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VKAWNDFYIDEWCATAPDRYIPLAILPVWDIDATVAEAERVAAKGARTVSFPDSPVPMGLPSFHSDHWDG LWRVCSETQMPVSLHFGSGSFVPGFSFSSMKPIAGQMVVPDAPFAVATTLFSSNLMWTTVDLLFSGKLQQ FPDLQFSLAEGGIGWVPYILERSDYVWERHRYYQDIDFDTRPSDLFRKHFWGCFIDDMHGLKNRHEIGID RITLEIDFPHSDSNWPNSRKRAAEVLADVPDDECSLIVEENARRMLNFPRLTAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1874 | - | - | 100% (264) | amidohydrolase 2 |
| M. avium 104 | MAV_2591 | - | e-146 | 89.73% (263) | amidohydrolase 2 |
| M. avium 104 | MAV_1837 | - | 1e-82 | 55.98% (259) | amidohydrolase 2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4324 | - | 2e-56 | 39.47% (266) | amidohydrolase 2 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4742 | - | 6e-59 | 41.00% (261) | metal-dependent amidohydrolase |
| M. smegmatis MC2 155 | MSMEG_4837 | - | 1e-58 | 41.60% (262) | amidohydrolase 2 |
| M. thermoresistible (build 8) | TH_2339 | - | 1e-49 | 40.23% (261) | amidohydrolase 2 |
| M. ulcerans Agy99 | MUL_3143 | - | 3e-43 | 34.35% (262) | amidohydrolase |
| M. vanbaalenii PYR-1 | Mvan_2022 | - | 2e-55 | 39.10% (266) | amidohydrolase 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4324|M.gilvum_PYR-GCK -----MNRDDMILISVDDHIVEPPDMFKNHLSKKYLVEAPRLVHNEDGSD
Mvan_2022|M.vanbaalenii_PYR-1 -----MNRDDMILISVDDHIVEPPDMFKNHLPSKYLDEAPRLVHNPDGSD
MMAR_4742|M.marinum_M -----MNKEDMILISVDDHTVEPPNMFKNHLSAKYLDDAPRLVHNPDGSD
MSMEG_4837|M.smegmatis_MC2_155 -----MNKDDMILISVDDHIIEPPDMFKNHLPAKYRDEAPRLVHNPDGSD
TH_2339|M.thermoresistible__bu -MSHDLRPEDLILVSIDDHVVEPPDMFLRHVPAKYRDEAPIVVTDENGVD
MUL_3143|M.ulcerans_Agy99 MTDPPRARRRYTVISVDDHIVEPPDTFTGRLPQRFADRAPRVVETDDGGQ
MAV_1874|M.avium_104 --------------------------------------------------
Mflv_4324|M.gilvum_PYR-GCK TWQFRDVVIPNVALNAVAGRPKEEYGLEPQGLDEIRPGCWQVDERVKDMN
Mvan_2022|M.vanbaalenii_PYR-1 TWQFRDVVIPNVALNAVAGRPKEEYGLEPQGLDEIRPGCWQVDERVKDMN
MMAR_4742|M.marinum_M MWKFRDTVIPNVALNAVAGRPKEEYGLEPQGLDEIRPGCYNVDERIKDMN
MSMEG_4837|M.smegmatis_MC2_155 TWQFRDTVIPNVALNAVAGRPKEEYGLEPQGLDEIRKGCYDPNERVKDMN
TH_2339|M.thermoresistible__bu QWMYQGRPQGVSGLNAVVSWPPEEWGRNPARFAEMRPGVYDVHERVRDMN
MUL_3143|M.ulcerans_Agy99 VWVYDGQVLPNVGFNAVVGRPVSEYGFEPVRFDEMRRGAWDIHERIKDMD
MAV_1874|M.avium_104 --------------------------------------------------
Mflv_4324|M.gilvum_PYR-GCK AGGILGSMCFPSFP-GFAGR--LFATEDPEFSLALVQAYNDWHVEEWCGA
Mvan_2022|M.vanbaalenii_PYR-1 AGGILGSMCFPSFP-GFAGR--LFATEDAEFSLALVQAYNDWHVEEWCGA
MMAR_4742|M.marinum_M AGGILASICFPSFP-GFAGR--LFATEDPDFSVALVQAYNDWHIDEWCGA
MSMEG_4837|M.smegmatis_MC2_155 AGGVLATMNFPSFP-GFAAR--LFATDDEEFSLALVQAYNDWHIDEWCAS
TH_2339|M.thermoresistible__bu RNGILASMCFPTFT-GFSAR--HLNMHREHVTLIMVSAYNDWHIDEWAGS
MUL_3143|M.ulcerans_Agy99 LNGVYASLNFPSFLPGFAGQRLQQVTKDPELAWAAVRAWNDWHLEAWAGP
MAV_1874|M.avium_104 -----------------------------------MKAWNDFYIDEWCAT
: *:**:::: *...
