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M. avium 104 MAV_1872 (-)

annotation: amidohydrolase 2
coordinates: 1865955 - 1866392
length: 145

MPLQDHHQIVSVDDHLVEHPRVWQDRLPEKWREQGPRIVELDGKHLWSYDGQVFPTIGLNAVAGKPPEEW
GLDPVRYEDMIPGCYDPVARVADMDLDGVQAALCFPSFPGFGGGTFVRAEVNRPGFDGGSCYWISTSGWS
VRFVA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_1872--100% (145)amidohydrolase 2
M. avium 104MAV_2591-2e-5289.90% (99) amidohydrolase 2
M. avium 104MAV_1837-7e-4560.32% (126) amidohydrolase 2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_2441-2e-2544.04% (109) amidohydrolase 2
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_2618-1e-2850.46% (109) amidohydrolase
M. smegmatis MC2 155MSMEG_4837-9e-2745.61% (114) amidohydrolase 2
M. thermoresistible (build 8)TH_2339-1e-2345.19% (104) amidohydrolase 2
M. ulcerans Agy99MUL_3143-8e-2950.46% (109) amidohydrolase
M. vanbaalenii PYR-1Mvan_4211-2e-2643.86% (114) amidohydrolase 2

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2441|M.gilvum_PYR-GCK          -------------------------------MDKNDMILISVDDHIVEPP
Mvan_4211|M.vanbaalenii_PYR-1       ---------------MSRAPARKGGNGRSAVMNRDDMILISVDDHIVEPP
MSMEG_4837|M.smegmatis_MC2_155      -------------------------------MNKDDMILISVDDHIIEPP
TH_2339|M.thermoresistible__bu      ---------------------------MSHDLRPEDLILVSIDDHVVEPP
MMAR_2618|M.marinum_M               MKSIDELASDLSFTTAKTGADRSVTFLPDPPRARRRYTVISVDDHIVEPP
MUL_3143|M.ulcerans_Agy99           --------------------------MTDPPRARRRYTVISVDDHIVEPP
MAV_1872|M.avium_104                ------------------------------MPLQDHHQIVSVDDHLVEHP
                                                                          ::*:***::* *

Mflv_2441|M.gilvum_PYR-GCK          DMFKNHLSKKYLDEAPRLVHNEDGSDTWQFRDVVIPNVALNAVAGRPKEE
Mvan_4211|M.vanbaalenii_PYR-1       DMFKNHLPRKYLDEAPRLVHNPDGSDTWQFRDVVIPNVALNAVAGRPKEE
MSMEG_4837|M.smegmatis_MC2_155      DMFKNHLPAKYRDEAPRLVHNPDGSDTWQFRDTVIPNVALNAVAGRPKEE
TH_2339|M.thermoresistible__bu      DMFLRHVPAKYRDEAPIVVTDENGVDQWMYQGRPQGVSGLNAVVSWPPEE
MMAR_2618|M.marinum_M               DTFTGRLPQRFADRAPRVVETDDGGQVWVYDGQVLPNVGFNAVVGRPVSE
MUL_3143|M.ulcerans_Agy99           DTFTGRLPQRFADRAPRVVETDDGGQVWVYDGQVLPNVGFNAVVGRPVSE
MAV_1872|M.avium_104                RVWQDRLPEKWREQGPRIVEL-DGKHLWSYDGQVFPTIGLNAVAGKPPEE
                                      :  ::. :: :..* :*   :* . * : .      .:***.. * .*

