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M. avium 104 MAV_1428 (-)

annotation: hypothetical protein MAV_1428
coordinates: 1396533 - 1399163
length: 876

VKLHRLTLTNYRGIAHREIEFPDHGVVVVCGANEIGKSSMIEALDLLLEAKDRSTKKEVKQVKPTHSDVG
AEVSAEISCGPYRFVYRKRFHKKCETELTVITPYREQLTGDEAHERVRAMLAETVDSDLWHAQRVLQAAS
TAAVDLSGCDALSRALDVAAGDSGGLCGTEPLLIERIDAEYARYFTPTGRPTGEWAAAIARLADAEAAVA
ECAAAVAEVDERVSRHAALTEQVADLSQRRIAAGPRVTAARQAADRIAELTAQRREAQLVAEAAAATKAA
AAQAHSGRLQLLADIDTRAAAVTQTHAQVQQAAADHAVAQADAQACDTALQHATEALAELERRVQEAQRT
VERSAGREEADRLAARLDKIDAIQRDRERISAELSTIAVTEELLRRIEDAAAAVDRIGDQLASTSAAVEF
TAVADIHLVIGDRQVSLPAGQSWSITAVGPTAVEVPGVLTARVTPGATTLDVQAKHAAAQQELAAALTAG
AVADLGAARSADQRRRELQGTRDQLGATLAGLCGDEPLDELRSRLARLRAEHPEQPAAPTGGAADLAAAR
TELEALAQARACASAECVTRRQAATAAAARLAETATAATVLQNRLDTLRAELDAATGRLAAERASVGDEE
LAASADAALRAEQAAERRVAELADALAAASPDSVAAELADATQESESLRERYEEAAGALREVTIELSVFG
SEGRQGKLDAAETEREHAASEHSQVGRRARAAQLLRSVMTRHRDTTRQRYVEPYRAELQRLGRPVFGPTF
EVDIDSDLCIRSRTLNGITVPYESLSGGAKEQLGILARLAGAALVAKEDAVPVVVDDALGFTDPDRLAKM
GQLFDSVGSHGQVIVLTCSPDRYDGVKGAHRIDLSA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_1428--100% (876)hypothetical protein MAV_1428
M. avium 104MAV_3777smc2e-1424.96% (701) chromosome segregation protein SMC
M. avium 104MAV_2041-8e-0925.05% (479) hypothetical protein MAV_2041

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1309-0.071.92% (876) hypothetical protein Mb1309
M. gilvum PYR-GCKMflv_2256-0.054.75% (884) hypothetical protein Mflv_2256
M. tuberculosis H37RvRv1278-0.071.92% (876) hypothetical protein Rv1278
M. leprae Br4923MLBr_01120-0.068.80% (875) hypothetical protein MLBr_01120
M. abscessus ATCC 19977MAB_1421-0.051.83% (876) hypothetical protein MAB_1421
M. marinum MMMAR_4142-0.068.91% (878) hydrolase
M. smegmatis MC2 155MSMEG_5002-0.057.47% (877) hypothetical protein MSMEG_5002
M. thermoresistible (build 8)TH_1853-0.056.51% (876) conserved hypothetical protein
M. ulcerans Agy99MUL_4005-0.068.56% (878) hydrolase
M. vanbaalenii PYR-1Mvan_4435-0.054.52% (884) hypothetical protein Mvan_4435

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2256|M.gilvum_PYR-GCK          MKLHRLVLTNYRGITHRDIEFPDRGVVVVSGANEVGKSSMLEALDLLLES
Mvan_4435|M.vanbaalenii_PYR-1       MKLHRLALTNYRGITHRDIEFPDRGVVVVSGPNEAGKSSMLEALDLLLES
MSMEG_5002|M.smegmatis_MC2_155      MKLHRLVLTNYRGITHREIEFPDHGVVVVSGANEIGKSSMIEALDLLIEA
TH_1853|M.thermoresistible__bu      MRLHRLALTNYRGIARREVEFPDRGVVVVSGANEIGKSSMIEALDLLFHA
MMAR_4142|M.marinum_M               MKLHRLVLTNYRGIAHREIEFPDHGVVVVCGANEIGKSSMIEALDLLLEF
MUL_4005|M.ulcerans_Agy99           MKLHRLVLTNYRGIAHREIEFPDHGVVVVCGANEIGKSSMIEALDLLLEF
MLBr_01120|M.leprae_Br4923          MKLHRLALTNYRGTARREIEFPDRGVILVCGANEIGKSSMIEALDLLLEF
Mb1309|M.bovis_AF2122/97            MKLHRLALTNYRGIAHRDVEFPDHGVVVVCGANEIGKSSMVEALDLLLEY
Rv1278|M.tuberculosis_H37Rv         MKLHRLALTNYRGIAHRDVEFPDHGVVVVCGANEIGKSSMVEALDLLLEY
MAV_1428|M.avium_104                MKLHRLTLTNYRGIAHREIEFPDHGVVVVCGANEIGKSSMIEALDLLLEA
MAB_1421|M.abscessus_ATCC_1997      MKLHRLSVTNYRGITHRDITFPERGVVVVGGANEVGKTSMIEALDLLIES
                                    *:**** :***** ::*:: **::**::* *.** **:**:******:. 

