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MIWTNSGDSHFLEPDDLWQSRLPKRLADLTPRAEKDPDGEYETVFVDGQIFRRKLPSSAMEAFFEESMKP KGIRDAKARIGDLDKEGVWGEVIFPSLGMWASTFRTPELLKACMRASNEWALEEICAVSPRYVVTAQVST LVVDDAIEELRWAAEQGFKAVFLPTTPHPSAPDWHRKEWEPFWAAAEDAGMVIAFHIGTDPVDMTVGGAS GGAGMVYRGPGGAVLNYAETTFSGQRAAMKMVASGALDRHPDLKVLISEGGATWVPFLGDRMLEGYRQHH MAVRPKLSRSPKEILFSQVYASFQHDETAVAAFDHMGYKNVMFGSDYPHMEGTFGHTQDTLKGLFDGVSD ETRLRITQGTFYELFPDVPPIPAEKL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1917 | - | - | 100% (376) | amidohydrolase 2 |
| M. avium 104 | MAV_2629 | - | 0.0 | 93.99% (316) | amidohydrolase 2 |
| M. avium 104 | MAV_0475 | - | 1e-39 | 29.92% (361) | amidohydrolase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2441 | - | 1e-26 | 26.32% (342) | amidohydrolase 2 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_00947 | - | 3e-08 | 44.68% (47) | hypothetical protein MLBr_00947 |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2618 | - | 1e-35 | 30.49% (387) | amidohydrolase |
| M. smegmatis MC2 155 | MSMEG_4837 | - | 2e-28 | 27.78% (378) | amidohydrolase 2 |
| M. thermoresistible (build 8) | TH_2827 | - | 5e-24 | 27.07% (362) | PUTATIVE amidohydrolase 2 |
| M. ulcerans Agy99 | MUL_3143 | - | 9e-34 | 29.97% (387) | amidohydrolase |
| M. vanbaalenii PYR-1 | Mvan_4211 | - | 2e-27 | 27.19% (342) | amidohydrolase 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2441|M.gilvum_PYR-GCK -------------------------------MDKNDMILISVDDHIVEPP
Mvan_4211|M.vanbaalenii_PYR-1 ---------------MSRAPARKGGNGRSAVMNRDDMILISVDDHIVEPP
MSMEG_4837|M.smegmatis_MC2_155 -------------------------------MNKDDMILISVDDHIIEPP
MMAR_2618|M.marinum_M MKSIDELASDLSFTTAKTGADRSVTFLPDPPRARRRYTVISVDDHIVEPP
MUL_3143|M.ulcerans_Agy99 --------------------------MTDPPRARRRYTVISVDDHIVEPP
MAV_1917|M.avium_104 -----------------------------------MIWTNSGDSHFLEPD
MLBr_00947|M.leprae_Br4923 ---------------------------------------MAAQEQFL---
TH_2827|M.thermoresistible__bu -------------------------------VTAPALEIWDADNHLYEPT
:.::
Mflv_2441|M.gilvum_PYR-GCK DMFKNHLSKKYLDEAPRLVHNEDGSDTWQ-FRDVVIPNVALNAVAGRPKE
Mvan_4211|M.vanbaalenii_PYR-1 DMFKNHLPRKYLDEAPRLVHNPDGSDTWQ-FRDVVIPNVALNAVAGRPKE
MSMEG_4837|M.smegmatis_MC2_155 DMFKNHLPAKYRDEAPRLVHNPDGSDTWQ-FRDTVIPNVALNAVAGRPKE
