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MPLQDHHQIVSVDDHLVEHPRVWQDRLPEKWREQGPRIVELDGKHLWSYDGQVFPTIGLNAVAGKPPEEW GLDPVRYEDMIPGCYDPVARVADMDLDGVQAALCFPSFPGFGGGTFVRAEVNRPGFDGGSCYWISTSGWS VRFVA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_1872 | - | - | 100% (145) | amidohydrolase 2 |
M. avium 104 | MAV_2591 | - | 2e-52 | 89.90% (99) | amidohydrolase 2 |
M. avium 104 | MAV_1837 | - | 7e-45 | 60.32% (126) | amidohydrolase 2 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | - | - | - | - | - |
M. gilvum PYR-GCK | Mflv_2441 | - | 2e-25 | 44.04% (109) | amidohydrolase 2 |
M. tuberculosis H37Rv | - | - | - | - | - |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | - | - | - | - | - |
M. marinum M | MMAR_2618 | - | 1e-28 | 50.46% (109) | amidohydrolase |
M. smegmatis MC2 155 | MSMEG_4837 | - | 9e-27 | 45.61% (114) | amidohydrolase 2 |
M. thermoresistible (build 8) | TH_2339 | - | 1e-23 | 45.19% (104) | amidohydrolase 2 |
M. ulcerans Agy99 | MUL_3143 | - | 8e-29 | 50.46% (109) | amidohydrolase |
M. vanbaalenii PYR-1 | Mvan_4211 | - | 2e-26 | 43.86% (114) | amidohydrolase 2 |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_2441|M.gilvum_PYR-GCK -------------------------------MDKNDMILISVDDHIVEPP Mvan_4211|M.vanbaalenii_PYR-1 ---------------MSRAPARKGGNGRSAVMNRDDMILISVDDHIVEPP MSMEG_4837|M.smegmatis_MC2_155 -------------------------------MNKDDMILISVDDHIIEPP TH_2339|M.thermoresistible__bu ---------------------------MSHDLRPEDLILVSIDDHVVEPP MMAR_2618|M.marinum_M MKSIDELASDLSFTTAKTGADRSVTFLPDPPRARRRYTVISVDDHIVEPP MUL_3143|M.ulcerans_Agy99 --------------------------MTDPPRARRRYTVISVDDHIVEPP MAV_1872|M.avium_104 ------------------------------MPLQDHHQIVSVDDHLVEHP ::*:***::* * Mflv_2441|M.gilvum_PYR-GCK DMFKNHLSKKYLDEAPRLVHNEDGSDTWQFRDVVIPNVALNAVAGRPKEE Mvan_4211|M.vanbaalenii_PYR-1 DMFKNHLPRKYLDEAPRLVHNPDGSDTWQFRDVVIPNVALNAVAGRPKEE MSMEG_4837|M.smegmatis_MC2_155 DMFKNHLPAKYRDEAPRLVHNPDGSDTWQFRDTVIPNVALNAVAGRPKEE TH_2339|M.thermoresistible__bu DMFLRHVPAKYRDEAPIVVTDENGVDQWMYQGRPQGVSGLNAVVSWPPEE MMAR_2618|M.marinum_M DTFTGRLPQRFADRAPRVVETDDGGQVWVYDGQVLPNVGFNAVVGRPVSE MUL_3143|M.ulcerans_Agy99 DTFTGRLPQRFADRAPRVVETDDGGQVWVYDGQVLPNVGFNAVVGRPVSE MAV_1872|M.avium_104 RVWQDRLPEKWREQGPRIVEL-DGKHLWSYDGQVFPTIGLNAVAGKPPEE : ::. :: :..