAMTS------ MMAR_3652|M.marinum_M LVINAPARLDLLTQRYIELTTRIAPTEQRLVELHDEFGATALSS------ MAV_2041|M.avium_104 LVINAPSRLDGLTQQYVELTARIGPAEQQLAALHNEFSAAALTS------ MAB_1706c|M.abscessus_ATCC_199 LVINAPAKLDTLTQQVVAVTARLPESERILGQLRTEFDAAALAS------ TH_1853|M.thermoresistible__bu LAVERAAGQAELASAHIELTAAVDLELRVGDEQLTIPAGGSWTAGATAPT MUL_4399|M.ulcerans_Agy99 VAGGAGGAAGLIGNGGMGGAGGAGAAGGAGGTGGWWFGNGGVGG------ MLBr_01556|M.leprae_Br4923 PVVTVMGHVDHGKTRLLDTIRKANVREAEAGGITQHIGAYQVGVDLDGSE . : Mflv_2720|M.gilvum_PYR-GCK --------------------VSDNIDEARSRLAYADQSITTARTLVSRPA Mvan_3816|M.vanbaalenii_PYR-1 --------------------VSDNIDEARQRLAFADQSITTARGLVSRPA MSMEG_4484|M.smegmatis_MC2_155 --------------------VAGNVDTARERLAFADRNITTARGLVSRPA Mb2374|M.bovis_AF2122/97 --------------------IAGNVTTATERLAFADRNISAARDLADQAV Rv2345|M.tuberculosis_H37Rv --------------------IAGNVTTATERLAFADRNISAARDLADQAV MMAR_3652|M.marinum_M --------------------ISANVASAHELLAFADSNISSARELSAKAV MAV_2041|M.avium_104 --------------------VSGNVTAAKERLAFADRNIGTARELAGQAV MAB_1706c|M.abscessus_ATCC_199 --------------------IGDNVAEATERVRFADSRITHGRELAARAL TH_1853|M.thermoresistible__bu EIELPGLLTARIVPGAPAAQMQETLDVARAALADALQHAGVADVASARSQ MUL_4399|M.ulcerans_Agy99 --------------------AGGAGTAGAVGFNGVSGGAGGAGGAAGWWG MLBr_01556|M.leprae_Br4923 R------------------LITFIDTPGHEAFTAMRARGAKATDIAILVV . . . Mflv_2720|M.gilvum_PYR-GCK H-RQGGLVDAIH---------SAEAALGQARTLLDAVDSASTDIN--RAV Mvan_3816|M.vanbaalenii_PYR-1 D-RQGGLVDAIH---------AAEAALGQARTLLDAVDSASTDIN--RAV MSMEG_4484|M.smegmatis_MC2_155 A-DQTGLVDAVR---------AAESALSQARTLLDAVDSASTDIN--RAL Mb2374|M.bovis_AF2122/97 SGRQAGLVDAVR---------AAESALGQARALLDAVDSAATDIR--HAV Rv2345|M.tuberculosis_H37Rv SGRQAGLVDAVR---------AAESALGQARALLDAVDSAATDIR--HAV MMAR_3652|M.marinum_M SGQQTGLVDAVR---------AAESALGQARSLLDAVDSAAGDIR--HAV MAV_2041|M.avium_104 SGQQGRLVDAVR---------AAESALGQARSLLDAVDHAAGDIR--HAI MAB_1706c|M.abscessus_ATCC_199 EGQQMSLVDAIR---------GAESALTQANALLDAIDNAANNIR--HAI TH_1853|M.thermoresistible__bu VERRRELSTARETFAATVVALTGEDTLERLRARLAELDAAASDDTGELGV MUL_4399|M.ulcerans_Agy99 AGGAGGQGGTGG----------MAGGYDNVNGVFGITAGNGGDGG----- MLBr_01556|M.leprae_Br4923 AADDGVMPQTVEAIN---HAQAADVPIVVAVNKIDKEGADPAKIRGQLTE : : . Mflv_2720|M.gilvum_PYR-GCK TGLPAVIADIQNGINSAGAQLAQG---SVAVATELSDARDAAVQAVAEAQ Mvan_3816|M.vanbaalenii_PYR-1 TGLPAVIADIQNGINQAGAQLAQG---NVAVATELSTARDAAVQAVSQAQ MSMEG_4484|M.smegmatis_MC2_155 AGLPAAVADIEAGIEQANDLLAQP---DTPQADKLATARDAAVQAAGEAK Mb2374|M.bovis_AF2122/97 ASLPAVVADIQTGIKRANQHLQQAQQPQTGRTGDLIAARDAAARALDRAR Rv2345|M.tuberculosis_H37Rv ASLPAVVADIQTGIKRANQHLQQAQQPQTGRTGDLIAARDAAARALDRAR MMAR_3652|M.marinum_M ATMPSVLADIQAGIQHANEQLQKSPANKSAYAAELIAARDAAARAVDNAR MAV_2041|M.avium_104 DQLPSAMADIENDIKRAAELLAATRDTKSGHAAELAAARDAATRAVEGAR MAB_1706c|M.abscessus_ATCC_199 DSLAASIADTKSDIAQAEEFQKQG---RLPSSEELTKAHDAAVAAVADAE TH_1853|M.thermoresistible__bu DDAQAELTAAERAYQQAHTDCETHRKAAVLAARRLAEKSQTAAALREKLT MUL_4399|M.ulcerans_Agy99 -------AGGRGGWLFGDAG-------AGGQGGLGGDGNYAGQGSYGGVG