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MEAFIEESMKPQGIRDAKARLGDLDKEGVWGEVIFPSLGMWASTFRTPELLKACMRASNEWALEEICAVS PRYVVTAQVSTLIVEDAVEELHWAASEGFKAVFLPTTPHPSAPDWHRKEWEPFWAAAEEAGMVIAFHIGT DPVDMTIGGASGGAGMVYRGPGGAVMNYAETTFSGQRAAMKMVASGALDRHPDLRVLISEGGATWVPFLG DRMVEGYRQHHMAVRPKLNRSPKEILYSQVYASFQHDETAVAAYEHMGYKNVMFGSDYPHMEGTFGHTQD TLKGLFDGVSDETRLRITQGTFYVLFPDVPPIPAEKF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2629 | - | - | 100% (317) | amidohydrolase 2 |
| M. avium 104 | MAV_1917 | - | 0.0 | 93.99% (316) | amidohydrolase 2 |
| M. avium 104 | MAV_0475 | - | 7e-36 | 31.51% (292) | amidohydrolase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2371 | - | 7e-21 | 24.35% (271) | amidohydrolase 2 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_00947 | - | 8e-08 | 43.18% (44) | hypothetical protein MLBr_00947 |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4820 | - | 7e-30 | 33.11% (302) | hypothetical protein MMAR_4820 |
| M. smegmatis MC2 155 | MSMEG_2235 | - | 5e-21 | 27.60% (279) | amidohydrolase family protein |
| M. thermoresistible (build 8) | TH_0554 | - | 4e-22 | 29.01% (293) | amidohydrolase family protein |
| M. ulcerans Agy99 | MUL_0389 | - | 1e-29 | 32.78% (302) | hypothetical protein MUL_0389 |
| M. vanbaalenii PYR-1 | Mvan_4275 | - | 5e-21 | 25.09% (271) | amidohydrolase 2 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4820|M.marinum_M ----MDRYTVISADCHAGADLLDYREYLEAKYQ-----DEFDDWAKTFVN
MUL_0389|M.ulcerans_Agy99 ----MDRYTVISADCHAGADLFDYREYLEAKYQ-----DEFDDWAKTFVN
MSMEG_2235|M.smegmatis_MC2_155 MTEQFTDAPIFDADQHMYETAEALTKFLPERYRRAVQYAQIGRHTRVVIN
TH_0554|M.thermoresistible__bu MSPRSLPYPVFDIDNHMYETTDALIKFLPREHRGKVGYVELNGRKKLMVK
Mflv_2371|M.gilvum_PYR-GCK --MREDDLILVSIDDHVVEPPDMFLRHVPEKYKEEAPIVVTDEKG-----
Mvan_4275|M.vanbaalenii_PYR-1 --MQTDDLILVSIDDHVVEPPDMFLRHVPAKYREEAPIVVTDDKG-----
MAV_2629|M.avium_104 -----------------------MEAFIEESMK-----------------
MLBr_00947|M.leprae_Br4923 --------------------------------------------------
MMAR_4820|M.marinum_M ----------PFGDLSEPDAEHNWDSDRRNAELDSDGVAG---EVIFPNT
MUL_0389|M.ulcerans_Agy99 ----------PFGDLSEPDAEHNWDSDRRNAELDSDGVAG---EVIFPNT
MSMEG_2235|M.smegmatis_MC2_155 NRVTDFIPNPTFERVAAPGAHEKFFAGENTEGLTLREMQGKPIEAPAATR
TH_0554|M.thermoresistible__bu DRISHMIPNPTFEKVARPGSAEDYFLGNNPEGLNFREFVGEPMEVIPAFQ
Mflv_2371|M.gilvum_PYR-GCK --------VDQWMYQGRPQGVSGLNAVVSWPAEEWGRDPAGFAEMRPGVY
Mvan_4275|M.vanbaalenii_PYR-1 --------VDQWMYQGRPQGVSGLNAVVSWPAEEWGRDPAGFAEMRPGVY