Mflv_4324|M.gilvum_PYR-GCK YPARFIPMTLPVIWDPEACAKEIRRNAARGVHSLTFSENPSAMGYPSFHD
Mvan_2022|M.vanbaalenii_PYR-1 YPARFIPMTLPVIWDPVACAAEIRRNAARGVHSLTFSENPSAMGYPSFHD
MMAR_4742|M.marinum_M YPARFVPMAIPVIWDAEACAAEVRRVAKKGVHALTFTENPAAMGYPSFHN
MSMEG_4837|M.smegmatis_MC2_155 NPGRFIPMAIPAIWNPGLAAAEVRRVAEKGVHSLTFTENPSTLGYPSFHD
TH_2339|M.thermoresistible__bu YPGRFIPIAILPTWNPEAMCAEIRRVAAKGCRAVTMPELPHLEGLPSYHD
MUL_3143|M.ulcerans_Agy99 YPERIIPCQLPWLLDPSAGAQLIHENAERGFRAVSFSENPAMLGLPSIHS
MAV_1874|M.avium_104 APDRYIPLAILPVWDIDATVAEAERVAAKGARTVSFPDSPVPMGLPSFHS
* * :* : : .. * :* :::::.: * * ** *.
Mflv_4324|M.gilvum_PYR-GCK FDHWKPMWDALVDTDTVLNVHIGSSGRLA-------------ITAPDAPM
Mvan_2022|M.vanbaalenii_PYR-1 FEHWKPMWDALVDTDTVLNVHIGSSGRLA-------------ITAPDAPM
MMAR_4742|M.marinum_M -EYWNPLWKALCDTNTVMNIHIGSSGRLA-------------ITAPDAPM
MSMEG_4837|M.smegmatis_MC2_155 LEYWRPLWQALVDTETVMNVHIGSSGKLA-------------ITAPDAPM
TH_2339|M.thermoresistible__bu EDYWGPVFRTLSEENVVMCLHIGTGFGAI-------------SMAPDAPI
MUL_3143|M.ulcerans_Agy99 -GHWDPMMAACAETGTVVNLHIGSSGSSP-------------STTDDAPA
MAV_1874|M.avium_104 -DHWDGLWRVCSETQMPVSLHFGSGSFVPGFSFSSMKPIAGQMVVPDAPF
:* : . : : :*:*:. . ***
Mflv_4324|M.gilvum_PYR-GCK DVMITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEGGTGWIPYFLERVD
Mvan_2022|M.vanbaalenii_PYR-1 DVMITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEGGTGWIPYFLERVD
MMAR_4742|M.marinum_M DVMITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEGGTGWIPYFLERAD
MSMEG_4837|M.smegmatis_MC2_155 DVMITLQPMNIVQAAADLLWSAPIKEFPTLKIALSEGGTGWIPYFLDRVD
TH_2339|M.thermoresistible__bu DNMIILATQVSAMCAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLDRCD
MUL_3143|M.ulcerans_Agy99 DVPGVLFFAYAISAAVDWLYSGLPSRFPDLKICLSEGRIGWVAGLLDRLD
MAV_1874|M.avium_104 AVATTLFSSNLMWTTVDLLFSGKLQQFPDLQFSLAEGGIGWVPYILERSD
* : * *:. .:* *::.::** **:. *:* *
Mflv_4324|M.gilvum_PYR-GCK RTYEMHSTWTG-QDFKGKLP-SEVFREHFLTCFIADPVGVATRHQIGVDN