MLBr_01556|M.leprae_Br4923 YGLVAEDFGGDTMFIDISAKVGTN-IEALLEAVLLTADAALDLRANSGME Mflv_2720|M.gilvum_PYR-GCK SS-GETDPLGAFTRLTQADADLDRLLAEVAEERETAARLSR---TFDQAL Mvan_3816|M.vanbaalenii_PYR-1 ST-GNSDPLGAFTRLTQADADLDRLLAEVAEERETAERLSR---TFDQAL MSMEG_4484|M.smegmatis_MC2_155 SN-GTADPLGTFTRLTQADADLDQLLATVHEQREAAERLAR---TLEQAI Mb2374|M.bovis_AF2122/97 ---GAADPLTAFDQLTKVDADLDRLLATLAEEQATADRLNR---SLEQAL Rv2345|M.tuberculosis_H37Rv ---GAADPLTAFDQLTKVDADLDRLLATLAEEQATADRLNR---SLEQAL MMAR_3652|M.marinum_M VT-GAADPLSAFAQLTTADADLDRLLAAIAQEQANAEHLRR---SLEQAL MAV_2041|M.avium_104 AG-APDDPLGAFGQLTKADAGLNAVLAAVAQERAAAERLAR---SLEQAL MAB_1706c|M.abscessus_ATCC_199 RI-GATDPLTAFTHLAAADAQLDKLLAAAQEERAAAERRAR---VLDQAL TH_1853|M.thermoresistible__bu AARTELDTAAARLAAQRADVDDETLVVRAAAHGEEAERAAVRVAQLNAEL MUL_4399|M.ulcerans_Agy99 GAGGAGGAAGMFGSGGSGGAGGEGGAFGDGNAGGSGS------------- MLBr_01556|M.leprae_Br4923 AQGVAIEAHLDRGRGPVATVLVQRGTLRIGDSVVAGDAYGRVRRMVDEHG . . : . Mflv_2720|M.gilvum_PYR-GCK FNAQSRVRAVSDYIDTRRGAIGPEARTRLAEAVRQLQAARDKQDTNLNEA Mvan_3816|M.vanbaalenii_PYR-1 FNAQSRVRAVSDYIDTRRGAIGPEARTRLAEAVRQLQAARDKRETNLNEA MSMEG_4484|M.smegmatis_MC2_155 FTAESRITAVSDYIETRRGSIGPEARTRLAEATRQLEAARAKRSTNPNEA Mb2374|M.bovis_AF2122/97 FTAESRVRAVSEYIDTRRGSIGPEARTRLAEAKRQLEAAHDRKSSNPTEA Rv2345|M.tuberculosis_H37Rv FTAESRVRAVSEYIDTRRGSIGPEARTRLAEAKRQLEAAHDRKSSNPTEA MMAR_3652|M.marinum_M FTAESRIRAVSDYIDTRRGSIGPEARTRLAEAGRRLDAAQSYRSTNPTEA MAV_2041|M.avium_104 FTAQSRVRAVSDYIDTRRGSIGPEARTRLAEAQRHLHAAADRRATDPADA MAB_1706c|M.abscessus_ATCC_199 VAARQRLDAVNQYIGLHRGAVGARTRWNLDEAQRRLAAAEQSRASNPSDA TH_1853|M.thermoresistible__bu SAAQPDQVAAALDTAARHAETVHAEHRRTADALRELNAQLEVYGSEGRKG MUL_4399|M.ulcerans_Agy99 -GGHGGNGGNGGWLYGDAGAGGQGGNAAPGAYSDNLGTFQSSYTSGNGGA MLBr_01556|M.leprae_Br4923 VDIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKRNA . . . . : . Mflv_2720|M.gilvum_PYR-GCK IAHANGAAMLAAQAQSLANSDVTAAQRHFNGPYGGGGGGG------QMGA Mvan_3816|M.vanbaalenii_PYR-1 IAHANGAAMLAAQAQSLANSDVTAAQRHFSGPYGGGGGG-------QMGA MSMEG_4484|M.smegmatis_MC2_155 VAHANGASTLAAQAQSLANDDVRAAQRSYTSHHGGGGAD--------MGA Mb2374|M.bovis_AF2122/97 IAYANAASTLAAHAQSLANADVQSAQRAYT---RRGGNN--------AGA Rv2345|M.tuberculosis_H37Rv IAYANAASTLAAHAQSLANADVQSAQRAYT---RRGGNN--------AGA MMAR_3652|M.marinum_M IAQANAASTLAANAQSLANSDVQAAQRAYT---RQGGNN--------TGA MAV_2041|M.avium_104 IAHANAASTLAAEAQSLANGDVQAARRAYP---RGGGGD--------MGA MAB_1706c|M.abscessus_ATCC_199 ILFANGAAELATQAQYSAQQEVQSAQRYYG---NGYGGYS------VAGD TH_1853|M.thermoresistible__bu ELDAAKAEREQAEAEFLRIGRLARAVKLLRETMLRHRDASRRRYVDPFRA MUL_4399|M.ulcerans_Agy99 GGNGGVAGMIGTGGAGGAGGAGGVNAFDSGGGGGGGGNGG-------NGG MLBr_01556|M.leprae_Br4923 LAARSRKRISLEDLDSALKETSQLNLILKGDNAGTVEALEEALMGIQVDD Mflv_2720|M.gilvum_PYR-GCK VIG----GILIGNVLSGVLRGGLGG----------------GGFGGGFG- Mvan_3816|M.vanbaalenii_PYR-1 VIG----GILIGNVLSGALRGGFGG----------------GGFGGGFG- MSMEG_4484|M.smegmatis_MC2_155 VLG----GIIIGNVLRGGFGGGGGY----------------GGYGGGFGG Mb2374|M.bovis_AF2122/97 