MAV_2629|M.avium_104 -----------------PQGIR--DAKARLGDLDKEGVWG----------
MLBr_00947|M.leprae_Br4923 --------------------------------------------------
MMAR_4820|M.marinum_M VPP--------------FFPQGSLAAPP-PSTARDLELRWAGLRAHNRWL
MUL_0389|M.ulcerans_Agy99 VPP--------------FFPQGSLAAPA-PSTARDLELRWAGLRAHNRWL
MSMEG_2235|M.smegmatis_MC2_155 NPEDRIAELDRQGVVEALIYPTLGSLVE-HSSADDPQLTLAIIHALNEWI
TH_0554|M.thermoresistible__bu HPAPRLELMDELGIDRCVMYPTLASLIE-ERTTDDVVLTHAVMHALNQWM
Mflv_2371|M.gilvum_PYR-GCK DVHERVRDMNRNGILASMCFPTFTGFSARHLNMTREDVTLVMVSAYNDWH
Mvan_4275|M.vanbaalenii_PYR-1 DVHERVRDMNRNGILASMCFPTFTGFSARHLNMHREEATLVMVSAYNDWH
MAV_2629|M.avium_104 ----------------EVIFPSLGMWAS---TFRTPELLKACMRASNEWA
MLBr_00947|M.leprae_Br4923 ------------------------------------------MAAQEQFL
: * : :
MMAR_4820|M.marinum_M ADFCSLSPE-RRAGVGQILLGDVDEAVAEVAQIAKLGLRGGVLLPGVAPG
MUL_0389|M.ulcerans_Agy99 ADFCSLSPE-RRAGVGQILLGDVDEAVAEVAQIAKLGLPGGVLLPGVAPG
MSMEG_2235|M.smegmatis_MC2_155 LEHWTFNHADRLFTTPIINLSEVEAAQRELAWILEHGAKAALIKPGPVNG
TH_0554|M.thermoresistible__bu HEHWSFDYEGRIFATPVITLPIVEEAIRELHWCLERGMRTFLVRPAPVPS
Mflv_2371|M.gilvum_PYR-GCK IDEWAGSYPDRFIPIAILPTWTPEGMCNEIRRVAAKGCRAVTMP--ELPH
Mvan_4275|M.vanbaalenii_PYR-1 IDEWAGSYPDRFIPIAILPTWNVEAMCAEIRRVAAKGCRAVTMP--ELPH
MAV_2629|M.avium_104 LEEICAVSP-RYVVTAQVSTLIVEDAVEELHWAASEGFKAVFLPTTPHPS
MLBr_00947|M.leprae_Br4923 P--------------ATTAAPDVRDLEKRIADLDSEG-------------
.: *
MMAR_4820|M.marinum_M --TGIPALYAEHWEPLWAACAQAGLVINHHGGNAGPSP-IDGWG------
MUL_0389|M.ulcerans_Agy99 --TGIPALYAEHWEPLWAACAQAGLVINHHGGNAGPSP-IDGWG------
MSMEG_2235|M.smegmatis_MC2_155 -LHGWRSPALPEFDPFWRDVEAAGLPIVLHASFPPLDDYINKWEPAH-TQ
TH_0554|M.thermoresistible__bu RFGGSRSMGLPEFDPFWQEVVNAGIPVTMHASDSGYQKHLMEWEGGD-EY
Mflv_2371|M.gilvum_PYR-GCK LEGLPSYHDEDYWGPVFRTLSEENVVMCLHIG-TGFGAISMAPN------
Mvan_4275|M.vanbaalenii_PYR-1 LEGLPSYHDDDYWGPVFRTLSEENVVMCLHIG-TGFGAISMAPN------
MAV_2629|M.avium_104 ----APDWHRKEWEPFWAAAEEAGMVIAFHIGTDPVDMTIGGASGGAGMV
MLBr_00947|M.leprae_Br4923 ---------------IWSES------------------------------
.:
MMAR_4820|M.marinum_M ----SSLAVWVYESHWWAHRALWHLIFSGVLDRYPDLTVVLTEQGTGWIP
MUL_0389|M.ulcerans_Agy99 ----SSLAVLVYESHWWAHRALLHLIFSGVLDRYPDLTVVLTEQGTGWIP
MSMEG_2235|M.smegmatis_MC2_155 NFMTQSAFRWMVLGHREIADMLTALICHGTLTRFPRLRIASVENGSSWIF
TH_0554|M.thermoresistible__bu LSFKPSALREVVMGHRAIEDTLAAMICHGALSRFPDLKILCVENGSGWVR
Mflv_2371|M.gilvum_PYR-GCK ----APIDNLIILATQVSAMCAQDLLWGPAMRNYPDLKFAFSEGGIGWIP