Mflv_2256|M.gilvum_PYR-GCK          KDRSNKKEIKQVKPTHADVGAEVTAEISAGPYRFVYRKRFHKKPETELTV
Mvan_4435|M.vanbaalenii_PYR-1       KDRSSKKEVKQVKPTHADVGAEVTAEISAGPYRFVYRKRFHKRPETELTV
MSMEG_5002|M.smegmatis_MC2_155      KDRSSKKEVKQVKPTHADVGAEVSAEISTGPYRFLYRKRFHKRAETQLTI
TH_1853|M.thermoresistible__bu      KDRSTKKEVKQVKPTHADVGAEITAEISTGPYRFVYHKRFHKKCATQLTI
MMAR_4142|M.marinum_M               KDRSAKKEIKQVKPTNADVGSEVTAEISSGPYRFVYRKRFHKKCETQLTV
MUL_4005|M.ulcerans_Agy99           KDRSAKKEIKQVKPTNADVGSEVTAEISSGPYRFVYRKRFHKKCETQLTV
MLBr_01120|M.leprae_Br4923          RDRSTKKEVKQVKPANADIGSEVCAEISSGTYRFVYRKRFNKKCETALTV
Mb1309|M.bovis_AF2122/97            KDRSTKKEVKQVKPTNADVGSEVIAEISSGPYRFVYRKRFHKRCETELTV
Rv1278|M.tuberculosis_H37Rv         KDRSTKKEVKQVKPTNADVGSEVIAEISSGPYRFVYRKRFHKRCETELTV
MAV_1428|M.avium_104                KDRSTKKEVKQVKPTHSDVGAEVSAEISCGPYRFVYRKRFHKKCETELTV
MAB_1421|M.abscessus_ATCC_1997      KDRSTKKDVKQVKPTFADVGSEVEAEISCGPYRFVYRKRFHKRAETHLTV
                                    :*** **::*****: :*:*:*: **** *.***:*:***:*:  * **:

Mflv_2256|M.gilvum_PYR-GCK          VAPRRQQFTGDEAHERVRAMLAETVDLDLWQAQRVLQSAPTTAADLSACD
Mvan_4435|M.vanbaalenii_PYR-1       LTPRREQLTGDEAHERVRAILAESVDLDLWQAQRVLQSAPTSAADLSGCN
MSMEG_5002|M.smegmatis_MC2_155      LSPVREQLSGDEAHQRVLAMLAETVDTDLWQAQRVLQASSTAPVDLSGSD
TH_1853|M.thermoresistible__bu      LAPRREELSGDEAHERALAMLSETVDMELWRTQRVLQAGSTAPVDLSGCD
MMAR_4142|M.marinum_M               LAPRREQLTGDEAHERVRAILAETVDTELWRAQRVLQAASTTAVDLSSCD
MUL_4005|M.ulcerans_Agy99           LAPRREQLTGDEAHERVRAILAETVDTKLWRAQRVLQAASTTAVDLSSCD
MLBr_01120|M.leprae_Br4923          LAPHREQLTGDEAHERVRAMLAETVDNDLWHAQRVLQAASTAAVDLSGCD
Mb1309|M.bovis_AF2122/97            LAPRREQLTGDEAHERVRTMLAETVDTELWHAQRVLQAASTAAVDLSGCD
Rv1278|M.tuberculosis_H37Rv         LAPRREQLTGDEAHERVRTMLAETVDTELWHAQRVLQAASTAAVDLSGCD
MAV_1428|M.avium_104                ITPYREQLTGDEAHERVRAMLAETVDSDLWHAQRVLQAASTAAVDLSGCD
MAB_1421|M.abscessus_ATCC_1997      IEPRREQLSGDEAHQRVLDMLDQSIDMNLWKAQRVLQSAGAGVLDLSSSD
                                    : * *::::*****:*.  :* :::* .**::*****:. :   ***..:

Mflv_2256|M.gilvum_PYR-GCK          ALSRALDVVAGEVD-DDPAPG-GAVDTLLVDRIDEEYRRYFTLTGKPTGE
Mvan_4435|M.vanbaalenii_PYR-1       ALSRALDVVAGEVD-DVSATGAGNVESLLVDRVEEEYRRYFTSTGRATGE
MSMEG_5002|M.smegmatis_MC2_155      ALARALDVAAGEA---VSLSG---DEPLLIERIEGEYQRYFTATGRPTGE
TH_1853|M.thermoresistible__bu      ALSRALDAVAGEA---VQTSG---TEPLLIDRIDAEYRKYFTATGRPTGE
MMAR_4142|M.marinum_M               ALSRALDIAAAHSATDVALSG---AEPVLIERIDTEYSRYFTPTGRPTGE
MUL_4005|M.ulcerans_Agy99           ALSRALDIAAAHSATDVALSG---AEPVLIERIDAEYSRYFTPTGRPTGE
MLBr_01120|M.leprae_Br4923          ALSRALDLAAGDHA---ELSG---TEPLLIERIEAEYRRYFTSTGRPTGE
Mb1309|M.bovis_AF2122/97            ALSRALDLAAGDDA---ALSG---TESLLIERIEAEYARYFTPTGRPTGE
Rv1278|M.tuberculosis_H37Rv         ALSRALDLAAGDDA---ALSG---TESLLIERIEAEYARYFTPTGRPTGE
MAV_1428|M.avium_104                ALSRALDVAAGDSG---GLCG---TEPLLIERIDAEYARYFTPTGRPTGE
MAB_1421|M.abscessus_ATCC_1997      ALTRALDLAAGQS---VALSG---SEPDLVERIDAEYALYFTGTGRPTGE
                                    **:**** .*..        *    :. *::*:: **  *** **:.***

Mflv_2256|M.gilvum_PYR-GCK          WAAATKRLRDADEQVARCAAAVAEVDEAVRRHAALTADLAVLSAERVTAA
Mvan_4435|M.vanbaalenii_PYR-1       WAAATARLRAADEEVARCAAAMAEVDEAVRRHAALTTDMAQLAVETASAA
MSMEG_5002|M.smegmatis_MC2_155      WAAAVKRLQAADAEVARCAAAVAEVDDAVHRHQELSAEVSRLAGECEQAT
TH_1853|M.thermoresistible__bu      WLAATKRLQAADEQVARCAARVAEVEDAVRRHATLTESLAELEDGRRTAD
MMAR_4142|M.marinum_M               WAATLARLSGAETAVAECAAAVSEVDERISRHGELTRQAAELAPQLAAAG
MUL_4005|M.ulcerans_Agy99           WAATLARLSGAETAVAECAAAVSEVDERISRHGELTRQAAELAPKLAAAG
MLBr_01120|M.leprae_Br4923          WAVAISRLSDAETAVGECAAAVAEVDDRVRRHAVLTERVAGLAQQRFAAG
Mb1309|M.bovis_AF2122/97            WSAAVSRLAAAEAAVADCAAAVAEVDDGVRRHTELTEQVAELSQQLLAHQ
Rv1278|M.tuberculosis_H37Rv         WSAAVSRLAAAEAAVADCAAAVAEVDDGVRRHTELTEQVAELSQQLLAHQ
MAV_1428|M.avium_104                WAAAIARLADAEAAVAECAAAVAEVDERVSRHAALTEQVADLSQRRIAAG
MAB_1421|M.abscessus_ATCC_1997      WARAGARLTAAEDALASARAAMAEVDQQVREHDELTQELASVIADRAEVN
                                    *  :  **  *:  :. . * ::**:: : .*  *:   : :        

Mflv_2256|M.gilvum_PYR-GCK          AHLESAAQAEKKVAALRADLDRATARAEAATSTHTASQSALTERRRCRAD
Mvan_4435|M.vanbaalenii_PYR-1       ERLQSARNAAAAVAVLQGELDQATARAEAARSVHAASKAALAQRRRARAD
MSMEG_5002|M.smegmatis_MC2_155      QRLTATRTAADAVDALRQQLKEAQVVAEAAHVTHAASVAALTERRRMRAE
TH_1853|M.thermoresistible__bu      AQLAAAREAAEAVERLTRQLAEAQLAAEAAEATHTASVAALNERRRLRAE
MMAR_4142|M.marinum_M               SRLAAARQAADKVAGLKAEAHEAKLVTAAKAATSSASAAAHAERRALCEE
MUL_4005|M.ulcerans_Agy99           SRLAAARQAADKVAGLKAEAHEAKLVTAAKAATSSASAAAHAERRALCEE
MLBr_01120|M.leprae_Br4923          PRLAVAQAAADKVAVLTRQAREAELVAAAATATNAAAVAAHTSRLRLLAE
Mb1309|M.bovis_AF2122/97            LRLEAARVAAEKIAAITDDAREAKLIATAAAATSGASTAAHAGRLGLLTE
Rv1278|M.tuberculosis_H37Rv         LRLEAARVAAEKIAAITDDAREAKLIATAAAATSGASTAAHAGRLGLLTE
MAV_1428|M.avium_104                PRVTAARQAADRIAELTAQRREAQLVAEAAAATKAAAAQAHSGRLQLLAD
MAB_1421|M.abscessus_ATCC_1997      RRLAPLEEASQAVTTLVQQHDNAVVVAEAAQAAAVAAQTKRDERAQLVAD
                                     ::     *   :  :  :  .*   : *   .  *:      *     :