* :* :* . * : . .:***.. * .* Mflv_2441|M.gilvum_PYR-GCK YGLEPQGLDEIRPGCWQVDERVKDMNAGGILGSMCFPSFP-GFAGR--LF Mvan_4211|M.vanbaalenii_PYR-1 YGLEPQGLDEIRPGCWQVDERVKDMNAGGILGSMCFPSFP-GFAGR--LF MSMEG_4837|M.smegmatis_MC2_155 YGLEPQGLDEIRKGCYDPNERVKDMNAGGVLATMNFPSFP-GFAAR--LF TH_2339|M.thermoresistible__bu WGRNPARFAEMRPGVYDVHERVRDMNRNGILASMCFPTFT-GFSAR--HL MMAR_2618|M.marinum_M YGFEPVRFDEMRRGAWDIHERIKDMDLNGVYASLNFPSFLPGFAGQRLQQ MUL_3143|M.ulcerans_Agy99 YGFEPVRFDEMRRGAWDIHERIKDMDLNGVYASLNFPSFLPGFAGQRLQQ MAV_1872|M.avium_104 WGLDPVRYEDMIPGCYDPVARVADMDLDGVQAALCFPSFP-GFGGG---- :* :* :: * :: *: **: .*: .:: **:* **.. Mflv_2441|M.gilvum_PYR-GCK ATEDPEFSLALVQAYNDWHVEEWCGAYPARFIPMTLPVIWDPEACAKEIR Mvan_4211|M.vanbaalenii_PYR-1 ATEDAEFSLALVQAYNDWHVEEWCGAYPARFIPMTLPVIWDPEACAKEIR MSMEG_4837|M.smegmatis_MC2_155 ATDDEEFSLALVQAYNDWHIDEWCASNPGRFIPMAIPAIWNPGLAAAEVR TH_2339|M.thermoresistible__bu NMHREHVTLIMVSAYNDWHIDEWAGSYPGRFIPIAILPTWNPEAMCAEIR MMAR_2618|M.marinum_M VTKDPELAWAAVRAWNDWHLEAWAGPYPERIIPCQLPWLLDPSAGAQLIH MUL_3143|M.ulcerans_Agy99 VTKDPELAWAAVRAWNDWHLEAWAGPYPERIIPCQLPWLLDPSAGAQLIH MAV_1872|M.avium_104 ----------------------------------------------TFVR :: Mflv_2441|M.gilvum_PYR-GCK RNAARGVHSLTFSENPSAMGYPSFHDFDHWKPMWDALVDTDTVLNVHIGS Mvan_4211|M.vanbaalenii_PYR-1 RNAARGVHSLTFSENPSAMGYPSFHDFEHWKPMWDALVDTDTVLNVHIGS MSMEG_4837|M.smegmatis_MC2_155 RVAEKGVHSLTFTENPSTLGYPSFHDLEYWRPLWQALVDTETVMNVHIGS TH_2339|M.thermoresistible__bu RVAAKGCRAVTMPELPHLEGLPSYHDEDYWGPVFRTLSEENVVMCLHIGT MMAR_2618|M.marinum_M ENAERGFRAVSFSENPAMLGLPSIHS-GHWDPMMAACAETGTVVNLHIGS MUL_3143|M.ulcerans_Agy99 ENAERGFRAVSFSENPAMLGLPSIHS-GHWDPMMAACAETGTVVNLHIGS MAV_1872|M.avium_104 AEVNR----------------PGFDGGS----------------CYWIST . : *. .. *.: Mflv_2441|M.gilvum_PYR-GCK SGRLAITAPDAPMDVMITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEG Mvan_4211|M.vanbaalenii_PYR-1 SGRLAITAPDAPMDVMITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEG MSMEG_4837|M.smegmatis_MC2_155 SGKLAITAPDAPMDVMITLQPMNIVQAAADLLWSAPIKEFPTLKIALSEG TH_2339|M.thermoresistible__bu GFGAISMAPDAPIDNMIILATQVSAMCAQDLLWGPAMRNYPDLKFAFSEG