Mflv_2441|M.gilvum_PYR-GCK          YGLEPQGLDEIRPGCWQVDERVKDMNAGGILGSMCFPSFP-GFAGR--LF
Mvan_4211|M.vanbaalenii_PYR-1       YGLEPQGLDEIRPGCWQVDERVKDMNAGGILGSMCFPSFP-GFAGR--LF
MSMEG_4837|M.smegmatis_MC2_155      YGLEPQGLDEIRKGCYDPNERVKDMNAGGVLATMNFPSFP-GFAAR--LF
TH_2339|M.thermoresistible__bu      WGRNPARFAEMRPGVYDVHERVRDMNRNGILASMCFPTFT-GFSAR--HL
MMAR_2618|M.marinum_M               YGFEPVRFDEMRRGAWDIHERIKDMDLNGVYASLNFPSFLPGFAGQRLQQ
MUL_3143|M.ulcerans_Agy99           YGFEPVRFDEMRRGAWDIHERIKDMDLNGVYASLNFPSFLPGFAGQRLQQ
MAV_1872|M.avium_104                WGLDPVRYEDMIPGCYDPVARVADMDLDGVQAALCFPSFP-GFGGG----
                                    :* :*    ::  * ::   *: **: .*: .:: **:*  **..     

Mflv_2441|M.gilvum_PYR-GCK          ATEDPEFSLALVQAYNDWHVEEWCGAYPARFIPMTLPVIWDPEACAKEIR
Mvan_4211|M.vanbaalenii_PYR-1       ATEDAEFSLALVQAYNDWHVEEWCGAYPARFIPMTLPVIWDPEACAKEIR
MSMEG_4837|M.smegmatis_MC2_155      ATDDEEFSLALVQAYNDWHIDEWCASNPGRFIPMAIPAIWNPGLAAAEVR
TH_2339|M.thermoresistible__bu      NMHREHVTLIMVSAYNDWHIDEWAGSYPGRFIPIAILPTWNPEAMCAEIR
MMAR_2618|M.marinum_M               VTKDPELAWAAVRAWNDWHLEAWAGPYPERIIPCQLPWLLDPSAGAQLIH
MUL_3143|M.ulcerans_Agy99           VTKDPELAWAAVRAWNDWHLEAWAGPYPERIIPCQLPWLLDPSAGAQLIH
MAV_1872|M.avium_104                ----------------------------------------------TFVR
                                                                                    ::

Mflv_2441|M.gilvum_PYR-GCK          RNAARGVHSLTFSENPSAMGYPSFHDFDHWKPMWDALVDTDTVLNVHIGS
Mvan_4211|M.vanbaalenii_PYR-1       RNAARGVHSLTFSENPSAMGYPSFHDFEHWKPMWDALVDTDTVLNVHIGS
MSMEG_4837|M.smegmatis_MC2_155      RVAEKGVHSLTFTENPSTLGYPSFHDLEYWRPLWQALVDTETVMNVHIGS
TH_2339|M.thermoresistible__bu      RVAAKGCRAVTMPELPHLEGLPSYHDEDYWGPVFRTLSEENVVMCLHIGT
MMAR_2618|M.marinum_M               ENAERGFRAVSFSENPAMLGLPSIHS-GHWDPMMAACAETGTVVNLHIGS
MUL_3143|M.ulcerans_Agy99           ENAERGFRAVSFSENPAMLGLPSIHS-GHWDPMMAACAETGTVVNLHIGS
MAV_1872|M.avium_104                AEVNR----------------PGFDGGS----------------CYWIST
                                      . :                *. ..                     *.:

Mflv_2441|M.gilvum_PYR-GCK          SGRLAITAPDAPMDVMITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEG
Mvan_4211|M.vanbaalenii_PYR-1       SGRLAITAPDAPMDVMITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEG
MSMEG_4837|M.smegmatis_MC2_155      SGKLAITAPDAPMDVMITLQPMNIVQAAADLLWSAPIKEFPTLKIALSEG
TH_2339|M.thermoresistible__bu      GFGAISMAPDAPIDNMIILATQVSAMCAQDLLWGPAMRNYPDLKFAFSEG
MMAR_2618|M.marinum_M               SGSSPSTTDDAPADVPGVLFFAYAISAAVDWLYSGLPSRFPDLKICLSEG
MUL_3143|M.ulcerans_Agy99           SGSSPSTTDDAPADVPGVLFFAYAISAAVDWLYSGLPSRFPDLKICLSEG
MAV_1872|M.avium_104                S-------------------------------------------------
                                    .                                                 

