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LKRLGGWDAVLLYNETPNLHQHTLKIAVVDATDCDGFGFDLFRQTLARRLHLLEPLRYQLTEIRGRIHRA MWLENCDVDLDFHVRRTQIRSPGGRRELDAAIGEVASTPLDRSRPLWEFHFVEGMADNRFAIIGKVHHAL ADGVASANLLARGLDLPNAPQPARDDYRADPYPSNGVLIRAALRDHAEHVRELPRLVRDTVKGVRRVRRK SRSAPGLARNFNPPATFLNHVVSPGRTFASTTLDLAAVKAVGKQLGVTINDMVLAITAGALRALLLEYDG HADQPILAGVPMSIDTSLERISGNALGTVVVSLPVHVADPLEWVRLARIGATIGKENTALLGPDLVSRWA GYAPPRLTERLFRRIATSGSGNKLINVPVSNVPGPRQPGRIACAPVVQFLSVGPLTFGAGVNITVWSYVD QLNISVLADDVTFEDPHQVTDTMVEAFDLVRQAAGMPAETRP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1847 | - | - | 100% (462) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. avium 104 | MAV_4952 | - | e-142 | 55.90% (458) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. avium 104 | MAV_2240 | - | 5e-62 | 32.06% (471) | acyltransferase, ws/dgat/mgat subfamily protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0227 | - | 9e-73 | 53.81% (236) | hypothetical protein Mb0227 |
| M. gilvum PYR-GCK | Mflv_2428 | - | 1e-156 | 59.06% (469) | hypothetical protein Mflv_2428 |
| M. tuberculosis H37Rv | Rv0221 | - | 1e-142 | 54.66% (461) | hypothetical protein Rv0221 |
| M. leprae Br4923 | MLBr_01244 | - | 6e-22 | 24.09% (411) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_0507 | - | 1e-64 | 32.76% (464) | hypothetical protein MAB_0507 |
| M. marinum M | MMAR_0464 | - | 1e-146 | 56.40% (461) | hypothetical protein MMAR_0464 |
| M. smegmatis MC2 155 | MSMEG_0290 | - | 1e-150 | 55.34% (459) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. thermoresistible (build 8) | TH_3760 | - | 1e-147 | 55.53% (461) | PUTATIVE Diacylglycerol O-acyltransferase |
| M. ulcerans Agy99 | MUL_1818 | - | 3e-59 | 32.33% (467) | hypothetical protein MUL_1818 |
| M. vanbaalenii PYR-1 | Mvan_0228 | - | 1e-150 | 55.79% (466) | hypothetical protein Mvan_0228 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1847|M.avium_104 ----------MKRLGGWDAVLLYNET-PNLHQHTLKIAVVDAT------D
Mflv_2428|M.gilvum_PYR-GCK --------MSMRRLNGMDAMLLYSET-PNLHTHTLKVAVIDATGYSAE-H
TH_3760|M.thermoresistible__bu ----------VKRLQGWDAVLLYSET-PNVHMHTLKVAVIDLSDVTHP--
Mvan_0228|M.vanbaalenii_PYR-1 ----------MKRLSGWDAVLLYSET-PNVHMHTLKLAVIELDDTFAREG
