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PLQPWMEMISVDDHLIEHPKVWSDRLPRKYLEAGPKIIEWERPDTGQMCQVWEYEGRIYPYIGLNAVAGK KPEEYGIEPVRYDDMIPGCYDPKARVADMDIDGVQAMTCFPSFPRFAGAVFAEGEDKELAVLCSKAWNDF HLDEWAATAPDRFIPVAMLPFWDIEESVKEIHRVAGKGAKCVTFPDLPDKLGLPSVHSDHWDPVLSAMEE TGMVLAQHFGSGGFPPPIAPDAPFAVFITLMGTMSMTALTDWLFSHTLYRHPNLKIGLSEGGIGWIPYIL ERADSVWRKHRFYNNINQDHPPSYLWKKHFHGCFIEDDFGVEMRHSVGVDQITWECDYPHSDSFWPQSRE RAAQALEKVPDDEVHKIVELNARQFYNFPRAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1837 | - | - | 100% (383) | amidohydrolase 2 |
| M. avium 104 | MAV_2591 | - | e-126 | 56.84% (373) | amidohydrolase 2 |
| M. avium 104 | MAV_0907 | - | 2e-93 | 43.88% (376) | amidohydrolase 2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2441 | - | 5e-88 | 42.71% (377) | amidohydrolase 2 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0273 | - | 7e-91 | 43.92% (378) | amidohydrolase |
| M. smegmatis MC2 155 | MSMEG_4837 | - | 4e-87 | 43.24% (377) | amidohydrolase 2 |
| M. thermoresistible (build 8) | TH_2339 | - | 7e-77 | 37.97% (374) | amidohydrolase 2 |
| M. ulcerans Agy99 | MUL_3143 | - | 2e-77 | 39.26% (377) | amidohydrolase |
| M. vanbaalenii PYR-1 | Mvan_4211 | - | 5e-89 | 43.24% (377) | amidohydrolase 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2441|M.gilvum_PYR-GCK ----------------MDKNDMILISVDDHIVEPPDMFKNHLSKKYLDEA
Mvan_4211|M.vanbaalenii_PYR-1 MSRAPARKGGNGRSAVMNRDDMILISVDDHIVEPPDMFKNHLPRKYLDEA
MSMEG_4837|M.smegmatis_MC2_155 ----------------MNKDDMILISVDDHIIEPPDMFKNHLPAKYRDEA
MMAR_0273|M.marinum_M ----------------MNTDDMILISVDDHIVEPPDMFDNHLPAKYLRDA
TH_2339|M.thermoresistible__bu ------------MSHDLRPEDLILVSIDDHVVEPPDMFLRHVPAKYRDEA
MAV_1837|M.avium_104 --------------MPLQP-WMEMISVDDHLIEHPKVWSDRLPRKYLEAG
MUL_3143|M.ulcerans_Agy99 -----------MTDPPRARRRYTVISVDDHIVEPPDTFTGRLPQRFADRA
::*:***::* *. : ::. :: .
Mflv_2441|M.gilvum_PYR-GCK PRLVHNE-----DGSDTWQFRDVVIPNVALNAVAGRPKEEYGLEPQGLDE
Mvan_4211|M.vanbaalenii_PYR-1 PRLVHNP-----DGSDTWQFRDVVIPNVALNAVAGRPKEEYGLEPQGLDE
MSMEG_4837|M.smegmatis_MC2_155 PRLVHNP-----DGSDTWQFRDTVIPNVALNAVAGRPKEEYGLEPQGLDE
MMAR_0273|M.marinum_M PRLVRNP-----DGSDVWKFRDSVIPNPALNAVAGRPKEEYGLEPQGLDE
TH_2339|M.thermoresistible__bu PIVVTDE-----NGVDQWMYQGRPQGVSGLNAVVSWPPEEWGRNPARFAE