Mflv_2256|M.gilvum_PYR-GCK          IDDRTATITRLQAESAVATDELDTAAQMKVAADEAAEKARLALTAGQERV
Mvan_4435|M.vanbaalenii_PYR-1       LDERSATVTSLQTESDTAADELDTANEMQVAAEEAAGKARSALAACQERV
MSMEG_5002|M.smegmatis_MC2_155      IDERAATITELQAALVTAAEEAETAREVVTAAEEEAERAKAAVADHEARV
TH_1853|M.thermoresistible__bu      IEERTAAVAALQPEVDAALEAEATAREVQQEADTAAERAREAADAARERV
MMAR_4142|M.marinum_M               IDSRAKALEALQIDAQHAADQRAMASADAQRCDVAVEEATASLTAVQRRA
MUL_4005|M.ulcerans_Agy99           IDSRAKALEALQIDAQHAADQRAMASADAQRCDVAVEEATASLTAVQRRA
MLBr_01120|M.leprae_Br4923          IDTRAVVLAATQDEAQEAVDAVSTMRADAEASDAAVEESTEALMAAQQRA
Mb1309|M.bovis_AF2122/97            IDTRTAAVVAAEAKARQAADEQATARAEAEACDAALTEATQVLTAVRLRA
Rv1278|M.tuberculosis_H37Rv         IDTRTAAVVAAEAKARQAADEQATARAEAEACDAALTEATQVLTAVRLRA
MAV_1428|M.avium_104                IDTRAAAVTQTHAQVQQAAADHAVAQADAQACDTALQHATEALAELERRV
MAB_1421|M.abscessus_ATCC_1997      IRARRVSIDMLAEQLSATAEAHGTAQQVCEAAEAAAAQATESVDAARVQL
                                    :  *   :         :             .:    .:       . : 

Mflv_2256|M.gilvum_PYR-GCK          DAARGAVQRLADREEVDRLAGRIATIERHQRELDAVSGELAAIALTDPLM
Mvan_4435|M.vanbaalenii_PYR-1       DAARVAVQRLADREEADRLTGRIATIERHGRELEAVQRDLTAITLTDALL
MSMEG_5002|M.smegmatis_MC2_155      DAARAAVERLSDRDEADRLDMRLAKIDAATRELQAVTDELKTITLDDTAM
TH_1853|M.thermoresistible__bu      DTARQAVQRLADRAERDTLADRLRRIDAAATELARVDGELATLTVTEAAL
MMAR_4142|M.marinum_M               EAARRSLDQIADREQAQRLSARLARIGEVQCDHDRVCAQLSEVTLTEALL
MUL_4005|M.ulcerans_Agy99           EAARRSLDQIADREQAQRLSARLARIGEVQCDHDRVCAQLSEVTLTEALL
MLBr_01120|M.leprae_Br4923          DIARSTVDQLVDRQEADRLSTRLAKIDAIQGERDLICAELSAVTLTEQLL
Mb1309|M.bovis_AF2122/97            ESARRTLDQLADCEEADRLAARLARIDDIEGDRDRVCAELSAVTLTEELL
Rv1278|M.tuberculosis_H37Rv         ESARRTLDQLADCEEADRLAARLARIDDIEGDRDRVCAELSAVTLTEELL
MAV_1428|M.avium_104                QEAQRTVERSAGREEADRLAARLDKIDAIQRDRERISAELSTIAVTEELL
MAB_1421|M.abscessus_ATCC_1997      EAARGTLDRALARDEVDGLAARVSRIDLTNRQLASVGAELSSLVITAQSL
                                    : *: ::::     : : *  *:  *     :   :  :*  :.:    :