MSMEG_0290|M.smegmatis_MC2_155 ----------MQRLSGWDAFLLYSET-PNVHMHTLKIAIIDLEGIGDR--
Mb0227|M.bovis_AF2122/97 ----------MKRLSGWDAVLLYSET-PNVHMHTLKVAVIELDSDRQE--
Rv0221|M.tuberculosis_H37Rv ----------MKRLSGWDAVLLYSET-PNVHMHTLKVAVIELDSDRQE--
MMAR_0464|M.marinum_M ----------MKRLSGWDAVLLYSET-PNVHMHTLKVAVIELDPDRRA--
MAB_0507|M.abscessus_ATCC_1997 ----------MQRLSGVDAAFWHAET-AGWHMHIGGLSIYDPTDAPDY--
MUL_1818|M.ulcerans_Agy99 ----------MRRLSSVDAAFWSAET-AGWHMHVGALAICDPTDAPDY--
MLBr_01244|M.leprae_Br4923 MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDTTPDWNR--
. .* . * : *: . : : : :
MAV_1847|M.avium_104 CDGFGFDLFRQTLARRLHLLEPLRYQLTEIRGRIHRAMWLENCDVDLDFH
Mflv_2428|M.gilvum_PYR-GCK GGEYGFDAFRQTIARRLHLLEPLRYRLIDIPWRLHHPMWLQDCPVDLDYH
TH_3760|M.thermoresistible__bu ---FGLEDFRKVIASRLYKLDPFRYQLVEIPFKFHHPMWRENCEVDLDHH
Mvan_0228|M.vanbaalenii_PYR-1 GATFGVEELRKVIHGRLYKLDPFRYQLIDIPFKFHHPMWRENAEVDLEYH
MSMEG_0290|M.smegmatis_MC2_155 --TFGVEDFRKVLRGRLHKLDPFRFQLVDIPFKFHHPMWRENCDVDLEYH
Mb0227|M.bovis_AF2122/97 ---FGVDAFREVIAGRLHKLEPLGYQLVDVPLKFHHPMWREHCQVDLNYH
Rv0221|M.tuberculosis_H37Rv ---FGVDAFREVIAGRLHKLEPLGYQLVDVPLKFHHPMWREHCQVDLNYH
MMAR_0464|M.marinum_M ---FGVDAFRAVIGERMAKLEPFGYQLVDIPFKFHHPMWREHCEVDLDYH
MAB_0507|M.abscessus_ATCC_1997 ----SFERVRALIVERLPSMPQLRWRVTDVPLGLDRPWFVEDEELDPDFH
MUL_1818|M.ulcerans_Agy99 ----SFQRLRELLIERLPEIPQLRWRVTGAPLGLDRPWFVEDQDLDVDFH
MLBr_01244|M.leprae_Br4923 --------FRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFH
.* : : : :: . : . .: :.*
MAV_1847|M.avium_104 VRRTQIRSPGGRRELDAAIGEVASTPLDRSRPLWEFHFVEGMADNRFAII
Mflv_2428|M.gilvum_PYR-GCK LRRVRVPAPGGRRELDRVIGEIASTPLDRTRPLWEFHFAEGMADNRFALI
TH_3760|M.thermoresistible__bu IRGMRVDPPGGRRELDEAVGRIASTPLDRRYPLWEMYFVEGLANGRVAVV
Mvan_0228|M.vanbaalenii_PYR-1 VRSCRVDAPGGRRELDEAVGRIASTPLDRSRPLWEMYLIEGLAGGRIAVL
MSMEG_0290|M.smegmatis_MC2_155 VRPWQVRAPGGRRELDEAIGEIAGTPLDRSRPLWEMYFVEGLAGGRIAVV
Mb0227|M.bovis_AF2122/97 IRPWRLRAPGGRRELDEAVGEIASTPLNRDHPLWEMYFVEGLANHRIAVV
Rv0221|M.tuberculosis_H37Rv IRPWRLRAPGGRRELDEAVGEIASTPLNRDHPLWEMYFVEGLANHRIAVV
MMAR_0464|M.marinum_M IRPWQLRPPGGRRELDEAIGEIASTPLDRRYPLWEMYFVEGLANHRVAVV
MAB_0507|M.abscessus_ATCC_1997 IRRIGVPAPGGRKELEELAGRLMSYKLDRSRPLWELWVIEGVEGGRVATL
MUL_1818|M.ulcerans_Agy99 VRRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWELWVIEGVEGGRIATL
MLBr_01244|M.leprae_Br4923 VRRVRVPDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAML
:* : ** :*: : :: *** . **: * * :
MAV_1847|M.avium_104 GKVHHALADGVASANLLARGLDLPNAPQPARDDYRADP-YPSNGVLIRAA
Mflv_2428|M.gilvum_PYR-GCK GKVHHTLADGVASANLLARLMDLVDAPQDEREDPPAGCDDPSTLDLLREA
TH_3760|M.thermoresistible__bu GKIHHALADGVASGNLMARGMDLQPGPQRDHTFYRTDP-PPGRSHLVRTA
Mvan_0228|M.vanbaalenii_PYR-1 GKIHHALADGVASANLLARGMDLQDSPQADRDSYATDP-APTRGELVRSA
MSMEG_0290|M.smegmatis_MC2_155 NKIHHALADGIASANLLARGMDLREGPQRDRDSYVTDP-EPSKGELVRTA
Mb0227|M.bovis_AF2122/97 AKIHHALADGVASANMMARGMDLLPGPEVGR--YVPDP-APTKRQLLSAA
Rv0221|M.tuberculosis_H37Rv AKIHHALADGVASANMMARGMDLLPGPEVGR--YVPDP-APTKRQLLSAA
MMAR_0464|M.marinum_M GKIHHALADGVASANLMARGMDLLPGPEGDP--YVSDP-APTKRELMSSA
MAB_0507|M.abscessus_ATCC_1997 TKMHHAIVDGVSGAGLGEILLDIAPEPRPAPDDTVGSLVGLGLPSRERIL
MUL_1818|M.ulcerans_Agy99 TKMHHAIVDGVSGAGLGEILLDVTPEPRPPQEETVG-FVGFQIPRLERRA
MLBr_01244|M.leprae_Br4923 LQISHAITDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRNDLMLQG
:: *::.**:.. : *: *
MAV_1847|M.avium_104 LRDHAEHVR-----ELPRLVRDTVKGVRRVRRKS------RSAPGLARNF
Mflv_2428|M.gilvum_PYR-GCK QLDHFRNIV-----ELPSLVADAARGAARLRKRAK---ERREVPGLAKPF
TH_3760|M.thermoresistible__bu FVDHLRQIG-----RIPSVMRYTYDGLRRVHRST-----RKLSPELTRPF
Mvan_0228|M.vanbaalenii_PYR-1 FTDHLRQIA-----KLPGVVRYTAQGVRRVQRSE-----RKLSPELTRPF
MSMEG_0290|M.smegmatis_MC2_155 FADHMRQIG-----RIPATIRYTAQGVARVRRSS-----RKLSPELTRPF
Mb0227|M.bovis_AF2122/97 FIDHLRHLG-----RIPATIRYTTQGLGRVRRSS-----RKLSPALTMPF
Rv0221|M.tuberculosis_H37Rv FIDHLRHLG-----RIPATIRYTTQGLGRVRRSS-----RKLSPALTMPF
MMAR_0464|M.marinum_M FLDHLRHLG-----RIPATMRYTAQGLARVRRSS-----RKLSPELTRPF
MAB_0507|M.abscessus_ATCC_1997 LSALVNVGV-----KTPYRVARLVQQTVRQQLAV-----FGMERKSPGYF
MUL_1818|M.ulcerans_Agy99 VGALINVGI-----MTPFRIARLVEQTVRQQIAA-----LGVSARPPRYF
MLBr_01244|M.leprae_Br4923 INHLPVALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVLSQ
. *
MAV_1847|M.avium_104 NPPATFLNHVVSPGRTFASTTLDLAAVKAVGKQLGVTINDMVLAITAGAL
Mflv_2428|M.gilvum_PYR-GCK NAPPTFLNHVVSPVRTFATATLALSEVKETAKHLGVTFNDIVLAVAAGGL
TH_3760|M.thermoresistible__bu TPPPTFLNHKIDATRTFATATLALSDVKATSRHLGVTINDLVLALSAGAL
Mvan_0228|M.vanbaalenii_PYR-1 TPPPTFMNHMVDATRRFATATVALDDVKQTGKQLGVTINDMVLAMSAGAL