MAV_1837|M.avium_104 PKIIEWERPDTGQMCQVWEYEGRIYPYIGLNAVAGKKPEEYGIEPVRYDD
MUL_3143|M.ulcerans_Agy99 PRVVETD-----DGGQVWVYDGQVLPNVGFNAVVGRPVSEYGFEPVRFDE
* :: : : * : . .:***.. .*:* :* :
Mflv_2441|M.gilvum_PYR-GCK IRPGCWQVDERVKDMNAGGILGSMCFPSFP-GFAGRLFAT--EDPEFSLA
Mvan_4211|M.vanbaalenii_PYR-1 IRPGCWQVDERVKDMNAGGILGSMCFPSFP-GFAGRLFAT--EDAEFSLA
MSMEG_4837|M.smegmatis_MC2_155 IRKGCYDPNERVKDMNAGGVLATMNFPSFP-GFAARLFAT--DDEEFSLA
MMAR_0273|M.marinum_M IRPGCYQVDERVKDMNAGGILASICFPSFP-GFAGRRFAT--DDPDFSLA
TH_2339|M.thermoresistible__bu MRPGVYDVHERVRDMNRNGILASMCFPTFT-GFSARHLNM--HREHVTLI
MAV_1837|M.avium_104 MIPGCYDPKARVADMDIDGVQAMTCFPSFP-RFAGAVFAEG-EDKELAVL
MUL_3143|M.ulcerans_Agy99 MRRGAWDIHERIKDMDLNGVYASLNFPSFLPGFAGQRLQQVTKDPELAWA
: * :: . *: **: .*: . **:* *:. : . ..:
Mflv_2441|M.gilvum_PYR-GCK LVQAYNDWHVEEWCGAYPARFIPMTLPVIWDPEACAKEIRRNAARGVHSL
Mvan_4211|M.vanbaalenii_PYR-1 LVQAYNDWHVEEWCGAYPARFIPMTLPVIWDPEACAKEIRRNAARGVHSL
MSMEG_4837|M.smegmatis_MC2_155 LVQAYNDWHIDEWCASNPGRFIPMAIPAIWNPGLAAAEVRRVAEKGVHSL
MMAR_0273|M.marinum_M LIQAYNDWHIDQWCGAYPARFIPMALPVIWDAQACATEVRRVSKKGVHAL
TH_2339|M.thermoresistible__bu MVSAYNDWHIDEWAGSYPGRFIPIAILPTWNPEAMCAEIRRVAAKGCRAV
MAV_1837|M.avium_104 CSKAWNDFHLDEWAATAPDRFIPVAMLPFWDIEESVKEIHRVAGKGAKCV
MUL_3143|M.ulcerans_Agy99 AVRAWNDWHLEAWAGPYPERIIPCQLPWLLDPSAGAQLIHENAERGFRAV
*:**:*:: *... * *:** : : ::. : :* :.:
Mflv_2441|M.gilvum_PYR-GCK TFSENPSAMGYPSFHDFDHWKPMWDALVDTDTVLNVHIGSSGRLAITAPD
Mvan_4211|M.vanbaalenii_PYR-1 TFSENPSAMGYPSFHDFEHWKPMWDALVDTDTVLNVHIGSSGRLAITAPD
MSMEG_4837|M.smegmatis_MC2_155 TFTENPSTLGYPSFHDLEYWRPLWQALVDTETVMNVHIGSSGKLAITAPD
MMAR_0273|M.marinum_M TFTENPATMGYPSFHN-DYWNPLWKALCDTNTVMNIHFGSSGNLVTTAPD
TH_2339|M.thermoresistible__bu TMPELPHLEGLPSYHDEDYWGPVFRTLSEENVVMCLHIGTGFGAISMAPD
MAV_1837|M.avium_104 TFPDLPDKLGLPSVHS-DHWDPVLSAMEETGMVLAQHFGSGGFPPPIAPD
MUL_3143|M.ulcerans_Agy99 SFSENPAMLGLPSIHS-GHWDPMMAACAETGTVVNLHIGSSGSSPSTTDD
::.: * * ** *. :* *: : : *: *:*:. : *
Mflv_2441|M.gilvum_PYR-GCK APMDVMITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEGGTGWIPYFLE
Mvan_4211|M.vanbaalenii_PYR-1 APMDVMITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEGGTGWIPYFLE
MSMEG_4837|M.smegmatis_MC2_155 APMDVMITLQPMNIVQAAADLLWSAPIKEFPTLKIALSEGGTGWIPYFLD
MMAR_0273|M.marinum_M APIDVLMTLGPMNIVQAAADLLWSRPIKDYPDLKIGLSEGGTGWIPYFLE