Mvan_4275|M.vanbaalenii_PYR-1 ----APIDNLIILATQVSAMCAQDLLWGPAMRNYPDLKFAFSEGGIGWIP
MAV_2629|M.avium_104 YRGPGGAVMNYAETTFSGQRAAMKMVASGALDRHPDLRVLISEGGATWVP
MLBr_00947|M.leprae_Br4923 --------------------------------VFPSL-------G-TWSG
.* * * *
MMAR_4820|M.marinum_M ATLDSLDVAAARYRRPNSAIARFAGPTAGSLPLQPSQYWARQCYVGASFL
MUL_0389|M.ulcerans_Agy99 ATLDSLDVAAARYRRPNSAIARFAGPTAGSLPLQPSQYWARQCYVGASFL
MSMEG_2235|M.smegmatis_MC2_155 PLFRDFADLYKKMPQ--------------NFPEHPHDVFRRNIWVSP-FW
TH_0554|M.thermoresistible__bu NLLEQLDTAYRIMPK--------------EFDEHPVEVFKRNIYIHP-FL
Mflv_2371|M.gilvum_PYR-GCK FYLDRSDRHYTNQKWLRR-----------DFGDKLPSDVFREHSLACYVT
Mvan_4275|M.vanbaalenii_PYR-1 FYLDRSDRHYTNQKWLRR-----------DFGDKLPSDVFREHSLACYVT
MAV_2629|M.avium_104 FLGDRMVEGYRQHHMAVR----------PKLNRSPKEILYSQVYASF-QH
MLBr_00947|M.leprae_Br4923 SFLDS---------------------------------------------
MMAR_4820|M.marinum_M RPVECAQRHRIGVDRIMWGSDYPHMEGTAPYSREALRHTFSDVDPDE--V
MUL_0389|M.ulcerans_Agy99 RPVECAQRHRIGVDRIMWASDYPHMEGTAPYSREALRHTFSDVDPDE--V
MSMEG_2235|M.smegmatis_MC2_155 EGCVADVVETVGWDKVLFGSDYPHPEGLA--EPKGFWKYAEGMDIRR--T
TH_0554|M.thermoresistible__bu EDDVPGLIEIMGADHVLFGSDYPHPEGIG--DPLSFVDRLEGVSEAD--K
Mflv_2371|M.gilvum_PYR-GCK DKTSLKLRHEIGIDIIAWECDYPHSDCFWPDAPEQVLAELNAAGASDSDI
Mvan_4275|M.vanbaalenii_PYR-1 DKTSLKLRHEIGIDIIAWECDYPHSDCFWPDAPEKVLAELNAAGASDSDI
MAV_2629|M.avium_104 DETAVAAYEHMGYKNVMFGSDYPHMEGTFGHTQDTLKGLFDGVSDET--R
MLBr_00947|M.leprae_Br4923 ---GAVALSDAGIQRLVQKNNY---------------QLIIAANSHN---
* . : :* .
MMAR_4820|M.marinum_M AAMVGGNAAAVYGFDLQALAP-LAARIGPTVTEVAEPLAAIPADASSTAF
MUL_0389|M.ulcerans_Agy99 AAMVGGNAAAVYGFDLQALAP-LAARIGPTVTEVAEPLAAIPADASSTAF
MSMEG_2235|M.smegmatis_MC2_155 YDFMGDNARRFMGLPIANPDP-DAVKPPALTASS----------------
TH_0554|M.thermoresistible__bu AKIMGGNAMGLLGIRVPA--------------------------------
Mflv_2371|M.gilvum_PYR-GCK NKITWQNSCRFFGWDPFKLTPRDQATAGALRAKAADVDTSIRPRAEWARL
Mvan_4275|M.vanbaalenii_PYR-1 NKITWENSCRFFSWDPFKLTPKEQATAGALRAKATDVDTSIRPRAEWARL
MAV_2629|M.avium_104 LRITQGTFYVLFPDVPPIPAEKF---------------------------
MLBr_00947|M.leprae_Br4923 ------TSVKY---------------------------------------
.
MMAR_4820|M.marinum_M EPDPIRAW--
MUL_0389|M.ulcerans_Agy99 EPDPIRAW--
MSMEG_2235|M.smegmatis_MC2_155 ----------
TH_0554|M.thermoresistible__bu ----------
Mflv_2371|M.gilvum_PYR-GCK YHEK-QLTKA
Mvan_4275|M.vanbaalenii_PYR-1 YNEKQQFAQA
MAV_2629|M.avium_104 ----------
MLBr_00947|M.leprae_Br4923 ----------