MSMEG_0290|M.smegmatis_MC2_155 TPPPSFINHMITSKRKFATATIALADAKETSKKLGITLNDLVLAMSSGAL
Mb0227|M.bovis_AF2122/97 TPPPTFMNR----------------------------------------I
Rv0221|M.tuberculosis_H37Rv TPPPTFMNHRLTPERRFATATLALIDVKATAKLLGATINDMVLAMSTGAL
MMAR_0464|M.marinum_M TPPPTFMNHMLTPQRRFATATLALADVKQTGKQLGATINDMVLAMSTGAL
MAB_0507|M.abscessus_ATCC_1997 EAPHTRFNAPVSPHRRISGARLDLARVKALKDAFGVKVNDVVLAIVAGAV
MUL_1818|M.ulcerans_Agy99 DAPKTRFNAHVSPHRRVSGCRIELARAKAVKDAFGVKLNDVVLATVAGAA
MLBr_01244|M.leprae_Br4923 AAEPSPLLRQRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGAL
. : :
MAV_1847|M.avium_104 RALLLEYDGHADQPILAGVPMSI-DTSLERISGNALGTVVVSLPVHVADP
Mflv_2428|M.gilvum_PYR-GCK RELLLRYDGRADRPIMATVPVST-DKSTDRVTGNEIGGMMVSLPVHVDDP
TH_3760|M.thermoresistible__bu RKLLLRYDGHADHPLLASVPVSF-DFSPDRICGNYFTGMLVALPVDTAEP
Mvan_0228|M.vanbaalenii_PYR-1 RKLLLRYDGRADHALLASVPVSF-DFSRDRISGNYFTGVLVSLPVDVEDP
MSMEG_0290|M.smegmatis_MC2_155 RTLQLRYDGRADHPLLASVPMSF-DFSPDRIWGNRFSGVLVALPVDVADT
Mb0227|M.bovis_AF2122/97 KKPLSKPSGRPP-PHTNRAPSS----------------MPLAM-------
Rv0221|M.tuberculosis_H37Rv RTLLLRYDGKAE-PLLASVPVSY-DFSPERISGNRFTGMLVALPADSDDP
MMAR_0464|M.marinum_M RNLLLRYDGRAE-PLLASVPVSY-DFSPDRISGNYFSGMMVALPTDCADP
MAB_0507|M.abscessus_ATCC_1997 RDYLAKRDEFPDKPLIVQIPVSVRTEETDGVVGNQVSSMTVSLATDIDDP
MUL_1818|M.ulcerans_Agy99 REYLKKRDELPAKPLIAQIPVSTRTDQTKEDVGNQISSMTASLATHINDP
MLBr_01244|M.leprae_Br4923 RRYHEALG-VSISTLPMAVPVNV-RTEADVVGSNRFVGVTLAAPLGTNDP
: . . . * . : :
MAV_1847|M.avium_104 LEWVRLARIGATIGKENTALLGPDLVSRWAGYAPPRLTERLFRRIATSGS
Mflv_2428|M.gilvum_PYR-GCK LERVELTAVATTRAKENNDLLGPTLQGRFLEYLPPPLAPTLFRAQSKRAD
TH_3760|M.thermoresistible__bu LDRIRATRDAALLAKESHQLIGPELISRWSQYLPPAPAERLFGWLSRIDG
Mvan_0228|M.vanbaalenii_PYR-1 LERVSAAHTAAAAGKESNNLIGPELVSRWSAYFPPAPAEAMFRWLSNKDG
MSMEG_0290|M.smegmatis_MC2_155 GERVRRTREAANLAKESHQLIGPELVARWAAYMPPVPVEALFKRLSSKDG
Mb0227|M.bovis_AF2122/97 --------------------------------------------------
Rv0221|M.tuberculosis_H37Rv LQRVRVCHENAVSAKESHQLLGPELISRWAAYWPPAGAEALFRWLSERDG
MMAR_0464|M.marinum_M LERVQACHENALSAKESHQLLGPELISRWAAYWPPGATEAAFRWASSRDG
MAB_0507|M.abscessus_ATCC_1997 AERIQAIYEGTQGAKEMARAMSAHQIMGLTDTTPPGLLQLAARAYTASGL
MUL_1818|M.ulcerans_Agy99 AERLKAIHESTQNAKEMAKALSAHQIMGLTETTPPGLLHLAARAYTATGL