Mflv_2256|M.gilvum_PYR-GCK          TAIEKAAAVVDRATAAVAYASARMELVAAADLEISVDGSTVTLNAGDTWS
Mvan_4435|M.vanbaalenii_PYR-1       ADIETAAAAVERATAAVEQTSAHIEVTAAADVEVRIGDADMTLRAGDTWA
MSMEG_5002|M.smegmatis_MC2_155      RAIEKAALAVERAAGQAELASARIELVAQNGLDVRVDDATVALQAGAEWS
TH_1853|M.thermoresistible__bu      RQIEAAELAVERAAGQAELASAHIELTAAVDLELRVGDEQLTIPAGGSWT
MMAR_4142|M.marinum_M               KRIESAAASVDRVDGQLALISAAVEFTAAADIELVVGGQRVQLSAGSSWS
MUL_4005|M.ulcerans_Agy99           KRIESAAASVDRVDGQLALISAAVEFTAAADIELVVDGQRVQLSAGLSWS
MLBr_01120|M.leprae_Br4923          QRIENAAAIVDRTGEQLKLISAAVEFTATADIEISVGQQRVSLEAGQSWS
Mb1309|M.bovis_AF2122/97            SRIERAAAAVDRGGAQLASISAAVEFTAAVDIELGVGDQRVSLSAGQSWS
Rv1278|M.tuberculosis_H37Rv         SRIERAAAAVDRGGAQLASISAAVEFTAAVDIELGVGDQRVSLSAGQSWS
MAV_1428|M.avium_104                RRIEDAAAAVDRIGDQLASTSAAVEFTAVADIHLVIGDRQVSLPAGQSWS
MAB_1421|M.abscessus_ATCC_1997      GAIETAARAVGMAEAALETASAQVELRALVDVDIAVNGEQLRVAAGDRWS
                                      ** *   *          ** :*. *  .:.: :.   : : **  *:

Mflv_2256|M.gilvum_PYR-GCK          AGVSADTGVDVAGVLSLRITPGASASATQSELDDATAALSDALAQAGVAD
Mvan_4435|M.vanbaalenii_PYR-1       AAVGTATGIDLPGVLSVQVIPGASAAATAAALDTAAARLADALRAAGVDD
MSMEG_5002|M.smegmatis_MC2_155      VSTTTRTEIDVPGVLSVRVVPGTPAAETQARLDDAQAVLTAALQAVGAES
TH_1853|M.thermoresistible__bu      AGATAPTEIELPGLLTARIVPGAPAAQMQETLDVARAALADALQHAGVAD
MMAR_4142|M.marinum_M               MTATGPAEVEVPGVLTARITQGATALEAQAKYVAAQEELAVALAAGGVAT
MUL_4005|M.ulcerans_Agy99           MTATGPAEVEVPGVLTARIIQGATALEAQAKYVAAQEELAVALAAGGVAT
MLBr_01120|M.leprae_Br4923          TTATGPTEVEVLGVLTACVIPGATALDAQSKYVAAQEELSVALADGGVVD
Mb1309|M.bovis_AF2122/97            VTATGPTEVKVPGVLTARIVPGATALDFQAKYAAAQQELADALAAGEVAD
Rv1278|M.tuberculosis_H37Rv         VTATGPTEVKVPGVLTARIVPGATALDFQAKYAAAQQELADALAAGEVAD
MAV_1428|M.avium_104                ITAVGPTAVEVPGVLTARVTPGATTLDVQAKHAAAQQELAAALTAGAVAD
MAB_1421|M.abscessus_ATCC_1997      SAATDTIEITAPGVAVARIIPGPNAAQLRDKLDTARQTLSGALADAGVAD
                                      .     :   *:    :  *. :         *   *: **    .  