MMAR_2618|M.marinum_M DTFTGRLPQRFADRAPRVVETDDGGQVWV-YDGQVLPNVGFNAVVGRPVS
MUL_3143|M.ulcerans_Agy99 DTFTGRLPQRFADRAPRVVETDDGGQVWV-YDGQVLPNVGFNAVVGRPVS
MAV_1917|M.avium_104 DLWQSRLPKRLADLTPRAEKDPDGEYETV-FVDGQIFRRKLPSSAMEAFF
MLBr_00947|M.leprae_Br4923 ---------------PATTAAPD---------------------------
TH_2827|M.thermoresistible__bu DAYTRHLPKQYRGAIQWIQVDGLTKLMIKGRLTDTIPNPTYEVVASPGAW
Mflv_2441|M.gilvum_PYR-GCK EYGLEPQGLD-----------EIRPGCWQVDERVKDMNAGGILGSMCFPS
Mvan_4211|M.vanbaalenii_PYR-1 EYGLEPQGLD-----------EIRPGCWQVDERVKDMNAGGILGSMCFPS
MSMEG_4837|M.smegmatis_MC2_155 EYGLEPQGLD-----------EIRKGCYDPNERVKDMNAGGVLATMNFPS
MMAR_2618|M.marinum_M EYGFEPVRFD-----------EMRRGAWDIHERIKDMDLNGVYASLNFPS
MUL_3143|M.ulcerans_Agy99 EYGFEPVRFD-----------EMRRGAWDIHERIKDMDLNGVYASLNFPS
MAV_1917|M.avium_104 EESMKP------------------KGIRDAKARIGDLDKEGVWGEVIFPS
MLBr_00947|M.leprae_Br4923 --------------------------VRDLEKRIADLDSEGIWSESVFPS
TH_2827|M.thermoresistible__bu ADYFRGINPEGKSLRELANPIRCPEEFRHAEQRLRLLDAQGIQACVMFPT
. . *: :: *: . **:
Mflv_2441|M.gilvum_PYR-GCK F-PGFAGR--LFATEDPEFSLALVQAYNDWHVEEWCGAYPARFIPMTLPV
Mvan_4211|M.vanbaalenii_PYR-1 F-PGFAGR--LFATEDAEFSLALVQAYNDWHVEEWCGAYPARFIPMTLPV
MSMEG_4837|M.smegmatis_MC2_155 F-PGFAAR--LFATDDEEFSLALVQAYNDWHIDEWCASNPGRFIPMAIPA
MMAR_2618|M.marinum_M FLPGFAGQRLQQVTKDPELAWAAVRAWNDWHLEAWAGPYPERIIPCQLPW
MUL_3143|M.ulcerans_Agy99 FLPGFAGQRLQQVTKDPELAWAAVRAWNDWHLEAWAGPYPERIIPCQLPW
MAV_1917|M.avium_104 L--GMWAS----TFRTPELLKACMRASNEWALEEICAVSP-RYVVTAQVS
MLBr_00947|M.leprae_Br4923 L--GTWSG---------SFLDSGAVALSDAGIQRLVQKNNYQLIIAAN--
TH_2827|M.thermoresistible__bu TGGMLEER----MLDDIELTHAVVHAYNEWLLEEWTFDYAGRIFATPVIT
.: : * .: :: : .
Mflv_2441|M.gilvum_PYR-GCK IWDPEACAKEIRRNAARGVHSLTFSENPSAMGYPSFHDF--DHWKPMWDA
Mvan_4211|M.vanbaalenii_PYR-1 IWDPEACAKEIRRNAARGVHSLTFSENPSAMGYPSFHDF--EHWKPMWDA
MSMEG_4837|M.smegmatis_MC2_155 IWNPGLAAAEVRRVAEKGVHSLTFTENPSTLGYPSFHDL--EYWRPLWQA
MMAR_2618|M.marinum_M LLDPSAGAQLIHENAERGFRAVSFSENPAMLGLPSIHS---GHWDPMMAA
MUL_3143|M.ulcerans_Agy99 LLDPSAGAQLIHENAERGFRAVSFSENPAMLGLPSIHS---GHWDPMMAA
MAV_1917|M.avium_104 TLVVDDAIEELRWAAEQGFKAVFLPTTPHPS-APDWHR---KEWEPFWAA
MLBr_00947|M.leprae_Br4923 -----SHNTSVKY-------------------------------------
TH_2827|M.thermoresistible__bu LPDVDKAVAELNWCVENGARAVLVNPRPVATITGHTTSMGQPYFDPFWHR
:.