MMAR_2618|M.marinum_M SGSSPSTTDDAPADVPGVLFFAYAISAAVDWLYSGLPSRFPDLKICLSEG MUL_3143|M.ulcerans_Agy99 SGSSPSTTDDAPADVPGVLFFAYAISAAVDWLYSGLPSRFPDLKICLSEG MAV_1872|M.avium_104 S------------------------------------------------- . Mflv_2441|M.gilvum_PYR-GCK GTGWIPYFLERVDRTYEMHSTWTG-QDFKGKLP-SEVFREHFLTCFIADP Mvan_4211|M.vanbaalenii_PYR-1 GTGWIPYFLERVDRTYEMHSTWTG-QDFKGKLP-SEVFREHFLTCFIADP MSMEG_4837|M.smegmatis_MC2_155 GTGWIPYFLDRVDRTFEMHSTWTH-QNFGGKLP-SEVFREHFMTCFISDP TH_2339|M.thermoresistible__bu GIGWIPFYLDRCDRHYTN-QKWLR-RDFGDKLP-SDVFREHSLACYVTDK MMAR_2618|M.marinum_M GIGWVAGLLDRLDHMLSYHEMYGTWRAMGESLTPAEVFTRNFWFCAVEDK MUL_3143|M.ulcerans_Agy99 RIGWVAGLLDRLDHMLSYHEMYGTWRAMGESLTSAEVFTRNFWFCAVEDK MAV_1872|M.avium_104 --GWSVRFVA---------------------------------------- ** : Mflv_2441|M.gilvum_PYR-GCK VGVATRHQIGVDNICWEADYPHSDSMWPGAPEQLDEVLKANNVPDDEINK Mvan_4211|M.vanbaalenii_PYR-1 VGVATRHQIGVDNICWEADYPHSDSMWPGAPEQLDEVLKVNSVPDDEIDK MSMEG_4837|M.smegmatis_MC2_155 VGVKNRHMIGIDNICWEMDYPHSDSMWPGAPEELSAVFDTYDVPDDEINK TH_2339|M.thermoresistible__bu TSLKLRHEIGIDIIAWECDYPHSDCFWPDAPEQVHAELRAAGADDFDINK MMAR_2618|M.marinum_M SSFVQHHRIGTENIMVESDYPHCDSTWPHTQQTMHEQLDG--LPADVIRK MUL_3143|M.ulcerans_Agy99 SSFVQHYRIGTENIMVESDYPHCDSTWPHTQQTMHEQLDG--LPADVIRK MAV_1872|M.avium_104 -------------------------------------------------- Mflv_2441|M.gilvum_PYR-GCK MTYENAMRWYHWDPFTHIAKEQATVGALRKAAEGHDVSIQALSNKEKTGT Mvan_4211|M.vanbaalenii_PYR-1 MTYQNAMRWYHWDPFTHIPKEQATVGALRKAAEGHDVSIQALSHKEKTGA MSMEG_4837|M.smegmatis_MC2_155 ITHENAMRLYHFDPFAHVPKEQATVGALRKAAEGHDVSIRALSKKDKTGA TH_2339|M.thermoresistible__bu ITWENSCRFFSWDPFEHTPRAEATVGALRAKATDVDTTIRSR-------A MMAR_2618|M.marinum_M ITWENAARLYQHPVPVAIAQNPEAF------------------------- MUL_3143|M.ulcerans_Agy99 ITWENAARLYQHPVPVAIAQNPEAF------------------------- MAV_1872|M.avium_104 -------------------------------------------------- Mflv_2441|M.gilvum_PYR-GCK TFSDFAASAKSISGNKD Mvan_4211|M.vanbaalenii_PYR-1 TFADFAARAKEITGNTD MSMEG_4837|M.smegmatis_MC2_155 SFADFQANAKAVSGARD TH_2339|M.thermoresistible__bu EWAQLYEQKQQFAQA-- MMAR_2618|M.marinum_M ----------------- MUL_3143|M.ulcerans_Agy99 ----------------- MAV_1872|M.avium_104 -----------------