Mflv_2256|M.gilvum_PYR-GCK          LAAARALDAHRQQLCGARRQVSAILDALTAEDSVADLQTRLTAVQARIP-
Mvan_4435|M.vanbaalenii_PYR-1       VEAARALDRRRHELSAAGRQIRAILEALAADDSVDQLRARLADLQARTP-
MSMEG_5002|M.smegmatis_MC2_155      VDVARALDARRRELLGSRDRLRATLDALVGDDDIARLRDRLAALRAGQT-
TH_1853|M.thermoresistible__bu      VASARSQVERRRELSTARETFAATVVALTGEDTLERLRARLAELDAAAS-
MMAR_4142|M.marinum_M               LAEARSVEQRRRELLGRRDQLSATLAGLCGDEQVDQLRCRLAQLQASQP-
MUL_4005|M.ulcerans_Agy99           LAEARSVEQRRRELLGRRDQLNATLAGLCGDEQVDQLRCRLAQLQASQP-
MLBr_01120|M.leprae_Br4923          LAAARCANQRRRELQSSLDQLSAALAGVCGDDQIDQLRARLEQLRDGYP-
Mb1309|M.bovis_AF2122/97            LAAARSADLCRRELLSRRDQLTATLAGLCGDEQVDQLRSRLEQLCAGQP-
Rv1278|M.tuberculosis_H37Rv         LAAARSADLCRRELLSRRDQLTATLAGLCGDEQVDQLRSRLEQLCAGQP-
MAV_1428|M.avium_104                LGAARSADQRRRELQGTRDQLGATLAGLCGDEPLDELRSRLARLRAEHPE
MAB_1421|M.abscessus_ATCC_1997      VGEAQKQFERRTELNAERDRLTALLDGLMGPESLEALREKLSRLRELVP-
                                    :  *:     * :*      . * : .: . : :  *: :*  :    . 

Mflv_2256|M.gilvum_PYR-GCK          --AADGLFDTDA-AILDPAAQRLELIEATAAHQDAIRDCETHRKVADQAG
Mvan_4435|M.vanbaalenii_PYR-1       --AEEGLFDTDTRGSLDPAAQRLELVEATAAHQQAIRDCETHRKVAEEAA
MSMEG_5002|M.smegmatis_MC2_155      --DDGGLFDVEGPADID--TARAQLAADVAAHREAVAHCETARKAVAVAA
TH_1853|M.thermoresistible__bu      --DDTGELGVDD--------AQAELTAAERAYQQAHTDCETHRKAAVLAA
MMAR_4142|M.marinum_M               --AEPDLFATDA------TAARAELEAAEAARITAGKQCEDQRKLALAAS
MUL_4005|M.ulcerans_Agy99           --AEPDLFATDA------TAARAELEAAEAARITAGKQCEDQRKLAVAAS
MLBr_01120|M.leprae_Br4923          --GEPDLLAVDI------GSARAELEAAETVRAAVDFEREVCRRTAAAAN
Mb1309|M.bovis_AF2122/97            --AELDLVSTDT------ATARAELDAVEAARIAAEKDCETRRQIAAGAA
Rv1278|M.tuberculosis_H37Rv         --AELDLVSTDT------ATARAELDAVEAARIAAEKDCETRRQIAAGAA
MAV_1428|M.avium_104                QPAAPTGGAADL------AAARTELEALAQARACASAECVTRRQAATAAA
MAB_1421|M.abscessus_ATCC_1997      --EATGLWDAIDP-----AQARAEVARLVGEVERLQAEEVTHRRAVQTAG
                                             .           : ::            .    *: .  * 

Mflv_2256|M.gilvum_PYR-GCK          KLVAQRELNAARIAQKLQSAQHELTTIAARLAEQRASVGDEELALKTDAD
Mvan_4435|M.vanbaalenii_PYR-1       KLSAKRGLHAARLLEKLQAAQAELAAAGARLAEQRAATSDDELAVKAEAD
MSMEG_5002|M.smegmatis_MC2_155      ARDTEKSTRLSVLREKLTAAQTELTTCSARLEAQRAGTPDEALALKVQAD
TH_1853|M.thermoresistible__bu      RRLAEKSQTAAALREKLTAARTELDTAAARLAAQRADVDDETLVVRAAAH
MMAR_4142|M.marinum_M               RRLAETSTSATVLQSRLENGRAEVEAATSRLATARAAVSDADLASAADAD
MUL_4005|M.ulcerans_Agy99           RRLAETSTSATVLQSRLENGRAEVEAATSRLATARAAVSDADLASAADAD
MLBr_01120|M.leprae_Br4923          CRLVETSARANFLLKKAETQRAELDQDIDQLAQQRASVSDEDLASAAEAG
Mb1309|M.bovis_AF2122/97            RRLAETSTRATVLQNAAAAESAELGAAMTRLACERASVGDDELAAKAEAD
Rv1278|M.tuberculosis_H37Rv         RRLAETSTRATVLQNAAAAESAELGAAMTRLACERASVGDDELAAKAEAD
MAV_1428|M.avium_104                ARLAETATAATVLQNRLDTLRAELDAATGRLAAERASVGDEELAASADAA
MAB_1421|M.abscessus_ATCC_1997      QQLAEKAAEAMAAREKHAARAEELAAAEQRLAHVRSSASDDLLTERHERA
                                       .:         .       *:     :*   *: . *  *.      