Mflv_2441|M.gilvum_PYR-GCK LVDTDTVLNVHIGSS------------GRLAITAPDAPMDVMITLQPMNI
Mvan_4211|M.vanbaalenii_PYR-1 LVDTDTVLNVHIGSS------------GRLAITAPDAPMDVMITLQPMNI
MSMEG_4837|M.smegmatis_MC2_155 LVDTETVMNVHIGSS------------GKLAITAPDAPMDVMITLQPMNI
MMAR_2618|M.marinum_M CAETGTVVNLHIGSS------------GSSPSTTDDAPADVPGVLFFAYA
MUL_3143|M.ulcerans_Agy99 CAETGTVVNLHIGSS------------GSSPSTTDDAPADVPGVLFFAYA
MAV_1917|M.avium_104 AEDAGMVIAFHIGTDPVDMTVGGASG-GAGMVYRGPGGAVLNYAETTFSG
MLBr_00947|M.leprae_Br4923 --------------------------------------------------
TH_2827|M.thermoresistible__bu VEQLGIPVLMHACDSGYDRYSRDWEGKGGEYTPFKPDAFRTIVYEDARSI
Mflv_2441|M.gilvum_PYR-GCK VQAAADLLWSRPIKEYPDLKIALSEGGTGWIPYFLERVDRTY---EMHST
Mvan_4211|M.vanbaalenii_PYR-1 VQAAADLLWSRPIKEYPDLKIALSEGGTGWIPYFLERVDRTY---EMHST
MSMEG_4837|M.smegmatis_MC2_155 VQAAADLLWSAPIKEFPTLKIALSEGGTGWIPYFLDRVDRTF---EMHST
MMAR_2618|M.marinum_M ISAAVDWLYSGLPSRFPDLKICLSEGGIGWVAGLLDRLDHMLSYHEMYGT
MUL_3143|M.ulcerans_Agy99 ISAAVDWLYSGLPSRFPDLKICLSEGRIGWVAGLLDRLDHMLSYHEMYGT
MAV_1917|M.avium_104 QRAAMKMVASGALDRHPDLKVLISEGGATWVPFLGDRMLEGYR----QHH
MLBr_00947|M.leprae_Br4923 --------------------------------------------------
TH_2827|M.thermoresistible__bu LDTCAALVAHGVFTRHPGVRVGVVENGGAWVPRLIDLFERVYK-------
Mflv_2441|M.gilvum_PYR-GCK WTGQDFKGKLPSEVFREHFLTCFIADPVGVATRHQIGVDNICWEADYPHS
Mvan_4211|M.vanbaalenii_PYR-1 WTGQDFKGKLPSEVFREHFLTCFIADPVGVATRHQIGVDNICWEADYPHS
MSMEG_4837|M.smegmatis_MC2_155 WTHQNFGGKLPSEVFREHFMTCFISDPVGVKNRHMIGIDNICWEMDYPHS
MMAR_2618|M.marinum_M WRAMG-ESLTPAEVFTRNFWFCAVEDKSSFVQHHRIGTENIMVESDYPHC
MUL_3143|M.ulcerans_Agy99 WRAMG-ESLTSAEVFTRNFWFCAVEDKSSFVQHYRIGTENIMVESDYPHC
MAV_1917|M.avium_104 MAVRPKLSRSPKEILFSQVYASFQHDETAVAAFDHMGYKNVMFGSDYPHM
MLBr_00947|M.leprae_Br4923 --------------------------------------------------
TH_2827|M.thermoresistible__bu -KMPNEFGAHPVEQFREHVWVNPFHEEDLSGLIDLIGADRVLFGSDFPHP
Mflv_2441|M.gilvum_PYR-GCK DSMWPGAPEQLDEVLKANNVPDDEINKMTYENAMRWYHWDPFTHIAKEQA
Mvan_4211|M.vanbaalenii_PYR-1 DSMWPGAPEQLDEVLKVNSVPDDEIDKMTYQNAMRWYHWDPFTHIPKEQA
MSMEG_4837|M.smegmatis_MC2_155 DSMWPGAPEELSAVFDTYDVPDDEINKITHENAMRLYHFDPFAHVPKEQA
MMAR_2618|M.marinum_M DSTWPHTQQTMHEQLDG--LPADVIRKITWENAARLYQHPVPVAIAQNPE
MUL_3143|M.ulcerans_Agy99 DSTWPHTQQTMHEQLDG--LPADVIRKITWENAARLYQHPVPVAIAQNPE
MAV_1917|M.avium_104 EGTFGHTQDTLKGLFDG--VSDETRLRITQGTFYELFPDVPPIPAEKL--
MLBr_00947|M.leprae_Br4923 --------------------------------------------------
TH_2827|M.thermoresistible__bu EG----LAEPAKLTPEIAELPEPTIEAVMGGNLRELLTAVPHGR------
Mflv_2441|M.gilvum_PYR-GCK TVGALRKAAEGHDVSIQALSNKEKTGTTFSDFAASAKSISGNKD
Mvan_4211|M.vanbaalenii_PYR-1 TVGALRKAAEGHDVSIQALSHKEKTGATFADFAARAKEITGNTD
MSMEG_4837|M.smegmatis_MC2_155 TVGALRKAAEGHDVSIRALSKKDKTGASFADFQANAKAVSGARD
MMAR_2618|M.marinum_M AF------------------------------------------
MUL_3143|M.ulcerans_Agy99 AF------------------------------------------
MAV_1917|M.avium_104 --------------------------------------------
MLBr_00947|M.leprae_Br4923 --------------------------------------------
TH_2827|M.thermoresistible__bu --------------------------------------------