Mflv_2441|M.gilvum_PYR-GCK          GTGWIPYFLERVDRTYEMHSTWTG-QDFKGKLP-SEVFREHFLTCFIADP
Mvan_4211|M.vanbaalenii_PYR-1       GTGWIPYFLERVDRTYEMHSTWTG-QDFKGKLP-SEVFREHFLTCFIADP
MSMEG_4837|M.smegmatis_MC2_155      GTGWIPYFLDRVDRTFEMHSTWTH-QNFGGKLP-SEVFREHFMTCFISDP
TH_2339|M.thermoresistible__bu      GIGWIPFYLDRCDRHYTN-QKWLR-RDFGDKLP-SDVFREHSLACYVTDK
MMAR_2618|M.marinum_M               GIGWVAGLLDRLDHMLSYHEMYGTWRAMGESLTPAEVFTRNFWFCAVEDK
MUL_3143|M.ulcerans_Agy99           RIGWVAGLLDRLDHMLSYHEMYGTWRAMGESLTSAEVFTRNFWFCAVEDK
MAV_1872|M.avium_104                --GWSVRFVA----------------------------------------
                                      **    :                                         

Mflv_2441|M.gilvum_PYR-GCK          VGVATRHQIGVDNICWEADYPHSDSMWPGAPEQLDEVLKANNVPDDEINK
Mvan_4211|M.vanbaalenii_PYR-1       VGVATRHQIGVDNICWEADYPHSDSMWPGAPEQLDEVLKVNSVPDDEIDK
MSMEG_4837|M.smegmatis_MC2_155      VGVKNRHMIGIDNICWEMDYPHSDSMWPGAPEELSAVFDTYDVPDDEINK
TH_2339|M.thermoresistible__bu      TSLKLRHEIGIDIIAWECDYPHSDCFWPDAPEQVHAELRAAGADDFDINK
MMAR_2618|M.marinum_M               SSFVQHHRIGTENIMVESDYPHCDSTWPHTQQTMHEQLDG--LPADVIRK
MUL_3143|M.ulcerans_Agy99           SSFVQHYRIGTENIMVESDYPHCDSTWPHTQQTMHEQLDG--LPADVIRK
MAV_1872|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_2441|M.gilvum_PYR-GCK          MTYENAMRWYHWDPFTHIAKEQATVGALRKAAEGHDVSIQALSNKEKTGT
Mvan_4211|M.vanbaalenii_PYR-1       MTYQNAMRWYHWDPFTHIPKEQATVGALRKAAEGHDVSIQALSHKEKTGA
MSMEG_4837|M.smegmatis_MC2_155      ITHENAMRLYHFDPFAHVPKEQATVGALRKAAEGHDVSIRALSKKDKTGA
TH_2339|M.thermoresistible__bu      ITWENSCRFFSWDPFEHTPRAEATVGALRAKATDVDTTIRSR-------A
MMAR_2618|M.marinum_M               ITWENAARLYQHPVPVAIAQNPEAF-------------------------
MUL_3143|M.ulcerans_Agy99           ITWENAARLYQHPVPVAIAQNPEAF-------------------------
MAV_1872|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_2441|M.gilvum_PYR-GCK          TFSDFAASAKSISGNKD
Mvan_4211|M.vanbaalenii_PYR-1       TFADFAARAKEITGNTD
MSMEG_4837|M.smegmatis_MC2_155      SFADFQANAKAVSGARD
TH_2339|M.thermoresistible__bu      EWAQLYEQKQQFAQA--
MMAR_2618|M.marinum_M               -----------------
MUL_3143|M.ulcerans_Agy99           -----------------
MAV_1872|M.avium_104                -----------------