Mflv_2256|M.gilvum_PYR-GCK          AETAAKAVAAVAELRDELARHHPDAVVAALAEAERALATVTARRDEAVEA
Mvan_4435|M.vanbaalenii_PYR-1       AEAAAAAEAAVARVGAELAGHEPEAVAAALVDAERAAAEVGARHHEVGEA
MSMEG_5002|M.smegmatis_MC2_155      DEQAKATAARVATLRDELDRSAPDSVLAELADAQRHAQSVQTRHDAATEG
TH_1853|M.thermoresistible__bu      GEEAERAAVRVAQLNAELSAAQPDQVAAALDTAARHAETVHAEHRRTADA
MMAR_4142|M.marinum_M               LHVLQASQRRLAELAEVLDAAEPEAVAAELREAAEIAQSLDERHDAVVAA
MUL_4005|M.ulcerans_Agy99           LHVLQASQRRLAELTEVLDAAEPEAVAAEAREAAEIAQSLGERHDAVVAA
MLBr_01120|M.leprae_Br4923          LRAVQIAEQRVAKLTEELVAAEPEAVTAELVAATAAAESLRDQHEDAAGA
Mb1309|M.bovis_AF2122/97            LRVLQTAEQRVIDLADELAATAPDAVAAELAEAADAVELLRERHDEAIRA
Rv1278|M.tuberculosis_H37Rv         LRVLQTAEQRVIDLADELAATAPDAVAAELAEAADAVELLRERHDEAIRA
MAV_1428|M.avium_104                LRAEQAAERRVAELADALAAASPDSVAAELADATQESESLRERYEEAAGA
MAB_1421|M.abscessus_ATCC_1997      VQAADLTSRRVTDLVSQLAALEADRVRAELAEVSARAQALDRRHEATRDR
                                     .    :   :  :   *    .: * *    .      :  .   .   

Mflv_2256|M.gilvum_PYR-GCK          LREIAAQLKVFGTEGRKGNLDAAETERERAEAEFGRVQRRARAAQLLRTV
Mvan_4435|M.vanbaalenii_PYR-1       LREIAAQLKVYGTEGRKGGLDAAETERGRAEAEFVRVQRRARAAELLRSV
MSMEG_5002|M.smegmatis_MC2_155      LREVSAQLKVYGTEGRKGQLDEAETEREHANAEYLRVHRRARAAELLRSV
TH_1853|M.thermoresistible__bu      LRELNAQLEVYGSEGRKGELDAAKAEREQAEAEFLRIGRLARAVKLLRET
MMAR_4142|M.marinum_M               LRDISVELSVFGSEGRQSKLDAAETEREHAASQHARIGRRARAAQLLRSV
MUL_4005|M.ulcerans_Agy99           LRDISVELSVFGSEGRQSKLDAAETEREHAASQHARIGRRARAAQLLRSV
MLBr_01120|M.leprae_Br4923          LREISIELSVFGTEGRQGKLDTAEAEREHAISQHTQIGRRARAAQLLRSV
Mb1309|M.bovis_AF2122/97            LHEVGVELSVFGTQGRKGKLDAAETEREHAASHHARVGRRARAARLLRSV
Rv1278|M.tuberculosis_H37Rv         LHEVGVELSVFGTQGRKGKLDAAETEREHAASHHARVGRRARAARLLRSV
MAV_1428|M.avium_104                LREVTIELSVFGSEGRQGKLDAAETEREHAASEHSQVGRRARAAQLLRSV
MAB_1421|M.abscessus_ATCC_1997      LRDISVRLEVFGRQGRQDQLDAAASEREYAATEFARIGAKARAVDTLRSV
                                    *:::  .*.*:* :**:. ** * :**  * :.. ::   ***.  ** .