ILG----GIIIGDLLSGGTRGGLG-----------------GWIPTSFGG Rv2345|M.tuberculosis_H37Rv ILG----GIIIGDLLSGGTRGGLG-----------------GWIPTSFGG MMAR_3652|M.marinum_M VLG----GIIIGDLLSGGMRGGFG-----------------GWSPTSFGG MAV_2041|M.avium_104 MLG----GIIIGDLLSSGMRGGFG-----------------GWSPASFGG MAB_1706c|M.abscessus_ATCC_199 VAGN-VAGAVIGGILRGMLSGGAGH----------------HSSWSGSGS TH_1853|M.thermoresistible__bu EVER-LGRIVFGDSFEVEIDSDLCIRSRTLAGRTVDYESLSGGAKEQLGI MUL_4399|M.ulcerans_Agy99 AGG------ASGALIEAGGVGGSGG----------------GGGAGVVGP MLBr_01556|M.leprae_Br4923 EVALRVIDRGVGGITETNVNLASASDAIIIG--------FNVRAEGKATE * Mflv_2720|M.gilvum_PYR-GCK -GGGFGGG----------------------------GGGGFSGGGGRF-- Mvan_3816|M.vanbaalenii_PYR-1 -GGGFGGG----------------------------GGG-FSGGGGRF-- MSMEG_4484|M.smegmatis_MC2_155 FGGGFGGGRSS-------------GRPTSYGGSSHSSGRNYGGGGGRF-- Mb2374|M.bovis_AF2122/97 SSNAPGSS----------------------------PDGGFLGGGGRF-- Rv2345|M.tuberculosis_H37Rv SSNAPGSS----------------------------PDGGFLGGGGRF-- MMAR_3652|M.marinum_M SSGSSGDS----------------------------SGGGFLGGGGRF-- MAV_2041|M.avium_104 STSSSG--------------------------------GGVLGGGGRF-- MAB_1706c|M.abscessus_ATCC_199 SSYGGSSR---------------------------SSGSSFRGGGGRF-- TH_1853|M.thermoresistible__bu VARLAGAALVARDDTVPVVIDDALGFTDAERLVKMGAVFDAVGGDGQVIV MUL_4399|M.ulcerans_Agy99 PAGNPGND----------------------------GLDGVTGASGLLFG MLBr_01556|M.leprae_Br4923 LASREGVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQLGRAEIRALFRS . . . Mflv_2720|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3816|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_4484|M.smegmatis_MC2_155 -------------------------------------------------- Mb2374|M.bovis_AF2122/97 -------------------------------------------------- Rv2345|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_3652|M.marinum_M -------------------------------------------------- MAV_2041|M.avium_104 -------------------------------------------------- MAB_1706c|M.abscessus_ATCC_199 -------------------------------------------------- TH_1853|M.thermoresistible__bu LTCSPDRYAGISDAHRIELTA----------------------------- MUL_4399|M.ulcerans_Agy99 G------------------------------------------------- MLBr_01556|M.leprae_Br4923 SKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTSLRREKDDVTEV Mflv_2720|M.gilvum_PYR-GCK -------------------------------- Mvan_3816|M.vanbaalenii_PYR-1 -------------------------------- MSMEG_4484|M.smegmatis_MC2_155 -------------------------------- Mb2374|M.bovis_AF2122/97 -------------------------------- Rv2345|M.tuberculosis_H37Rv -------------------------------- MMAR_3652|M.marinum_M -------------------------------- MAV_2041|M.avium_104 -------------------------------- MAB_1706c|M.abscessus_ATCC_199 -------------------------------- TH_1853|M.thermoresistible__bu -------------------------------- MUL_4399|M.ulcerans_Agy99 -------------------------------- MLBr_01556|M.leprae_Br4923 REGFECGMTLGYSDIKEGDVIESYELVEKQRA