Mvan_2022|M.vanbaalenii_PYR-1 RTYEMHSTWTG-QDFKGKLP-SEVFREHFLTCFIADPVGVATRHQIGVDN
MMAR_4742|M.marinum_M RTFEMHSTWTH-QNFGGKIP-SEVFREHFLTCFISDKVGVALRNMIGIDN
MSMEG_4837|M.smegmatis_MC2_155 RTFEMHSTWTH-QNFGGKLP-SEVFREHFMTCFISDPVGVKNRHMIGIDN
TH_2339|M.thermoresistible__bu RHYTN-QKWLR-RDFGDKLP-SDVFREHSLACYVTDKTSLKLRHEIGIDI
MUL_3143|M.ulcerans_Agy99 HMLSYHEMYGTWRAMGESLTSAEVFTRNFWFCAVEDKSSFVQHYRIGTEN
MAV_1874|M.avium_104 YVWERHRYYQD-IDFDTRPS--DLFRKHFWGCFIDDMHGLKNRHEIGIDR
: : . ::* .: * : * .. : ** :
Mflv_4324|M.gilvum_PYR-GCK ICWEADYPHSDSMWPGAPEQLDEVLKANNVPDDEINKMTYENAMRWYHWD
Mvan_2022|M.vanbaalenii_PYR-1 ICWEADYPHSDSMWPGAPEQLDEVLKVNNVPDDEIDKMTYQNAMRWYHWD
MMAR_4742|M.marinum_M IAWEADYPHSDSMWPGAPEELWDVLSVNDVPDGEINKMTYENAMRWYSFD
MSMEG_4837|M.smegmatis_MC2_155 ICWEMDYPHSDSMWPGAPEELSAVFDTYDVPDDEINKITHENAMRLYHFD
TH_2339|M.thermoresistible__bu IAWECDYPHSDCFWPDAPEQVHAELRAAGADDFDINKITWENSCRFFSWD
MUL_3143|M.ulcerans_Agy99 IMVESDYPHCDSTWPHTQQTMHEQLDG--LPADVIRKITWENAARLYQHP
MAV_1874|M.avium_104 ITLEIDFPHSDSNWPNSRKRAAEVLAD--VPDDECSLIVEENARRMLNFP
* * *:**.*. ** : : : :. :*: *
Mflv_4324|M.gilvum_PYR-GCK PFTHIAKEQATVGALRKAAEGHDVSIQALSHHKEGERGGGAGHFDALNAA
Mvan_2022|M.vanbaalenii_PYR-1 PFTHIPKEQATVGALRKAAEGHDVSIQALSHHKEGERGGGAGHFDALNAA
MMAR_4742|M.marinum_M PFSHITREQATVGALRKAAEGHDVSVRALSHHKDARSGSSVAEFTANAKA
MSMEG_4837|M.smegmatis_MC2_155 PFAHVPKEQATVGALRKAAEGHDVSIRALS--KKDKTGASFADFQANAKA
TH_2339|M.thermoresistible__bu PFEHTPRAEATVGALRAKATDVDTTIRSRA-----EWAQLYEQKQQFAQA
MUL_3143|M.ulcerans_Agy99 VPVAIAQNPEAF--------------------------------------
MAV_1874|M.avium_104 RLTAA---------------------------------------------
Mflv_4324|M.gilvum_PYR-GCK ARGNSGA-
Mvan_2022|M.vanbaalenii_PYR-1 ARGNSGAD
MMAR_4742|M.marinum_M LTGNKD--
MSMEG_4837|M.smegmatis_MC2_155 VSGARD--
TH_2339|M.thermoresistible__bu --------
MUL_3143|M.ulcerans_Agy99 --------
MAV_1874|M.avium_104 --------