TH_2339|M.thermoresistible__bu APIDNMIILATQVSAMCAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLD
MAV_1837|M.avium_104 APFAVFITLMGTMSMTALTDWLFSHTLYRHPNLKIGLSEGGIGWIPYILE
MUL_3143|M.ulcerans_Agy99 APADVPGVLFFAYAISAAVDWLYSGLPSRFPDLKICLSEGRIGWVAGLLD
** * . * *:. .* **: :*** **:. *:
Mflv_2441|M.gilvum_PYR-GCK RVDRTYEMHSTWTGQDFKGKLPS--EVFREHFLTCFIADPVGVATRHQIG
Mvan_4211|M.vanbaalenii_PYR-1 RVDRTYEMHSTWTGQDFKGKLPS--EVFREHFLTCFIADPVGVATRHQIG
MSMEG_4837|M.smegmatis_MC2_155 RVDRTFEMHSTWTHQNFGGKLPS--EVFREHFMTCFISDPVGVKNRHMIG
MMAR_0273|M.marinum_M RADRVFEMHSTWTHQDFGGKLPS--EVFREHFLACFISDPVGVKLRNMIG
TH_2339|M.thermoresistible__bu RCDRHYTN-QKWLRRDFGDKLPS--DVFREHSLACYVTDKTSLKLRHEIG
MAV_1837|M.avium_104 RADSVWRKHRFYNNIN-QDHPPS--YLWKKHFHGCFIEDDFGVEMRHSVG
MUL_3143|M.ulcerans_Agy99 RLDHMLSYHEMYGTWRAMGESLTSAEVFTRNFWFCAVEDKSSFVQHYRIG
* * : .. : :: .: * : * .. : :*
Mflv_2441|M.gilvum_PYR-GCK VDNICWEADYPHSDSMWPGAPEQLDEVLKANNVPDDEINKMTYENAMRWY
Mvan_4211|M.vanbaalenii_PYR-1 VDNICWEADYPHSDSMWPGAPEQLDEVLKVNSVPDDEIDKMTYQNAMRWY
MSMEG_4837|M.smegmatis_MC2_155 IDNICWEMDYPHSDSMWPGAPEELSAVFDTYDVPDDEINKITHENAMRLY
MMAR_0273|M.marinum_M IDNIAWEADYPHSDSMWPGAPEELGEVLTANSVPDLEVDKMTHLNAMRWY
TH_2339|M.thermoresistible__bu IDIIAWECDYPHSDCFWPDAPEQVHAELRAAGADDFDINKITWENSCRFF
MAV_1837|M.avium_104 VDQITWECDYPHSDSFWPQSRERAAQALEK--VPDDEVHKIVELNARQFY
MUL_3143|M.ulcerans_Agy99 TENIMVESDYPHCDSTWPHTQQTMHEQLDG--LPADVIRKITWENAARLY
: * * ****.*. ** : : : : *:. *: : :
Mflv_2441|M.gilvum_PYR-GCK HWDPFTHIAKEQATVGALRKAAEGHDVSIQALSNKEKTGTTFSDFAASAK
Mvan_4211|M.vanbaalenii_PYR-1 HWDPFTHIPKEQATVGALRKAAEGHDVSIQALSHKEKTGATFADFAARAK
MSMEG_4837|M.smegmatis_MC2_155 HFDPFAHVPKEQATVGALRKAAEGHDVSIRALSKKDKTGASFADFQANAK
MMAR_0273|M.marinum_M SFDPFSRIPREQATVGALRKAAAGHDVSTRPRS-QHKSGERTSILVEP--
TH_2339|M.thermoresistible__bu SWDPFEHTPRAEATVGALRAKATDVDTTIRSRAEWAQLYEQKQQFAQA--
MAV_1837|M.avium_104 NFP---------------RAA-----------------------------
MUL_3143|M.ulcerans_Agy99 QHP-------------VPVAIAQNPEAF----------------------
Mflv_2441|M.gilvum_PYR-GCK SISGNKD
Mvan_4211|M.vanbaalenii_PYR-1 EITGNTD
MSMEG_4837|M.smegmatis_MC2_155 AVSGARD
MMAR_0273|M.marinum_M -------
TH_2339|M.thermoresistible__bu -------
MAV_1837|M.avium_104 -------
MUL_3143|M.ulcerans_Agy99 -------