MLBr_01244|M.leprae_Br4923 AARMQKIRSQMTQRRDEPAMNIIGSLAPLMTVLPASVLDFIVDSVASS--
MAV_1847|M.avium_104 GN--KLINVPVSNVPGPRQPGRIACAPVVQFLSVGPLTFGAGVNITVWSY
Mflv_2428|M.gilvum_PYR-GCK HN--RLMNVAISNVPGPRQRGHVGGAPVSEIYSVGVLSAGSAFNMTVWSY
TH_3760|M.thermoresistible__bu QN--KIQNLTVSNVMGPKERGRVGGALVTEIYSVGPLTAASGLNITVWSY
Mvan_0228|M.vanbaalenii_PYR-1 QN--KVMNLPISNVPGPRERARVGGALVTEIYSVGPLTAGSGLNITVWSY
MSMEG_0290|M.smegmatis_MC2_155 QN--KVLNLNISNVPGPRERGKVGGATVTELYSVGPITAGSGLNITVWSY
Mb0227|M.bovis_AF2122/97 --------------------------------------------------
Rv0221|M.tuberculosis_H37Rv QN--KVLNLNISNVPGPRERGRVGAALVTEIYSVGPLTAGSGLNITVWSY
MMAR_0464|M.marinum_M QN--KVLNLNISNVPGPREHGRVGGALVTEIYSVGPLTAGSGLNITVWSY
MAB_0507|M.abscessus_ATCC_1997 SRNLAPINLVLSNVPGPSFPLYMAGARLESMIPLGPPVMDVALNITCFSY
MUL_1818|M.ulcerans_Agy99 SHNLAPINLVVSNVPGPQFPLYMAGARLDSLVPLGPPVMDVALNITCFSY
MLBr_01244|M.leprae_Br4923 -------DVNASNIPAYPGDTYFAGAKILRQYGIGPR-PGVAMMAVLMSR
MAV_1847|M.avium_104 VDQLNISVLADDVTFEDPHQVTDTMVEAFDLVRQAAGMPAETRP------
Mflv_2428|M.gilvum_PYR-GCK VDQLDIAVLSDDRTFNDPHEATDAMVHAFDELRQVCGLARPTTVDTAMAP
TH_3760|M.thermoresistible__bu VDQLNISVLSDGSTFDDPHEVTDAMVGEFIEIRGAAGLPGELTVVETAMA
Mvan_0228|M.vanbaalenii_PYR-1 VDQINISVLSDGKTLDDPHELTTAMVDEFIEIRRAAGLSTELTVIETAMA
MSMEG_0290|M.smegmatis_MC2_155 VDQLNISVISDDATVDDPHEVTDAMLDEFREIRRTAGLSEKLTVVETAMP
Mb0227|M.bovis_AF2122/97 --------------------------------------------------
Rv0221|M.tuberculosis_H37Rv VDQLNISVLTDGSTVQDPHEVTAGMIADFIEIRRAAGLSVELTVVESAMA
MMAR_0464|M.marinum_M VDQLNISVLTDGATVEDPHEVTEAMMADFVEIRRAAGLSAELTVIEAAMA
MAB_0507|M.abscessus_ATCC_1997 LEHMDFGFVTTPEVAADIDEMADGLEAALVELEHAVGI------------
MUL_1818|M.ulcerans_Agy99 QEHLDFGFVTTPEVANDIDEMADLIEPALAELERAAGL------------
MLBr_01244|M.leprae_Br4923 GGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAA
MAV_1847|M.avium_104 -------------
Mflv_2428|M.gilvum_PYR-GCK APAPQP-------
TH_3760|M.thermoresistible__bu R------------
Mvan_0228|M.vanbaalenii_PYR-1 N------------
MSMEG_0290|M.smegmatis_MC2_155 Q------------
Mb0227|M.bovis_AF2122/97 -------------
Rv0221|M.tuberculosis_H37Rv QA-----------
MMAR_0464|M.marinum_M QARSMNEGAGSA-
MAB_0507|M.abscessus_ATCC_1997 -------------
MUL_1818|M.ulcerans_Agy99 -------------
MLBr_01244|M.leprae_Br4923 RSSGSPAGWLSSS