Mflv_2256|M.gilvum_PYR-GCK          MGRHRDAMRQRYVDPFRTEVERLGRIVFGDTFEVDVDSELRIGHRTLSGR
Mvan_4435|M.vanbaalenii_PYR-1       MGRHRDAMRQRYVDPFRGEVERLGRIVFGDSFEVDVDSSLCIGNRTLSGR
MSMEG_5002|M.smegmatis_MC2_155      MTRHRDATRQRYVDPFRNEVQRLGRLVFGEDFEVDVDSKLRISTRTVSGR
TH_1853|M.thermoresistible__bu      MLRHRDASRRRYVDPFRAEVERLGRIVFGDSFEVEIDSDLCIRSRTLAGR
MMAR_4142|M.marinum_M               MTRHRDTTRQRYVEPYRMELQRLGRPVFGPTFEVDVGSDLRIRSRTLDDV
MUL_4005|M.ulcerans_Agy99           MTRHRDTTRQRYVEPYRMELQRLGRPVFGPTFEVDVGSDLRIRSRTLDDV
MLBr_01120|M.leprae_Br4923          MARHRDTTRLRYVEPYRTELQRLGRPVFGPTFEVDIDSDLRIRSRTLDGI
Mb1309|M.bovis_AF2122/97            MARHRDTTRLRYVEPYRAELHRLGRPVFGPSFEVEVDTDLRIRSRTLDDR
Rv1278|M.tuberculosis_H37Rv         MARHRDTTRLRYVEPYRAELHRLGRPVFGPSFEVEVDTDLRIRSRTLDDR
MAV_1428|M.avium_104                MTRHRDTTRQRYVEPYRAELQRLGRPVFGPTFEVDIDSDLCIRSRTLNGI
MAB_1421|M.abscessus_ATCC_1997      MMRHRDGMRLRYVDPFRAELERLGRMVFGPTFEVDIDSDLSIRSRTLEGR
                                    * ****  * ***:*:* *:.**** ***  ***::.:.* *  **: . 

Mflv_2256|M.gilvum_PYR-GCK          TVPYESLSGGAKEQLGIVARLAGATLVASEDSVPVVIDDALGFTDADRLT
Mvan_4435|M.vanbaalenii_PYR-1       TVPYESLSGGAKEQLGIVARLAGAALVAKEDSVPVVIDDALGFTDTERLT
MSMEG_5002|M.smegmatis_MC2_155      TVPYESLSGGAKEQLAIVARLAGASLVAKEDTVPVIIDDALGFTDADRLT
TH_1853|M.thermoresistible__bu      TVDYESLSGGAKEQLGIVARLAGAALVARDDTVPVVIDDALGFTDAERLV
MMAR_4142|M.marinum_M               TVPYESLSGGAKEQLGILARFAGAALVAKEDTVPVVVDDALGFTDPDRLA
MUL_4005|M.ulcerans_Agy99           TVPYESLSGGAKEQLGILARFAGAALVAKEDTVPVVVDDALGFTDPDRLA
MLBr_01120|M.leprae_Br4923          TVPFESLSGGAKEQLGILARFAGATLVAKEDNVPVVVDDALGFTDPDRLA
Mb1309|M.bovis_AF2122/97            TVPYECLSGGAKEQLGILARLAGAALVAKEDAVPVLIDDALGFTDPERLA
Rv1278|M.tuberculosis_H37Rv         TVPYECLSGGAKEQLGILARLAGAALVAKEDAVPVLIDDALGFTDPERLA
MAV_1428|M.avium_104                TVPYESLSGGAKEQLGILARLAGAALVAKEDAVPVVVDDALGFTDPDRLA
MAB_1421|M.abscessus_ATCC_1997      TVPYESLSGGAKEQLGIVARLASAALVAPQDAVPVIIDDALGFTDSDRLE
                                    ** :*.*********.*:**:*.*:*** :* ***::********.:** 

Mflv_2256|M.gilvum_PYR-GCK          KMAEVFDAVAGDGQVIILTCSPQRYADVRSARHIELVAG-
Mvan_4435|M.vanbaalenii_PYR-1       KMAEVFDAVAGDGQVIILTCSPQRYAGVRTAQHIELIAG-
MSMEG_5002|M.smegmatis_MC2_155      KMGAVFDAVGGDGQVIVLTCSPDRYASVHGAHHIALTA--
TH_1853|M.thermoresistible__bu      KMGAVFDAVGGDGQVIVLTCSPDRYAGISDAHRIELTA--
MMAR_4142|M.marinum_M               KMGGVFDTVGTHGQVIVLTCSPDRYDGVAGAHRIDLNL--
MUL_4005|M.ulcerans_Agy99           KMGGVFDTVGTHGQVIVLTCSPDRYDGVAGAHRIDLNL--
MLBr_01120|M.leprae_Br4923          KMGEMFDTVGAHGQVIVLTCSPDRYDGFTGAHRIDLNV--
Mb1309|M.bovis_AF2122/97            KMGEVFDTIGADGQVIVLTCSPTRYGGVKGAHRIDLDAIQ
Rv1278|M.tuberculosis_H37Rv         KMGEVFDTIGADGQVIVLTCSPTRYGGVKGAHRIDLDAIQ
MAV_1428|M.avium_104                KMGQLFDSVGSHGQVIVLTCSPDRYDGVKGAHRIDLSA--
MAB_1421|M.abscessus_ATCC_1997      RMGEVFGAVGTETQVIVLTCSPDRYRAVTGAQRISLSA--
                                    :*. :*.::. . ***:***** **  .  *::* *